AIM： Autologous blood donation （ABD） is mainly used to reduce the use of banked blood. In fact, ABD can be regarded as acute blood loss. Would ABD 2-3 d before operation affect the CVP level and subsequently result...AIM： Autologous blood donation （ABD） is mainly used to reduce the use of banked blood. In fact, ABD can be regarded as acute blood loss. Would ABD 2-3 d before operation affect the CVP level and subsequently result in less blood loss during liver resection was to be determined.METHODS： Eighty-four patients undergoing living donor left hepatectomy were retrospectively divided as group Ⅰ （GⅠ） and group Ⅱ （GⅡ） according to have donated 250-300 mL blood 2-3 d before living donor hepatectomy or not. The changes of the intraoperative CVP, surgical blood loss,blood products used and the changes of perioperative hemoglobin （Hb） between groups were analyzed and compared by using Mann-Whitney Utest.RESULTS： The results show that the intraoperative CVP changes between GⅠ （n = 35） and GⅡ （n = 49） up to graft procurement were the same, subsequently the blood loss,but ABD resulted in significantly lower perioperative Hb levels in GI.CONCLUSION： Since none of the patients required any blood products perioperatively, all the predonated bloods were discarded after the patients were discharged from the hospital. It indicates that ABD in current series had no any beneficial effects, in term of cost, lowering the CVP, blood loss and reduce the use of banked blood products, but resulted in significant lower Hb in perioperative period.展开更多
目的分析不同自体血回输模式对新生儿及凶险性前置胎盘剖宫产孕妇凝血功能的影响。方法将90例凶险性前置胎盘孕妇按照输血模式的不同分为回收组和稀释组,每组45例。比较2组孕妇治疗前后血液成分[血小板计数(PLT)、红细胞比容(Hct)、血...目的分析不同自体血回输模式对新生儿及凶险性前置胎盘剖宫产孕妇凝血功能的影响。方法将90例凶险性前置胎盘孕妇按照输血模式的不同分为回收组和稀释组,每组45例。比较2组孕妇治疗前后血液成分[血小板计数(PLT)、红细胞比容(Hct)、血红蛋白(Hb)]、凝血功能指标[凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)]、血流动力学参数(心率、平均动脉压、血氧饱和度)、新生儿1 min和5 min Apgar评分及不良反应发生情况。结果回收组新生儿1 min、5 min Apgar评分分别为(9.23±0.53)、(9.87±0.61)分,稀释组分别为(9.31±0.57)、(9.89±0.60)分,差异均无统计学意义(t=0.379、0.673,P=0.681、0.482)。回收组不良反应发生率为4.44%,低于稀释组的22.22%,差异有统计学意义(P<0.05)。结论自体血回收与稀释回输模式对孕妇的血液成分、凝血功能、血流动力学及新生儿生理活动的影响均较小,但自体血回收输血模式更为灵活,不良反应更少。展开更多
目的探讨回收式自体输血联合双侧髂内动脉球囊预置术对出血高危患者在剖宫产术中的应用效果。方法前瞻性选取本院2021年1月—2023年5月的162名进行剖宫产的出血高危患者,根据输血方式适应证不同分为A、B、C 3组,每组各54例。A组采用异...目的探讨回收式自体输血联合双侧髂内动脉球囊预置术对出血高危患者在剖宫产术中的应用效果。方法前瞻性选取本院2021年1月—2023年5月的162名进行剖宫产的出血高危患者,根据输血方式适应证不同分为A、B、C 3组,每组各54例。A组采用异体血输入,B组采用自体血输入,C组采用自体输血联合双侧髂内动脉球囊预置术。结果术中出血量(1600 mL vs 1500 mL vs 800 mL)、术后住院时间(7 d vs 7 d vs 6 d)和手术时间(107 min vs 104.50 min vs 77 min)C组均低于A、B 2组(P<0.05),A、B 2组比较无差异(P>0.05);C组输入自体血量低于B组(525.5 mL vs 261 mL,P<0.05)。C组异体红细胞的输入占比低于A组(22.22%vs 100.00%,P<0.0167);C组血浆的输入占比低于A、B 2组(18.50%vs 66.70%/18.50%vs 44.40%,P<0.0167);C组凝血功能障碍发生率低于A组(7.41%vs 25.93%,P<0.0167);C组子宫切除发生率低于A组(1.85%vs 16.67%,P<0.0167),A、B 2组比较无差异(16.67%vs 11.11%,P>0.0167)。结论在出血高危患者剖宫产术中采用回收式自体输血联合双侧髂内动脉球囊预置术效果理想,能明显减少术中失血量、术中自体血回输量、异体红细胞和血浆成分的输入量,同时减少手术时间和术后住院时间。此外,还改善凝血功能和子宫切除情况,有利于保障产妇的生命安全和促进早期康复,且一定程度保留患者生育能力,值得临床进一步推广。展开更多
文摘AIM： Autologous blood donation （ABD） is mainly used to reduce the use of banked blood. In fact, ABD can be regarded as acute blood loss. Would ABD 2-3 d before operation affect the CVP level and subsequently result in less blood loss during liver resection was to be determined.METHODS： Eighty-four patients undergoing living donor left hepatectomy were retrospectively divided as group Ⅰ （GⅠ） and group Ⅱ （GⅡ） according to have donated 250-300 mL blood 2-3 d before living donor hepatectomy or not. The changes of the intraoperative CVP, surgical blood loss,blood products used and the changes of perioperative hemoglobin （Hb） between groups were analyzed and compared by using Mann-Whitney Utest.RESULTS： The results show that the intraoperative CVP changes between GⅠ （n = 35） and GⅡ （n = 49） up to graft procurement were the same, subsequently the blood loss,but ABD resulted in significantly lower perioperative Hb levels in GI.CONCLUSION： Since none of the patients required any blood products perioperatively, all the predonated bloods were discarded after the patients were discharged from the hospital. It indicates that ABD in current series had no any beneficial effects, in term of cost, lowering the CVP, blood loss and reduce the use of banked blood products, but resulted in significant lower Hb in perioperative period.
文摘目的分析不同自体血回输模式对新生儿及凶险性前置胎盘剖宫产孕妇凝血功能的影响。方法将90例凶险性前置胎盘孕妇按照输血模式的不同分为回收组和稀释组,每组45例。比较2组孕妇治疗前后血液成分[血小板计数(PLT)、红细胞比容(Hct)、血红蛋白(Hb)]、凝血功能指标[凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)]、血流动力学参数(心率、平均动脉压、血氧饱和度)、新生儿1 min和5 min Apgar评分及不良反应发生情况。结果回收组新生儿1 min、5 min Apgar评分分别为(9.23±0.53)、(9.87±0.61)分,稀释组分别为(9.31±0.57)、(9.89±0.60)分,差异均无统计学意义(t=0.379、0.673,P=0.681、0.482)。回收组不良反应发生率为4.44%,低于稀释组的22.22%,差异有统计学意义(P<0.05)。结论自体血回收与稀释回输模式对孕妇的血液成分、凝血功能、血流动力学及新生儿生理活动的影响均较小,但自体血回收输血模式更为灵活,不良反应更少。
文摘目的探讨回收式自体输血联合双侧髂内动脉球囊预置术对出血高危患者在剖宫产术中的应用效果。方法前瞻性选取本院2021年1月—2023年5月的162名进行剖宫产的出血高危患者,根据输血方式适应证不同分为A、B、C 3组,每组各54例。A组采用异体血输入,B组采用自体血输入,C组采用自体输血联合双侧髂内动脉球囊预置术。结果术中出血量(1600 mL vs 1500 mL vs 800 mL)、术后住院时间(7 d vs 7 d vs 6 d)和手术时间(107 min vs 104.50 min vs 77 min)C组均低于A、B 2组(P<0.05),A、B 2组比较无差异(P>0.05);C组输入自体血量低于B组(525.5 mL vs 261 mL,P<0.05)。C组异体红细胞的输入占比低于A组(22.22%vs 100.00%,P<0.0167);C组血浆的输入占比低于A、B 2组(18.50%vs 66.70%/18.50%vs 44.40%,P<0.0167);C组凝血功能障碍发生率低于A组(7.41%vs 25.93%,P<0.0167);C组子宫切除发生率低于A组(1.85%vs 16.67%,P<0.0167),A、B 2组比较无差异(16.67%vs 11.11%,P>0.0167)。结论在出血高危患者剖宫产术中采用回收式自体输血联合双侧髂内动脉球囊预置术效果理想,能明显减少术中失血量、术中自体血回输量、异体红细胞和血浆成分的输入量,同时减少手术时间和术后住院时间。此外,还改善凝血功能和子宫切除情况,有利于保障产妇的生命安全和促进早期康复,且一定程度保留患者生育能力,值得临床进一步推广。
