BACKGROUND In December 2019,an ongoing outbreak of coronavirus disease 2019(COVID-19)was first identified in Wuhan,China.The characteristics of COVID-19 patients treated in local hospitals in Wuhan are not fully repre...BACKGROUND In December 2019,an ongoing outbreak of coronavirus disease 2019(COVID-19)was first identified in Wuhan,China.The characteristics of COVID-19 patients treated in local hospitals in Wuhan are not fully representative of patients outside Wuhan.Therefore,it is highly essential to analyze the epidemiological and clinical characteristics of COVID-19 in areas outside Wuhan or Hubei Province.To date,a limited number of studies have concentrated on the epidemiological and clinical characteristics of COVID-19 patients with different genders,clinical classification,and with or without basic diseases.AIM To study the epidemiological and clinical characteristics of COVID-19 patients in Hengyang(China)and provide a reliable reference for the prevention and control of COVID-19.METHODS From January 16 to March 2,2020,a total of 48 confirmed cases of COVID-19 were reported in Hengyang,and those cases were included in this study.The diagnostic criteria,clinical classification,and discharge standard related to COVID-19 were in line with the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia(Trial Version 7)released by National Health Commission and National Administration of Traditional Chinese Medicine.The presence of SARS-CoV-2 in pharyngeal swab specimens was detected by quantitative reverse transcription polymerase chain reaction.All the data were imported into the excel worksheet and statistically analyzed by using SPSS 25.0 software.RESULTS A total of 48 cases of COVID-19 were collected,of which 1 was mild,38 were moderate,and 9 were severe.It was unveiled that there were 31(64.6%)male patients and 17(35.4%)female patients,with a female-to-male ratio of 1.82:1.The range of age of patients with COVID-19 was dominantly 30-49 years old[25(52.1%)of 48],followed by those aged over 60 years old[11(22.9%)].Besides,29.2%(14 of 48)of patients had basic diseases,and 57.2%(8 of 14)of patients with basic diseases were aged over 60 years old.The occupations of 48 COVID-19 patients were mainly farmers working in agricultural production[15(31.5%)of 48],rural migrant workers from Hengyang to Wuhan[15(31.5%)],and service workers operating in the service sector[8(16.7%)].The mean latent period was 6.86±3.57 d,and the median was 7[interquartile range(IQR):4-9]d.The mean time from onset of symptoms to the first physician visit was 3.38±2.98(95%CI:2.58-9.18)d,with a median of 2(IQR:1-5)d,and the mean time from hospital admission to confirmed diagnosis was 2.29±2.11(95%CI:1.18-6.42)d,with a median of 2(IQR:1-3)d.The main symptoms were fever[43(89.6%)of 48],cough and expectoration[41(85.4%)],fatigue[22(45.8%)],and chills[22(45.8%)].Other symptoms included poor appetite[13(27.1%)],sore throat[9(18.8%)],dyspnea[9(18.8%)],diarrhea[7(14.6%)],dizziness[5(10.4%)],headache[5(10.4%)],muscle pain[5(10.4%)],nausea and vomiting[4(8.3%)],hemoptysis[4(8.3%)],and runny nose[1(2.1%)].The numbers of peripheral blood leukocytes,lymphocytes,and eosinophils were significantly reduced in the majority of the patients.The levels of C-reactive protein,fibrinogen,blood glucose,lactate dehydrogenase,Ddimer,alanine aminotransferase(ALT),aspartate aminotransferase(AST),gamma-glutamyl transferase(γ-GT),myoglobin(MB),and creatine kinase(CK)were increased in 64.6%,44.7%,43.2%,37.0%,29.5%,22.9%,20.8%,21.6%,13.6%,and 12.8%of patients,respectively.The incidence of ALT elevation in male patients was remarkably higher than that in females(P<0.01),while the incidences of AST,CK,and blood glucose elevations in severe patients were remarkably higher than those in moderate patients(P<0.05,respectively).Except for the mild patients,chest computed tomography showed characteristic pulmonary lesions.All the patients received antiviral drugs,38(79.2%)accepted traditional Chinese medicine,and 2(4.2%)received treatment of human umbilical-cord mesenchymal stem cells.On March 2,2020,48 patients with COVID-19 were all cured and discharged.CONCLUSION Based on our results,patients with COVID-19 often have multiple organ dysfunction or damage.The incidences of ALT elevation in males,and AST,CK,and blood glucose elevations in severe patients are remarkably higher.展开更多
This paper discusses the Cretaceous-Tertiary magnetic polarity sequence of the the Hengyang Basin on the basis of magnetostratigraphic study. The age of each stratigraphic unit has been determined with the magnetic po...This paper discusses the Cretaceous-Tertiary magnetic polarity sequence of the the Hengyang Basin on the basis of magnetostratigraphic study. The age of each stratigraphic unit has been determined with the magnetic polarity time scale combined with 39Ar/40Ar dating, thus providing evidence for determining the geological ages of different formations. The authors assign the age of the Dongjing Formation of the Hengyang Basin to Early Cretaceous, the Shenhuangshan Formation to Early-Late Cretaceous, the Daijiaping Formation to Late Cretaceous, and the Dongtang and Xialiushi formations to Palaeocene.展开更多
[Objective]The study aimed to assess the vulnerability of agricultural eco-environment of hilly basin area in the middle of Hunan Province.[Method]Taking Hengyang basin as an example,we firstly chose 13 indicators fro...[Objective]The study aimed to assess the vulnerability of agricultural eco-environment of hilly basin area in the middle of Hunan Province.[Method]Taking Hengyang basin as an example,we firstly chose 13 indicators from natural,social and economic subsystem to assess the vulnerability of agricultural eco-environment in hilly basin area in the middle of Hunan Province.Afterwards,by using principal component analysis,we calculated the weight of each indicator and the vulnerability of agricultural eco-environment of seven regions,finally analyzed the spatial distribution of agricultural eco-environment vulnerability.[Result]The weight of farmers' net income per capita was up to 0.140,followed by forest coverage(0.137).Among the seven counties,the vulnerability of agricultural eco-environment was primarily moderate,while Hengnan County had the highest vulnerability,followed by Hengyang County,and their vulnerability was extremely serious.In addition,Leiyang City was the minimum fragile region,namely slightly fragile region.In general,the vulnerability of peripheral counties was lower than that of central counties.[Conclusion]The research could provide scientific references for the restoration and reconstruction of agro-ecological environment as well as the establishment of agricultural production decisions.展开更多
基金Supported by the Novel Coronavirus Pneumonia Emergency Project of University of South China,No.2020-15 and No.2020-25the Hengyang Science and Technology Plan Project-Basic Research Project of Prevention and Treatment of the Novel Coronavirus Pneumonia,No.202010031577+2 种基金the Scientific Research Project of Hunan Provincial Health and Family Planning Commission,No.A2017015the Natural Science Foundation of Hunan Province,China,No.2016JJ5010the National Natural Science Foundation of China,No.81373465.
文摘BACKGROUND In December 2019,an ongoing outbreak of coronavirus disease 2019(COVID-19)was first identified in Wuhan,China.The characteristics of COVID-19 patients treated in local hospitals in Wuhan are not fully representative of patients outside Wuhan.Therefore,it is highly essential to analyze the epidemiological and clinical characteristics of COVID-19 in areas outside Wuhan or Hubei Province.To date,a limited number of studies have concentrated on the epidemiological and clinical characteristics of COVID-19 patients with different genders,clinical classification,and with or without basic diseases.AIM To study the epidemiological and clinical characteristics of COVID-19 patients in Hengyang(China)and provide a reliable reference for the prevention and control of COVID-19.METHODS From January 16 to March 2,2020,a total of 48 confirmed cases of COVID-19 were reported in Hengyang,and those cases were included in this study.The diagnostic criteria,clinical classification,and discharge standard related to COVID-19 were in line with the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia(Trial Version 7)released by National Health Commission and National Administration of Traditional Chinese Medicine.The presence of SARS-CoV-2 in pharyngeal swab specimens was detected by quantitative reverse transcription polymerase chain reaction.All the data were imported into the excel worksheet and statistically analyzed by using SPSS 25.0 software.RESULTS A total of 48 cases of COVID-19 were collected,of which 1 was mild,38 were moderate,and 9 were severe.It was unveiled that there were 31(64.6%)male patients and 17(35.4%)female patients,with a female-to-male ratio of 1.82:1.The range of age of patients with COVID-19 was dominantly 30-49 years old[25(52.1%)of 48],followed by those aged over 60 years old[11(22.9%)].Besides,29.2%(14 of 48)of patients had basic diseases,and 57.2%(8 of 14)of patients with basic diseases were aged over 60 years old.The occupations of 48 COVID-19 patients were mainly farmers working in agricultural production[15(31.5%)of 48],rural migrant workers from Hengyang to Wuhan[15(31.5%)],and service workers operating in the service sector[8(16.7%)].The mean latent period was 6.86±3.57 d,and the median was 7[interquartile range(IQR):4-9]d.The mean time from onset of symptoms to the first physician visit was 3.38±2.98(95%CI:2.58-9.18)d,with a median of 2(IQR:1-5)d,and the mean time from hospital admission to confirmed diagnosis was 2.29±2.11(95%CI:1.18-6.42)d,with a median of 2(IQR:1-3)d.The main symptoms were fever[43(89.6%)of 48],cough and expectoration[41(85.4%)],fatigue[22(45.8%)],and chills[22(45.8%)].Other symptoms included poor appetite[13(27.1%)],sore throat[9(18.8%)],dyspnea[9(18.8%)],diarrhea[7(14.6%)],dizziness[5(10.4%)],headache[5(10.4%)],muscle pain[5(10.4%)],nausea and vomiting[4(8.3%)],hemoptysis[4(8.3%)],and runny nose[1(2.1%)].The numbers of peripheral blood leukocytes,lymphocytes,and eosinophils were significantly reduced in the majority of the patients.The levels of C-reactive protein,fibrinogen,blood glucose,lactate dehydrogenase,Ddimer,alanine aminotransferase(ALT),aspartate aminotransferase(AST),gamma-glutamyl transferase(γ-GT),myoglobin(MB),and creatine kinase(CK)were increased in 64.6%,44.7%,43.2%,37.0%,29.5%,22.9%,20.8%,21.6%,13.6%,and 12.8%of patients,respectively.The incidence of ALT elevation in male patients was remarkably higher than that in females(P<0.01),while the incidences of AST,CK,and blood glucose elevations in severe patients were remarkably higher than those in moderate patients(P<0.05,respectively).Except for the mild patients,chest computed tomography showed characteristic pulmonary lesions.All the patients received antiviral drugs,38(79.2%)accepted traditional Chinese medicine,and 2(4.2%)received treatment of human umbilical-cord mesenchymal stem cells.On March 2,2020,48 patients with COVID-19 were all cured and discharged.CONCLUSION Based on our results,patients with COVID-19 often have multiple organ dysfunction or damage.The incidences of ALT elevation in males,and AST,CK,and blood glucose elevations in severe patients are remarkably higher.
文摘This paper discusses the Cretaceous-Tertiary magnetic polarity sequence of the the Hengyang Basin on the basis of magnetostratigraphic study. The age of each stratigraphic unit has been determined with the magnetic polarity time scale combined with 39Ar/40Ar dating, thus providing evidence for determining the geological ages of different formations. The authors assign the age of the Dongjing Formation of the Hengyang Basin to Early Cretaceous, the Shenhuangshan Formation to Early-Late Cretaceous, the Daijiaping Formation to Late Cretaceous, and the Dongtang and Xialiushi formations to Palaeocene.
基金Supported by the Cultural Geography Project of Key Subject Construction of Hunan Province,China (05JJ40062)Project of Innovative Team Construction about "Resource and Environmental Management and Regional Sustainable Development" in Higher Education of Hunan Province,China
文摘[Objective]The study aimed to assess the vulnerability of agricultural eco-environment of hilly basin area in the middle of Hunan Province.[Method]Taking Hengyang basin as an example,we firstly chose 13 indicators from natural,social and economic subsystem to assess the vulnerability of agricultural eco-environment in hilly basin area in the middle of Hunan Province.Afterwards,by using principal component analysis,we calculated the weight of each indicator and the vulnerability of agricultural eco-environment of seven regions,finally analyzed the spatial distribution of agricultural eco-environment vulnerability.[Result]The weight of farmers' net income per capita was up to 0.140,followed by forest coverage(0.137).Among the seven counties,the vulnerability of agricultural eco-environment was primarily moderate,while Hengnan County had the highest vulnerability,followed by Hengyang County,and their vulnerability was extremely serious.In addition,Leiyang City was the minimum fragile region,namely slightly fragile region.In general,the vulnerability of peripheral counties was lower than that of central counties.[Conclusion]The research could provide scientific references for the restoration and reconstruction of agro-ecological environment as well as the establishment of agricultural production decisions.
