Scalability is an important issue in the design of interconnection networks for massively parallel systems. In this paper a scalable class of interconnection network of Hex-Cell for massively parallel systems is intro...Scalability is an important issue in the design of interconnection networks for massively parallel systems. In this paper a scalable class of interconnection network of Hex-Cell for massively parallel systems is introduced. It is called Multilayer Hex-Cell (MLH). A node addressing scheme and routing algorithm are also presented and discussed. An interesting feature of the proposed MLH is that it maintains a constant network degree regardless of the increase in the network size degree which facilitates modularity in building blocks of scalable systems. The new addressing node scheme makes the proposed routing algorithm simple and efficient in terms of that it needs a minimum number of calculations to reach the destination node. Moreover, the diameter of the proposed MLH is less than Hex-Cell network.展开更多
The hex-cell is one of the interconnection networks used for parallel systems. The main idea of the hex-cell is that there are hexagon cells that construct the network;each one of those cells has six nodes. The perfor...The hex-cell is one of the interconnection networks used for parallel systems. The main idea of the hex-cell is that there are hexagon cells that construct the network;each one of those cells has six nodes. The performance of the network is affected by many factors one of the factors as load balancing. Until the moment of writing of this paper, there is no load balancing algorithm for this network. The proposed algorithm for dynamic load balancing on hex-cell is based on Tree Walking Algorithm (TWA) for load balancing on tree interconnection network and the ring all to all broadcast.展开更多
目的:探讨钙结合蛋白S100A4调节小鼠骨髓源肥大细胞(BMMC)活化的作用。方法:8~10周龄野生型(WT)和S 100 A 4基因敲除(S 100 A 4-/-)C57BL/6健康雄性小鼠各2只,取胫骨与股骨提取骨髓进行骨髓源肥大细胞(BMMC)培养并鉴定;以成熟WT BMMC为...目的:探讨钙结合蛋白S100A4调节小鼠骨髓源肥大细胞(BMMC)活化的作用。方法:8~10周龄野生型(WT)和S 100 A 4基因敲除(S 100 A 4-/-)C57BL/6健康雄性小鼠各2只,取胫骨与股骨提取骨髓进行骨髓源肥大细胞(BMMC)培养并鉴定;以成熟WT BMMC为模型细胞,实验分为S100A4蛋白处理组(1500μg/L S100A4蛋白)和磷酸盐缓冲液(PBS)对照组(S100A4蛋白等量体积PBS),分别于培养第1、2及3周采用甲苯胺蓝染色鉴定小鼠成熟BMMC,采用化学发光法检测各组小鼠成熟BMMC中β-氨基己糖苷酶(β-hex)的吸光度(OD),采用流式细胞术检测各组小鼠成熟BMMC的S100A4蛋白表达和白细胞介素-5(IL-5)、白细胞介素-6(IL-6)、白细胞介素-13(IL-13)及肿瘤坏死因子-α(TNF-α)的荧光强度并计算相对荧光指数(rFI);以成熟WT和S 100 A 4-/-BMMC为模型细胞,实验分为WT离子霉素(ION)处理组(1500μg/L ION)、WT PBS对照组(ION等量体积PBS)、S 100 A 4-/-ION处理组(1500μg/L ION)及S 100 A 4-/-PBS对照组(ION等量体积PBS),采用化学发光法检测各组小鼠成熟BMMC中β-hex的吸光度(OD)。结果:BMMC培养至3周时基本成熟,并表达S100A4蛋白;S100A4蛋白处理组成熟BMMC中β-hex、IL-5、IL-6、IL-13及TNF-α水平高于PBS对照组(P<0.05或P<0.01);WT ION处理组成熟BMMCβ-hex、IL-5、IL-6、IL-13及TNF-α水平高于WT PBS对照组(P<0.01),S 100 A 4-/-ION处理组成熟BMMC中β-hex、IL-5及IL-6明显高于S 100 A 4-/-PBS对照组(P<0.05),S 100 A 4-/-ION处理组成熟BMMC中β-hex、IL-5、IL-6、IL-13及TNF-α水平均低于WT ION处理组(P<0.05)。结论:S100A4蛋白能够直接诱导成熟BMMC活化,S 100 A 4基因的缺失可抑制成熟BMMC活化及炎性因子的产生。展开更多
文摘Scalability is an important issue in the design of interconnection networks for massively parallel systems. In this paper a scalable class of interconnection network of Hex-Cell for massively parallel systems is introduced. It is called Multilayer Hex-Cell (MLH). A node addressing scheme and routing algorithm are also presented and discussed. An interesting feature of the proposed MLH is that it maintains a constant network degree regardless of the increase in the network size degree which facilitates modularity in building blocks of scalable systems. The new addressing node scheme makes the proposed routing algorithm simple and efficient in terms of that it needs a minimum number of calculations to reach the destination node. Moreover, the diameter of the proposed MLH is less than Hex-Cell network.
文摘The hex-cell is one of the interconnection networks used for parallel systems. The main idea of the hex-cell is that there are hexagon cells that construct the network;each one of those cells has six nodes. The performance of the network is affected by many factors one of the factors as load balancing. Until the moment of writing of this paper, there is no load balancing algorithm for this network. The proposed algorithm for dynamic load balancing on hex-cell is based on Tree Walking Algorithm (TWA) for load balancing on tree interconnection network and the ring all to all broadcast.
文摘目的:探讨钙结合蛋白S100A4调节小鼠骨髓源肥大细胞(BMMC)活化的作用。方法:8~10周龄野生型(WT)和S 100 A 4基因敲除(S 100 A 4-/-)C57BL/6健康雄性小鼠各2只,取胫骨与股骨提取骨髓进行骨髓源肥大细胞(BMMC)培养并鉴定;以成熟WT BMMC为模型细胞,实验分为S100A4蛋白处理组(1500μg/L S100A4蛋白)和磷酸盐缓冲液(PBS)对照组(S100A4蛋白等量体积PBS),分别于培养第1、2及3周采用甲苯胺蓝染色鉴定小鼠成熟BMMC,采用化学发光法检测各组小鼠成熟BMMC中β-氨基己糖苷酶(β-hex)的吸光度(OD),采用流式细胞术检测各组小鼠成熟BMMC的S100A4蛋白表达和白细胞介素-5(IL-5)、白细胞介素-6(IL-6)、白细胞介素-13(IL-13)及肿瘤坏死因子-α(TNF-α)的荧光强度并计算相对荧光指数(rFI);以成熟WT和S 100 A 4-/-BMMC为模型细胞,实验分为WT离子霉素(ION)处理组(1500μg/L ION)、WT PBS对照组(ION等量体积PBS)、S 100 A 4-/-ION处理组(1500μg/L ION)及S 100 A 4-/-PBS对照组(ION等量体积PBS),采用化学发光法检测各组小鼠成熟BMMC中β-hex的吸光度(OD)。结果:BMMC培养至3周时基本成熟,并表达S100A4蛋白;S100A4蛋白处理组成熟BMMC中β-hex、IL-5、IL-6、IL-13及TNF-α水平高于PBS对照组(P<0.05或P<0.01);WT ION处理组成熟BMMCβ-hex、IL-5、IL-6、IL-13及TNF-α水平高于WT PBS对照组(P<0.01),S 100 A 4-/-ION处理组成熟BMMC中β-hex、IL-5及IL-6明显高于S 100 A 4-/-PBS对照组(P<0.05),S 100 A 4-/-ION处理组成熟BMMC中β-hex、IL-5、IL-6、IL-13及TNF-α水平均低于WT ION处理组(P<0.05)。结论:S100A4蛋白能够直接诱导成熟BMMC活化,S 100 A 4基因的缺失可抑制成熟BMMC活化及炎性因子的产生。