Effect of High Suspension and Low Incision Surgery Based on Traditional Ligation of Chinese Medicine in Treatment of Mixed Haemorrhoids:A Multi-centre,Randomized,Single-Blind,Non-inferiority Clinical Trial

Objective:To observe the clinical effect of high suspension and low incision(HSLI)surgery on mixed haemorrhoids,compared with Milligan-Morgan haemorrhoidectomy.Methods:A multi-centre,randomized,singleblind,non-inferiority clinical trial was performed.Participants with mixed haemorrhoids from Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing Rectum Hospital,Air Force Medical Center of People's Liberation Army of China,and Puyang Hospital of Traditional Chinese Medicine were enrolled from September 2016 to March 2018.By using a blocked randomization scheme,participants were assigned to two groups.The experimental group was treated with HSLI,while the control group was treated with Milligan-Morgan haemorrhoidectomy.The primary outcome was the clinical effect evaluated at 12 weeks after operation.The secondary outcomes included the number of haemorrhoids treated during the operation,pain scores,use of analgesics,postoperative oedema,wound healing,incidence of anal stenosis,anorectal manometry after operation,as well as surgical duration,length of stay and total hospitalization expenses.A safety evaluation was also conducted.Results:In total,246 eligible participants were enrolled,with 123 cases in each group.There was no significant difference in the clinical effect between the two groups(100.00% vs.99.19%,P>0.05).Compared with the control group,the number of external haemorrhoids treated during the operation and the pain scores after operation were significantly reduced in the experimental group(P<0.05 or P<0.01);the patient number with wound healing at 2 weeks after operation and the functional length of anal canal at 12 weeks after operation were significantly increased in the experimental group(P<0.05).There was no significant difference in the incidence of anal stenosis,the numbers of patients using analgesics and patients with postoperative oedema between the two groups after operation(P>0.05).The surgical duration and length of stay in the experimental group were significantly longer than those in the control group,and the total hospitalization expense was significantly higher than that in the control group(all P<0.05).No adverse events were reported in either group during the whole trial or follow-up period.Conclusion:HSLI had the advantages of preserving the skin of anal canal completely,alleviating postsurgical pain and promoting rapid recovery after operation.(Registration No.Chi CTR1900022883).

Comparison of correcting myopia and astigmatism with SMILE or FS-LASIK and postoperative higher-order aberrations

AIM:To compare the effect of myopia and astigmatism correction and postoperative change in higher-order aberration as results of receiving small-incision lenticule extraction(SMILE)and femtosecond laser-assisted in situ keratomileusis(FS-LASIK).METHODS:A prospective and non-randomized controlled study was conducted.The subjects are divided into two groups according to different operations received:229 eyes of 116 patients in the SMILE group and 168 eyes of 86 patients in the FS-LASIK group.All subjects were followed up for 3 mo by monitoring their uncorrected visual acuity(UCVA),best-corrected visual acuity(BCVA),spherical equivalent,higher-order aberrations,and the preoperative and postoperative complications.RESULTS:At 1 wk,1,and 3 mo post-surgery,224 eyes(97.8%),227 eyes(99.1%)and 229 eyes(100%)had UCVA≥20/20 in the SMILE group,while 165 eyes(98.2%),167 eyes(99.4%)and 167 eyes(99.4%)had UCVA≥20/20 in the FS-LASIK group,respectively(χ^(2)=0.146,2.135,and 1.124;all P>0.05).BCVA reduction was not observed in both groups at 1 and 3 mo of post-surgery(χ^(2)=0.734 and 1.898,P>0.05).There was no statistically significant difference in the spherical equivalent between the two groups at 1 and 3 mo post-surgery,though the percentage of the spherical equivalent within±0.50 D at 3 mo postsurgery was 98%in the SMILE group,which was higherthan that of the FS-LASIK group(92%,χ^(2)=1.872,P>0.05).The root mean square(RMS)values of total high-order aberration,coma,and spherical aberration of the two groups increased significantly in the early postoperative period and decreased after 3 mo,but the values were still higher than the preoperative levels(P<0.05);there was no significant difference between the two groups in the RMS values of total higher-order aberrations and specific higherorder aberrations(P>0.05).The incidence of complications in the SMILE group was lower than that in the FS-LASIK group(χ^(2)=14.52,P<0.05).CONCLUSION:SMILE and FS-LASIK can effectively treat myopia,significantly improve visual acuity,and increase the total high-order aberration,spherical aberration,and coma.The incidence of complications after SMILE is relatively low.

Five-year results of refractive outcomes and visionrelated quality of life after SMILE for the correction of high myopia

AIM:To evaluate the long-term visual,refractive outcomes and vision-related quality of life after small incision lenticule extraction(SMILE)for the correction of high myopia.METHODS:Thirty patients(60 eyes)with high myopia who underwent SMILE more than 5y were selected as the SMILE group.Another 30 high myopia patients(60 eyes)who had worn corrective spectacles for more than 5y were selected as the control group.In SMILE group,the postoperative follow-up time were 3,6 mo,1 and 5y.Uncorrected distance visual acuity(UDVA),corrected distance visual acuity(CDVA),spherical equivalent(SE),and ocular axial length(AL)were analyzed.The Chinese version of the National Eye Institute Visual Function Questionnaire-25(CHI-NEI-VFQ-25)was used to evaluate the vision-related quality of life in the SMILE group and the control group.RESULTS:In SMILE group,the mean preoperative SE was-7.29±0.87 D(range-6.00 to-9.125 D).At 5-year follow up,the efficacy index and safety index of SMILE were 1.09±0.18 and 1.19±0.12,respectively.Five years postoperatively,44 eyes(73%)obtained a visual acuity of 20/20 or better.There were no eyes with CDVA loss of one or more Snellen lines.Forty-nine eyes(82%)and 57 eyes(95%)were within±0.50 and±1.00 D of attempted correction at 5-year follow-up,respectively.Forty-eight eyes(80%)had astigmatism<0.50 D at 5-year followup.The postoperative mean SE values at 3,6 mo,1,and 5y were 0.11±0.44,0.07±0.45,-0.02±0.41,and-0.15±0.46 D,respectively.No significant change was observed in the ocular AL from before operation to 5y postoperatively(26.08±0.96 mm vs 26.01±0.94 mm,P=0.068).Compared to the control group,the SMILE group showed a significantly higher total score on the CHI-NEI-VFQ-25(90.14 vs 81.43,P<0.001).CONCLUSION:In the present study,in a long-term follow-up we demonstrate that correcting high myopia with SMILE is safe,effective,and predictable.Vision-related quality of life after SMILE is better in the SMILE group than in the control group who wore corrective spectacles.

Postoperative changes in corneal epithelial and stromal thickness profiles after SMILE in high myopic eyes

Background:To observe changes in the epithelial and stromal thickness after small incision refractive lenticule extraction(SMILE)and investigate their relationship with the different refractive error.Methods:One hundred and eighty eyes of 90 patients with a manifest refraction spherical equivalent(MRSE)of-6.36±1.53 diopters(D)were included.The eyes were assigned to the moderate myopic group(MRSE-3.00 to-6.00 D),high myopic group(MRSE-6.00 to-8.00 D)and super-high myopic group(MRSE above-8.00 D).The spectral-domain optical coherence tomography(SD-OCT)measured corneal and epithelial thickness in 17 zones preoperatively and 1,3,and 6 months postoperatively.Stromal thickness was calculated by subtracting the epithelial thickness from the total corneal thickness.The observed changes were correlated with the degree of myopia corrected.Results:MRSE showed significant differences between 3 and 6 months in the super-high myopic group(P=0.024).At 6 months,a statistically significant epithelial thickness increase was observed in the central zone(7.18%for moderate,10.23%for high,and 13.76%for super-high myopia,P<0.05 for all groups).The peripheral thickness decreased between 3 and 6 months in the high myopia and super-high myopia groups(P<0.05,respectively).A positive correlation between MRSE corrected and the postoperative epithelial thickening was observed in the central(r2=0.551,P<0.05).Compared to 1 month values,the central stromal thickness showed a decrease(3.2±4.5μm)at 3 months and an increase(4.4±4.9μm)at 6 months.The stroma thickened in moderate and high myopic groups but the thickness reduction were in super-high myopia group at 6 months paracentrally and peripherally.Conclusions:Significant thickness changes in the epithelium and stroma were detected during the 6 months after SMILE.Preliminary results suggest that epithelial and stromal thickness profile changes after SMILE may have an impact on the refractive outcome in the long-term postoperative period,especially in super-higher degrees of myopia.

不同手术方法对高位复杂性肛瘘患者肛门功能的影响

目的探讨传统切开挂线术和切开挂线选择性缝合术治疗高位复杂性肛瘘患者的效果。方法84例高位复杂性肛瘘患者按手术方式的不同分为两组,对照组采取传统切开挂线术治疗,研究组采取切开挂线选择性缝合术治疗,比较两组的治疗效果、疼痛程度、肛门功能、术后并发症。结果研究组的治疗总有效率明显高于对照组,术后7d的VAS评分、术后6个月的Wexner评分、术后并发症发生率均明显低于对照组(P<0.05)。结论与传统切开挂线术相比,切开挂线选择性缝合术治疗高位复杂性肛瘘患者的效果更好,可降低患者疼痛程度,改善肛门功能,降低术后并发症发生率。

SMILE术后患者早期角膜生物力学变化与角膜体积变化、角膜高阶像差变化之间的关系

目的探讨飞秒激光小切口角膜基质透镜取出术(SMILE)术后患者早期角膜生物力学的变化,分析角膜生物力学变化与角膜体积变化、角膜高阶像差变化之间的关系。方法选取2021年1月至8月在佛山市第二人民医院视光学中心拟行SMILE的近视及近视散光患者72例(72眼)作为研究对象,取患者的右眼作为观测眼。术前和术后3个月分别应用新一代Corvis ST测量患者角膜生物力学新型参数[非接触生物力学校正眼压(bIOP)、2 mm处变形幅度的比值(DA ratio)、综合半径(IR)、最薄点厚度/厚度变化率(ARTh;用来评估角膜的形态和质量)、第一次压平时角膜硬度参数(SP-A1)、Corvis生物力学指数(CBI)和应力和应变参数(SSI)];应用Pentacam测量患者角膜生物力学参数,包括:角膜体积(CV_(3 mm)、CV_(5 mm)、CV_(7 mm)和CV_(10 mm));全角膜、角膜前表面、角膜后表面总均方根[RMS(Cornea、CF、CB)];全角膜、角膜前表面、角膜后表面高阶像差均方根[RMS HOA(Cornea、CF、CB)]。采用配对t检验或Wilcoxon符号秩检验分析各项参数的变化;采用偏最小二乘回归分析和Spearman相关性分析研究SMILE术后角膜生物力学新型参数变化量与角膜体积变化量、角膜高阶像差参数变化量之间的相关性。结果术后3个月,患者角膜bIOP、ARTh、SP-A1和SSI较术前明显下降;DA^(ratio)、IR和CBI较术前明显升高,差异均有统计学意义(均为P<0.05)。术后3个月,患者角膜CV_(3 mm)、CV_(5 mm)、CV_(7 mm)和CV_(10 mm)均较术前显著降低,差异均有统计学意义(均为P<0.05)。角膜体积变化量从小到大依次为CV_(3 mm)、CV_(5 mm)、CV_(7 mm)、CV_(10 mm),越往周边减少量增加。术后3个月,患者RMS(Cornea、CF、CB)、RMS HOA(Cornea、CF、CB)均较术前显著增加,差异均有统计学意义(均为P<0.05);相对于角膜前表面高阶像差的变化,角膜后表面高阶像差的变化相对稳定。相关分析结果显示,△ARTh与△CV_(3 mm)、△CV_(5 mm)均呈正相关,与△CV_(10 mm)呈负相关(均为P<0.05);△bIOP与△CV_(3 mm)、△CV_(5 mm)、△RMS HOA(CF)、△RMS HOA(Cornea)均呈负相关,与△CV_(10 mm)呈正相关(均为P<0.05);△IR与△CV_(10 mm)呈负相关(P<0.05);△SP-A1与△CV_(10 mm)呈正相关(P<0.05);△CBI与△CV_(3 mm)、△CV_(5 mm)均呈负相关,与△CV_(10 mm)、△RMS(CF)均呈正相关(均为P<0.05)。结论SMILE术后患者早期角膜生物力学发生了一些变化,这些角膜生物力学变化与不同区域角膜体积变化、角膜高阶像差参数变化存在一定的相关性。

不同程度近视患者行SMILE术后的有效光学区及角膜高阶像差比较

目的:比较低、中、高度近视患者行飞秒激光小切口基质透镜取出术(SMILE)后的有效光学区和角膜高阶像差。方法:收集2019-02/2021-02在我院行SMILE手术的患者134例,均取右眼入组,按等效球镜度(SE)分为低度近视组SE>-3.00 D,中度近视组-6.00 D<SE≤-3.00 D,高度近视组SE≤-6.00 D三组,分别于术前和术后1 mo行Pentacam检查,分析各组内手术前后角膜总高阶像差(tHOA)、球差、彗差有无差异,及术后三组间角膜总高阶像差、球差、彗差及有效光学区大小(EOZ)有无差异。结果:SMILE术后1 mo,三组术后有效光学区均小于预设光学区,随着屈光度数增加,有效光学区越小(P<0.05);术后1 mo角膜总高阶像差、球差、彗差均高于术前,除低近视度组球差术前与术后1 mo无差异(P>0.05),其余组别均有差异(P<0.05);角膜总高阶像差、球差和彗差随着屈光度数增加而增加,三组角膜总高阶像差和球差有差异(均P<0.05),高度近视组与中度近视组、低度近视组彗差结果均有差异(P<0.05),中度近视组与低度近视组彗差结果无差异(P>0.05)。结论:随着手术矫正的屈光度数增加,术后有效光学区减少越多,角膜高阶像差增加越明显;SMILE术后1 mo角膜高阶像差较术前增加。

SMILE与ICL植入术治疗伴低度散光的高度近视患者的疗效比较

目的:比较全飞秒激光小切口角膜基质透镜取出术(SMILE)与有晶状体眼后房型人工晶状体(ICL)植入术治疗伴低度散光的高度近视患者的疗效、安全性及视觉质量的临床效果。方法:回顾性研究。纳入2021-01/2022-01我院收治伴低度散光的高度近视患者80例159眼,根据手术方式不同分为SMILE组46例91眼和ICL植入组34例68眼。比较两组患者术前,术后3、6 mo等效球镜、裸眼视力(UCVA)、最佳矫正视力(BCVA)以及角膜高阶像差、光学质量指标(SR)及有效性、安全性指数,统计手术并发症。结果:两组术后6 mo等效球镜、UCVA及BCVA均较术前提高(均P<0.05)。术后6 mo,两组患者UCVA、BCVA、等效球镜、有效性指数、安全性指数比较均无差异(均P>0.05),SMILE组患者总高阶像差、球差、彗差、垂直彗差和水平彗差的均方根值均高于ICL植入组,术后3、6 mo ICL植入组SR高于SMILE组(均P<0.05)。结论:SMILE和ICL植入术治疗伴低度散光的高度近视患者的手术效果良好,术后患者均能获得较好的术后视力和客观视觉质量,相比于SMILE,ICL植入术术后视觉质量更好。

SMILE和超薄瓣FS-LASIK矫正中度近视疗效比较

目的比较飞秒激光小切口角膜基质透镜取出术(SMILE)和超薄瓣飞秒激光辅助准分子激光原位角膜磨镶术(FS‐LASIK)矫正中度近视的临床疗效。方法回顾性病例对照研究。本研究纳入了年龄、性别和角膜厚度匹配合适的中度近视(等效球镜度-3.00~-6.00 D)患者,36例接受SMILE治疗患者的72只眼和36例接受超薄瓣FS‐LASIK治疗患者的72只眼。分别于术前及术后3个月记录所有患者的视力、屈光度及角膜高阶像差等变量,最后进行统计学分析以评估手术疗效。结果在术后随访3个月时,SMILE组和超薄瓣FS‐LASIK组疗效指数和安全指数比较,差异无统计学意义(t=1.179和-0.255,P=0.242和0.800)。SMILE组和超薄瓣FS‐LASIK组术后屈光度呈正视并相对稳定,术后等效球镜度比较差异无统计学意义(t=0.206,P=0.837)。SMILE组和超薄瓣FS‐LASIK组患者的角膜后表面曲率和非球面因子Q值比较,差异无统计学意义(t=-1.852和0.576,P=0.066和0.566)。SMILE组和超薄瓣FS‐LASIK组患者术前的总高阶像差、球差及彗差与术后比较,差异均具有统计学意义(均P<0.05)。在术后3个月时,SMILE组患者的总高阶像差及球差明显低于超薄瓣FS‐LASIK组(均P<0.05)。结论SMILE和超薄瓣FS‐LASIK两种术式矫治中度近视均安全有效,但SMILE组患者的术后总高阶像差及球差增加量低于超薄瓣FS‐LASIK组。

优质护理服务在儿童青少年门诊小切口腋部臭汗症手术中的应用

目的探讨优质护理服务在儿童青少年门诊小切口腋部臭汗症手术中的应用效果。方法选取2021年7月至2023年3月在临沂市费县人民医院门诊手术室行小切口腋部臭汗症手术治疗的86例患儿作为研究对象,按照单双号法将其分为对照组(43例)与观察组(43例)。对照组采用常规护理服务,观察组采用优质护理服务,比较两组护理总满意率、并发症总发生率和护患纠纷发生率。结果观察组护理总满意率高于对照组(P<0.05);观察组并发症总发生率、护患纠纷发生率低于对照组(P<0.05)。结论优质护理服务在儿童青少年门诊小切口腋部臭汗症手术中应用,可以降低并发症及护患纠纷发生率,提高护理满意度。

切开扩创引流合并挂线法治疗高位复杂性肛瘘患者的临床效果

目的针对高位复杂性肛瘘(HAF)患者行切开扩创引流合并挂线法治疗,观察其临床疗效及对患者肛肠功能的影响。方法66例HAF患者,依据随机数字表法分为对照组与观察组,每组33例。对照组患者行单纯切开挂线法治疗,观察组患者在对照组基础上联合切开扩创引流治疗。比较两组术后恢复指标、肛肠动力学指标、疗效及并发症发生情况。结果观察组患者创面愈合时间(21.45±2.36)d、住院时间(16.42±1.45)d均较对照组的(27.16±2.42)、(22.61±1.61)d短,瘢痕面积(3.53±0.22)cm^(2)较对照组的(5.16±0.35)cm^(2)更小(P<0.05)。术后1周,观察组肛管静息压、直肠静息压、肛管最大收缩压与术前比较差异不明显(P>0.05);对照组肛管静息压、直肠静息压、肛管最大收缩压较术前降低明显(P<0.05);观察组术后1周肛管静息压、直肠静息压、肛管最大收缩压高于对照组(P<0.05)。观察组总有效率90.91%较对照组的69.70%更高(P<0.05)。观察组并发症发生率6.06%较对照组的24.24%更低(P<0.05)。结论HAF患者在切开挂线法基础上联合切开扩创引流治疗,有利于缓解疼痛、促进术后恢复,对肠道功能具有一定的保护作用,并发症少,疗效可靠。

腹腔镜阑尾切除术后切口感染发生情况及高危因素分析

目的探讨急性阑尾炎(AA)患者行腹腔镜阑尾切除术(LA)治疗后切口感染发生情况及其影响因素。方法回顾性分析542例AA患者的临床资料,均行LA进行治疗,依据术后是否发生切口感染分为非感染组(n=462)与感染组(n=80)。采用调查问卷调查两组一般资料,并采取单因素分析、多因素Logistic回归分析法,分析LA术后发生切口感染的高危因素。结果542例患者中,共发生切口感染80例,切口感染发生率为14.76%(80/542)。单因素分析显示,感染组年龄>50岁、病程>24 h、病理类型为化脓性或坏疽穿孔性阑尾炎、合并基础疾病、手术时间>1.5 h及有吸烟史占比分别为67.5%(54/80)、66.3%(53/80)、72.5%(58/80)、62.5%(50/80)、68.8%(55/80)、36.3%(29/80),均高于非感染组的44.8%(207/462)、31.0%(143/462)、24.9%(115/462)、27.1%(125/462)、35.1%(162/462)、21.9%(101/462)(P<0.05)。多因素Logistic回归分析显示,年龄>50岁、病程>24 h、病理类型为化脓性或坏疽穿孔性阑尾炎、合并基础疾病、手术时间>1.5 h及有吸烟史均是导致AA患者行LA术后发生切口感染的高危因素(P<0.05)。结论年龄、病程、病理类型、合并基础疾病、手术时间及吸烟史均是导致AA患者术后切口感染发生的影响因素,临床护理过程中应加以重视,并开展相应的干预措施。

RPH联合高悬低切术治疗环状混合痔临床疗效与安全性探讨

目的:探讨RPH联合高悬低切术治疗环状混合痔的临床疗效及安全性。方法:取医院收治的环状混合痔患者120例作为研究对象,按数字表法将其随机分为对照A组(40例)、对照B组(40例)和观察组(40例)。对照A组给予吻合器痔上黏膜环切术(PPH)治疗,对照B组给予外剥内扎术(MMH)联合自动弹力线痔套扎术(RPH)治疗,观察组给予RPH联合高悬低切术治疗。结果:观察组患者临床治疗的总有效率高于对照A组、对照B组(P<0.05)。观察组患者在伤口出血持续时间、创面愈合时间、术后伤口疼痛持续时间、住院时间均短于对照A组、对照B组,术中出血量低于对照组(P<0.05)。观察组患者术后并发症发生率明显低于对照A组、对照B组(P<0.05)。结论:在环状混合痔的患者中,RPH联合高悬低切术可有效缓解疼痛和水肿症状,加速伤口愈合,降低并发症发生率,保护肛门功能。

对比经肛括约肌间切开术和切开挂线法治疗高位肛瘘对患者肛门功能恢复和复发的影响

目的探讨经肛括约肌间切开术和切开挂线法治疗高位肛瘘的临床疗效及其对患者肛门功能恢复和复发的影响。方法91例高位肛瘘患者,根据手术方法的不同分为经肛括约肌间切开组(50例)和切开挂线组(41例)。经肛括约肌间切开组患者采用经肛括约肌间切开术进行治疗,切开挂线组患者采用切开挂线法进行治疗。比较两组患者临床疗效、临床指标(手术时间、愈合时间、术中出血量及住院时间)、视觉模拟评分法(VAS)评分、大便失禁严重度(Wexner)评分、肛门功能及复发情况。结果治疗后经肛括约肌间切开组临床总有效率96.00%高于切开挂线组的78.05%(P<0.05)。经肛括约肌间切开组患者手术时间(58.98±3.71)min、愈合时间(22.24±1.71)d及住院时间(9.38±1.59)d均短于切开挂线组的(75.73±2.95)min、(27.44±1.86)、(14.73±2.05)d,术中出血量(84.96±2.85)ml少于切开挂线组的(96.07±2.71)ml(P<0.05)。术后1个月,两组VAS评分与Wexner评分均较本组术前降低,且经肛括约肌间切开组VAS评分(1.54±0.61)分与Wexner评分(1.22±0.42)分均低于切开挂线组的(2.17±0.70)、(1.93±0.82)分(P<0.05)。术后3个月,两组肛管最大收缩压与肛管最大静息压均较本组术前降低,但经肛括约肌间切开组肛管最大收缩压(16.23±1.62)kPa与肛管最大静息压(8.03±1.01)kPa均大于切开挂线组的(11.17±1.78)、(4.38±0.92)kPa(P<0.05)。结论相较于切开挂线法,经肛括约肌间切开术在高位肛瘘中的临床疗效更加理想,可有效促进患者恢复,同时减轻患者疼痛程度,保护患者肛门功能。

马来酸噻吗洛尔眼液预防高度近视SMILE术后屈光回退的临床研究

目的:观察马来酸噻吗洛尔眼液预防高度近视飞秒激光小切口角膜基质透镜取出术(small incision lenticule extraction,SMILE)术后屈光回退的效果。方法:选取2022年11月至2023年7月在遵义医科大学黔西南附属医院眼科行SMILE的76例(134眼)高度近视患者,将患者随机分成观察组与对照组,两组患者术后均予常规滴眼液点眼治疗,观察组在术后第1天加点马来酸噻吗洛尔眼液,每日2次,连续点眼1个月。两组患者均采集术前裸眼视力(uncorrected visual acuity,UCVA)、眼压、等效球镜度(spherical equivalent,SE)、眼轴、中央角膜厚度(central corneal thickness,CCT)和角膜表面曲率(K1、K2),术后1周及1、3、6个月UCVA、眼压、SE、眼轴、CCT、K1、K2。结果:术后6个月观察组UCVA优于对照组(1.21±0.27 vs.1.10±0.16,P<0.05);对照组术后6个月UCVA较术后1周下降(P<0.05);在术后3、6个月两组患者SE差异均有统计学意义[(-0.16±0.50)D vs.(+0.06±0.38)D,P<0.05;(-0.35±0.52)D vs.(-0.04±0.40)D,P<0.05];两组患者SE在术后6个月与术后1周差异具有统计学意义(P<0.05),对照组术后6个月SE均较术后1周回退;在术后1周、1个月两组患者眼压差异具有统计学意义(P<0.05),观察组患者眼压低于对照组;术后不同时间点两组患者角膜曲率K1、K2、CCT及眼轴均无差异(P>0.05),但两组患者术后1、3、6个月CCT与术后1周差异具有统计学意义(P<0.05)。结论:高度近视患者SMILE术后应用马来酸噻吗洛尔眼液可有效抑制房水生成而降低眼压,使角膜在稳定状态下愈合,阻止角膜表面前移,进而起到预防屈光回退的效果。

单孔腹腔镜疝囊高位结扎术治疗小儿腹股沟疝的效果分析

目的探讨单孔腹腔镜疝囊高位结扎术用于小儿腹股沟疝治疗中的效果及对切口美观度的影响。方法选取2020年9月—2023年7月晋江市医院小儿外科收治的109例小儿腹股沟疝患儿,对其资料行回顾性分析,按照手术方法差异分组,对照组52例采取传统小切口疝囊高位结扎术,观察组57例采取单孔腹腔镜疝囊高位结扎术。比较2组手术效果、切口美观满意度及并发症发生率。结果观察组手术时间、术后肛门排气时间、下床活动时间、住院时间及切口长度短于对照组,观察组术中出血量少于对照组(P<0.05)。观察组术后切口美观满意度为96.49%,明显高于对照组的86.42%(P<0.05)。观察组术后并发症发生率为1.75%,低于对照组的17.31%(P<0.05)。结论单孔腹腔镜疝囊高位结扎术治疗小儿腹股沟疝效果满意,且创伤更小、术后疼痛更轻,术后恢复快,可减轻氧化应激反应及炎症反应,能提高切口美观满意度,也可减少术后并发症发生。

经肛括约肌间切开术治疗高位肌间感染肛瘘的临床效果及安全性

目的:探究高位肌间感染肛瘘患者应用经肛括约肌间切开术(TROPIS)治疗的临床效果。方法:采用随机数字表法将景德镇市中医医院2022年10月—2023年10月收治的80例高位括约肌间感染的肛瘘患者分为两组,每组40例。对照组采用肛瘘切开挂线术,观察组应用TROPIS治疗。对比两组临床疗效、疼痛评分、创面愈合情况、肛门失禁评分、并发症。结果:观察组治疗总有效率为97.50%,高于对照组的80.00%,差异有统计学意义(P<0.05)。与对照组相比,观察组术后第1、3、7天的视觉模拟评分法(VAS)评分均较低,差异均有统计学意义(P<0.05)。与对照组相比,观察组创面愈合时间较早;术后第3天、第7天的Wexner肛门失禁评分均较低,差异均有统计学意义(P<0.05)。与对照组并发症发生率25.00%相比,观察组的2.50%较低,差异有统计学意义(P<0.05)。结论:采用TROPIS治疗高位肌间感染肛瘘患者更有利于提高治疗效果,减轻术后疼痛,降低肛门失禁的风险,减少并发症发生风险。

腹腔镜小儿疝囊高位结扎术与开放式小切口手术治疗小儿腹股沟斜疝的临床疗效比较

目的探讨腹腔镜小儿疝囊高位结扎术与开放式小切口手术治疗小儿腹股沟斜疝的临床疗效。方法选取2020年4月至2021年8月萍乡市妇幼保健院收治的86例小儿腹股沟斜疝患儿作为研究对象,按照手术方式不同分为对照组与观察组,每组43例。对照组采用开放式小切口手术治疗,观察组采用腹腔镜小儿疝囊高位结扎术治疗,比较两组临床疗效、手术情况、术后不同阶段的疼痛程度、并发症发生情况和术后复发情况。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组手术时间、下床活动时间、术后排气时间和住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05);术后24、36h,观察组视觉模拟评分法(visual analogue scale,VAS)均低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率和复发率均低于对照组,差异有统计学意义(P<0.05)。结论腹腔镜小儿疝囊高位结扎术治疗小儿腹股沟斜疝的效果较开放式小切口手术显著,可缩短手术时间,减轻术后疼痛程度,加快康复进程,还可减少并发症发生率和复发率,值得临床推广应用。

TROPIS改良挂线法和传统切开挂线术治疗高位肛瘘的临床效果及安全性比较

目的探讨经肛括约肌间切开(TROPIS)改良挂线法与传统切口挂线术治疗高位肛瘘的临床效果.方法选取我院2021年5月—2023年5月收治的72例高位肛瘘患者为研究对象,按随机数字表法将其分为对照组与观察组,各36例.对照组采用传统切开挂线术治疗,观察组采用TROPIS改良挂线法治疗.比较两组患者的手术情况、术后恢复情况、疼痛评分、肛门功能及并发症发生情况.结果观察组手术时间、住院时间分别为(62.52±6.13)min、(8.52±1.13)d,均短于对照组,术中出血量为(80.41±6.32)mL,少于对照组,组间差异有统计学意义(P<0.05).观察组便血、脓腐脱落及创面愈合时间分别为(5.12±1.02)d、(4.08±0.46)d、(25.63±2.38)d,均短于对照组,组间差异有统计学意义(P<0.05).术后1、3、7 d时,观察组疼痛视觉模拟评分分别为(3.96±0.45)分、(2.81±0.38)分、(1.81±0.24)分,均低于对照组,组间差异有统计学意义(P<0.05).术后3个月,观察组耻骨直肠肌、内括约肌MUP平均时限分别为(6.95±1.05)ms、(7.57±1.12)ms,均长于对照组,肛管静息压、最大收缩压分别为(45.11±4.15)mmHg(1 mmHg=0.133 kPa)、(176.52±11.33)mmHg,均高于对照组,组间差异有统计学意义(P<0.05).观察组并发症发生率低于对照组,差异有统计学意义(P<0.05).结论TROPIS改良挂线法治疗高位肛瘘效果更佳,可减轻手术创伤,降低术后疼痛评分,保护肛门功能,且并发症少.

关节镜下高位关节内与小切口低位关节外结节间沟下LHBT切断固定治疗伴有肱二头肌长头肌腱炎SIS的对照研究

目的:探讨关节镜下高位关节内与小切口低位关节外结节间沟下肱二头肌长头腱(Long Head of the Biceps Tendon,LHBT)切断固定治疗伴有肱二头肌长头肌腱炎肩峰撞击综合征(subacromial impingement syndrome,SIS)的对照研究。方法:选取2019年月12月至2022年12月在我院诊治的伴有肱二头肌长头肌腱炎SIS患者92例,其中45例接受关节镜下高位关节内LHBT切断固定治疗(观察A组),47例接受小切口低位关节外结节间沟下LHBT切断固定治疗(观察B组),比较两组治疗前后的加州大学(UCLA)肩关节评分系统各维度评分及总分、Constant肩关节评分评分、美国肩肘关节医师协会(ASES)评分,以及临床治疗疗效。结果:治疗后,两组UCLA各维度评分、患者满意度及总分较治疗前均升高(P<0.05),但与观察B组比较,观察A组UCLA各维度评分、患者满意度及总分治疗前后的差值明显更低(P<0.05)。治疗后,两组Constant、ASES评分较治疗前均升高(P<0.05),但与观察B组比较,观察A组Constant、ASES评分治疗前后的差值明显更低(P<0.05)。与观察B组95.74%比较,观察A组临床治疗总有效率80.00%明显更低(P<0.05)。结论:与关节镜下高位关节内LHBT切断固定治疗相比较,小切口低位关节外结节间沟下LHBT切断固定治疗伴有肱二头肌长头肌腱炎SIS患者,可更有效促进肩关节功能恢复,提高临床治疗疗效。