New hexalobine type alkaloid,5-(200,300-epoxy-300-methylbutyl)-3-(30-hydroxy-30-methyl-10-acetyloxy-but-20-yl)indole(1)alongside the known hexalobines 3-(20,30-dihydroxy-30-methylbutyl)-5-(300-methylcrotonoyl)indole(2...New hexalobine type alkaloid,5-(200,300-epoxy-300-methylbutyl)-3-(30-hydroxy-30-methyl-10-acetyloxy-but-20-yl)indole(1)alongside the known hexalobines 3-(20,30-dihydroxy-30-methylbutyl)-5-(300-methylcrotonoyl)indole(2),3,5-hexalobine C(3)and 3,5-hexalobine D(4)were isolated from fruits of Hexalobus monopetalus.Compounds 3 and 4 exhibited antifungal activity against Candida albicans.展开更多
基金The Norwegian Agency for International Development(NORAD)through the NORAD Chemistry Project is appreciated for supporting this work through a scholarship grant to H.M.MThe National Institute for Medical Research(NIMR),The Department of Chemistry at the University of Dar es Salaam in Tanzaniathe Department of Pharmaceutical Chemistry in the Institute of Pharmacy at Erlangen University in Germany are thanked for supporting the research project.
文摘New hexalobine type alkaloid,5-(200,300-epoxy-300-methylbutyl)-3-(30-hydroxy-30-methyl-10-acetyloxy-but-20-yl)indole(1)alongside the known hexalobines 3-(20,30-dihydroxy-30-methylbutyl)-5-(300-methylcrotonoyl)indole(2),3,5-hexalobine C(3)and 3,5-hexalobine D(4)were isolated from fruits of Hexalobus monopetalus.Compounds 3 and 4 exhibited antifungal activity against Candida albicans.
