AIM:To investigate the changes in corneal biomechanics and posterior corneal surface elevation after femtosecond laser-assisted in situ keratomileusis(FS-LASIK).METHODS:Totally 197 eyes of 100 patients who underwent t...AIM:To investigate the changes in corneal biomechanics and posterior corneal surface elevation after femtosecond laser-assisted in situ keratomileusis(FS-LASIK).METHODS:Totally 197 eyes of 100 patients who underwent the FS-LASIK from April 2022 to November 2022 were included.They were divided into three groups according to the ratio of residual corneal stroma thickness/corneal thickness(RCST/CT):Group I(50%≤RCST/CT<55%,63 eyes of 32 patients),Group II(55%≤RCST/CT<60%,67 eyes of 34 patients),and Group III(RCST/CT≥60%,67 eyes of 34 patients).The intraocular pressure(IOP),corneal compensated IOP(IOPcc),corneal hysteresis(CH)and corneal resistance factor(CRF)were measured immediately,1,and 3mo postoperatively by ocular response analyzer(ORA)and the posterior elevation difference(PED)was measured by Pentacam.RESULTS:After operation,IOP,CH,CRF,and PED were statistically different among the three groups(F=12.99,31.148,23.998,all P<0.0001).There was no statistically significant difference in IOPcc among the three groups(F=0.603,P>0.05).The IOP,IOPcc,CH,and CRF were statistical changed after surgery(F=699.635,104.125,308.474,640.145,all P<0.0001).The PED of Group I was significantly higher than that of Group II(P<0.05),and Group II was significantly higher than that of Group III(P<0.05).The PED value of 3mo after surgery decreased in each group compared with 1mo after surgery,but there was no statistical difference(Group I:t=0.82,P=0.41;Group II:t=0.17,P=0.87;Group III:t=1.35,P=0.18).The correlation analysis of corneal biomechanical parameter changes with PED at 1mo and 3mo after surgery showed thatΔIOP,ΔIOPcc,ΔCH,andΔCRF were not correlated with PED value in three groups(P>0.05).CONCLUSION:The smaller the RCST/CT,the greater effect on corneal biomechanics and posterior surface elevation.There is no correlation between changes in corneal biomechanics and posterior corneal surface elevation in the range of RCST/CT≥50%.展开更多
目的:探讨中低度近视前弹力层下激光角膜磨镶术(sub-Bowmans keratomileusis,SBK)及准分子激光原位角膜磨镶术(laser in situkeratomi leusis,LASIK)术后角膜后表面高度的变化。方法:中低度近视患者108例216眼,前瞻性、随机性为其1眼行...目的:探讨中低度近视前弹力层下激光角膜磨镶术(sub-Bowmans keratomileusis,SBK)及准分子激光原位角膜磨镶术(laser in situkeratomi leusis,LASIK)术后角膜后表面高度的变化。方法:中低度近视患者108例216眼,前瞻性、随机性为其1眼行SBK手术,其对侧眼行LASIK手术,术前及术后1wk;1,3,6mo应用Pentacam三维眼前节分析系统检查,分析比较SBK和LASIK两组间各个不同时间点的角膜后表面高度。结果:术后所有患者视力均达到或超过术前矫正视力。经配对t检验,SBK组和LASIK组术前术后,术后各时间段的比较,差异均无统计学意义。各时期两组间角膜后表面高度值比较,差异亦无统计学差异。结论:SBK和LASIK手术对中低度近视患者术后角膜后表面高度无明显影响。展开更多
目的研究准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后角膜后表面高度的改变及其相关影响因素。方法对52例(102眼)近视及近视散光患者施行LASIK手术,分别于术前、术后第1个月、第3个月应用Pentacam眼前节分析系...目的研究准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后角膜后表面高度的改变及其相关影响因素。方法对52例(102眼)近视及近视散光患者施行LASIK手术,分别于术前、术后第1个月、第3个月应用Pentacam眼前节分析系统检测角膜后表面高度的变化。采用SPSS13.0统计软件进行分析,数据之间两两比较应用配对t检验,角膜后表面高度及高度差与其他因素之间的相关性应用Pearson相关分析。结果手术后第1个月和第3个月,角膜后表面高度分别为(7.21±5.60)μm和(7.27±4.98)μm,与手术前比较,差异有统计学意义(t=-4.033,-4.745;P=0.000,0.000);术后第1个月和第3个月角膜后表面高度的差异无统计学意义(t=-0.179,P=0.859)。术后第1个月和第3个月,角膜后表面前移量分别为(1.61±4.19)μm和(1.74±3.67)μm,两者的差异无统计学意义(t=-0.315,P=0.754)。后表面高度变化分别与手术前屈光度、切削量、切削比、RBT、RBT/CCT有明显相关性(P<0.05)。结论LASIK手术后角膜后表面部分前移,但变化量微小。屈光度越高,切削量越多,RBT保留越少,角膜后表面向前膨隆的程度越大。随着时间的延长,角膜后表面高度变化呈稳定趋势。展开更多
文摘AIM:To investigate the changes in corneal biomechanics and posterior corneal surface elevation after femtosecond laser-assisted in situ keratomileusis(FS-LASIK).METHODS:Totally 197 eyes of 100 patients who underwent the FS-LASIK from April 2022 to November 2022 were included.They were divided into three groups according to the ratio of residual corneal stroma thickness/corneal thickness(RCST/CT):Group I(50%≤RCST/CT<55%,63 eyes of 32 patients),Group II(55%≤RCST/CT<60%,67 eyes of 34 patients),and Group III(RCST/CT≥60%,67 eyes of 34 patients).The intraocular pressure(IOP),corneal compensated IOP(IOPcc),corneal hysteresis(CH)and corneal resistance factor(CRF)were measured immediately,1,and 3mo postoperatively by ocular response analyzer(ORA)and the posterior elevation difference(PED)was measured by Pentacam.RESULTS:After operation,IOP,CH,CRF,and PED were statistically different among the three groups(F=12.99,31.148,23.998,all P<0.0001).There was no statistically significant difference in IOPcc among the three groups(F=0.603,P>0.05).The IOP,IOPcc,CH,and CRF were statistical changed after surgery(F=699.635,104.125,308.474,640.145,all P<0.0001).The PED of Group I was significantly higher than that of Group II(P<0.05),and Group II was significantly higher than that of Group III(P<0.05).The PED value of 3mo after surgery decreased in each group compared with 1mo after surgery,but there was no statistical difference(Group I:t=0.82,P=0.41;Group II:t=0.17,P=0.87;Group III:t=1.35,P=0.18).The correlation analysis of corneal biomechanical parameter changes with PED at 1mo and 3mo after surgery showed thatΔIOP,ΔIOPcc,ΔCH,andΔCRF were not correlated with PED value in three groups(P>0.05).CONCLUSION:The smaller the RCST/CT,the greater effect on corneal biomechanics and posterior surface elevation.There is no correlation between changes in corneal biomechanics and posterior corneal surface elevation in the range of RCST/CT≥50%.
文摘目的:探讨中低度近视前弹力层下激光角膜磨镶术(sub-Bowmans keratomileusis,SBK)及准分子激光原位角膜磨镶术(laser in situkeratomi leusis,LASIK)术后角膜后表面高度的变化。方法:中低度近视患者108例216眼,前瞻性、随机性为其1眼行SBK手术,其对侧眼行LASIK手术,术前及术后1wk;1,3,6mo应用Pentacam三维眼前节分析系统检查,分析比较SBK和LASIK两组间各个不同时间点的角膜后表面高度。结果:术后所有患者视力均达到或超过术前矫正视力。经配对t检验,SBK组和LASIK组术前术后,术后各时间段的比较,差异均无统计学意义。各时期两组间角膜后表面高度值比较,差异亦无统计学差异。结论:SBK和LASIK手术对中低度近视患者术后角膜后表面高度无明显影响。
文摘目的研究准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后角膜后表面高度的改变及其相关影响因素。方法对52例(102眼)近视及近视散光患者施行LASIK手术,分别于术前、术后第1个月、第3个月应用Pentacam眼前节分析系统检测角膜后表面高度的变化。采用SPSS13.0统计软件进行分析,数据之间两两比较应用配对t检验,角膜后表面高度及高度差与其他因素之间的相关性应用Pearson相关分析。结果手术后第1个月和第3个月,角膜后表面高度分别为(7.21±5.60)μm和(7.27±4.98)μm,与手术前比较,差异有统计学意义(t=-4.033,-4.745;P=0.000,0.000);术后第1个月和第3个月角膜后表面高度的差异无统计学意义(t=-0.179,P=0.859)。术后第1个月和第3个月,角膜后表面前移量分别为(1.61±4.19)μm和(1.74±3.67)μm,两者的差异无统计学意义(t=-0.315,P=0.754)。后表面高度变化分别与手术前屈光度、切削量、切削比、RBT、RBT/CCT有明显相关性(P<0.05)。结论LASIK手术后角膜后表面部分前移,但变化量微小。屈光度越高,切削量越多,RBT保留越少,角膜后表面向前膨隆的程度越大。随着时间的延长,角膜后表面高度变化呈稳定趋势。
