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Comprehensive effects of traditional Chinese medicine treatment on heart failure and changes in B-type natriuretic peptide levels: A meta-analysis
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作者 Li-Li Xia Shu-Yun Yang +2 位作者 Jun-Yao Xu Han-Qing Chen Zhu-Yuan Fang 《World Journal of Clinical Cases》 SCIE 2024年第4期766-776,共11页
BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,... BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious. 展开更多
关键词 Traditional Chinese medicine heart failure Comprehensive clinical outcomes Traditional Chinese medicine syndrome score B-type natriuretic peptide level Meta-analysis©The Author(s)2024.Published by Baishideng Publishing Group Inc.
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经皮二氧化碳分压监测在硬质支气管镜下Feng′s EBUS-TBNB中的应用
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作者 骆玉兔 孙亚楠 +1 位作者 潘家华 万南生 《南通大学学报(医学版)》 2024年第1期45-48,共4页
目的:探讨经皮二氧化碳分压(transcutaneous partial pressure of carbon dioxide,PtcCO_(2))监测在硬质支气管镜下冯氏气管内超声引导纵隔切开活检(Feng′s endobronchial ultrasound-guided transbronchial node biopsy,Feng′s EBUS-... 目的:探讨经皮二氧化碳分压(transcutaneous partial pressure of carbon dioxide,PtcCO_(2))监测在硬质支气管镜下冯氏气管内超声引导纵隔切开活检(Feng′s endobronchial ultrasound-guided transbronchial node biopsy,Feng′s EBUS-TBNB)中的应用。方法:收集2019年8月—2022年8月期间天津医科大学总医院收治的纵隔疾病患者128例,随机分成Feng′s EBUS-TBNB组和支气管内超声引导针吸活检术(endobronchial ultrasound-guided transbronchial needle aspiration,EBUS-TBNA)组,患者均予高频喷射通气行硬质支气管镜下操作及PtcCO_(2)监测,EBUS-TBNA组患者行EBUS-TBNA,Feng′s EBUS-TBNB组患者行Feng′s EBUS-TBNB术,比较两组患者术前(T0)、通气开始时(T_(1))、通气10 min后(T_(2))、通气20 min后(T3)、通气30 min后(T_(4))、通气40 min后(T_(5))、通气50 min后(T_(6))、通气60 min后(T_(7))心率(heart rate,HR)、平均动脉压(mean arterial pressure,MAP)和PtcCO_(2)的变化。结果:T_(1)~T_(7)时,两组患者HR、MAP和PtcCO_(2)水平均明显高于T0时(P<0.05)。T0~T_(2)时,两组患者HR、MAP和PtcCO_(2)水平比较差异无统计学意义(P>0.05);T3~T_(5)时,Feng′s EBUS-TBNB组HR、MAP和PtcCO_(2)水平均明显高于EBUS-TBNA组(P<0.05);而T_(6)~T_(7)时,两组患者HR、MAP和PtcCO_(2)水平比较差异无统计学意义(P>0.05)。结论:将PtcCO_(2)应用于Feng′s EBUS-TBNB中,可间接反映患者HR、MAP水平变化,值得临床推广应用。 展开更多
关键词 纵隔疾病 经皮二氧化碳分压 硬质支气管镜 冯氏气管内超声引导纵隔切开活检 心率 平均动脉压
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基于线性密集台阵的2023年甘肃积石山M_(S)6.2地震断层低速带研究
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作者 吴柏辰 秦满忠 +3 位作者 郭晓 王亚红 孙点峰 温淑琳 《地震工程学报》 CSCD 北大核心 2024年第3期734-741,共8页
2023年12月18日,甘肃省积石山县发生M_(S)6.2逆冲型地震。该地震发生在祁连活动地块拉脊山北缘断裂带,在断裂两侧曾发生过20余次5级左右中强地震,地震活动频次高,因此研究拉脊山断裂带特征具有重要意义。根据拉脊山断裂走向和此次地震... 2023年12月18日,甘肃省积石山县发生M_(S)6.2逆冲型地震。该地震发生在祁连活动地块拉脊山北缘断裂带,在断裂两侧曾发生过20余次5级左右中强地震,地震活动频次高,因此研究拉脊山断裂带特征具有重要意义。根据拉脊山断裂走向和此次地震余震分布,在刘集乡布设一条线性密集台阵,利用不同方位的余震事件计算体波的走时延时和放大效应。结果表明,P波和S波分别存在6个采样点(约0.012 s)和15个采样点(约0.03 s)的走时延时,推断出台阵西侧存在一个约150 m宽近似垂直的断层低速带,且该结果与远震P波相似性系数矩阵结果一致。 展开更多
关键词 甘肃积石山M_(s)6.2地震 走时延时 体波放大效应 线性密集台阵 断层低速带
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Right Heart Failure Indicative of Ebstein’s Disease in Adulthood about a Case
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作者 Sana Samoura Alpha Koné +8 位作者 Ibrahima Sory 2 Sylla Mamadou Bachir Bah Morlaye Soumaoro Aly Samoura Aboulaye Camara Ibrahima Sory Barry Elhadj Yaya Balde Mariama Beavogui Mamadou Dadhi Balde 《World Journal of Cardiovascular Diseases》 2023年第9期613-618,共6页
Ebstein disease is a rare congenital malformation whose clinical presentation differs according to the anatomical form and age of the patient. In adults, it presents mainly in the form of right or global heart failure... Ebstein disease is a rare congenital malformation whose clinical presentation differs according to the anatomical form and age of the patient. In adults, it presents mainly in the form of right or global heart failure or rhythm disorders. Survival is exceptionally long in some forms. We report the case of a 70-year-old patient with Ebstein’s disease in right heart failure. 展开更多
关键词 Ebstein’s Disease Right heart Failure
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基于零模行波S变换时频矩阵的配电网单相接地故障定位方法
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作者 杨小磊 袁明哲 邹经鑫 《电力科学与技术学报》 CAS CSCD 北大核心 2024年第4期93-101,共9页
为提高配电网发生单相接地故障时的定位精度,提出一种基于电压零模行波S变换时频矩阵的选线和定位方法。首先,将各条馈线末端行波检测装置测得的行波信号解耦,得到故障电压零模行波;然后,在主馈线、一级和二级分支支路等特殊位置设置故... 为提高配电网发生单相接地故障时的定位精度,提出一种基于电压零模行波S变换时频矩阵的选线和定位方法。首先,将各条馈线末端行波检测装置测得的行波信号解耦,得到故障电压零模行波;然后,在主馈线、一级和二级分支支路等特殊位置设置故障,得到对应故障位置的S变换时频矩阵,建立确定故障支路的对比库;最后,将故障零模电压行波S变换时频矩阵与对比库中数据进行相似度对比,确定单相接地故障发生的馈线和所在支路,针对不同性质支路选取适应性最优的定位方法,实现配电网单相接地故障的精确定位。仿真结果表明:该方法的定位准确度高,且无须全网配备行波检测装置便能够实现配电网单相接地故障的精确定位。 展开更多
关键词 配电网 行波定位 s变换 矩阵相似度
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Design of a Biomedical Device to Reduce Anxiety Experienced by Patients Diagnosed with Parkinson’s Disease
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作者 Madhini Vigneswaran Anjali Menon 《Journal of Biomedical Science and Engineering》 2024年第3期57-71,共15页
Parkinson’s disease (PD) is a neurodegenerative disease that occurs due to loss of nerve cells that produce dopamine in the brain, affecting approximately 4 million people worldwide. PD patients often feel an increas... Parkinson’s disease (PD) is a neurodegenerative disease that occurs due to loss of nerve cells that produce dopamine in the brain, affecting approximately 4 million people worldwide. PD patients often feel an increase in anxiety levels daily. While there are medications/exercises to help relieve anxiety, there are limited methods to reduce anxiety without the help of a caretaker. As a result, MEDIC Foundation, a non-profit organization in British Columbia, Canada, is designing an automated system that consists of a wristband and an application which uses vi-bration therapy to help reduce anxiety of PD patients. Literature reviews were conducted to document the project’s needs. Phase I of the project focused on de-veloping a prototype for the application and phase II on developing the wrist-band. The team developed prototypes of a wristband that automatically applies vibration near the median nerve as the heart rate variability (HRV) deviates away from the normal threshold of the user, and an application that displays real-time heart rate variability signals as well as provides for relaxation. The development of the prototype is still in early progress. By creating this automated system, we aim to provide a solution to senior PD patients to relieve anxiety independently. . 展开更多
关键词 Vibration Therapy Healthcare Application Parkinson’s Disease ANXIETY WRIsTBAND heart Rate Variability
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具有饱和恢复率的SEIR时滞模型的行波解
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作者 卫珍妮 《西北师范大学学报(自然科学版)》 2024年第1期20-29,共10页
研究一类具有饱和恢复率的SEIR时滞模型的行波解.首先,考虑一类二维系统初值问题的适定性;然后,通过构造一对有界的向量值上、下解得到一个闭凸集;最后,利用Schauder不动点定理证明:当基本再生数R^(0)>1,波速c>c^(*)时模型存在非... 研究一类具有饱和恢复率的SEIR时滞模型的行波解.首先,考虑一类二维系统初值问题的适定性;然后,通过构造一对有界的向量值上、下解得到一个闭凸集;最后,利用Schauder不动点定理证明:当基本再生数R^(0)>1,波速c>c^(*)时模型存在非平凡行波解. 展开更多
关键词 sEIR模型 饱和恢复率 时滞 行波解 sCHAUDER不动点定理
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Manual Order Picking Route Optimization in Distribution Warehouse of Chain Furniture Retail Enterprise
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作者 Yongzhen Zeng Junkun Wang +1 位作者 Ching-Kuei Kao King-Zoo Tang 《American Journal of Operations Research》 2024年第3期105-136,共32页
Due to the effects of the COVID-19 pandemic and the rise of online shopping, the offline sales of IKEA Fuzhou have been declining since 2020. Because the cost of distribution warehouse is a major expense for offline c... Due to the effects of the COVID-19 pandemic and the rise of online shopping, the offline sales of IKEA Fuzhou have been declining since 2020. Because the cost of distribution warehouse is a major expense for offline chain furniture retailers, and the picking process is a key activity in distribution warehouse operations. To reduce the cost of distribution warehouse and alleviate the survival pressure of the offline chain furniture retailers, this paper focuses on optimizing the picking route of the IKEA Fuzhou distribution warehouse. It starts by creating a two-dimensional coordinate system for the storage location of the distribution warehouse using the traditional S-type picking strategy to calculate the distance and time of the sorting route. Then, the problem of optimizing the picking route is then transformed into the travelling salesman problem (TSP), and picking route optimization model is developed using a genetic algorithm to analyze the sorting efficiency and picking route optimization. Results show that the order-picking route using the genetic algorithm strategy is significantly better than the traditional S-type picking strategy, which can improve overall sorting efficiency and operations, reduce costs, and increase efficiency. Thus, this establishes an implementation process for the order-picking path based on genetic algorithm optimization to improve overall sorting efficiency and operations, reduce costs, increase efficiency, and alleviate the survival pressure of pandemic-affected enterprises. 展开更多
关键词 s-shaped Picking strategy Picking Route traveling salesman Problem Genetic Algorithm
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不同下壁导联室性早搏R/S波比值的慢性心力衰竭患者近期预后随访分析
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作者 陈航 曾久鑫 《西藏医药》 2024年第2期13-15,共3页
目的对不同下壁导联室性早搏R/S波比值的慢性心力衰竭患者近期预后随访进行分析。方法选择2020年3月~2022年3月本院收治的93例动态心电图检查存在室性早搏的CHF患者93例。所有患者完善24h动态心电图检查,随访一年。依照近期预后进行分组... 目的对不同下壁导联室性早搏R/S波比值的慢性心力衰竭患者近期预后随访进行分析。方法选择2020年3月~2022年3月本院收治的93例动态心电图检查存在室性早搏的CHF患者93例。所有患者完善24h动态心电图检查,随访一年。依照近期预后进行分组,将出现急性心肌梗死、恶性心律失常等不良心脏事件纳入预后不良组(n=37),其余未出现心脏不良事件的患者纳入预后良好组(n=56)。比较两组不同下壁导联室性早搏R/S波比值的预后。结果两组在年龄、BMI、吸烟、高血压、糖尿病、LVEF、利尿剂、地高辛方面差异无统计学意义(P>0.05);两组在性别、NYHA分级上差异有统计学意义(P<0.05);预后良好组R/S比值≥1例数比率高于预后不良组,R/S比值<1例数比例低于预后不良组,差异有统计学意义(P<0.05)。Logistic回归分析显示,R/S比值<1与性别、NYHA分级均是CHF患者近期预后不良的独立危险因素(P<0.05)。结论不同下壁导联的室性早搏R/S比值与其预后具有相关性,R/S比值<1是其不良预后的预测因素。 展开更多
关键词 慢性心力衰竭 下壁导联室性早搏 R/s波比值 预后
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慢性心力衰竭患者血清sICAM-1、Lp-PLA2、CatS的表达水平及对近期预后的预测价值 被引量:4
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作者 陈刚 信鹏程 +1 位作者 陈文宽 陈红卫 《中国循证心血管医学杂志》 2023年第2期210-212,217,共4页
目的探讨慢性心力衰竭(心衰)患者血清可溶性细胞黏附分子-1(sICAM-1)、脂蛋白相关磷脂酶A2(Lp-PLA2)、蛋白酶S(CatS)的表达水平及对近期预后的预测价值。方法选择2021年1月至2022年6月于郑州市第七人民医院心内科就诊的85例慢性心衰患... 目的探讨慢性心力衰竭(心衰)患者血清可溶性细胞黏附分子-1(sICAM-1)、脂蛋白相关磷脂酶A2(Lp-PLA2)、蛋白酶S(CatS)的表达水平及对近期预后的预测价值。方法选择2021年1月至2022年6月于郑州市第七人民医院心内科就诊的85例慢性心衰患者作为研究对象(病例组),另选取我院同期体检的健康人群80例为对照组,分析两组患者血清sICAM-1、Lp-PLA2、CatS水平变化及对近期预后的预测价值。结果病例组患者血清sICAM-1、Lp-PLA2、CatS水平显著高于对照组,差异有统计学意义(P<0.05);NYHA分级心功能Ⅱ级患者血清sICAM-1、Lp-PLA2、CatS水平显著低于心功能Ⅲ级、Ⅳ级患者,心功能Ⅲ级患者血清sICAM-1、Lp-PLA2、CatS水平显著低于心功能Ⅳ级患者,差异有统计学意义(P<0.05);预后不良组患者血清sICAM-1、Lp-PLA2、CatS水平显著高于预后良好组,差异有统计学意义(P<0.05)。ROC曲线分析显示,血清sICAM-1预测慢性心衰预后的AUC为0.944,灵敏度为78.30%,特异度为87.10%,截断值为568.44μg/L;血清Lp-PLA2预测慢性心衰预后的AUC为0.974,灵敏度为71.00%,特异度为92.90%,截断值为74.23 ng/ml;血清CatS预测慢性心衰预后的AUC为0.818,灵敏度为63.10%,特异度为70.60%,截断值为57.61 ng/ml(P<0.05)。结论慢性心衰患者中血清sICAM-1、Lp-PLA2、CatS表达异常,与病情程度关系密切,可作为评估预后的指标之一。 展开更多
关键词 慢性心力衰竭 可溶性细胞黏附分子-1 脂蛋白相关磷脂酶A2 蛋白酶s 预测价值
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Love Is Intensified by Absence- Book Review on "The Time Traveler's Wife"
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作者 钟晓菁 《海外英语》 2012年第7X期225-226,共2页
In this paper,a review was finished according to a novel-"The Time Traveler's Wife".It use time travel to explore miscommunication and distance in relationships.A lot of knowledge could be obtained from ... In this paper,a review was finished according to a novel-"The Time Traveler's Wife".It use time travel to explore miscommunication and distance in relationships.A lot of knowledge could be obtained from the passage. 展开更多
关键词 BOOK REVIEW The Time traveler’s WIFE Miscommunicat
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Denial of Sartre's Existentialism in The Time Traveler's Wife
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作者 牛丽军 《海外英语》 2016年第17期163-165,共3页
By contrast with Sartre's existentialism,The Time Traveler's Wife depicts another humanistic world.Moreover,such things as meaning,reason,compensation and peace are indispensable in this world.
关键词 the time traveler’s wife sARTRE EXIsTENTIALIsM
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A lamp In The House, a lamp in the heart——Katherine Mansfield and her The Doll's House
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作者 杨晖 《白城师范高等专科学校学报》 2002年第1期39-41,共3页
"When dear old Mrs. Hay went back to town after staying with the Burnells she sent the children a doll's house." There are three girls in the Burnells , one is Isabel---the eldest sister, the second one ... "When dear old Mrs. Hay went back to town after staying with the Burnells she sent the children a doll's house." There are three girls in the Burnells , one is Isabel---the eldest sister, the second one is Lottie, and the third one is Kezia. Kazia is the heroine of the story. When the marvellous house stood in the garden, the Burnell children sounded as though they were in despair. 展开更多
关键词 Katherine Mansfield and her The Doll’s House a lamp in the heart A lamp In The House
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Effect of nursing intervention based on Maslow's hierarchy of needs in patients with coronary heart disease interventional surgery 被引量:19
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作者 Ji-Xue Xu Lin-Xue Wu +1 位作者 Wei Jiang Gui-Hong Fan 《World Journal of Clinical Cases》 SCIE 2021年第33期10189-10197,共9页
BACKGROUND It is very important to provide effective nursing programs to regulate the physical and mental state of patients and to improve treatment compliance after interventional surgery for coronary heart disease(C... BACKGROUND It is very important to provide effective nursing programs to regulate the physical and mental state of patients and to improve treatment compliance after interventional surgery for coronary heart disease(CHD).AIM To explore the effect of a nursing intervention based on Maslow’s hierarchy of needs theory on patients with CHD undergoing percutaneous coronary intervention.METHODS Ninety-four patients with CHD undergoing interventional surgery in our hospital from January 2020 to February 2021 were randomly divided into a research group(n=47)and a control group(n=47).The control group received routine nursing,and the research group received a nursing intervention based on Maslow’s hierarchy of needs theory.The scores of self-efficacy,negative emotion[depression(SDS),anxiety(SAS)],intervention compliance(standardized medication,moderate exercise,healthy diet,and regular review),and nursing satisfaction were calculated before and after intervention for the two groups.RESULTS Before intervention,there was no significant difference in the scores of disease general management self-efficacy,disease management self-efficacy,and total self-efficacy between the two groups(P=0.795,0.479,and 0.659,respectively).After intervention,these three scores in the research group were higher than those in the control group(P<0.001).Before intervention,there was no significant difference in the scores of SAS and SDS between the two groups(P=0.149 and 0.347,respectively).After intervention,the scores of SAS and SDS in the research group were lower than those in the control group(P<0.001).The standardized drug use rate(97.87%),moderate exercise rate(97.87%),healthy diet rate(95.74%),and regular reexamination rate(97.87%)in the research group were higher than those in the control group(85.11%,82.98%,80.85%,and 87.23%,respectively)(P=0.027,0.014,0.025,and 0.049,respectively).Nursing job satisfaction in the research group(93.62%)was higher than that in the control group(78.72%)(P=0.036).CONCLUSION A nursing program based on Maslow’s hierarchy of needs theory can effectively alleviate negative emotion,enhance self-efficacy and intervention compliance,and ensure that the patients are highly satisfied with the nursing work. 展开更多
关键词 Maslow’s hierarchy of needs NURsING Coronary heart disease Interventional surgery COMPLIANCE
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REMARK ON CRITICAL SPEED OF TRAVELING WAVEFRONTS FOR NICHOLSON'S BLOWFLIES EQUATION WITH DIFFUSION 被引量:2
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作者 危地 吴教育 梅铭 《Acta Mathematica Scientia》 SCIE CSCD 2010年第5期1561-1566,共6页
This note is devoted to the son's blowflies equation with diffusion, a critical speed of traveling waves, we give behavior with respect to the mature age study on the traveling wavefronts to the Nicholtime-delayed re... This note is devoted to the son's blowflies equation with diffusion, a critical speed of traveling waves, we give behavior with respect to the mature age study on the traveling wavefronts to the Nicholtime-delayed reaction-diffusion equation. For the a detailed analysis on its location and asymptotic 展开更多
关键词 Nicholson's blowflies equation traveling wavefronts critical wave-speed
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Cardiac damage in athlete's heart: When the “supernormal” heart fails! 被引量:3
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作者 Andreina Carbone Antonello D’Andrea +8 位作者 Lucia Riegler Raffaella Scarafile Enrica Pezzullo Francesca Martone Raffaella America Biagio Liccardo Maurizio Galderisi Eduardo Bossone Raffaele Calabrò 《World Journal of Cardiology》 CAS 2017年第6期470-480,共11页
Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological ... Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological cardiac modeling in athletes is associated with normal or enhanced cardiac function, but recent studies have documented decrements in left ventricular function during intense exercise and the release of cardiac markers of necrosis in athlete's blood of uncertain significance. Furthermore, cardiac remodeling may predispose athletes to heart disease and result in electrical remodeling, responsible for arrhythmias. Athlete's heart is a physiological condition and does not require a specific treatment. In some conditions, it is important to differentiate the physiological adaptations from pathological conditions, such as hypertrophic cardiomyopathy, arrhythmogenic dysplasia of the right ventricle, and non-compaction myocardium, for the greater risk of sudden cardiac death of these conditions. Moreover, some drugs and performance-enhancing drugs can cause structural alterations and arrhythmias, therefore, their use should be excluded. 展开更多
关键词 Athlete’s heart Cardiac damage FIBROsIs Intense exercise Arrhythmogenic dysplasia of the right ventricle Atrial fibrillation Doping Anabolic-androgenic steroids Hypertrophic cardiomyopathy
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Screen for stage-specific expression genes between tail bud stage and heartbeat beginning stage in embryogenesis of gynogenetic silver crucian carp 被引量:17
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作者 YAO HUA SHI, JUN LIU, JIAN HONG XIA, JIAN FANG GUIState Key laboratory of Freshwater Ecology and Biotechnology, Wuhan Center for Developmental Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China 《Cell Research》 SCIE CAS CSCD 2002年第2期133-142,共10页
A systemic study was initiated to identify stage-specific expression genes in fish embryogenesis by using suppression subtractive hybridization (SSH) technique. In this study, we presented a preliminary result on scre... A systemic study was initiated to identify stage-specific expression genes in fish embryogenesis by using suppression subtractive hybridization (SSH) technique. In this study, we presented a preliminary result on screen for stage-specific expression genes between tail bud stage (TBS) and heartbeat beginning stage (HBS) in gynogenetic silver crucian carp (Carassius auratus gibelio). Two SSH plasmid libraries specific for TBS embryos and HBS embryos were constructed, and stage-specific expression genes were screened between the two stages. 1963 TBS positive clones and 2466 HBS positive clones were sampled to PCR amplification, and 1373 TBS and 1809 HBS PCR positive clones were selected to carry out dot blots. 169 TBS dot blot positive clones and 272 HBS dot blot positive clones were sequenced. Searching GenBank by using these nucleotide sequences indicated that most of the TBS dot blot positive clones could not be found homologous sequences in the database, while known genes were mainly detected from HBS dot blot positive clones. Of the 79 known genes, 20 were enzymes or kinases involved in important metabolism of embryonic development. Moreover, specific expressions of partial genes were further confirmed by virtual northern blots. This study is the first step for making a large attempt to study temporal and spatial control of gene expression in the gynogenetic fish embryogenesis. 展开更多
关键词 Gene Expression Regulation Developmental Animals Blotting Northern CARPs Cloning Molecular DNA Complementary Gene Library heart Nucleic Acid Hybridization Plasmids Polymerase Chain Reaction RNA Messenger Research support Non-U.s. Gov't Tail
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Mediative Sugeno’s-TSK Fuzzy Logic Based Screening Analysis to Diagnosis of Heart Disease 被引量:1
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作者 Nitesh Dhiman Mukesh Kumar Sharma 《Applied Mathematics》 2019年第6期448-467,共20页
Fuzzy logic is an approach which deals with the incomplete information to handle the imperfect knowledge. In the present research paper we have proposed a new approach that can handle the imperfect knowledge, in a bro... Fuzzy logic is an approach which deals with the incomplete information to handle the imperfect knowledge. In the present research paper we have proposed a new approach that can handle the imperfect knowledge, in a broader way that we will consider the unfavourable case also as the intuitionistic fuzzy logic does. The mediative fuzzy logic is an extensive approach of intuitionistic fuzzy logic, which provides a solution, when there is a contradiction in the expert knowledge for favourable as well as unfavourable cases. The purpose of the present paper is to design a mediative fuzzy inference system based Sugeno-TSK model for the diagnosis of heart disease. Our proposed method is the extension of Sugeno-TSK fuzzy logic controller in the form of Sugeno-TSK mediative fuzzy logic controller. 展开更多
关键词 FUZZY LOGIC Intuitionistic FUZZY LOGIC Mediative FUZZY LOGIC sugeno’s FUZZY Controller FUZZY RULE FIRING Level heart Disease
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Analysis of Satire in Jonathan Swift’s Gulliver’s Travels
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作者 陈俊 《海外英语》 2012年第18期181-182,188,共3页
As one of Jonathan Swift masterpieces, Gulliver's Travels chronicles Lemuel Gulliver's four odd voyages in the form of a travel log. With sharp satire, Swift ridicules vices of England and the whole Europe in ... As one of Jonathan Swift masterpieces, Gulliver's Travels chronicles Lemuel Gulliver's four odd voyages in the form of a travel log. With sharp satire, Swift ridicules vices of England and the whole Europe in the early 18th century. The article ana lyzes the art and specific usage of satiric techniques in Gulliver's Travels. 展开更多
关键词 sATIRE jonathan sWIFT Gulliver’s travels
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Assessment of Cardiac Autonomic Function by Using Heart Rate Turbulence in Behcet’s Disease 被引量:2
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作者 Onder Akci Mustafa Aldemir +4 位作者 Fatma Yaman Ozlem Solak Sadik Volkan Emren Ersel Onrat Alaeddin Avsar 《World Journal of Cardiovascular Surgery》 2014年第11期193-199,共7页
Behcet’s disease (BD) is a chronic inflammatory disorder that can affect many systems in the body. Cardiac involvement increases the risk of cardiovascular mortality and occurs in 1%-5% of patients with BD. Ventricul... Behcet’s disease (BD) is a chronic inflammatory disorder that can affect many systems in the body. Cardiac involvement increases the risk of cardiovascular mortality and occurs in 1%-5% of patients with BD. Ventricular arrythmias are believed to be the cause of this increased risk of cardiovascular mortality and it is also thought to be related with cardiac autonomic dysfunction. Heart rate turbulence (HRT) is a new predictor of cardiac autonomic activity. HRT is an independent and powerful predictor of mortality. In this study, we investigated the cardiac autonomic activity which can be determined by HRT in patients with BD. Forty patients with BD (20 men, mean age: 40 ± 9 years, range: 27-55 years) were diagnosed according to the International Study Group Criteria (ISGC) and gender and age matched healthy volunteers (20 men, mean age: 39 ± 8 years, range: 26-56 years) were included in this study. All of the participants (patients and controls) underwent 24 hours Holter electrocardiogram. HRT parameters, turbulence onset (TO) and turbulence slope (TS) were calculated with HRT (View Version 0.60-0.1 of Software Program). There were no significant differences in TO and TS values between patients with BD and control subject (TO-BD: 0.014 ± 0.03, TO-Control: 0.011 ± 0.04;TS-BD: 7.88 ± 4.9, TS-Control: 9.42 ± 6.7 respectively). Although increased cardiovascular mortality rates in BD have been shown in many studies, HRT values—detecting the risk of sudden death—do not seem to be altered in this disease. 展开更多
关键词 Behcet’s Disease heart Rate Turbulence sudden Cardiac Death Cardiac Autonomic Activity
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