BACKGROUND Cognitive decline is common among older patients with cardiovascular disease(CVD) and can decrease their self-management abilities. However, the instruments for identifying mild cognitive impairment(MCI) ar...BACKGROUND Cognitive decline is common among older patients with cardiovascular disease(CVD) and can decrease their self-management abilities. However, the instruments for identifying mild cognitive impairment(MCI) are not always feasible in clinical practice. Therefore, this study evaluated whether MCI could be detected using the Japanese version of the Rapid Dementia Screening Test(RDST-J), which is a simple screening tool for identifying cognitive decline.METHODS This retrospective single-center study included patients who were ≥ 65 years old and hospitalized because of CVD.Patients with a pre-hospitalization diagnosis of dementia were excluded. Each patient's cognitive function had been measured at discharge using the RDST-J and the Japanese version of the Montreal Cognitive Assessment(Mo CA-J), which is a standard tool for MCI screening. The correlation between the two scores was evaluated using Spearman's rank correlation coefficient. Receiver operating characteristic(ROC) analysis was also to evaluate whether the RDST-J could identify MCI, which was defined as a Mo CA-J score of ≤ 25 points.RESULTS The study included 78 patients(mean age: 77.2 ± 8.9 years). The RDST-J and Mo CA-J scores were strongly correlated(r = 0.835, P < 0.001). The ROC analysis revealed that an RDST-J score of ≤ 9 points provided 75.4% sensitivity and 95.2% specificity for identifying MCI, with an area under the curve of 0.899(95% CI: 0.835-0.964). The same cut-off value was identified when excluding patients with a high probability of dementia(RDST-J score of ≤ 4 points).CONCLUSIONS The RDST-J may be a simple and effective tool for identifying MCI in older patients with CVD.展开更多
目的基于决策树法构建老年轻度认知障碍患者并发吞咽功能障碍的风险预测模型,以期为临床防治工作提供参考。方法回顾性分析2019年10月至2022年3月在某院治疗的老年轻度认知障碍患者150例的临床资料,按是否发生吞咽功能障碍,将其分为吞...目的基于决策树法构建老年轻度认知障碍患者并发吞咽功能障碍的风险预测模型,以期为临床防治工作提供参考。方法回顾性分析2019年10月至2022年3月在某院治疗的老年轻度认知障碍患者150例的临床资料,按是否发生吞咽功能障碍,将其分为吞咽障碍组和非吞咽障碍组,分析其危险因素,建立决策树模型,并分析预测效能。结果150例老年轻度认知障碍患者中,吞咽功能障碍发生率为28.0%。两组患者在年龄、Fried衰弱评估量表(Fried Frailty Phenotype,FRIED)、Barthel指数(Barthel index,BI)等项目上的差异均有统计学意义(均P<0.05)。Logistic回归分析结果显示,年龄、FRIED评分、BI、吞咽训练、牙齿缺损、用药种类数均为老年轻度认知障碍患者合并吞咽功能障碍的危险因素(P<0.05)。BI评分是老年轻度认知障碍患者合并吞咽功能障碍最为重要的影响因素。决策树模型预测老年轻度认知障碍患者合并吞咽功能障碍的受试者操作特征曲线下面积(area under the curve,AUC)值稍高于Logistic回归模型。结论构建的决策树预测模型对老年轻度认知障碍患者合并吞咽功能障碍具有较好的风险预测价值。展开更多
文摘BACKGROUND Cognitive decline is common among older patients with cardiovascular disease(CVD) and can decrease their self-management abilities. However, the instruments for identifying mild cognitive impairment(MCI) are not always feasible in clinical practice. Therefore, this study evaluated whether MCI could be detected using the Japanese version of the Rapid Dementia Screening Test(RDST-J), which is a simple screening tool for identifying cognitive decline.METHODS This retrospective single-center study included patients who were ≥ 65 years old and hospitalized because of CVD.Patients with a pre-hospitalization diagnosis of dementia were excluded. Each patient's cognitive function had been measured at discharge using the RDST-J and the Japanese version of the Montreal Cognitive Assessment(Mo CA-J), which is a standard tool for MCI screening. The correlation between the two scores was evaluated using Spearman's rank correlation coefficient. Receiver operating characteristic(ROC) analysis was also to evaluate whether the RDST-J could identify MCI, which was defined as a Mo CA-J score of ≤ 25 points.RESULTS The study included 78 patients(mean age: 77.2 ± 8.9 years). The RDST-J and Mo CA-J scores were strongly correlated(r = 0.835, P < 0.001). The ROC analysis revealed that an RDST-J score of ≤ 9 points provided 75.4% sensitivity and 95.2% specificity for identifying MCI, with an area under the curve of 0.899(95% CI: 0.835-0.964). The same cut-off value was identified when excluding patients with a high probability of dementia(RDST-J score of ≤ 4 points).CONCLUSIONS The RDST-J may be a simple and effective tool for identifying MCI in older patients with CVD.
文摘目的基于决策树法构建老年轻度认知障碍患者并发吞咽功能障碍的风险预测模型,以期为临床防治工作提供参考。方法回顾性分析2019年10月至2022年3月在某院治疗的老年轻度认知障碍患者150例的临床资料,按是否发生吞咽功能障碍,将其分为吞咽障碍组和非吞咽障碍组,分析其危险因素,建立决策树模型,并分析预测效能。结果150例老年轻度认知障碍患者中,吞咽功能障碍发生率为28.0%。两组患者在年龄、Fried衰弱评估量表(Fried Frailty Phenotype,FRIED)、Barthel指数(Barthel index,BI)等项目上的差异均有统计学意义(均P<0.05)。Logistic回归分析结果显示,年龄、FRIED评分、BI、吞咽训练、牙齿缺损、用药种类数均为老年轻度认知障碍患者合并吞咽功能障碍的危险因素(P<0.05)。BI评分是老年轻度认知障碍患者合并吞咽功能障碍最为重要的影响因素。决策树模型预测老年轻度认知障碍患者合并吞咽功能障碍的受试者操作特征曲线下面积(area under the curve,AUC)值稍高于Logistic回归模型。结论构建的决策树预测模型对老年轻度认知障碍患者合并吞咽功能障碍具有较好的风险预测价值。
