AIM: To investigate the possible relationship between the influencing factors occurring before and during birth in full-term infants and the outcome of retinopathy. METHODS: Totally 816 full-term infants admitted in t...AIM: To investigate the possible relationship between the influencing factors occurring before and during birth in full-term infants and the outcome of retinopathy. METHODS: Totally 816 full-term infants admitted in the neonate intensive unit of Boai Hospital of Zhongshan between 1 May, 2008 and 30 June, 2011 were included in the study. Fundus examination was performed and evaluated individually on them at the age of 48 hours after delivery, 2 weeks and 1 month. Some possible risk factors happening prenatally or during delivery such as pregnant related hypertension, placenta previa, placental abruption etc, as well as some neonatal risk factors such as neonatal asphyxia, hypoxic-ischemic encephalopathy (HIE), low birth weight etc, were recorded and evacuated. Then the effect of the risk factors of full-term infants on retinopathy was studied. RESULTS: The incidence of retinal hemorrhage of full-term infants with prenatal pregnant related hypertension (PRH) of the mother (43.6%) was significantly higher than that of full-term infants without (8.0%). (P<0.001). The incidence of retinal hemorrhage of full-term infants with neonatal asphyxia and /or hypoxic-ischemic encephalopathy (HIE)(29.3%) was significantly higher than that of those without (15.7%), but correlation was not found between the severity of retina hemorrhage and the degree of hypoxic disease. A pale color of optic disc was associated with a low birth weight of full-term infant. Full-term infants with birth weigh-less than 2500g had a significant higher incidence of retinopathy than those with birth weight equal or more than 2500g( P<0.001). CONCLUSION: The main influencing factors which lead to retinopathy of high risk full-term infants are prenatal factors such as PRH, and some neonatal risk factors such as asphyxia, hypoxic-ischemic encephalopathy, and low birth weight.展开更多
The study assessed the effects of supplementary feeding over 180 consecutive days on iron status of infants and toddlers at six tea plantation in West Java, Indonesia. The design used was a clinical trial: two eohorts...The study assessed the effects of supplementary feeding over 180 consecutive days on iron status of infants and toddlers at six tea plantation in West Java, Indonesia. The design used was a clinical trial: two eohorts (i.e., 12 and 18 months old children) and three treatment groups (i.e., energy + micronutrient, micronutrient alone, and placebo) per cohort. Every day except Sunday, the infants attended day-care centers. Twenty four centers and 136 infants were selected. The infants were screened for weight and length and those meeting the criteria (i.e., <-1 SD of length-for-age, and between -1 and -2 SD of weight-for-length of the NCHS reference) were included. The experimental unit was the day-care centers (DCC), where each DCC was randomly assigned to one of the three treatment. As expected, groups of energy + micronutrient and micronutrient alone of the 12 months cohort experienced a significant upward shift in hemoglobin, ferritin and TS and a downward change in FEP, while the values for the group of placebo remain about the same as at base line. In the first 6 month of treatments, the ANOVA for each iron indicator yielded significant main effects of treatment (P<0.01) and for Hb with (P =0.059) on 12 months cohort. On the other hand, the main effects of treatment on hemoglobin, TS, ferritin and FEP were not significant for the 18 months cohort. In the second 6 month of treatments, the only significant of the treatment effect (P<0.01) was in serum ferritin on 18-month cohort. Under these circumstances, energy has a positive role in improving iron stores. It is likely that the equilibrium of hemoglobin and each iron indicators were reached in 6 months of treatment except ferritin still continued to increase up to 12 month. The effects of treatment on the improvement of iron status was stronger in 12 months than in 18 months展开更多
目的观察靳三针联合早期目标-活动-运动环境训练对脑性瘫痪高危儿的临床疗效,为治疗脑性瘫痪高危儿提供新的治疗思路。方法本研究为随机对照试验。选取西安市人民医院儿童保健科2021年5月至2023年1月期间收治的80例脑性瘫痪高危儿,按照...目的观察靳三针联合早期目标-活动-运动环境训练对脑性瘫痪高危儿的临床疗效,为治疗脑性瘫痪高危儿提供新的治疗思路。方法本研究为随机对照试验。选取西安市人民医院儿童保健科2021年5月至2023年1月期间收治的80例脑性瘫痪高危儿,按照随机数字表法分为观察组(40例)和对照组(40例)。观察组男19例,女21例,月龄(4.09±0.89)个月;对照组男22例,女18例,月龄(4.25±0.74)个月。对照组患儿接受基础康复和早期目标-活动-运动环境治疗,基础康复是以神经发育学治疗为主的Rood疗法和Bobath疗法,每次40 min,1次/d,5次/周,共6个月;观察组在对照组治疗基础上采用靳三针治疗,每隔1日针刺1次,每周针刺3次,每3个月为1个疗程,治疗2个疗程后观察疗效。观察两组干预前后粗大运动功能评估量表(Gross Motor Function Measure,GMFM)、精细运动功能评估量表(Fine Motor Function Measure,FMFM)、Gesell发育诊断量表(Gesell Developmental DiagnosisScale,GDDS)得分的差异,常规随访观察患儿的发育状况。行t检验、χ^(2)检验。结果治疗前,两组患儿的GMFM、FMFM、适应性行为、语言评分比较,差异均无统计学意义(均P>0.05)。治疗3、6个月后,观察组的GMFM和FMFM评分分别为(39.29±3.90)分、(49.79±3.16)分、(16.83±3.57)分、(25.59±4.11)分,高于对照组的(34.25±4.08)分、(45.69±3.17)分、(13.73±3.44)分、(19.34±3.54)分,差异均有统计学意义(t=5.648、5.793、3.955、7.287,均P<0.001);观察组的适应性行为和语言得分分别为(57.33±3.90)分、(69.72±4.76)分、(62.86±4.38)分、(68.19±3.89)分,高于对照组的(55.22±4.08)分、(65.21±4.17)分、(58.44±4.74)分、(63.84±3.56分),差异均有统计学意义(t=2.364、4.507、4.331、5.217,均P<0.05)。在校正胎龄为12月龄时,观察组和对照组发育正常比例分别为85.00%(34/40)、60.00%(24/40),两组比较差异有统计学意义(χ^(2)=6.270,P=0.012)。结论靳三针联合早期目标-活动-运动环境训练对提高脑性瘫痪高危儿的运动和认知能力有明显的促进作用,对改善其生长发育具有重要意义。展开更多
Objective: Measure the effects of Early Intervention ad modum Katona (EI-K) in high-risk premature infants by means of clinical, neurobehavioral, and neurophysiologic tests. Method: We used the Amiel-Tison neurologic ...Objective: Measure the effects of Early Intervention ad modum Katona (EI-K) in high-risk premature infants by means of clinical, neurobehavioral, and neurophysiologic tests. Method: We used the Amiel-Tison neurologic examination, the Bayley Scale of Infant Behavior, and electroencephalography (EEG) recordings at 42 weeks of conceptional age, and after 6 months of treatment EI-K (n = 14) and compared these results with those of a group of infants without early intervention (nEI) (n = 11). Results: We found better performance of infants in EI-K than nEI group after 6 months of treatment in neurologic and behavioral examination measurements, but found no differences in EEG comparisons. Conclusion: Our data suggest significant benefit of the use of EI-K program over n-EI in the neurologic and neurobe-havior examinations of premature infants after 6 months of age.展开更多
早产儿视网膜病(retinopathy of prematurity,ROP)是早产儿的严重并发症之一,严重者可致视网膜脱离甚至失明。ROP病因复杂,多种因素参与及影响了ROP的发生与进展,对其相关危险因素进行研究,有助于ROP的预防及治疗,对提高我国人口质量有...早产儿视网膜病(retinopathy of prematurity,ROP)是早产儿的严重并发症之一,严重者可致视网膜脱离甚至失明。ROP病因复杂,多种因素参与及影响了ROP的发生与进展,对其相关危险因素进行研究,有助于ROP的预防及治疗,对提高我国人口质量有重要意义。目前大量研究显示胎龄小、出生体重低、氧疗、机械通气、贫血、输血、早产儿感染、妊娠期并发症等均是ROP发生的危险因素,本文对这些可能影响ROP发生的相关危险因素进行综述。以期达到对危险因素的早期综合干预,提高ROP的整体防治水平,减少ROP的远期并发症。展开更多
基金Supported by Science Council Grant of Zhongshan City, China (No. 20082A091)
文摘AIM: To investigate the possible relationship between the influencing factors occurring before and during birth in full-term infants and the outcome of retinopathy. METHODS: Totally 816 full-term infants admitted in the neonate intensive unit of Boai Hospital of Zhongshan between 1 May, 2008 and 30 June, 2011 were included in the study. Fundus examination was performed and evaluated individually on them at the age of 48 hours after delivery, 2 weeks and 1 month. Some possible risk factors happening prenatally or during delivery such as pregnant related hypertension, placenta previa, placental abruption etc, as well as some neonatal risk factors such as neonatal asphyxia, hypoxic-ischemic encephalopathy (HIE), low birth weight etc, were recorded and evacuated. Then the effect of the risk factors of full-term infants on retinopathy was studied. RESULTS: The incidence of retinal hemorrhage of full-term infants with prenatal pregnant related hypertension (PRH) of the mother (43.6%) was significantly higher than that of full-term infants without (8.0%). (P<0.001). The incidence of retinal hemorrhage of full-term infants with neonatal asphyxia and /or hypoxic-ischemic encephalopathy (HIE)(29.3%) was significantly higher than that of those without (15.7%), but correlation was not found between the severity of retina hemorrhage and the degree of hypoxic disease. A pale color of optic disc was associated with a low birth weight of full-term infant. Full-term infants with birth weigh-less than 2500g had a significant higher incidence of retinopathy than those with birth weight equal or more than 2500g( P<0.001). CONCLUSION: The main influencing factors which lead to retinopathy of high risk full-term infants are prenatal factors such as PRH, and some neonatal risk factors such as asphyxia, hypoxic-ischemic encephalopathy, and low birth weight.
文摘The study assessed the effects of supplementary feeding over 180 consecutive days on iron status of infants and toddlers at six tea plantation in West Java, Indonesia. The design used was a clinical trial: two eohorts (i.e., 12 and 18 months old children) and three treatment groups (i.e., energy + micronutrient, micronutrient alone, and placebo) per cohort. Every day except Sunday, the infants attended day-care centers. Twenty four centers and 136 infants were selected. The infants were screened for weight and length and those meeting the criteria (i.e., <-1 SD of length-for-age, and between -1 and -2 SD of weight-for-length of the NCHS reference) were included. The experimental unit was the day-care centers (DCC), where each DCC was randomly assigned to one of the three treatment. As expected, groups of energy + micronutrient and micronutrient alone of the 12 months cohort experienced a significant upward shift in hemoglobin, ferritin and TS and a downward change in FEP, while the values for the group of placebo remain about the same as at base line. In the first 6 month of treatments, the ANOVA for each iron indicator yielded significant main effects of treatment (P<0.01) and for Hb with (P =0.059) on 12 months cohort. On the other hand, the main effects of treatment on hemoglobin, TS, ferritin and FEP were not significant for the 18 months cohort. In the second 6 month of treatments, the only significant of the treatment effect (P<0.01) was in serum ferritin on 18-month cohort. Under these circumstances, energy has a positive role in improving iron stores. It is likely that the equilibrium of hemoglobin and each iron indicators were reached in 6 months of treatment except ferritin still continued to increase up to 12 month. The effects of treatment on the improvement of iron status was stronger in 12 months than in 18 months
文摘目的观察靳三针联合早期目标-活动-运动环境训练对脑性瘫痪高危儿的临床疗效,为治疗脑性瘫痪高危儿提供新的治疗思路。方法本研究为随机对照试验。选取西安市人民医院儿童保健科2021年5月至2023年1月期间收治的80例脑性瘫痪高危儿,按照随机数字表法分为观察组(40例)和对照组(40例)。观察组男19例,女21例,月龄(4.09±0.89)个月;对照组男22例,女18例,月龄(4.25±0.74)个月。对照组患儿接受基础康复和早期目标-活动-运动环境治疗,基础康复是以神经发育学治疗为主的Rood疗法和Bobath疗法,每次40 min,1次/d,5次/周,共6个月;观察组在对照组治疗基础上采用靳三针治疗,每隔1日针刺1次,每周针刺3次,每3个月为1个疗程,治疗2个疗程后观察疗效。观察两组干预前后粗大运动功能评估量表(Gross Motor Function Measure,GMFM)、精细运动功能评估量表(Fine Motor Function Measure,FMFM)、Gesell发育诊断量表(Gesell Developmental DiagnosisScale,GDDS)得分的差异,常规随访观察患儿的发育状况。行t检验、χ^(2)检验。结果治疗前,两组患儿的GMFM、FMFM、适应性行为、语言评分比较,差异均无统计学意义(均P>0.05)。治疗3、6个月后,观察组的GMFM和FMFM评分分别为(39.29±3.90)分、(49.79±3.16)分、(16.83±3.57)分、(25.59±4.11)分,高于对照组的(34.25±4.08)分、(45.69±3.17)分、(13.73±3.44)分、(19.34±3.54)分,差异均有统计学意义(t=5.648、5.793、3.955、7.287,均P<0.001);观察组的适应性行为和语言得分分别为(57.33±3.90)分、(69.72±4.76)分、(62.86±4.38)分、(68.19±3.89)分,高于对照组的(55.22±4.08)分、(65.21±4.17)分、(58.44±4.74)分、(63.84±3.56分),差异均有统计学意义(t=2.364、4.507、4.331、5.217,均P<0.05)。在校正胎龄为12月龄时,观察组和对照组发育正常比例分别为85.00%(34/40)、60.00%(24/40),两组比较差异有统计学意义(χ^(2)=6.270,P=0.012)。结论靳三针联合早期目标-活动-运动环境训练对提高脑性瘫痪高危儿的运动和认知能力有明显的促进作用,对改善其生长发育具有重要意义。
文摘Objective: Measure the effects of Early Intervention ad modum Katona (EI-K) in high-risk premature infants by means of clinical, neurobehavioral, and neurophysiologic tests. Method: We used the Amiel-Tison neurologic examination, the Bayley Scale of Infant Behavior, and electroencephalography (EEG) recordings at 42 weeks of conceptional age, and after 6 months of treatment EI-K (n = 14) and compared these results with those of a group of infants without early intervention (nEI) (n = 11). Results: We found better performance of infants in EI-K than nEI group after 6 months of treatment in neurologic and behavioral examination measurements, but found no differences in EEG comparisons. Conclusion: Our data suggest significant benefit of the use of EI-K program over n-EI in the neurologic and neurobe-havior examinations of premature infants after 6 months of age.
文摘早产儿视网膜病(retinopathy of prematurity,ROP)是早产儿的严重并发症之一,严重者可致视网膜脱离甚至失明。ROP病因复杂,多种因素参与及影响了ROP的发生与进展,对其相关危险因素进行研究,有助于ROP的预防及治疗,对提高我国人口质量有重要意义。目前大量研究显示胎龄小、出生体重低、氧疗、机械通气、贫血、输血、早产儿感染、妊娠期并发症等均是ROP发生的危险因素,本文对这些可能影响ROP发生的相关危险因素进行综述。以期达到对危险因素的早期综合干预,提高ROP的整体防治水平,减少ROP的远期并发症。
