BACKGROUND Sessile serrated adenomas(SSAs)are important premalignant lesions that are difficult to detect during colonoscopy due to poor definition,concealment by mucous caps,and flat appearance.High definition(HD)col...BACKGROUND Sessile serrated adenomas(SSAs)are important premalignant lesions that are difficult to detect during colonoscopy due to poor definition,concealment by mucous caps,and flat appearance.High definition(HD)colonoscopy may uniquely aid in the detection of these inconspicuous lesions compared to standard definition(SD)colonoscopes.In the absence of existing clinical guidelines to obligate the use of HD colonoscopy for colorectal cancer screening in average-risk patients,demonstrating the benefit of HD colonoscopy on SSA detection rate(SSADR)may help strengthen the evidence to recommend its use in all settings.AIM To evaluate the benefit of HD colonoscopy compared to SD colonoscopy on SSADR in average-risk patients undergoing screening colonoscopy.METHODS Data from screening colonoscopies for patients aged 50-76 years two years before and two years after the transition from SD colonoscopy to HD colonoscopy at our large,academic teaching center were collected.Patients with symptoms of colorectal disease,positive occult blood test,history of colon polyps,cancer,polyposis syndrome,inflammatory bowel disease or family history of colon cancer or polyps were excluded.Patients whose endoscopists did not perform colonoscopies both before and after scope definition change were also excluded.Differences in individual endoscopist SSADR,average SSADR,and overall SSADR with SD colonoscopy vs HD colonoscopy were also evaluated for significance.RESULTS A total of 3657 colonoscopies met eligibility criteria with 2012 colonoscopies from the SD colonoscopy period and 1645 colonoscopies from the HD colonoscopy period from a pool of 11 endoscopists.Statistically significant improvements of 2.30%in mean SSADR and 2.53%in overall SSADR were noted with HD colonoscopy(P=0.00028 and P=0.00849,respectively).On the individual level,three endoscopists experienced statistically significant benefit with HD colonoscopy(+5.74%,P=0.0056;+4.50%,P=0.0278;+4.84%,P=0.03486).CONCLUSION Our study suggests that HD colonoscopy statistically significantly improves sessile serrated adenoma detection rate in the screening of average risk patients during screening colonoscopy.By improving the detection and removal of these lesions,adoption of HD colonoscopy may reduce the significant premalignant burden of sessile serrated adenomas.展开更多
由于4K超高清(Ultra High Definition,UHD)和高动态范围(High Dynamic Range,HDR)技术的快速发展及其在广播电视制播中的广泛应用,传统广播电视台急需进行技术升级和系统优化。在这一背景下,4K超高清融媒体转播车视频系统的设计与优化...由于4K超高清(Ultra High Definition,UHD)和高动态范围(High Dynamic Range,HDR)技术的快速发展及其在广播电视制播中的广泛应用,传统广播电视台急需进行技术升级和系统优化。在这一背景下,4K超高清融媒体转播车视频系统的设计与优化尤为关键。视频系统不仅需要处理更高分辨率的视频信号,而且必须兼顾HDR内容的传输与处理,还要保持与现有制播流程的兼容性。基于此,系统地对4K超高清融媒体转播车视频系统进行设计优化,包括对摄像机、切换台以及数据交换系统的优化设计,旨在提升视频系统的整体性能,确保高质量的直播信号传输和处理,同时增强系统的灵活性和未来兼容性,为观众提供更加出色的视听体验。展开更多
随着技术不断进步和用户对高清、超高清内容需求的增加,4K超高清融媒体播出系统日渐成为广播电视领域研究的热点。本文对基于串行数字接口(SDI,Serial Digital Interface)的4K超高清融媒体播出系统的设计与实现进行了详细介绍,包括相关...随着技术不断进步和用户对高清、超高清内容需求的增加,4K超高清融媒体播出系统日渐成为广播电视领域研究的热点。本文对基于串行数字接口(SDI,Serial Digital Interface)的4K超高清融媒体播出系统的设计与实现进行了详细介绍,包括相关概述、系统设计和具体应用等。展开更多
文摘BACKGROUND Sessile serrated adenomas(SSAs)are important premalignant lesions that are difficult to detect during colonoscopy due to poor definition,concealment by mucous caps,and flat appearance.High definition(HD)colonoscopy may uniquely aid in the detection of these inconspicuous lesions compared to standard definition(SD)colonoscopes.In the absence of existing clinical guidelines to obligate the use of HD colonoscopy for colorectal cancer screening in average-risk patients,demonstrating the benefit of HD colonoscopy on SSA detection rate(SSADR)may help strengthen the evidence to recommend its use in all settings.AIM To evaluate the benefit of HD colonoscopy compared to SD colonoscopy on SSADR in average-risk patients undergoing screening colonoscopy.METHODS Data from screening colonoscopies for patients aged 50-76 years two years before and two years after the transition from SD colonoscopy to HD colonoscopy at our large,academic teaching center were collected.Patients with symptoms of colorectal disease,positive occult blood test,history of colon polyps,cancer,polyposis syndrome,inflammatory bowel disease or family history of colon cancer or polyps were excluded.Patients whose endoscopists did not perform colonoscopies both before and after scope definition change were also excluded.Differences in individual endoscopist SSADR,average SSADR,and overall SSADR with SD colonoscopy vs HD colonoscopy were also evaluated for significance.RESULTS A total of 3657 colonoscopies met eligibility criteria with 2012 colonoscopies from the SD colonoscopy period and 1645 colonoscopies from the HD colonoscopy period from a pool of 11 endoscopists.Statistically significant improvements of 2.30%in mean SSADR and 2.53%in overall SSADR were noted with HD colonoscopy(P=0.00028 and P=0.00849,respectively).On the individual level,three endoscopists experienced statistically significant benefit with HD colonoscopy(+5.74%,P=0.0056;+4.50%,P=0.0278;+4.84%,P=0.03486).CONCLUSION Our study suggests that HD colonoscopy statistically significantly improves sessile serrated adenoma detection rate in the screening of average risk patients during screening colonoscopy.By improving the detection and removal of these lesions,adoption of HD colonoscopy may reduce the significant premalignant burden of sessile serrated adenomas.
文摘由于4K超高清(Ultra High Definition,UHD)和高动态范围(High Dynamic Range,HDR)技术的快速发展及其在广播电视制播中的广泛应用,传统广播电视台急需进行技术升级和系统优化。在这一背景下,4K超高清融媒体转播车视频系统的设计与优化尤为关键。视频系统不仅需要处理更高分辨率的视频信号,而且必须兼顾HDR内容的传输与处理,还要保持与现有制播流程的兼容性。基于此,系统地对4K超高清融媒体转播车视频系统进行设计优化,包括对摄像机、切换台以及数据交换系统的优化设计,旨在提升视频系统的整体性能,确保高质量的直播信号传输和处理,同时增强系统的灵活性和未来兼容性,为观众提供更加出色的视听体验。
