The relationship between the Heaven and human beings is a central issue in the transformation of Confucianism in the Mid-Tang Dynasty.The discourses on the Heaven by Han Yu,Liu Zongyuan,and Liu Yuxi helped to promote ...The relationship between the Heaven and human beings is a central issue in the transformation of Confucianism in the Mid-Tang Dynasty.The discourses on the Heaven by Han Yu,Liu Zongyuan,and Liu Yuxi helped to promote the transformation and greatly influenced the transformation in literature.The differences in the poetry among the three authors may also be interpreted from the perspective of their perceptions of the Heaven—Han Yu’s discourse on the Heaven focused on the enemy-relationship between the Heaven and human beings,so his poems always showed tension and loss.Liu Zongyuan was interested in the alienation between the heaven and human beings,so his poems were more rational and placid than Han Yu’s.However,Liu Yuxi’s discourse on the Heaven paid attention to the positive influence of the Heaven on human beings,and most of his poems were filled with reason.The changes in the relationship between the Heaven and human beings lead to the broadened themes,innovated vocabulary,diversified styles,and varied fresh imageries.Likewise,the relationship between the Heaven and human beings established in the Song Dynasty led accordingly to a new type of literature different from the Tang literature.展开更多
This paper makes a comparative study of the theory of heavenly principles and human desires in the Neo-Confucianism of the Song and Ming Dynasties and the theory of personality structure in psychoanalytic theory.From ...This paper makes a comparative study of the theory of heavenly principles and human desires in the Neo-Confucianism of the Song and Ming Dynasties and the theory of personality structure in psychoanalytic theory.From the perspective of the construction of the subject,in the debate between the heavenly principle and the human desire,the person is built into the moral subject.The id,ego,and super-ego in the psychoanalytic theory constitute the unconscious structural subject.In the framework of these two theories,the“maintain the heavenly principles and eradicate human desires”and“the heavenly principles exist in desire”in the theory of heavenly principles and human desires express the unity of opposites between heavenly principles and human desire.The core of personality structure theory is the relationship of obedience and control among the id,ego,and super-ego.As far as the value orientation is concerned,the debate between the heavenly principle and the human desire provides a theoretical basis for the moral practice of Confucianism of“aim at absolute perfection”,while the free will of the id in the unconscious subject is the most essential ethical aspect of psychoanalysis.展开更多
Kuo,Yeh-Tzu founded Taiwan’s Sung Shan Tsu Huei Temple in 1970.She organized more than 200 worshipers as a group named“Taiwan Tsu Huei Temple Queen Mother of the West Delegation to China to Worship at the Ancestral ...Kuo,Yeh-Tzu founded Taiwan’s Sung Shan Tsu Huei Temple in 1970.She organized more than 200 worshipers as a group named“Taiwan Tsu Huei Temple Queen Mother of the West Delegation to China to Worship at the Ancestral Temples”in 1990.At that time,the temple building of the Queen Mother Palace in Huishan of Gansu Province was in disrepair,and Temple Master Kuo,Yeh-Tzu made a vow to rebuild it.Rebuilding the ancestral temple began in 1992 and was completed in 1994.It was the first case of a Taiwan temple financing the rebuilding of a far-away Queen Mother Palace with its own donations.In addition,Sung Shan Tsu Huei Temple celebrated its 45th anniversary and hosted Yiwei Yuanheng Lizhen Daluo Tiandi Qingjiao(Momentous and Fortuitous Heaven and Earth Prayer Ceremony)in 2015.This is the most important and the grandest blessing ceremony of Taoism,a rare event for Taoism locally and abroad during this century.Those sacred rituals were replete with unprecedented grand wishes to propagate the belief in Queen Mother of the West.Stopping at nothing,Queen Mother’s love never ceases.展开更多
This paper introduces the relations between human and the nature in traditional Chinese medicine(TCM).TCM is a science dedicated to studies on laws of human life activities.
Understanding the dynamics of surface water area and their drivers is crucial for human survival and ecosystem stability in inland arid and semi-arid areas.This study took Gansu Province,China,a typical area with comp...Understanding the dynamics of surface water area and their drivers is crucial for human survival and ecosystem stability in inland arid and semi-arid areas.This study took Gansu Province,China,a typical area with complex terrain and variable climate,as the research subject.Based on Google Earth Engine,we used Landsat data and the Open-surface Water Detection Method with Enhanced Impurity Control method to monitor the spatiotemporal dynamics of surface water area in Gansu Province from 1985 to 2022,and quantitatively analyzed the main causes of regional differences in surface water area.The findings revealed that surface water area in Gansu Province expanded by 406.88 km2 from 1985 to 2022.Seasonal surface water area exhibited significant fluctuations,while permanent surface water area showed a steady increase.Notably,terrestrial water storage exhibited a trend of first decreasing and then increasing,correlated with the dynamics of surface water area.Climate change and human activities jointly affected surface hydrological processes,with the impact of climate change being slightly higher than that of human activities.Spatially,climate change affected the'source'of surface water to a greater extent,while human activities tended to affect the'destination'of surface water.Challenges of surface water resources faced by inland arid and semi-arid areas like Gansu Province are multifaceted.Therefore,we summarized the surface hydrology patterns typical in inland arid and semi-arid areas and tailored surface water'supply-demand'balance strategies.The study not only sheds light on the dynamics of surface water area in Gansu Province,but also offers valuable insights for ecological protection and surface water resource management in inland arid and semi-arid areas facing water scarcity.展开更多
With the shocking power of sci-fi scenes,the creativity of sci-fi imagination and the cognition of sci-fi humanities,The Wandering Earth II has given multiple expressions of Chinese emotions and Chinese spirit.It crea...With the shocking power of sci-fi scenes,the creativity of sci-fi imagination and the cognition of sci-fi humanities,The Wandering Earth II has given multiple expressions of Chinese emotions and Chinese spirit.It creates a national,scientific and popular new narrative discourse for Chinese science fiction oriented to modernization,the world and the future.展开更多
THIS photograph was published in the book, A Century of Historical Chinese Photographs, with only a one-line caption: "A private school for Christian girls opened by the foreign Mission of the Virgin Mary in Shan...THIS photograph was published in the book, A Century of Historical Chinese Photographs, with only a one-line caption: "A private school for Christian girls opened by the foreign Mission of the Virgin Mary in Shanghai." Determining which country’s church, which year it opened, and what kind of a private girls’ school it was would be nearly impossible. But this should not stop展开更多
Energy is the basis of human development and the impetus of society progress. There are three sources of energy: energy of celestial body outside the Earth, the Earth energy and energy of interaction between the Earth...Energy is the basis of human development and the impetus of society progress. There are three sources of energy: energy of celestial body outside the Earth, the Earth energy and energy of interaction between the Earth and other celestial bodies. Meanwhile, there are three scales of co-evolution: the evolution of the Sun-Earth-Moon system on an ultra-long time scale has provided energy sources and extra-terrestrial environmental conditions for the formation of the Earth system;the evolution of the Earth system on a long time scale has provided the material preconditions such as energy resources and suitable sphere environment for life birth and the human development;on a short time scale, the development of human civilization makes the human circle break through the Earth system, expanding the extraterrestrial civilization. With the co-evolution, there are three processes in the carbon cycle: inorganic carbon cycle, short-term organic carbon cycle and long-term organic carbon cycle, which records human immoderate utilization of fossil energy and global sphere reforming activities, breaking the natural balance and closed-loop path of the carbon cycle of the Earth, causing the increase of greenhouse gases and global climate change, affecting human happiness and development. The energy transition is inevitable, and carbon neutrality must be realized. Building the green energy community is a fundamental measure to create the new energy system under carbon neutrality target. China is speeding up its energy revolution and developing a powerful energy nation. It is necessary to secure the cornerstone of the supply of fossil energy and forge a strong growing pole for green and sustainable development of new energy. China energy production and consumption structure will make a revolutionary transformation from the type of fossil energy domination to the type of new energy domination, depending on a high-level self-reliance of science and technology and a high-quality green energy system of cleaning, low-carbon, safety, efficiency and independence. Energy development has three major trends: low-carbon fossil energy, large-scale new energy and intelligent energy system, relying on the green innovation, contributing the green energy and constructing the green homeland.展开更多
Information on rare earth elements(REEs)in soils and plants of the Qinghai-Tibet Plateau is very limited.Therefore,in this study,we performed field sampling to explore the geochemical signatures and human health risk ...Information on rare earth elements(REEs)in soils and plants of the Qinghai-Tibet Plateau is very limited.Therefore,in this study,we performed field sampling to explore the geochemical signatures and human health risk of REEs in soils and plants of the northeastern Qinghai-Tibet Plateau,China.A total of 127 soil samples and 127 plant samples were collected from the northeastern Qinghai-Tibet Plateau to acquire the geochemical signatures and related human health risks of REEs.The mean total concentrations of REEs in soils and plants of the study area reached 178.55 and 10.06 mg/kg,respectively.The light REEs in soils and plants accounted for 76%and 77%of the total REEs,respectively.REEs showed significantly homogenous distribution in soils but inhomogeneous distribution in plants of the study area.Characteristic parameters indicated that light REEs were enriched and fractionated significantly,while heavy REEs were moderately fractionated in soils and plants.REEs in soils and plants showed significantly negative Europium anomaly.Cerium showed slightly positive anomaly in plants and slight anomaly in soils.The normalized distribution patterns of REEs were generally similar in the analyzed soils and the corresponding plants of the study area.The average bio-concentration factor of REEs ranged from 0.0478(Scandium)to 0.0604(Europium),confirming a small accumulation of REEs by plants.Health risks caused by REEs in soils and plants were negligible,while risks for adults were lower than those for children.This study provides important information on REEs in soils and plants of the northeastern Qinghai-Tibet Plateau.展开更多
The old Chinese saying"to the people,food is heaven"is a good indication that the people of China are pretty serious about food and eating.Suffice it to say,they love to eat,and when they are not actually ea...The old Chinese saying"to the people,food is heaven"is a good indication that the people of China are pretty serious about food and eating.Suffice it to say,they love to eat,and when they are not actually eating,they are either talking about eating or planning what to eat next.展开更多
Integrated assessment models and coupled earth system models both have their limitations in understanding the interactions between human activity and the physical earth system. In this paper, a new human--earth system...Integrated assessment models and coupled earth system models both have their limitations in understanding the interactions between human activity and the physical earth system. In this paper, a new human--earth system model, BNU- HESM1.0, constructed by combining the economic and climate damage components of the Dynamic Integrated Model of Climate Change and Economy to the BNU-ESM model, is introduced. The ability of BNU-HESM1.0 in simulating the global CO2 concentration and surface temperature is also evaluated. We find that, compared to observation, BNU-HESM1.0 underestimates the global CO2 concentration and its rising trend during 1965-2005, due to the uncertainty in the economic components. However, the surface temperature simulated by BNU-HESM1.0 is much closer to observation, resulting from the overestimates of surface temperature by the original BNU-ESM model. The uncertainty of BNU-ESM falls within the range of present earth system uncertainty, so it is the economic and climate damage component of BNU-HESM 1.0 that needs to be improved through further study. However, the main purpose of this paper is to introduce a new approach to investigate the complex relationship between human activity and the earth system. It is hoped that it will inspire further ideas that prove valuable in guiding human activities appropriate for a sustainable future climate.展开更多
In the Anthropocene,health is necessary to achieve global sustainable development.This is a challenge because health issues are complex and span from humans to ecosystems and the environment through dynamic interac-ti...In the Anthropocene,health is necessary to achieve global sustainable development.This is a challenge because health issues are complex and span from humans to ecosystems and the environment through dynamic interac-tions across scales.We find that the health issues have been mainly addressed by disciplinary endeavors which unfortunately will not result in panoramic theories or effective solutions.We recommend focusing on the intri-cate interactions between humans,ecosystems and the environment for developing common theoretical under-standings and practical solutions for safeguarding planetary health,with human health as the key indicator and endpoint.To facilitate this paradigm shift,a holistic framework is formulated that incorporates disturbances from inner Earth and our solar system,and accommodates interactions between humans,ecosystems and the environ-ment in a nested hierarchy.An integrative and transdisciplinary health science is advocated along with holistic thinking to resolve our current health challenges and to achieve the health-related sustainable development goals.展开更多
The binding reaction between methyl pheophorbide-a-Gd (MPA-Gd) and Human Serum Albumins (HSA) was studied by fluorescence and UV-Vis absorption spectra. The results indicated that the binding reaction of them was a si...The binding reaction between methyl pheophorbide-a-Gd (MPA-Gd) and Human Serum Albumins (HSA) was studied by fluorescence and UV-Vis absorption spectra. The results indicated that the binding reaction of them was a single static quenching process, MPA-Gd strongly bound HSA, the binding equilibrium constant K0=2.298×105 L·mol-1 at 25 ℃. The shortest binding distance(r) and energy transfer efficiency(E) between donor (HSA) and acceptor (MPA-Gd) was obtained by Frster′s nonradiative energy transfer mechanism as follows: r=4.03 nm, E=0.12. The enthalpy change (ΔH) and entropy change (ΔS) were calculated at 25 and 37 ℃. The results indicated that the hydrogen bonds played major role in the reaction. Furthermore, the displacement experiments indicated that MPA-Gd could bind to the site Ⅱof HSA.展开更多
With the cultural myth that science can only determine the way the world "is" (facts), while humanities, social sciences, lawyers, philosophers, and theologians must determine the way the world "ought to be" (v...With the cultural myth that science can only determine the way the world "is" (facts), while humanities, social sciences, lawyers, philosophers, and theologians must determine the way the world "ought to be" (values), those in position of global-, national-, and local-political power make major decisions of the use (or non-use) of scientific knowledge and technology. As a result, the human being has created a non-scientifically based cultural environment that is affecting his ability to survive. In effect, cultural evolution is occurring more rapidly than biological evolution that can adapt to the changes brought about in the physical and psycho-social environments. In a pluralistic cultural world, where each society has generated a different view of human nature and different ethical values, the use, misuse, or non-use of scientific and technological advances are derived from these unscientific views of human nature. Since all life depends on limiting interacting environmental and ecological factors, it is imperative that scientific information be used to govern how to minimize irreversible effects on life-sustaining ecological factors, but also scientific information bearing on understanding human nature ought to be integrated into a "global bioethics". While ethical values cannot be directly derived from scientific factors, it is also true that human values or our "ought" cannot be maintained in ignorance or defiance of the facts or the "is".展开更多
文摘The relationship between the Heaven and human beings is a central issue in the transformation of Confucianism in the Mid-Tang Dynasty.The discourses on the Heaven by Han Yu,Liu Zongyuan,and Liu Yuxi helped to promote the transformation and greatly influenced the transformation in literature.The differences in the poetry among the three authors may also be interpreted from the perspective of their perceptions of the Heaven—Han Yu’s discourse on the Heaven focused on the enemy-relationship between the Heaven and human beings,so his poems always showed tension and loss.Liu Zongyuan was interested in the alienation between the heaven and human beings,so his poems were more rational and placid than Han Yu’s.However,Liu Yuxi’s discourse on the Heaven paid attention to the positive influence of the Heaven on human beings,and most of his poems were filled with reason.The changes in the relationship between the Heaven and human beings lead to the broadened themes,innovated vocabulary,diversified styles,and varied fresh imageries.Likewise,the relationship between the Heaven and human beings established in the Song Dynasty led accordingly to a new type of literature different from the Tang literature.
文摘This paper makes a comparative study of the theory of heavenly principles and human desires in the Neo-Confucianism of the Song and Ming Dynasties and the theory of personality structure in psychoanalytic theory.From the perspective of the construction of the subject,in the debate between the heavenly principle and the human desire,the person is built into the moral subject.The id,ego,and super-ego in the psychoanalytic theory constitute the unconscious structural subject.In the framework of these two theories,the“maintain the heavenly principles and eradicate human desires”and“the heavenly principles exist in desire”in the theory of heavenly principles and human desires express the unity of opposites between heavenly principles and human desire.The core of personality structure theory is the relationship of obedience and control among the id,ego,and super-ego.As far as the value orientation is concerned,the debate between the heavenly principle and the human desire provides a theoretical basis for the moral practice of Confucianism of“aim at absolute perfection”,while the free will of the id in the unconscious subject is the most essential ethical aspect of psychoanalysis.
文摘Kuo,Yeh-Tzu founded Taiwan’s Sung Shan Tsu Huei Temple in 1970.She organized more than 200 worshipers as a group named“Taiwan Tsu Huei Temple Queen Mother of the West Delegation to China to Worship at the Ancestral Temples”in 1990.At that time,the temple building of the Queen Mother Palace in Huishan of Gansu Province was in disrepair,and Temple Master Kuo,Yeh-Tzu made a vow to rebuild it.Rebuilding the ancestral temple began in 1992 and was completed in 1994.It was the first case of a Taiwan temple financing the rebuilding of a far-away Queen Mother Palace with its own donations.In addition,Sung Shan Tsu Huei Temple celebrated its 45th anniversary and hosted Yiwei Yuanheng Lizhen Daluo Tiandi Qingjiao(Momentous and Fortuitous Heaven and Earth Prayer Ceremony)in 2015.This is the most important and the grandest blessing ceremony of Taoism,a rare event for Taoism locally and abroad during this century.Those sacred rituals were replete with unprecedented grand wishes to propagate the belief in Queen Mother of the West.Stopping at nothing,Queen Mother’s love never ceases.
文摘This paper introduces the relations between human and the nature in traditional Chinese medicine(TCM).TCM is a science dedicated to studies on laws of human life activities.
基金This research was supported by the Third Xinjiang Scientific Expedition Program(2021xjkk010102)the National Natural Science Foundation of China(41261047,41761043)+1 种基金the Science and Technology Plan of Gansu Province,China(20YF3FA042)the Youth Teacher Scientific Capability Promoting Project of Northwest Normal University,Gansu Province,China(NWNU-LKQN-17-7).
文摘Understanding the dynamics of surface water area and their drivers is crucial for human survival and ecosystem stability in inland arid and semi-arid areas.This study took Gansu Province,China,a typical area with complex terrain and variable climate,as the research subject.Based on Google Earth Engine,we used Landsat data and the Open-surface Water Detection Method with Enhanced Impurity Control method to monitor the spatiotemporal dynamics of surface water area in Gansu Province from 1985 to 2022,and quantitatively analyzed the main causes of regional differences in surface water area.The findings revealed that surface water area in Gansu Province expanded by 406.88 km2 from 1985 to 2022.Seasonal surface water area exhibited significant fluctuations,while permanent surface water area showed a steady increase.Notably,terrestrial water storage exhibited a trend of first decreasing and then increasing,correlated with the dynamics of surface water area.Climate change and human activities jointly affected surface hydrological processes,with the impact of climate change being slightly higher than that of human activities.Spatially,climate change affected the'source'of surface water to a greater extent,while human activities tended to affect the'destination'of surface water.Challenges of surface water resources faced by inland arid and semi-arid areas like Gansu Province are multifaceted.Therefore,we summarized the surface hydrology patterns typical in inland arid and semi-arid areas and tailored surface water'supply-demand'balance strategies.The study not only sheds light on the dynamics of surface water area in Gansu Province,but also offers valuable insights for ecological protection and surface water resource management in inland arid and semi-arid areas facing water scarcity.
文摘With the shocking power of sci-fi scenes,the creativity of sci-fi imagination and the cognition of sci-fi humanities,The Wandering Earth II has given multiple expressions of Chinese emotions and Chinese spirit.It creates a national,scientific and popular new narrative discourse for Chinese science fiction oriented to modernization,the world and the future.
文摘THIS photograph was published in the book, A Century of Historical Chinese Photographs, with only a one-line caption: "A private school for Christian girls opened by the foreign Mission of the Virgin Mary in Shanghai." Determining which country’s church, which year it opened, and what kind of a private girls’ school it was would be nearly impossible. But this should not stop
文摘Energy is the basis of human development and the impetus of society progress. There are three sources of energy: energy of celestial body outside the Earth, the Earth energy and energy of interaction between the Earth and other celestial bodies. Meanwhile, there are three scales of co-evolution: the evolution of the Sun-Earth-Moon system on an ultra-long time scale has provided energy sources and extra-terrestrial environmental conditions for the formation of the Earth system;the evolution of the Earth system on a long time scale has provided the material preconditions such as energy resources and suitable sphere environment for life birth and the human development;on a short time scale, the development of human civilization makes the human circle break through the Earth system, expanding the extraterrestrial civilization. With the co-evolution, there are three processes in the carbon cycle: inorganic carbon cycle, short-term organic carbon cycle and long-term organic carbon cycle, which records human immoderate utilization of fossil energy and global sphere reforming activities, breaking the natural balance and closed-loop path of the carbon cycle of the Earth, causing the increase of greenhouse gases and global climate change, affecting human happiness and development. The energy transition is inevitable, and carbon neutrality must be realized. Building the green energy community is a fundamental measure to create the new energy system under carbon neutrality target. China is speeding up its energy revolution and developing a powerful energy nation. It is necessary to secure the cornerstone of the supply of fossil energy and forge a strong growing pole for green and sustainable development of new energy. China energy production and consumption structure will make a revolutionary transformation from the type of fossil energy domination to the type of new energy domination, depending on a high-level self-reliance of science and technology and a high-quality green energy system of cleaning, low-carbon, safety, efficiency and independence. Energy development has three major trends: low-carbon fossil energy, large-scale new energy and intelligent energy system, relying on the green innovation, contributing the green energy and constructing the green homeland.
基金the One Hundred Talents Program of Chinese Academy of Sciences(Y610061033)the Kunlun Talent Action Plan of Qinghai Province,China(E140WX42)+2 种基金the Science and Technology Plan Protect of Qinghai Province,China(2021-ZJ-T07)the Taishan Scholar Program of Shandong Province,China(tsqn201812116)the Two-Hundred Talents Plan of Yantai City of Shandong Province,China。
文摘Information on rare earth elements(REEs)in soils and plants of the Qinghai-Tibet Plateau is very limited.Therefore,in this study,we performed field sampling to explore the geochemical signatures and human health risk of REEs in soils and plants of the northeastern Qinghai-Tibet Plateau,China.A total of 127 soil samples and 127 plant samples were collected from the northeastern Qinghai-Tibet Plateau to acquire the geochemical signatures and related human health risks of REEs.The mean total concentrations of REEs in soils and plants of the study area reached 178.55 and 10.06 mg/kg,respectively.The light REEs in soils and plants accounted for 76%and 77%of the total REEs,respectively.REEs showed significantly homogenous distribution in soils but inhomogeneous distribution in plants of the study area.Characteristic parameters indicated that light REEs were enriched and fractionated significantly,while heavy REEs were moderately fractionated in soils and plants.REEs in soils and plants showed significantly negative Europium anomaly.Cerium showed slightly positive anomaly in plants and slight anomaly in soils.The normalized distribution patterns of REEs were generally similar in the analyzed soils and the corresponding plants of the study area.The average bio-concentration factor of REEs ranged from 0.0478(Scandium)to 0.0604(Europium),confirming a small accumulation of REEs by plants.Health risks caused by REEs in soils and plants were negligible,while risks for adults were lower than those for children.This study provides important information on REEs in soils and plants of the northeastern Qinghai-Tibet Plateau.
文摘The old Chinese saying"to the people,food is heaven"is a good indication that the people of China are pretty serious about food and eating.Suffice it to say,they love to eat,and when they are not actually eating,they are either talking about eating or planning what to eat next.
基金funded by the National Key Program for Global Change Research of China(Grant No.2010CB950504)the National Basic Research Program of China(973 Program)(Grant No. 2012CB95570001)the nationallevel major cultivation project of Guangdong Province entitled:"The construction and application of coupled earth system and social economic models"(Grant No.2014GKXM058)
文摘Integrated assessment models and coupled earth system models both have their limitations in understanding the interactions between human activity and the physical earth system. In this paper, a new human--earth system model, BNU- HESM1.0, constructed by combining the economic and climate damage components of the Dynamic Integrated Model of Climate Change and Economy to the BNU-ESM model, is introduced. The ability of BNU-HESM1.0 in simulating the global CO2 concentration and surface temperature is also evaluated. We find that, compared to observation, BNU-HESM1.0 underestimates the global CO2 concentration and its rising trend during 1965-2005, due to the uncertainty in the economic components. However, the surface temperature simulated by BNU-HESM1.0 is much closer to observation, resulting from the overestimates of surface temperature by the original BNU-ESM model. The uncertainty of BNU-ESM falls within the range of present earth system uncertainty, so it is the economic and climate damage component of BNU-HESM 1.0 that needs to be improved through further study. However, the main purpose of this paper is to introduce a new approach to investigate the complex relationship between human activity and the earth system. It is hoped that it will inspire further ideas that prove valuable in guiding human activities appropriate for a sustainable future climate.
基金This work was financially supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA23070201)The Science-based Advisory Program of the Alliance of International Science Organizations。
文摘In the Anthropocene,health is necessary to achieve global sustainable development.This is a challenge because health issues are complex and span from humans to ecosystems and the environment through dynamic interac-tions across scales.We find that the health issues have been mainly addressed by disciplinary endeavors which unfortunately will not result in panoramic theories or effective solutions.We recommend focusing on the intri-cate interactions between humans,ecosystems and the environment for developing common theoretical under-standings and practical solutions for safeguarding planetary health,with human health as the key indicator and endpoint.To facilitate this paradigm shift,a holistic framework is formulated that incorporates disturbances from inner Earth and our solar system,and accommodates interactions between humans,ecosystems and the environ-ment in a nested hierarchy.An integrative and transdisciplinary health science is advocated along with holistic thinking to resolve our current health challenges and to achieve the health-related sustainable development goals.
文摘The binding reaction between methyl pheophorbide-a-Gd (MPA-Gd) and Human Serum Albumins (HSA) was studied by fluorescence and UV-Vis absorption spectra. The results indicated that the binding reaction of them was a single static quenching process, MPA-Gd strongly bound HSA, the binding equilibrium constant K0=2.298×105 L·mol-1 at 25 ℃. The shortest binding distance(r) and energy transfer efficiency(E) between donor (HSA) and acceptor (MPA-Gd) was obtained by Frster′s nonradiative energy transfer mechanism as follows: r=4.03 nm, E=0.12. The enthalpy change (ΔH) and entropy change (ΔS) were calculated at 25 and 37 ℃. The results indicated that the hydrogen bonds played major role in the reaction. Furthermore, the displacement experiments indicated that MPA-Gd could bind to the site Ⅱof HSA.
文摘With the cultural myth that science can only determine the way the world "is" (facts), while humanities, social sciences, lawyers, philosophers, and theologians must determine the way the world "ought to be" (values), those in position of global-, national-, and local-political power make major decisions of the use (or non-use) of scientific knowledge and technology. As a result, the human being has created a non-scientifically based cultural environment that is affecting his ability to survive. In effect, cultural evolution is occurring more rapidly than biological evolution that can adapt to the changes brought about in the physical and psycho-social environments. In a pluralistic cultural world, where each society has generated a different view of human nature and different ethical values, the use, misuse, or non-use of scientific and technological advances are derived from these unscientific views of human nature. Since all life depends on limiting interacting environmental and ecological factors, it is imperative that scientific information be used to govern how to minimize irreversible effects on life-sustaining ecological factors, but also scientific information bearing on understanding human nature ought to be integrated into a "global bioethics". While ethical values cannot be directly derived from scientific factors, it is also true that human values or our "ought" cannot be maintained in ignorance or defiance of the facts or the "is".