Objective:The study aimed to assess medication management compliance and mental health in elderly patients with hypertension.Method:The study evaluated medication compliance and mental health status of elderly hyperte...Objective:The study aimed to assess medication management compliance and mental health in elderly patients with hypertension.Method:The study evaluated medication compliance and mental health status of elderly hypertensive patients in China using simple random sampling.Data was collected using the Morisky Medication Compliance Questionnaire,Hospital Anxiety and Depression Scale,and a checklist.Ethical practices were strictly observed.Results:A study of 100 elderly hypertensive patients found poor drug management compliance,with female patients showing worse compliance.Female patients were more vulnerable to anxiety and depression.The study also found no significant association between gender,age,education level,marital status,living standards,and medication compliance.Barriers to medication management included food and daily necessities,lack of awareness about the importance of drug treatment,and basic family needs.The lowest-ranked barriers were lack of support from government health clinics,low income,and lack of family support.Conclusion:Based on the results,the study proposes an educational plan for elderly hypertensive patients and their families,to be evaluated and implemented by the hospital and township community service center.The plan aims to improve medication management and lifestyle modification compliance,encourage active participation,and provide access to medical and mental health clinics,support groups,and counseling services.展开更多
Background Rises in global warming and extreme weather occurrence make the risk of heat stress(HS)induced by high ambient temperatures more likely in high-yielding dairy cows,resulting in low milk quality and yield.In...Background Rises in global warming and extreme weather occurrence make the risk of heat stress(HS)induced by high ambient temperatures more likely in high-yielding dairy cows,resulting in low milk quality and yield.In ani-mals,oxygen is involved in many physiological and metabolic processes,but the effects of HS on oxygen metabolism remain unclear.Thus,the current study aimed to investigate how oxygen metabolism plays a role in health status of dairy cows by measuring the milk yield,milk composition,and blood biochemical variables of cows under different levels of HS:none(No-HS),mild(Mild-HS),and moderate HS(Mod-HS).Results The HS significantly increased rectal temperature(Ptreat<0.01)and respiration rate(Ptreat<0.01).Under Mod-HS,greater Na+(P<0.05)and lower total CO_(2),and pH(P<0.05)were observed relative to those under No-HS and Mild-HS.Oxygen concentrations in both coccygeal artery and mammary vein(Ptreat<0.01)were lower under Mod-HS than under No-HS.Coccygeal vein concentrations of heat shock protein 90(HSP90)(P<0.05)increased during Mod-HS compared with those in cows under No-HS.Malondialdehyde increased during Mod-HS,and glu-tathione peroxidase(P<0.01)increased during Mild-HS.Coccygeal vein concentrations of vascular endothelial growth factor(P<0.01),heme oxygenase-1(P<0.01),and hypoxia-inducible factor 1α(P<0.01)were greater in cows under Mod-HS than those under No-HS.Red blood cell count(P<0.01)and hemoglobin concentration(P<0.01)were lower in the coccygeal vein of dairy cows under Mild-and Mod-HS than those of cows under No-HS.Conclusions Exposure to HS negatively impacts the health status and lactation performance of dairy cows by limit-ing oxygen metabolism and transportation.However,the specific mechanism by which HS affects mammary function in cows remains unclear and requires further exploration.展开更多
Dietary factors play an important role in human health. Specifically, nutritional interventions may have an impact on the hypothalamic-pituitary axis resulting in positive health outcomes. A retrospective health statu...Dietary factors play an important role in human health. Specifically, nutritional interventions may have an impact on the hypothalamic-pituitary axis resulting in positive health outcomes. A retrospective health status survey of 386 respondents was conducted to investigate the potential of a dietary supplement, Nutrifii<sup>TM</sup> Renew, for improving various health outcomes in comparison to a multivitamin/mineral control group. Among those who ingested Renew, 95% reported experiencing at least some improvement in one or more health categories. Compared to the multivitamin/mineral group, the Renew group reported earlier and/or greater improvements in several health status categories including sleep, reproductive health, memory, energy/stamina, skin and hair quality, flexibility, exercise recovery and feeling rested in the morning. A clear majority (84.9%) of Renew consumers reported experiencing noticeable improvement in some aspect of their health within one month. Among those who felt an improvement in sleep, most reported experiencing a change within one week. These improvements were likely due to the synergistic effects of L-arginine, L-citrulline, L-lysine, and botanical extracts on nitric oxide production, growth hormone (GH) release, and sleep quality. The observed improvements in skin elasticity and hair growth may be related to increased GH levels and IGF-1 production. Overall, these findings suggest that Renew may have potential as a dietary intervention for improving various health outcomes beyond those provided by multivitamin/mineral supplementation alone. Further studies are needed to confirm these findings and elucidate the underlying mechanisms of action.展开更多
Background: The COVID-19 epidemic is a public health security event affecting the whole country, which has a certain impact on the development and current situation of the health field. As a special group, children an...Background: The COVID-19 epidemic is a public health security event affecting the whole country, which has a certain impact on the development and current situation of the health field. As a special group, children and adolescents need to receive attention and special care. Purpose: To study the health status of children and adolescents under the influence of COVID-19. Method: To collect and analyze the physical, mental and mental health data of 448 children aged 3 - 18 years in the Pediatric Medical Center of the Second Hospital of Jilin University since the COVID-19 outbreak, so as to grasp the physical, mental and mental health status and existing problems of children and adolescents under the impact of COVID-19 outbreak. Results: Food (seafood, mangoes, dairy products, animal protein, soy, peanuts, etc.) is the main allergen in the children and adolescents who participated in the survey, followed by inhalation (pollen, cat and dog hair, etc.). The diet was relatively normal, but there were still unhealthy eating behaviors, the detection rate was 5.36%. High calorie diet, high cholesterol diet, high salt diet, low protein diet, liquid diet in order from high to low, 85.27% of the normal water intake, drinking behavior was greatly affected by the family environment and school environment. The main problem affecting children’s digestion is constipation. Functional constipation accounts for more than 90% of children’s constipation, and its causes are mainly genetic factors, metabolic factors, mental factors, diet factors, etc. Genetic factors and unreasonable diet are the causes of children’s research results show that among 448 children and adolescents, 425 are in normal mental conditions. 94.87%;13, or 2.9%, were in the doldrums;There were 10 people in the state of hyperactivity, accounting for 2.23%, the main cause of functional. Conclusion: The health cloud platform was used to manage and analyze the data, in order to lay the foundation for the healthy growth and development of children and adolescents as well as the whole life cycle management of individual health.展开更多
The health status of the floating elderly population and the need of community management services are complex and important problems.Owing to the change of living environment and the insecure medical care,the mobile ...The health status of the floating elderly population and the need of community management services are complex and important problems.Owing to the change of living environment and the insecure medical care,the mobile elderly people have more health and psy-chological problems compared to the rest of the elderly population.Therefore,the community should take a variety of measures to meet their needs and help them to better adapt to the new living environment,and maintain their physical and mental health.This paper aims to summarize recent studies on the physical and emotional health problems of mobile elderly people and related community management service needs.展开更多
To investigate oral health status in the residents of Sichuan Province, southwest China, a cross-sectional study was performed using the latest Oral Health Survey Basic Methods recommended by the World Health Organiza...To investigate oral health status in the residents of Sichuan Province, southwest China, a cross-sectional study was performed using the latest Oral Health Survey Basic Methods recommended by the World Health Organization. A multistage stratified random cluster-sampling method was used to enroll participants from the following three groups: children aged 3-5 years, adolescents aged 12 years, and people aged 65-74 years. In these three groups, the mean numbers of teeth that were affected by caries were 3.28, 0.86 and 5.13, respectively, resulting in a prevalence of 63.47%, 37.20% and 83.20%, respectively. Relative to the high rate of decayed teeth, the prevalence of fillings was very low in all age groups (0.97%, 7.24% and 5.43%, respectively), In the 12-year-old adolescent group, only 3.61% had good pit and fissure sealing. In addition, the rate of dental fluorosis was 24.80%, and the Community Fluorosis Index value was 0.39. In the elder group, the community periodontal index was 2.92. The prevalence in the elderly of having lost at least one tooth was 75.54%. Additionally, 4.44% of these participants were edentulous. The incidence of dental prosthesis was 51.75%, the proportion with a removable partial denture, a fixed denture, full dentures, dental implants and an informal fixed bridge was 21.59%, 11.45%, 4.64%, 0 and 16.67%, respectively. In this study, 8.2% of the elderly participants were affected by different types of oral mucosal lesions. Among such lesions, recurrent aphthous ulcers were most prevalent (2.69%) and oral lichen planuses were second (1.6%). The conclusion presented in this survey is that oral diseases, especially dental caries and periodontal disease, are frequent and common in Sichuan province, China. Moreover, the treatment rate is very low, and primary prevention and treatment options are therefore urgently needed in this population.展开更多
Objectives:To describe the characteristics and relationships of social isolation and health promoting behaviors of Chinese older adults with different health statuses.Methods:Totally 485 older adults were recruited.Th...Objectives:To describe the characteristics and relationships of social isolation and health promoting behaviors of Chinese older adults with different health statuses.Methods:Totally 485 older adults were recruited.They were divided into three groups based on their health status:healthy group(n=72),group with one disease(n=183)and group with multimorbidity(n=230).Lubben Social Network Scale-6 and Health-Promoting Lifestyle Profile II were used to measure their social isolation and health-promoting behaviors,respectively.Results:Among the aged with one disease or multimorbidity,30.6%(56/183)and 31.7%(73/230)were socially isolated,respectively,based on the score of the Lubben Social Network Scale-6.The three groups differed significantly in health-promoting behaviors and scores on several subscales.The group with multimorbidity exhibited more social isolation and fewer health-promoting behaviors than other groups.Social isolation was among the factors adversely affecting health-promoting behaviors in older adults.Conclusions:Health care providers should help older adults with multimorbidity preserve the remaining abilities to improve health-promoting behaviors.Meanwhile,it is important to support healthy older adults to increase self-responsibility to achieve healthy aging.展开更多
The axial piston pump usually works under variable speed conditions.It is important to evaluate the health status of the axial piston pump under the variable speed condition.Aiming at the characteristic signals obtain...The axial piston pump usually works under variable speed conditions.It is important to evaluate the health status of the axial piston pump under the variable speed condition.Aiming at the characteristic signals obtained under different wear levels of the port plate,a feature signal extraction method under variable speed conditions is proposed.Firstly,the combination of complete ensemble empirical mode decomposition with adaptive noise(CEEMDAN)energy spectrum and fast spectral kurtosis principle is used to accurately extract the intrinsic mode function(IMF)component containing the sensitive information of the degraded feature.Then,the aspect ratio analysis method of the angle domain variational mode decomposition(VMD)is used to process the feature index containing the sensitive information of the degraded feature.In order to evaluate the health status of the axial piston pump under variable speed,the vibration reliability analysis method for axial piston pump based on Weibull proportional failure rate model is proposed.The experimental results show that the proposed method can accurately evaluate the health status of the axial piston pump.展开更多
Schools and parents should pay attention to health education for students' health awareness and good health habits, to establish a correct concept of health. School mental health education should be the first place; ...Schools and parents should pay attention to health education for students' health awareness and good health habits, to establish a correct concept of health. School mental health education should be the first place; school should create a positive learning environment for students to get knowledge and skills of exercising. Especially in the nine years of compulsory education stage, we should ensure necessary physical exercise, reasonable arrangements for extracurricular activities to improve students' physical fitness. We should improve the school' s sports facilities, and create a good campus atmosphere. Schools should actively carry out extra-curricular sports activities, improve the level of quality of physical education teachers, develop students' sports consciousness, and improve material conditions for the students to create a good learning environment, meanwhile, we should increase the content of education, and enrich the content of physical education to enable students to select and reach more sports.展开更多
Background: The Tubu are nomadic people who live in remote parts of the central Sahara, primarily in the Tibesti massif(Chad), and in both Northeastern Niger and Southern Libya. All of these areas are close to become ...Background: The Tubu are nomadic people who live in remote parts of the central Sahara, primarily in the Tibesti massif(Chad), and in both Northeastern Niger and Southern Libya. All of these areas are close to become conflict zones. However, no data about the Tubu's health and sanitary status are currently available, which would be of major concern if humanitarian interventions would become required.Methods: In 1970, the "Mission Anthropologique Belge au Niger"(MABN) investigated a Tubu tribe named Broaya that lived at Seguedine and Djado on the northeastern rim of the Tenere desert. One hundred fifty-one adult volunteers answered an oral questionnaire and underwent a medical examination, followed by the collection of blood thin films and samples of urine and stool. The environmental fauna of medical importance was also studied.Results: Albeit 43 year-old, these results have not been previously published. The estimated age of death for fathers was approximately 56 years, and that for mothers was 60 years. On average, each married woman had had 4.7 children. The overall perinatal mortality rate was 232 ‰, the overall infant mortality rate was 153 ‰, and the overall child mortality rate was 99 ‰. The mean height was 164.1 cm and 157.4 cm, the mean weight was 50.1 kg and 47.9kg, and the mean blood pressure was 131/78 mm Hg and 127/75 mm Hg for males and females, respectively. The physical examination found 6 cases of blindness(4.0%). Five subjects presented with an elevated blood pressure(3.3%), and 5(3.3%) displayed an abnormal thoracic auscultation evocative of tuberculosis or of an acute lung infection. The abdominal examination and renal palpation found 5 large masses(3.3%), and 2 subjects had a palpable enlarged spleen(1.3%). The blood thin films were fixed in methanol and subsequently examined in Toulouse. The search for blood parasites was negative. The urine samples were centrifuged and then microscopically examined in the field. No blood-fluke eggs were found. The stool samples were mixed with a preservative MIF solution and then stored to be examined later in Toulouse. Three subjects(2%) passed E. histolytica/E. dispar cysts in stools, 16(10.6%) were parasitized with Giardia sp. and 4(2.65%) were parasitized with Hymelepis nana. Two specimens of scorpions captured in the camp were subsequently identified as belonging to the harmful genus Androctonus or Leiurus. An investigation into the freshwater fauna was conducted in the marshy ponds surrounding the ghost city of Djado, and no intermediate snail hosts for schistosomiasis haematobium were found. Numerous nymphs of Ceratopogonidae, which are possible vectors for arboviruses of veterinarian importance, were collected, as were larvae and nymphs from two anopheline species, Anopheles hispaniola and An. multicolor, which are not efficient vectors for malaria.Conclusions: Infection-related blindness and trachoma, along with acute pulmonary infections and probably tuberculosis were the major health burden in this tribe. The harsh dry and hot climate may explain the low prevalence of soil-transmitted protozoan diseases or helminthiases.展开更多
Quality of Life (QOL) is a multiphase conception, including physical, mental and social factors, and can overall reflect health status of the human. At present, QOL has become a relevant measure of efficacy of treatme...Quality of Life (QOL) is a multiphase conception, including physical, mental and social factors, and can overall reflect health status of the human. At present, QOL has become a relevant measure of efficacy of treatment in clinical trials. Its use is spreading, and its importance is growing as a valid indicator of whether or not a medical treatment is展开更多
BACKGROUND Little is known about health status and quality of life(QoL)after implantable cardioverter-defibrillator(ICD)generator exchange(GE).METHODS We prospectively followed patients undergoing first-time ICD GE.Se...BACKGROUND Little is known about health status and quality of life(QoL)after implantable cardioverter-defibrillator(ICD)generator exchange(GE).METHODS We prospectively followed patients undergoing first-time ICD GE.Serial assessments of health status were performed by administering the 36-Item Short Form Survey(SF-36).RESULTS Mean age was 67.5±14.3 years,left ventricle ejection fraction(LVEF)was 36.5%±15.0%and over 40%of the cohort had improved LVEF to>35%at the time of GE.SF-36 scores were significantly worse in physical/general health domains compared to domains of emotional/social well-being(P<0.001 for each comparison).Physical health scores were significantly worse among those with medical comorbidities including diabetes,chronic obstructive pulmonary disease and atrial fibrillation.Mean follow-up was 1.6±0.5 years after GE.Overall SF-36 scores remained stable across all domains during follow-up.Survival at 3 years post-GE was estimated at 80%.Five patients died during follow-up and most deaths were adjudicated as non-arrhythmic in origin.Four patients experienced appropriate ICD shocks after GE,three of whom had LVEF which remains impaired LVEF(i.e.,<35%)at the time of GE.CONCLUSION Patients undergoing ICD GE have significantly worse physical health compared to emotional/social well-being,which is associated with the presence of medical comorbidities.In terms of clinical outcomes,the incidence of appropriate shocks after GE among those with improvement in LVEF is very low,and most deaths post-procedure appear to be non-arrhythmic in origin.These data represent an attempt to more fully characterize the spectrum of QoL and clinical outcomes after GE.展开更多
Introduction: Nigeria accounts for 150,000 infants born with the Sickle Cell Disease (SCD) every year. Children with SCD are affected by the deleterious effect of user fees which reduces affordability and utilization ...Introduction: Nigeria accounts for 150,000 infants born with the Sickle Cell Disease (SCD) every year. Children with SCD are affected by the deleterious effect of user fees which reduces affordability and utilization of health services. Evidences supported that institutionalized health insurance increases intensity of utilization. Methodology: The study was conducted at AKTH, Kano, and north-western, Nigeria. The study was retrospective comparative cross-sectional study. 100 patients were enrolled, 50 for each arm. Paediatric SCD clinic outpatients’ records and a specialty designed form containing the variables of interest were used. Data were analysed using Minitab 16. Proportions, percentages, tables, charts and chi squared test were used to compare the two groups. Result: The study found no association between the two groups in the likelihood of being insured based on age (χ<sup>2</sup> = 1.478), gender (χ<sup>2</sup> = 0.224) and dwellings (χ<sup>2</sup> = 0.062). On health services utilization and insurance status, the study revealed that follow up clinic visits, unscheduled clinic visits and emergency room visits were more likely among the insured group compared to the uninsured group. While the health status and insurance status of the two groups over 12 months period showed a significant association with the insured more likely to have improved health status compared to uninsured (χ<sup>2</sup> = 28.019, p = 0.0001). Similarly, health status and health services utilization were significantly associated with insurance status (χ<sup>2</sup> = 12.191, p = 0.002). Conclusion: The insurance status of children with SCD is associated with their health services utilization and health status. However, age, gender and dwellings were not associated with insurance status of children with SCD. Therefore, when expanding insurance coverage (NHIS) among children with SCD considerations have to be given to increase health services utilization and resultant improvement in health status as these have the potential of reducing morbidity and mortality among children with SCD.展开更多
We investigated associations between smartphone dependence and general health status or personality traits. To 197 medical university students, we administered a set of self-reporting questionnaires designed to evalua...We investigated associations between smartphone dependence and general health status or personality traits. To 197 medical university students, we administered a set of self-reporting questionnaires designed to evaluate these parameters. For males, smartphone dependence positively correlated with somatic symptoms, anxiety and insomnia, and emotional instability, and negatively correlated with agreeableness. For females, smartphone dependence positively correlated with somatic symptoms, severe depression, and extraversion, and negatively correlated with social dysfunction. These findings suggest that smartphone dependence may be associated with general health status or personality traits and that there may be a gender difference in these associations.展开更多
Health care facilities are a high-risk environment for generating and spreading respiratory infectious diseases such as tuberculosis (TB). The TB prevention and treatment staff in health care facilities are responsi...Health care facilities are a high-risk environment for generating and spreading respiratory infectious diseases such as tuberculosis (TB). The TB prevention and treatment staff in health care facilities are responsible for the identification, diagnosis, treatment, supervision, and management of TB patients .展开更多
BACKGROUND Lung resection represents the main curative treatment modality of non-small cell lung cancer.Patients with high-risk to develop postoperative pulmonary complications have been classified as“high-risk patie...BACKGROUND Lung resection represents the main curative treatment modality of non-small cell lung cancer.Patients with high-risk to develop postoperative pulmonary complications have been classified as“high-risk patients.”Characterizing this population could be important to improve their approach and rehabilitation.AIM To identify the differences between high and low-risk patients in exercise capacity and self-perceived health status after hospitalization.METHODS A longitudinal observational prospective cohort study was carried out.Patients undergoing lung resection were recruited from the“Hospital Virgen de las Nieves”(Granada)and divided into two groups according to the risk profile criteria(age≥70 years,forced expiratory volume in 1 s≤70%predicted,carbon monoxide diffusion capacity≤70%predicted or scheduled pneumonectomy).Outcomes included were exercise capacity(Fatigue Severity Scale,Unsupported Upper-Limb Exercise,handgrip dynamometry,Five Sit-to-stand test,and quadriceps hand-held dynamometry)and patient-reported outcome(Euroqol-5 dimensions 5 Levels Visual Analogue Scale).RESULTS In total,115 participants were included in the study and divided into three groups:high-risk,low-risk and control group.At discharge high-risk patients presented a poorer exercise capacity and a worse self-perceived health status(P<0.05).One month after discharge patients in the high-risk group maintained these differences compared to the other groups.CONCLUSION Our results show a poorer recovery in high-risk patients at discharge and 1 mo after surgery,with lower self-perceived health status and a poorer upper and lower limb exercise capacity.These results are important in the rehabilitation field.展开更多
Few studies investigated the effects of exposure to NO_(2) on health status in the Chinese floating population.The present cross-sectional study evaluated the association of ambient NO_(2) with health status in a floa...Few studies investigated the effects of exposure to NO_(2) on health status in the Chinese floating population.The present cross-sectional study evaluated the association of ambient NO_(2) with health status in a floating population in China.Data on 168961 floating individuals in 338 cities were obtained from the 2017 China Migrants Dynamic Survey.The association between exposure to NO_(2) and self-related health(SRH)status was assessed by binary logistic regression analysis,both in the entire subject cohort and in subgroups assorted by socioeconomic levels and demographic characteristics.The robustness of the associations between NO_(2) exposure and health status was evaluated by sensitivity analyses.Each grade increment of annual average NO_(2) exposure was found to increase the risk of poor SRH by 2.4%in the floating population(odds ratio[OR]=1.024,95%confidence interval[CI]:1.011-1.038).When subgrouped by age,subjects in the floating population aged 31-49 years had the highest NO_(2) associated health risk(OR=1.036,95%CI:1.018-1.054).When subgrouped by per capita gross domestic product(PGDP),subjects in regions with mid-level PDGP had the highest NO_(2) associated SRH(OR=1.116,95%CI:1.091-1.i41).These findings indicated that exposure to NO_(2) increases the risk of poor SRH in the floating population,with individuals aged 31-49 years and those living in mid-level PGDP regions being more sensitive to the adverse effects of NO_(2).More effective strategies to reduce air pollution may improve the health status of the floatingpopulation in China.展开更多
The study aimed to assess the effects of dietary black soldier fly oil(BSFO)on the growth performance,flesh quality,and health status of largemouth bass(Micropterus salmoides).Six iso-nitrogenous and isolipid diets we...The study aimed to assess the effects of dietary black soldier fly oil(BSFO)on the growth performance,flesh quality,and health status of largemouth bass(Micropterus salmoides).Six iso-nitrogenous and isolipid diets were formulated by substituting fish oil and soybean oil(1/2,wt/wt)with BSFO in percentages of 0%,20%,40%,60%,80%,and 100%,respectively.The diets were fed to 960 fish(initial body weight=16.5 g)in four replicates for 8 weeks.Indicators related to growth performance,body composition,hematology,flesh quality,expression of genes related to inflammatory cytokines and apoptosis,and the response of fish to Aeromonas veronii challenge were analyzed.The results showed that the weight gain rate was numerically improved in all BSFO substitution groups,ranging from 9.3%to 44.0%compared to the control group.The highest survival rate and the lowest hepatosomatic index and condition factor were observed in the BFSO20 group.In terms of flesh quality,the water-holding capacity of the dorsal muscle was elevated with higher levels of dietary BSFO.However,significant changes in texture properties(cohesiveness,gluing,and chewiness)were observed in the BSFO20 group(P<0.05).Six hematological parameters related to glycolipid and liver function were optimized in most of the BFSO substitution groups.Furthermore,the expressions of six inflammation-and apoptosis-related genes(IL-1β,Bcl-xl,BAX,caspase8,TNF-α,and IL-10)were significantly affected by dietary BSFO(P<0.05).Following bacterial challenge,the seven-day cumulative survival rates of fish were considerably increased from 10.0%in the control group to 60.0%and 66.7%in the BSFO80 and BSFO100 groups,respectively.One-variable linear regression analysis revealed that various parameters related to fish growth,flesh quality,and health status were significantly influenced by dietary BSFO substitution levels in a dose-dependent manner(P<0.05).In conclusion,substituting around 20%of dietary fish oil and soybean oil with BSFO is promising in improving the growth performance and flesh quality of M.salmoides.However,to enhance immunity and disease resistance,it is recommended to further increase the inclusion of BSFO in the diet.展开更多
The present study sampled the intestinal content of healthy and unhealthy Atlantic salmon (Salmo salar L.), the ambient water of unhealthy fish, and the biofilter material in the recirculating aquaculture system (...The present study sampled the intestinal content of healthy and unhealthy Atlantic salmon (Salmo salar L.), the ambient water of unhealthy fish, and the biofilter material in the recirculating aquaculture system (RAS) to understand differences in the intestinal microbiota. The V4--V5 regions of the prokaryotic 16S rRNA genes in the samples were analyzed by MiSeq high-throughput sequencing. The fish were adults with no differences in body length or weight. Representative members of the intestinal microbiota were identified. The intestinal microbiota of the healthy fish included Proteobacteria (44.33%), Actinobacteria (17.89%), Baeteroidetes (15.25%), and Firmicutes (9.11%), among which the families Mierococcaceae and Oxalobacteraceae and genera Sphingomonas, Streptomyces, Pedobacter, Janthinobacterium, Burkholderia, and Balneimonas were most abundant. Proteobacteria (70.46%), Bacteroidetes (7.59%), and Firmicutes (7.55%) dominated the microbiota of unhealthy fish, and Chloroflexi (2.71%), and Aliivibrio and Vibrio as well as genera in the family Aeromonadaceae were most strongly represented. Overall, the intestinal hindgut microbiota differed between healthy and unhealthy fish. This study offers a useful tool for monitoring the health status of fish and for screening the utility of probiotics by studying the intestinal microbiota.展开更多
The main purpose of the National Nutrition and Health Systematic Survey for children 0-17 years of age in China(CNHSC)was to collect basic data on the nutrition,development,and health status for children in different ...The main purpose of the National Nutrition and Health Systematic Survey for children 0-17 years of age in China(CNHSC)was to collect basic data on the nutrition,development,and health status for children in different regions across China using evidence-based,reliable,and cost-effective approaches.Children and their parents or guardians from seven regions(south,southwest,north,northwest,eastern,central,and northeast China)in China were recruited.A multi-stage stratified randomized sampling method was used.Two provinces were randomly sampled from each of the seven regions,from which one urban district and one rural country were also randomly sampled,resulting in a total of 28 survey counties/districts.Dietary surveys,health examinations,laboratory testing,and questionnaires were used to collect dietary intake,nutritional status,child development,and health status information.Nutrition,health,and lifestyle assessment of children and their parents was determined using the Knowledge Attitude Practice(KAP)survey.Greater than 100,000 children(38,000 children<6 years of age and 66,000 children6-17 years of age)completed the survey.The survey provided comprehensive data on child nutrition and health status for future studies and will serve as the basis for an integrated nutrition and health improvement strategies proposal for children in China.展开更多
文摘Objective:The study aimed to assess medication management compliance and mental health in elderly patients with hypertension.Method:The study evaluated medication compliance and mental health status of elderly hypertensive patients in China using simple random sampling.Data was collected using the Morisky Medication Compliance Questionnaire,Hospital Anxiety and Depression Scale,and a checklist.Ethical practices were strictly observed.Results:A study of 100 elderly hypertensive patients found poor drug management compliance,with female patients showing worse compliance.Female patients were more vulnerable to anxiety and depression.The study also found no significant association between gender,age,education level,marital status,living standards,and medication compliance.Barriers to medication management included food and daily necessities,lack of awareness about the importance of drug treatment,and basic family needs.The lowest-ranked barriers were lack of support from government health clinics,low income,and lack of family support.Conclusion:Based on the results,the study proposes an educational plan for elderly hypertensive patients and their families,to be evaluated and implemented by the hospital and township community service center.The plan aims to improve medication management and lifestyle modification compliance,encourage active participation,and provide access to medical and mental health clinics,support groups,and counseling services.
基金the National Nature Science Foundation(Grant Number:31930101).
文摘Background Rises in global warming and extreme weather occurrence make the risk of heat stress(HS)induced by high ambient temperatures more likely in high-yielding dairy cows,resulting in low milk quality and yield.In ani-mals,oxygen is involved in many physiological and metabolic processes,but the effects of HS on oxygen metabolism remain unclear.Thus,the current study aimed to investigate how oxygen metabolism plays a role in health status of dairy cows by measuring the milk yield,milk composition,and blood biochemical variables of cows under different levels of HS:none(No-HS),mild(Mild-HS),and moderate HS(Mod-HS).Results The HS significantly increased rectal temperature(Ptreat<0.01)and respiration rate(Ptreat<0.01).Under Mod-HS,greater Na+(P<0.05)and lower total CO_(2),and pH(P<0.05)were observed relative to those under No-HS and Mild-HS.Oxygen concentrations in both coccygeal artery and mammary vein(Ptreat<0.01)were lower under Mod-HS than under No-HS.Coccygeal vein concentrations of heat shock protein 90(HSP90)(P<0.05)increased during Mod-HS compared with those in cows under No-HS.Malondialdehyde increased during Mod-HS,and glu-tathione peroxidase(P<0.01)increased during Mild-HS.Coccygeal vein concentrations of vascular endothelial growth factor(P<0.01),heme oxygenase-1(P<0.01),and hypoxia-inducible factor 1α(P<0.01)were greater in cows under Mod-HS than those under No-HS.Red blood cell count(P<0.01)and hemoglobin concentration(P<0.01)were lower in the coccygeal vein of dairy cows under Mild-and Mod-HS than those of cows under No-HS.Conclusions Exposure to HS negatively impacts the health status and lactation performance of dairy cows by limit-ing oxygen metabolism and transportation.However,the specific mechanism by which HS affects mammary function in cows remains unclear and requires further exploration.
文摘Dietary factors play an important role in human health. Specifically, nutritional interventions may have an impact on the hypothalamic-pituitary axis resulting in positive health outcomes. A retrospective health status survey of 386 respondents was conducted to investigate the potential of a dietary supplement, Nutrifii<sup>TM</sup> Renew, for improving various health outcomes in comparison to a multivitamin/mineral control group. Among those who ingested Renew, 95% reported experiencing at least some improvement in one or more health categories. Compared to the multivitamin/mineral group, the Renew group reported earlier and/or greater improvements in several health status categories including sleep, reproductive health, memory, energy/stamina, skin and hair quality, flexibility, exercise recovery and feeling rested in the morning. A clear majority (84.9%) of Renew consumers reported experiencing noticeable improvement in some aspect of their health within one month. Among those who felt an improvement in sleep, most reported experiencing a change within one week. These improvements were likely due to the synergistic effects of L-arginine, L-citrulline, L-lysine, and botanical extracts on nitric oxide production, growth hormone (GH) release, and sleep quality. The observed improvements in skin elasticity and hair growth may be related to increased GH levels and IGF-1 production. Overall, these findings suggest that Renew may have potential as a dietary intervention for improving various health outcomes beyond those provided by multivitamin/mineral supplementation alone. Further studies are needed to confirm these findings and elucidate the underlying mechanisms of action.
文摘Background: The COVID-19 epidemic is a public health security event affecting the whole country, which has a certain impact on the development and current situation of the health field. As a special group, children and adolescents need to receive attention and special care. Purpose: To study the health status of children and adolescents under the influence of COVID-19. Method: To collect and analyze the physical, mental and mental health data of 448 children aged 3 - 18 years in the Pediatric Medical Center of the Second Hospital of Jilin University since the COVID-19 outbreak, so as to grasp the physical, mental and mental health status and existing problems of children and adolescents under the impact of COVID-19 outbreak. Results: Food (seafood, mangoes, dairy products, animal protein, soy, peanuts, etc.) is the main allergen in the children and adolescents who participated in the survey, followed by inhalation (pollen, cat and dog hair, etc.). The diet was relatively normal, but there were still unhealthy eating behaviors, the detection rate was 5.36%. High calorie diet, high cholesterol diet, high salt diet, low protein diet, liquid diet in order from high to low, 85.27% of the normal water intake, drinking behavior was greatly affected by the family environment and school environment. The main problem affecting children’s digestion is constipation. Functional constipation accounts for more than 90% of children’s constipation, and its causes are mainly genetic factors, metabolic factors, mental factors, diet factors, etc. Genetic factors and unreasonable diet are the causes of children’s research results show that among 448 children and adolescents, 425 are in normal mental conditions. 94.87%;13, or 2.9%, were in the doldrums;There were 10 people in the state of hyperactivity, accounting for 2.23%, the main cause of functional. Conclusion: The health cloud platform was used to manage and analyze the data, in order to lay the foundation for the healthy growth and development of children and adolescents as well as the whole life cycle management of individual health.
文摘The health status of the floating elderly population and the need of community management services are complex and important problems.Owing to the change of living environment and the insecure medical care,the mobile elderly people have more health and psy-chological problems compared to the rest of the elderly population.Therefore,the community should take a variety of measures to meet their needs and help them to better adapt to the new living environment,and maintain their physical and mental health.This paper aims to summarize recent studies on the physical and emotional health problems of mobile elderly people and related community management service needs.
基金funded by a grant from Scientific Research in the Public Interest(201502002)conducted by the Department of Preventive Dentistry,West China Hospital of Stomatology,Sichuan University,China
文摘To investigate oral health status in the residents of Sichuan Province, southwest China, a cross-sectional study was performed using the latest Oral Health Survey Basic Methods recommended by the World Health Organization. A multistage stratified random cluster-sampling method was used to enroll participants from the following three groups: children aged 3-5 years, adolescents aged 12 years, and people aged 65-74 years. In these three groups, the mean numbers of teeth that were affected by caries were 3.28, 0.86 and 5.13, respectively, resulting in a prevalence of 63.47%, 37.20% and 83.20%, respectively. Relative to the high rate of decayed teeth, the prevalence of fillings was very low in all age groups (0.97%, 7.24% and 5.43%, respectively), In the 12-year-old adolescent group, only 3.61% had good pit and fissure sealing. In addition, the rate of dental fluorosis was 24.80%, and the Community Fluorosis Index value was 0.39. In the elder group, the community periodontal index was 2.92. The prevalence in the elderly of having lost at least one tooth was 75.54%. Additionally, 4.44% of these participants were edentulous. The incidence of dental prosthesis was 51.75%, the proportion with a removable partial denture, a fixed denture, full dentures, dental implants and an informal fixed bridge was 21.59%, 11.45%, 4.64%, 0 and 16.67%, respectively. In this study, 8.2% of the elderly participants were affected by different types of oral mucosal lesions. Among such lesions, recurrent aphthous ulcers were most prevalent (2.69%) and oral lichen planuses were second (1.6%). The conclusion presented in this survey is that oral diseases, especially dental caries and periodontal disease, are frequent and common in Sichuan province, China. Moreover, the treatment rate is very low, and primary prevention and treatment options are therefore urgently needed in this population.
文摘Objectives:To describe the characteristics and relationships of social isolation and health promoting behaviors of Chinese older adults with different health statuses.Methods:Totally 485 older adults were recruited.They were divided into three groups based on their health status:healthy group(n=72),group with one disease(n=183)and group with multimorbidity(n=230).Lubben Social Network Scale-6 and Health-Promoting Lifestyle Profile II were used to measure their social isolation and health-promoting behaviors,respectively.Results:Among the aged with one disease or multimorbidity,30.6%(56/183)and 31.7%(73/230)were socially isolated,respectively,based on the score of the Lubben Social Network Scale-6.The three groups differed significantly in health-promoting behaviors and scores on several subscales.The group with multimorbidity exhibited more social isolation and fewer health-promoting behaviors than other groups.Social isolation was among the factors adversely affecting health-promoting behaviors in older adults.Conclusions:Health care providers should help older adults with multimorbidity preserve the remaining abilities to improve health-promoting behaviors.Meanwhile,it is important to support healthy older adults to increase self-responsibility to achieve healthy aging.
基金Supported by the National Key Research and Development Program of China(No.2019YFB2005204)the National Natural Science Foundation of China(No.52075469,51675461,11673040)+1 种基金the Key Research and Development Program of Hebei Province(No.19273708D)the Open Foundation of the State Key Laboratory of Fluid Power and Mechatronic Systems(No.GZKF-201922).
文摘The axial piston pump usually works under variable speed conditions.It is important to evaluate the health status of the axial piston pump under the variable speed condition.Aiming at the characteristic signals obtained under different wear levels of the port plate,a feature signal extraction method under variable speed conditions is proposed.Firstly,the combination of complete ensemble empirical mode decomposition with adaptive noise(CEEMDAN)energy spectrum and fast spectral kurtosis principle is used to accurately extract the intrinsic mode function(IMF)component containing the sensitive information of the degraded feature.Then,the aspect ratio analysis method of the angle domain variational mode decomposition(VMD)is used to process the feature index containing the sensitive information of the degraded feature.In order to evaluate the health status of the axial piston pump under variable speed,the vibration reliability analysis method for axial piston pump based on Weibull proportional failure rate model is proposed.The experimental results show that the proposed method can accurately evaluate the health status of the axial piston pump.
文摘Schools and parents should pay attention to health education for students' health awareness and good health habits, to establish a correct concept of health. School mental health education should be the first place; school should create a positive learning environment for students to get knowledge and skills of exercising. Especially in the nine years of compulsory education stage, we should ensure necessary physical exercise, reasonable arrangements for extracurricular activities to improve students' physical fitness. We should improve the school' s sports facilities, and create a good campus atmosphere. Schools should actively carry out extra-curricular sports activities, improve the level of quality of physical education teachers, develop students' sports consciousness, and improve material conditions for the students to create a good learning environment, meanwhile, we should increase the content of education, and enrich the content of physical education to enable students to select and reach more sports.
文摘Background: The Tubu are nomadic people who live in remote parts of the central Sahara, primarily in the Tibesti massif(Chad), and in both Northeastern Niger and Southern Libya. All of these areas are close to become conflict zones. However, no data about the Tubu's health and sanitary status are currently available, which would be of major concern if humanitarian interventions would become required.Methods: In 1970, the "Mission Anthropologique Belge au Niger"(MABN) investigated a Tubu tribe named Broaya that lived at Seguedine and Djado on the northeastern rim of the Tenere desert. One hundred fifty-one adult volunteers answered an oral questionnaire and underwent a medical examination, followed by the collection of blood thin films and samples of urine and stool. The environmental fauna of medical importance was also studied.Results: Albeit 43 year-old, these results have not been previously published. The estimated age of death for fathers was approximately 56 years, and that for mothers was 60 years. On average, each married woman had had 4.7 children. The overall perinatal mortality rate was 232 ‰, the overall infant mortality rate was 153 ‰, and the overall child mortality rate was 99 ‰. The mean height was 164.1 cm and 157.4 cm, the mean weight was 50.1 kg and 47.9kg, and the mean blood pressure was 131/78 mm Hg and 127/75 mm Hg for males and females, respectively. The physical examination found 6 cases of blindness(4.0%). Five subjects presented with an elevated blood pressure(3.3%), and 5(3.3%) displayed an abnormal thoracic auscultation evocative of tuberculosis or of an acute lung infection. The abdominal examination and renal palpation found 5 large masses(3.3%), and 2 subjects had a palpable enlarged spleen(1.3%). The blood thin films were fixed in methanol and subsequently examined in Toulouse. The search for blood parasites was negative. The urine samples were centrifuged and then microscopically examined in the field. No blood-fluke eggs were found. The stool samples were mixed with a preservative MIF solution and then stored to be examined later in Toulouse. Three subjects(2%) passed E. histolytica/E. dispar cysts in stools, 16(10.6%) were parasitized with Giardia sp. and 4(2.65%) were parasitized with Hymelepis nana. Two specimens of scorpions captured in the camp were subsequently identified as belonging to the harmful genus Androctonus or Leiurus. An investigation into the freshwater fauna was conducted in the marshy ponds surrounding the ghost city of Djado, and no intermediate snail hosts for schistosomiasis haematobium were found. Numerous nymphs of Ceratopogonidae, which are possible vectors for arboviruses of veterinarian importance, were collected, as were larvae and nymphs from two anopheline species, Anopheles hispaniola and An. multicolor, which are not efficient vectors for malaria.Conclusions: Infection-related blindness and trachoma, along with acute pulmonary infections and probably tuberculosis were the major health burden in this tribe. The harsh dry and hot climate may explain the low prevalence of soil-transmitted protozoan diseases or helminthiases.
文摘Quality of Life (QOL) is a multiphase conception, including physical, mental and social factors, and can overall reflect health status of the human. At present, QOL has become a relevant measure of efficacy of treatment in clinical trials. Its use is spreading, and its importance is growing as a valid indicator of whether or not a medical treatment is
基金supported by a Pilot Translational&Clinical Studies Program grant from the National Center for Advancing Translational Studies of the National Institutes of Health(UL1TR002378)a FAME grant from the Emory University Department of Medicine。
文摘BACKGROUND Little is known about health status and quality of life(QoL)after implantable cardioverter-defibrillator(ICD)generator exchange(GE).METHODS We prospectively followed patients undergoing first-time ICD GE.Serial assessments of health status were performed by administering the 36-Item Short Form Survey(SF-36).RESULTS Mean age was 67.5±14.3 years,left ventricle ejection fraction(LVEF)was 36.5%±15.0%and over 40%of the cohort had improved LVEF to>35%at the time of GE.SF-36 scores were significantly worse in physical/general health domains compared to domains of emotional/social well-being(P<0.001 for each comparison).Physical health scores were significantly worse among those with medical comorbidities including diabetes,chronic obstructive pulmonary disease and atrial fibrillation.Mean follow-up was 1.6±0.5 years after GE.Overall SF-36 scores remained stable across all domains during follow-up.Survival at 3 years post-GE was estimated at 80%.Five patients died during follow-up and most deaths were adjudicated as non-arrhythmic in origin.Four patients experienced appropriate ICD shocks after GE,three of whom had LVEF which remains impaired LVEF(i.e.,<35%)at the time of GE.CONCLUSION Patients undergoing ICD GE have significantly worse physical health compared to emotional/social well-being,which is associated with the presence of medical comorbidities.In terms of clinical outcomes,the incidence of appropriate shocks after GE among those with improvement in LVEF is very low,and most deaths post-procedure appear to be non-arrhythmic in origin.These data represent an attempt to more fully characterize the spectrum of QoL and clinical outcomes after GE.
文摘Introduction: Nigeria accounts for 150,000 infants born with the Sickle Cell Disease (SCD) every year. Children with SCD are affected by the deleterious effect of user fees which reduces affordability and utilization of health services. Evidences supported that institutionalized health insurance increases intensity of utilization. Methodology: The study was conducted at AKTH, Kano, and north-western, Nigeria. The study was retrospective comparative cross-sectional study. 100 patients were enrolled, 50 for each arm. Paediatric SCD clinic outpatients’ records and a specialty designed form containing the variables of interest were used. Data were analysed using Minitab 16. Proportions, percentages, tables, charts and chi squared test were used to compare the two groups. Result: The study found no association between the two groups in the likelihood of being insured based on age (χ<sup>2</sup> = 1.478), gender (χ<sup>2</sup> = 0.224) and dwellings (χ<sup>2</sup> = 0.062). On health services utilization and insurance status, the study revealed that follow up clinic visits, unscheduled clinic visits and emergency room visits were more likely among the insured group compared to the uninsured group. While the health status and insurance status of the two groups over 12 months period showed a significant association with the insured more likely to have improved health status compared to uninsured (χ<sup>2</sup> = 28.019, p = 0.0001). Similarly, health status and health services utilization were significantly associated with insurance status (χ<sup>2</sup> = 12.191, p = 0.002). Conclusion: The insurance status of children with SCD is associated with their health services utilization and health status. However, age, gender and dwellings were not associated with insurance status of children with SCD. Therefore, when expanding insurance coverage (NHIS) among children with SCD considerations have to be given to increase health services utilization and resultant improvement in health status as these have the potential of reducing morbidity and mortality among children with SCD.
文摘We investigated associations between smartphone dependence and general health status or personality traits. To 197 medical university students, we administered a set of self-reporting questionnaires designed to evaluate these parameters. For males, smartphone dependence positively correlated with somatic symptoms, anxiety and insomnia, and emotional instability, and negatively correlated with agreeableness. For females, smartphone dependence positively correlated with somatic symptoms, severe depression, and extraversion, and negatively correlated with social dysfunction. These findings suggest that smartphone dependence may be associated with general health status or personality traits and that there may be a gender difference in these associations.
基金funded by the China-Gates Foundation TB Control Project(Phase Ⅱ)(51914)
文摘Health care facilities are a high-risk environment for generating and spreading respiratory infectious diseases such as tuberculosis (TB). The TB prevention and treatment staff in health care facilities are responsible for the identification, diagnosis, treatment, supervision, and management of TB patients .
文摘BACKGROUND Lung resection represents the main curative treatment modality of non-small cell lung cancer.Patients with high-risk to develop postoperative pulmonary complications have been classified as“high-risk patients.”Characterizing this population could be important to improve their approach and rehabilitation.AIM To identify the differences between high and low-risk patients in exercise capacity and self-perceived health status after hospitalization.METHODS A longitudinal observational prospective cohort study was carried out.Patients undergoing lung resection were recruited from the“Hospital Virgen de las Nieves”(Granada)and divided into two groups according to the risk profile criteria(age≥70 years,forced expiratory volume in 1 s≤70%predicted,carbon monoxide diffusion capacity≤70%predicted or scheduled pneumonectomy).Outcomes included were exercise capacity(Fatigue Severity Scale,Unsupported Upper-Limb Exercise,handgrip dynamometry,Five Sit-to-stand test,and quadriceps hand-held dynamometry)and patient-reported outcome(Euroqol-5 dimensions 5 Levels Visual Analogue Scale).RESULTS In total,115 participants were included in the study and divided into three groups:high-risk,low-risk and control group.At discharge high-risk patients presented a poorer exercise capacity and a worse self-perceived health status(P<0.05).One month after discharge patients in the high-risk group maintained these differences compared to the other groups.CONCLUSION Our results show a poorer recovery in high-risk patients at discharge and 1 mo after surgery,with lower self-perceived health status and a poorer upper and lower limb exercise capacity.These results are important in the rehabilitation field.
基金supported by the National Natural Science Foundation of China(No.72374033)the Social Science Planning Research Project of Shandong Province(China)(No.22CRKJ01).
文摘Few studies investigated the effects of exposure to NO_(2) on health status in the Chinese floating population.The present cross-sectional study evaluated the association of ambient NO_(2) with health status in a floating population in China.Data on 168961 floating individuals in 338 cities were obtained from the 2017 China Migrants Dynamic Survey.The association between exposure to NO_(2) and self-related health(SRH)status was assessed by binary logistic regression analysis,both in the entire subject cohort and in subgroups assorted by socioeconomic levels and demographic characteristics.The robustness of the associations between NO_(2) exposure and health status was evaluated by sensitivity analyses.Each grade increment of annual average NO_(2) exposure was found to increase the risk of poor SRH by 2.4%in the floating population(odds ratio[OR]=1.024,95%confidence interval[CI]:1.011-1.038).When subgrouped by age,subjects in the floating population aged 31-49 years had the highest NO_(2) associated health risk(OR=1.036,95%CI:1.018-1.054).When subgrouped by per capita gross domestic product(PGDP),subjects in regions with mid-level PDGP had the highest NO_(2) associated SRH(OR=1.116,95%CI:1.091-1.i41).These findings indicated that exposure to NO_(2) increases the risk of poor SRH in the floating population,with individuals aged 31-49 years and those living in mid-level PGDP regions being more sensitive to the adverse effects of NO_(2).More effective strategies to reduce air pollution may improve the health status of the floatingpopulation in China.
基金supported by Key project of Research and Development Programme of Guangdong Province (2021B0202050002)Project of Guangdong Province Guiding Local Science and Technology Devel opment (GS202331)d Open Project of Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition Research (2022SZ05).
文摘The study aimed to assess the effects of dietary black soldier fly oil(BSFO)on the growth performance,flesh quality,and health status of largemouth bass(Micropterus salmoides).Six iso-nitrogenous and isolipid diets were formulated by substituting fish oil and soybean oil(1/2,wt/wt)with BSFO in percentages of 0%,20%,40%,60%,80%,and 100%,respectively.The diets were fed to 960 fish(initial body weight=16.5 g)in four replicates for 8 weeks.Indicators related to growth performance,body composition,hematology,flesh quality,expression of genes related to inflammatory cytokines and apoptosis,and the response of fish to Aeromonas veronii challenge were analyzed.The results showed that the weight gain rate was numerically improved in all BSFO substitution groups,ranging from 9.3%to 44.0%compared to the control group.The highest survival rate and the lowest hepatosomatic index and condition factor were observed in the BFSO20 group.In terms of flesh quality,the water-holding capacity of the dorsal muscle was elevated with higher levels of dietary BSFO.However,significant changes in texture properties(cohesiveness,gluing,and chewiness)were observed in the BSFO20 group(P<0.05).Six hematological parameters related to glycolipid and liver function were optimized in most of the BFSO substitution groups.Furthermore,the expressions of six inflammation-and apoptosis-related genes(IL-1β,Bcl-xl,BAX,caspase8,TNF-α,and IL-10)were significantly affected by dietary BSFO(P<0.05).Following bacterial challenge,the seven-day cumulative survival rates of fish were considerably increased from 10.0%in the control group to 60.0%and 66.7%in the BSFO80 and BSFO100 groups,respectively.One-variable linear regression analysis revealed that various parameters related to fish growth,flesh quality,and health status were significantly influenced by dietary BSFO substitution levels in a dose-dependent manner(P<0.05).In conclusion,substituting around 20%of dietary fish oil and soybean oil with BSFO is promising in improving the growth performance and flesh quality of M.salmoides.However,to enhance immunity and disease resistance,it is recommended to further increase the inclusion of BSFO in the diet.
基金Supported by the National Natural Science Foundation of China(Nos.31472312,41306152,31402283)the Qingdao Innovation Talents Program(No.13-CX-16)+2 种基金the National Key Technology Research and Development Program of China(No.2014BAD08B09)the Earmarked Fund for Modern Agroindustry Technology Research System(No.CARS-48)the Project for International S&T Cooperation Program of China(No.2014DFA31030)
文摘The present study sampled the intestinal content of healthy and unhealthy Atlantic salmon (Salmo salar L.), the ambient water of unhealthy fish, and the biofilter material in the recirculating aquaculture system (RAS) to understand differences in the intestinal microbiota. The V4--V5 regions of the prokaryotic 16S rRNA genes in the samples were analyzed by MiSeq high-throughput sequencing. The fish were adults with no differences in body length or weight. Representative members of the intestinal microbiota were identified. The intestinal microbiota of the healthy fish included Proteobacteria (44.33%), Actinobacteria (17.89%), Baeteroidetes (15.25%), and Firmicutes (9.11%), among which the families Mierococcaceae and Oxalobacteraceae and genera Sphingomonas, Streptomyces, Pedobacter, Janthinobacterium, Burkholderia, and Balneimonas were most abundant. Proteobacteria (70.46%), Bacteroidetes (7.59%), and Firmicutes (7.55%) dominated the microbiota of unhealthy fish, and Chloroflexi (2.71%), and Aliivibrio and Vibrio as well as genera in the family Aeromonadaceae were most strongly represented. Overall, the intestinal hindgut microbiota differed between healthy and unhealthy fish. This study offers a useful tool for monitoring the health status of fish and for screening the utility of probiotics by studying the intestinal microbiota.
基金supported by the National Special Program for Science&Technology Basic Resources Investigation of China[Grant No.2017FY101100,2017FY101101,2017FY101102,2017FY101103,2017FY101104,2017FY101105,2017FY101106,and 2017FY101107]。
文摘The main purpose of the National Nutrition and Health Systematic Survey for children 0-17 years of age in China(CNHSC)was to collect basic data on the nutrition,development,and health status for children in different regions across China using evidence-based,reliable,and cost-effective approaches.Children and their parents or guardians from seven regions(south,southwest,north,northwest,eastern,central,and northeast China)in China were recruited.A multi-stage stratified randomized sampling method was used.Two provinces were randomly sampled from each of the seven regions,from which one urban district and one rural country were also randomly sampled,resulting in a total of 28 survey counties/districts.Dietary surveys,health examinations,laboratory testing,and questionnaires were used to collect dietary intake,nutritional status,child development,and health status information.Nutrition,health,and lifestyle assessment of children and their parents was determined using the Knowledge Attitude Practice(KAP)survey.Greater than 100,000 children(38,000 children<6 years of age and 66,000 children6-17 years of age)completed the survey.The survey provided comprehensive data on child nutrition and health status for future studies and will serve as the basis for an integrated nutrition and health improvement strategies proposal for children in China.