Schistosomiasis is an ancient parasitic disease that has afflicted Egyptians since the time of the pharaohs.The disease is caused by lodged schistosome eggs in the host liver,evoking an immune response and leading in ...Schistosomiasis is an ancient parasitic disease that has afflicted Egyptians since the time of the pharaohs.The disease is caused by lodged schistosome eggs in the host liver,evoking an immune response and leading in some patients to the development of hepatic granuloma and fibrosis.Here,we review the epidemiology,immunopathogenesis,and clinical profile of schistosomiasis.This information may aid in the development of more efficacious treatments and improved disease prognosis.展开更多
文摘Schistosomiasis is an ancient parasitic disease that has afflicted Egyptians since the time of the pharaohs.The disease is caused by lodged schistosome eggs in the host liver,evoking an immune response and leading in some patients to the development of hepatic granuloma and fibrosis.Here,we review the epidemiology,immunopathogenesis,and clinical profile of schistosomiasis.This information may aid in the development of more efficacious treatments and improved disease prognosis.