BACKGROUND Primary hepatic leiomyosarcoma(PHL)is a rare malignant tumor and has non-specific clinical manifestations and imaging characteristics,making preoperative diagnosis challenging.Here,we report a case of PHL p...BACKGROUND Primary hepatic leiomyosarcoma(PHL)is a rare malignant tumor and has non-specific clinical manifestations and imaging characteristics,making preoperative diagnosis challenging.Here,we report a case of PHL presenting primarily with fever,with computed tomography imaging showing a thick-walled hepatic lesion with low-density areas,resembling liver abscess.CASE SUMMARY The patient was a 34-year-old woman who presented with right upper abdominal pain and fever over 4 days before admission.Based on the patient’s medical history,laboratory examinations,and imaging examinations,liver abscess was suspected.Mesenchymal tumor was diagnosed by percutaneous liverbiopsy and partial hepatectomy was performed.Postoperative pathology revealed PHL.The patient is currently undergoing intravenous chemotherapy with the AD regimen and shows no signs of recurrence.CONCLUSION When there is a thick wall and rich blood supply in the hepatic lesion with a large proportion of uneven low-density areas,PHL should be considered.展开更多
BACKGROUND Primary hepatic leiomyosarcoma is a very rare entity that originates from smooth muscle.Preoperative diagnosis requires a high degree of suspicion due to atypical clinical presentation and non-specific imag...BACKGROUND Primary hepatic leiomyosarcoma is a very rare entity that originates from smooth muscle.Preoperative diagnosis requires a high degree of suspicion due to atypical clinical presentation and non-specific imaging features.CASE SUMMARY We report the case of a 42-year-old man,with no relevant past medical history,accidentally diagnosed with a nodular liver lesion on a routine abdominal ultrasound.Liver function tests and hematology parameters as well as tumor markers were normal.A contrast-enhanced abdominal computed tomography scan revealed a heterogenous hepatic lesion measuring 40 mm 30 mm,adjacent to the left branch of the portal vein and the round ligament.Due to the unclear diagnosis,the patient underwent surgical resection.Histopathological and immunohistochemical examinations confirmed complete(R0)resection of a hepatic leiomyosarcoma.The patient remains without any signs of tumor recurrence for more than 2 years.CONCLUSION We report a rare case of accidentally diagnosed primary hepatic leiomyosarcoma originating from the portal vein or the round ligament.Although this tumor has aggressive metastatic potential,a tumor-free resection margin is essential to improve survival.展开更多
Primary malignant liver mesenchymal tumor is a rare condition defined as a tumor with vascular, fibrous, adi-pose, and other mesenchymal tissue differentiation. We report a case of primary malignant liver mesenchymal ...Primary malignant liver mesenchymal tumor is a rare condition defined as a tumor with vascular, fibrous, adi-pose, and other mesenchymal tissue differentiation. We report a case of primary malignant liver mesenchymal tumor in a 51-year-old male with anemia, weight loss and hepatomegaly. Finally unconventional liver biopsy and histological manifestation led to the definitive diag-nosis.展开更多
基金Supported by the Lishui City Key Research and Development Project,No.2022ZDYF08.
文摘BACKGROUND Primary hepatic leiomyosarcoma(PHL)is a rare malignant tumor and has non-specific clinical manifestations and imaging characteristics,making preoperative diagnosis challenging.Here,we report a case of PHL presenting primarily with fever,with computed tomography imaging showing a thick-walled hepatic lesion with low-density areas,resembling liver abscess.CASE SUMMARY The patient was a 34-year-old woman who presented with right upper abdominal pain and fever over 4 days before admission.Based on the patient’s medical history,laboratory examinations,and imaging examinations,liver abscess was suspected.Mesenchymal tumor was diagnosed by percutaneous liverbiopsy and partial hepatectomy was performed.Postoperative pathology revealed PHL.The patient is currently undergoing intravenous chemotherapy with the AD regimen and shows no signs of recurrence.CONCLUSION When there is a thick wall and rich blood supply in the hepatic lesion with a large proportion of uneven low-density areas,PHL should be considered.
文摘BACKGROUND Primary hepatic leiomyosarcoma is a very rare entity that originates from smooth muscle.Preoperative diagnosis requires a high degree of suspicion due to atypical clinical presentation and non-specific imaging features.CASE SUMMARY We report the case of a 42-year-old man,with no relevant past medical history,accidentally diagnosed with a nodular liver lesion on a routine abdominal ultrasound.Liver function tests and hematology parameters as well as tumor markers were normal.A contrast-enhanced abdominal computed tomography scan revealed a heterogenous hepatic lesion measuring 40 mm 30 mm,adjacent to the left branch of the portal vein and the round ligament.Due to the unclear diagnosis,the patient underwent surgical resection.Histopathological and immunohistochemical examinations confirmed complete(R0)resection of a hepatic leiomyosarcoma.The patient remains without any signs of tumor recurrence for more than 2 years.CONCLUSION We report a rare case of accidentally diagnosed primary hepatic leiomyosarcoma originating from the portal vein or the round ligament.Although this tumor has aggressive metastatic potential,a tumor-free resection margin is essential to improve survival.
文摘Primary malignant liver mesenchymal tumor is a rare condition defined as a tumor with vascular, fibrous, adi-pose, and other mesenchymal tissue differentiation. We report a case of primary malignant liver mesenchymal tumor in a 51-year-old male with anemia, weight loss and hepatomegaly. Finally unconventional liver biopsy and histological manifestation led to the definitive diag-nosis.
