BACKGROUND The effect of low ligation(LL)vs high ligation(HL)of the inferior mesenteric artery(IMA)on functional outcomes during sigmoid colon and rectal cancer surgery,including urinary,sexual,and bowel function,is s...BACKGROUND The effect of low ligation(LL)vs high ligation(HL)of the inferior mesenteric artery(IMA)on functional outcomes during sigmoid colon and rectal cancer surgery,including urinary,sexual,and bowel function,is still controversial.AIM To assess the effect of LL of the IMA on genitourinary function and defecation after colorectal cancer(CRC)surgery.METHODS EMBASE,PubMed,Web of Science,and the Cochrane Library were systematically searched to retrieve studies describing sigmoid colon and rectal cancer surgery in order to compare outcomes following LL and HL.A total of 14 articles,including 4750 patients,were analyzed using Review Manager 5.3 software.Dichotomous results are expressed as odds ratios(ORs)with 95%confidence intervals(CIs)and continuous outcomes are expressed as weighted mean differences(WMDs)with 95%CIs.RESULTS LL resulted in a significantly lower incidence of nocturnal bowel movement(OR=0.73,95%CI:0.55 to 0.97,P=0.03)and anastomotic stenosis(OR=0.31,95%CI:0.16 to 0.62,P=0.0009)compared with HL.The risk of postoperative urinary dysfunction,however,did not differ significantly between the two techniques.The meta-analysis also showed no significant differences between LL and HL in terms of anastomotic leakage,postoperative complications,total lymph nodes harvested,blood loss,operation time,tumor recurrence,mortality,5-year overall survival rate,or 5-year disease-free survival rate.CONCLUSION Since LL may result in better bowel function and a reduced rate of anastomotic stenosis following CRC surgeries,we suggest that LL be preferred over HL.展开更多
目的探讨右美托咪定联合动画片干预对防治全麻腹腔镜疝囊高位结扎术患儿术后行为改变的临床意义。方法选取2020年4月—2022年12月择期行全麻腹腔镜疝囊高位结扎术的患儿270例为研究对象,根据就诊序号采用电脑随机数字表法分为A组(予以...目的探讨右美托咪定联合动画片干预对防治全麻腹腔镜疝囊高位结扎术患儿术后行为改变的临床意义。方法选取2020年4月—2022年12月择期行全麻腹腔镜疝囊高位结扎术的患儿270例为研究对象,根据就诊序号采用电脑随机数字表法分为A组(予以右美托咪定干预)、B组(予以动画片干预)、C组(予以右美托咪定联合动画片干预),每组90例。比较3组不同时间点平均动脉压(MAP)、心率(HR)、呼气末二氧化碳分压(P ET CO_(2))、血氧饱和度(SpO_(2))、呼吸频率(RR)、改良耶鲁围术期焦虑量表(mYPAS)评分以及诱导期合作度量表(ICC)评分、苏醒期躁动评分量表(PAED)评分、躁动发生率、苏醒情况、术后行为改变情况。结果在术前麻醉准备期间(T 2)、入手术室(T3)、术后苏醒即刻(T4),C组HR、MAP低于A组、B组(P<0.05)。3组P_(ET)CO_(2)、SpO_(2)、RR在组间、时间及组间·时间交互作用比较差异均无统计学意义(P>0.05)。T2、T3时,C组mYPAS评分低于A组、B组(P<0.05)。C组ICC、PAED评分及苏醒期躁动率低于A组、B组(P<0.05)。术后1、7 d,C组行为改变发生率低于A组、B组(P<0.05)。3组拔管时间、意识恢复时间、麻醉恢复室停留时间及不良事件总发生率比较差异无统计学意义(P>0.05)。结论右美托咪定联合动画片干预可降低行全麻腹腔镜疝囊高位结扎术患儿术前焦虑,提升患儿麻醉诱导合作程度,降低苏醒期躁动及术后行为改变发生率,且对患儿血流动力学影响较小,安全性高。展开更多
文摘BACKGROUND The effect of low ligation(LL)vs high ligation(HL)of the inferior mesenteric artery(IMA)on functional outcomes during sigmoid colon and rectal cancer surgery,including urinary,sexual,and bowel function,is still controversial.AIM To assess the effect of LL of the IMA on genitourinary function and defecation after colorectal cancer(CRC)surgery.METHODS EMBASE,PubMed,Web of Science,and the Cochrane Library were systematically searched to retrieve studies describing sigmoid colon and rectal cancer surgery in order to compare outcomes following LL and HL.A total of 14 articles,including 4750 patients,were analyzed using Review Manager 5.3 software.Dichotomous results are expressed as odds ratios(ORs)with 95%confidence intervals(CIs)and continuous outcomes are expressed as weighted mean differences(WMDs)with 95%CIs.RESULTS LL resulted in a significantly lower incidence of nocturnal bowel movement(OR=0.73,95%CI:0.55 to 0.97,P=0.03)and anastomotic stenosis(OR=0.31,95%CI:0.16 to 0.62,P=0.0009)compared with HL.The risk of postoperative urinary dysfunction,however,did not differ significantly between the two techniques.The meta-analysis also showed no significant differences between LL and HL in terms of anastomotic leakage,postoperative complications,total lymph nodes harvested,blood loss,operation time,tumor recurrence,mortality,5-year overall survival rate,or 5-year disease-free survival rate.CONCLUSION Since LL may result in better bowel function and a reduced rate of anastomotic stenosis following CRC surgeries,we suggest that LL be preferred over HL.
文摘目的探讨右美托咪定联合动画片干预对防治全麻腹腔镜疝囊高位结扎术患儿术后行为改变的临床意义。方法选取2020年4月—2022年12月择期行全麻腹腔镜疝囊高位结扎术的患儿270例为研究对象,根据就诊序号采用电脑随机数字表法分为A组(予以右美托咪定干预)、B组(予以动画片干预)、C组(予以右美托咪定联合动画片干预),每组90例。比较3组不同时间点平均动脉压(MAP)、心率(HR)、呼气末二氧化碳分压(P ET CO_(2))、血氧饱和度(SpO_(2))、呼吸频率(RR)、改良耶鲁围术期焦虑量表(mYPAS)评分以及诱导期合作度量表(ICC)评分、苏醒期躁动评分量表(PAED)评分、躁动发生率、苏醒情况、术后行为改变情况。结果在术前麻醉准备期间(T 2)、入手术室(T3)、术后苏醒即刻(T4),C组HR、MAP低于A组、B组(P<0.05)。3组P_(ET)CO_(2)、SpO_(2)、RR在组间、时间及组间·时间交互作用比较差异均无统计学意义(P>0.05)。T2、T3时,C组mYPAS评分低于A组、B组(P<0.05)。C组ICC、PAED评分及苏醒期躁动率低于A组、B组(P<0.05)。术后1、7 d,C组行为改变发生率低于A组、B组(P<0.05)。3组拔管时间、意识恢复时间、麻醉恢复室停留时间及不良事件总发生率比较差异无统计学意义(P>0.05)。结论右美托咪定联合动画片干预可降低行全麻腹腔镜疝囊高位结扎术患儿术前焦虑,提升患儿麻醉诱导合作程度,降低苏醒期躁动及术后行为改变发生率,且对患儿血流动力学影响较小,安全性高。
