Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously anal...Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.展开更多
To improve the agility, dynamics, composability, reusability, and development efficiency restricted by monolithic federation object model （FOM）, a modular FOM is proposed by high level architecture （HLA） evolved p...To improve the agility, dynamics, composability, reusability, and development efficiency restricted by monolithic federation object model （FOM）, a modular FOM is proposed by high level architecture （HLA） evolved product development group. This paper reviews the state-of-the-art of HLA evolved modular FOM. In particular, related concepts, the overall impact on HLA standards, extension principles, and merging processes are discussed. Also permitted and restricted combinations, and merging rules are provided, and the influence on HLA interface specification is given. The comparison between modular FOM and base object model （BOM） is performed to illustrate the importance of their combination. The applications of modular FOM are summarized. Finally, the significance to facilitate compoable simulation both in academia and practice is presented and future directions are pointed out.展开更多
The exploration of building detection plays an important role in urban planning,smart city and military.Aiming at the problem of high overlapping ratio of detection frames for dense building detection in high resoluti...The exploration of building detection plays an important role in urban planning,smart city and military.Aiming at the problem of high overlapping ratio of detection frames for dense building detection in high resolution remote sensing images,we present an effective YOLOv3 framework,corner regression-based YOLOv3(Correg-YOLOv3),to localize dense building accurately.This improved YOLOv3 algorithm establishes a vertex regression mechanism and an additional loss item about building vertex offsets relative to the center point of bounding box.By extending output dimensions,the trained model is able to output the rectangular bounding boxes and the building vertices meanwhile.Finally,we evaluate the performance of the Correg-YOLOv3 on our self-produced data set and provide a comparative analysis qualitatively and quantitatively.The experimental results achieve high performance in precision(96.45%),recall rate(95.75%),F1 score(96.10%)and average precision(98.05%),which were 2.73%,5.4%,4.1%and 4.73%higher than that of YOLOv3.Therefore,our proposed algorithm effectively tackles the problem of dense building detection in high resolution images.展开更多
Scanning ion conductance microscopy（SICM） is an emerging non-destructive surface topography characterization apparatus with nanoscale resolution. However, the low regulating frequency of probe in most existing modul...Scanning ion conductance microscopy（SICM） is an emerging non-destructive surface topography characterization apparatus with nanoscale resolution. However, the low regulating frequency of probe in most existing modulated current based SICM systems increases the system noise, and has difficulty in imaging sample surface with steep height changes. In order to enable SICM to have the capability of imaging surfaces with steep height changes, a novel probe that can be used in the modulated current based bopping mode is designed. The design relies on two piezoelectric ceramics with different travels to separate position adjustment and probe frequency regulation in the Z direction. To fiarther improve the resonant frequency of the probe, the material and the key dimensions for each component of the probe are optimized based on the multi-objective optimization method and the finite element analysis. The optimal design has a resonant frequency of above 10 kHz. To validate the rationality of the designed probe, microstructured grating samples are imaged using the homebuilt modulated current based SICM system. The experimental results indicate that the designed high frequency probe can effectively reduce the spike noise by 26% in the average number of spike noise. The proposed design provides a feasible solution for improving the imaging quality of the existing SICM systems which normally use ordinary probes with relatively low regulating frequency.展开更多
As the distributed interactive simulation technology,the High Level Architecture(HLA)with the common Runtime Infrastructure(RTI)services has been applied to all kinds of simulation and computation areas,w hich has mor...As the distributed interactive simulation technology,the High Level Architecture(HLA)with the common Runtime Infrastructure(RTI)services has been applied to all kinds of simulation and computation areas,w hich has more interoperability and interactivity.Especially,w ith the development of hierarchical RTI softw are technology,the efficiency,flexibility,and levels of resolution etc.can be improved.How ever,updating mechanism for object management in hierarchical RTI can't supply the dynamic object subscription to the simulation operation,specially updating limitation in consistence and synchronization.Therefore,the improvement of update mechanism for object management has been proposed,and the process of w hich has been described.The results of simulation show that the improvement mechanism can achieve better updating rates and latency than traditional mechanism,considering the consistence need.展开更多
战斗部破片群运动参数对弹药毁伤威力评估具有重要的意义。针对破片尺寸较小、背景信息复杂以及破片数据样本少导致的破片检测精度较低的问题,本文提出一种YOLOv5-FD的战斗部破片群目标检测方法。首先,在网络输出端增加微小目标检测层,...战斗部破片群运动参数对弹药毁伤威力评估具有重要的意义。针对破片尺寸较小、背景信息复杂以及破片数据样本少导致的破片检测精度较低的问题,本文提出一种YOLOv5-FD的战斗部破片群目标检测方法。首先,在网络输出端增加微小目标检测层,将原始的三尺度改为四尺度,并在特征融合网络中引入内容感知特征重组(Content Aware ReAssembly of Features,CARAFE)上采样模块替换原有的最近邻插值上采样,减少小目标特征信息损失,提高弱小破片的提取能力。其次,在特征提取网络引入坐标注意力模块(Coordinate Attention,CA),加强对破片特征的提取,弱化背景信息,抑制复杂背景的干扰。最后,在模型训练过程中引入模型不可知元学习方法(Model Agnostic Meta Learning,MAML),达到仅用小样本破片数据集实现较高的检测性能。实验结果表明,YOLOv5-FD破片检测算法在自制破片数据集中,精确率达到了90.5%,召回率达到了85.4%,平均精度mAP_0.5达到了88.2%,与原始YOLOv5s算法相比分别提高了7.1%,7.9%和7.5%,有效提高了破片目标检测准确性。展开更多
基金supported by National Key R&D Program of China(grant no.2022YFC2404201)the Chinese Academy of Sciences Project for Young Scientists in Basic Research(grant no.YSBR067).
文摘Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.
基金supported by the National Natural Science Foundation of China(6067406960574056).
文摘To improve the agility, dynamics, composability, reusability, and development efficiency restricted by monolithic federation object model （FOM）, a modular FOM is proposed by high level architecture （HLA） evolved product development group. This paper reviews the state-of-the-art of HLA evolved modular FOM. In particular, related concepts, the overall impact on HLA standards, extension principles, and merging processes are discussed. Also permitted and restricted combinations, and merging rules are provided, and the influence on HLA interface specification is given. The comparison between modular FOM and base object model （BOM） is performed to illustrate the importance of their combination. The applications of modular FOM are summarized. Finally, the significance to facilitate compoable simulation both in academia and practice is presented and future directions are pointed out.
基金National Natural Science Foundation of China(No.41871305)National Key Research and Development Program of China(No.2017YFC0602204)+2 种基金Fundamental Research Funds for the Central Universities,China University of Geosciences(Wuhan)(No.CUGQY1945)Open Fund of Key Laboratory of Geological Survey and Evaluation of Ministry of Education and the Fundamental Research Funds for the Central Universities(No.GLAB2019ZR02)Open Fund of Laboratory of Urban Land Resources Monitoring and Simulation,Ministry of Natural Resources,China(No.KF-2020-05-068)。
文摘The exploration of building detection plays an important role in urban planning,smart city and military.Aiming at the problem of high overlapping ratio of detection frames for dense building detection in high resolution remote sensing images,we present an effective YOLOv3 framework,corner regression-based YOLOv3(Correg-YOLOv3),to localize dense building accurately.This improved YOLOv3 algorithm establishes a vertex regression mechanism and an additional loss item about building vertex offsets relative to the center point of bounding box.By extending output dimensions,the trained model is able to output the rectangular bounding boxes and the building vertices meanwhile.Finally,we evaluate the performance of the Correg-YOLOv3 on our self-produced data set and provide a comparative analysis qualitatively and quantitatively.The experimental results achieve high performance in precision(96.45%),recall rate(95.75%),F1 score(96.10%)and average precision(98.05%),which were 2.73%,5.4%,4.1%and 4.73%higher than that of YOLOv3.Therefore,our proposed algorithm effectively tackles the problem of dense building detection in high resolution images.
基金Supported by National Natural Science Foundation of China(Grant No.51375363)
文摘Scanning ion conductance microscopy（SICM） is an emerging non-destructive surface topography characterization apparatus with nanoscale resolution. However, the low regulating frequency of probe in most existing modulated current based SICM systems increases the system noise, and has difficulty in imaging sample surface with steep height changes. In order to enable SICM to have the capability of imaging surfaces with steep height changes, a novel probe that can be used in the modulated current based bopping mode is designed. The design relies on two piezoelectric ceramics with different travels to separate position adjustment and probe frequency regulation in the Z direction. To fiarther improve the resonant frequency of the probe, the material and the key dimensions for each component of the probe are optimized based on the multi-objective optimization method and the finite element analysis. The optimal design has a resonant frequency of above 10 kHz. To validate the rationality of the designed probe, microstructured grating samples are imaged using the homebuilt modulated current based SICM system. The experimental results indicate that the designed high frequency probe can effectively reduce the spike noise by 26% in the average number of spike noise. The proposed design provides a feasible solution for improving the imaging quality of the existing SICM systems which normally use ordinary probes with relatively low regulating frequency.
基金Financial Support from New Century Program for Excellent Talents of Ministry of Education of China(NCET-11-1013)Program for Liaoning Innovative Research Team in University(LT2011005)
文摘As the distributed interactive simulation technology,the High Level Architecture(HLA)with the common Runtime Infrastructure(RTI)services has been applied to all kinds of simulation and computation areas,w hich has more interoperability and interactivity.Especially,w ith the development of hierarchical RTI softw are technology,the efficiency,flexibility,and levels of resolution etc.can be improved.How ever,updating mechanism for object management in hierarchical RTI can't supply the dynamic object subscription to the simulation operation,specially updating limitation in consistence and synchronization.Therefore,the improvement of update mechanism for object management has been proposed,and the process of w hich has been described.The results of simulation show that the improvement mechanism can achieve better updating rates and latency than traditional mechanism,considering the consistence need.
文摘战斗部破片群运动参数对弹药毁伤威力评估具有重要的意义。针对破片尺寸较小、背景信息复杂以及破片数据样本少导致的破片检测精度较低的问题,本文提出一种YOLOv5-FD的战斗部破片群目标检测方法。首先,在网络输出端增加微小目标检测层,将原始的三尺度改为四尺度,并在特征融合网络中引入内容感知特征重组(Content Aware ReAssembly of Features,CARAFE)上采样模块替换原有的最近邻插值上采样,减少小目标特征信息损失,提高弱小破片的提取能力。其次,在特征提取网络引入坐标注意力模块(Coordinate Attention,CA),加强对破片特征的提取,弱化背景信息,抑制复杂背景的干扰。最后,在模型训练过程中引入模型不可知元学习方法(Model Agnostic Meta Learning,MAML),达到仅用小样本破片数据集实现较高的检测性能。实验结果表明,YOLOv5-FD破片检测算法在自制破片数据集中,精确率达到了90.5%,召回率达到了85.4%,平均精度mAP_0.5达到了88.2%,与原始YOLOv5s算法相比分别提高了7.1%,7.9%和7.5%,有效提高了破片目标检测准确性。
