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High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration 被引量:4
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作者 Jun-Seob Song Ki-Taek Hong +6 位作者 Chae-Gwan Kong Na-Min Kim Jae-Yub Jung Han-Soo Park Young Ju Kim Ki Bong Chang Seok Jung Kim 《World Journal of Stem Cells》 SCIE CAS 2020年第6期514-526,共13页
BACKGROUND High tibial osteotomy(HTO)is a well-established method for the treatment of medial compartment osteoarthritis of the knee with varus deformity.However,HTO alone cannot adequately repair the arthritic joint,... BACKGROUND High tibial osteotomy(HTO)is a well-established method for the treatment of medial compartment osteoarthritis of the knee with varus deformity.However,HTO alone cannot adequately repair the arthritic joint,necessitating cartilage regeneration therapy.Cartilage regeneration procedures with concomitant HTO are used to improve the clinical outcome in patients with varus deformity.AIM To evaluate cartilage regeneration after implantation of allogenic human umbilical cord blood-derived mesenchymal stem cells(hUCB-MSCs)with concomitant HTO.METHODS Data for patients who underwent implantation of hUCB-MSCs with concomitant HTO were evaluated.The patients included in this study were over 40 years old,had a varus deformity of more than 5°,and a full-thickness International Cartilage Repair Society(ICRS)grade IV articular cartilage lesion of more than 4 cm2 in the medial compartment of the knee.All patients underwent second-look arthroscopy during hardware removal.Cartilage regeneration was evaluated macroscopically using the ICRS grading system in second-look arthroscopy.We also assessed the effects of patient characteristics,such as trochlear lesions,age,and lesion size,using patient medical records.RESULTS A total of 125 patients were included in the study,with an average age of 58.3±6.8 years(range:43-74 years old);95(76%)were female and 30(24%)were male.The average hip-knee-ankle(HKA)angle for measuring varus deformity was 7.6°±2.4°(range:5.0-14.2°).In second-look arthroscopy,the status of medial femoral condyle(MFC)cartilage was as follows:73(58.4%)patients with ICRS grade I,37(29.6%)with ICRS grade II,and 15(12%)with ICRS grade III.No patients were staged with ICRS grade IV.Additionally,the scores[except International Knee Documentation Committee(IKDC)at 1 year]of the ICRS grade I group improved more significantly than those of the ICRS grade II and III groups.CONCLUSION Implantation of hUCB-MSCs with concomitant HTO is an effective treatment for patients with medial compartment osteoarthritis and varus deformity.Regeneration of cartilage improves the clinical outcomes for the patients. 展开更多
关键词 ALLOGENEIC Human umbilical cord blood-derived mesenchymal stem cells Cartilage regeneration high tibial osteotomy Osteoarthritic knees ARTHROSCOPY
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Impact of medial open-wedge high tibial osteotomy for medial compartment osteoarthritis of the knee 被引量:1
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作者 Sunil Sheshrao Nikose Devashree Nikose +3 位作者 Aditya L Kekatpure Shashank Jain Kiran Saoji Sridhar M Reddy 《World Journal of Orthopedics》 2020年第12期606-614,共9页
BACKGROUND Most populations worldwide,who are used to squatting and sitting cross-legged for their activities of daily living,largely comprise the lower socioeconomic strata,thus making them candidates for exclusion f... BACKGROUND Most populations worldwide,who are used to squatting and sitting cross-legged for their activities of daily living,largely comprise the lower socioeconomic strata,thus making them candidates for exclusion for total knee arthroplasty.Proximal/high tibial osteotomy(HTO)is a preferred strategy for clinically symptomatic osteoarthritis(OA)with genu varum due to painful medial compartment OA which is not amenable to conservative measures.AIM To evaluate the outcomes of medial open-wedge HTO along with autologous bone grafting and buttress plate for the treatment of genu varum due to OA of the knee in a rural population of central India.METHODS A total of 65 knees in 56 patients with a mean age of 58.22±5.63 years with genu varum due to intractable painful knee OA were treated with medial open-wedge HTO along with autologous bone grafting and buttress plate osteosynthesis from June 2015 to May 2018.The mean preoperative radiological angle of genu varum was 13.4°.Clinical outcomes were assessed by the range of movement,knee scores,pain scores,and functional scores.Radiographic studies were performed preoperatively and at regular intervals during the follow-up period.RESULTS All patients reported pain relief immediately after the osteotomy and during the long-term analysis covering between one to three years.The genu varum angle was overcorrected to approximately four degrees in all patients.There was a loss of reduction by approximately three degrees in all patients at around six weeks postoperatively.Preoperative knee movements were restored in all patients.No major perioperative complications were noted during surgery and postoperative follow-up and the clinical scores were significantly improved during the final analysis which revealed good pain relief.CONCLUSION Medial open-wedge HTO is a reliable,safe,practical,physiological,and feasible treatment for populations who are used to increased activity in their occupation and lifestyle and is associated with excellent short-term and long-term results for OA in genu varum knees. 展开更多
关键词 high tibial osteotomy Total knee arthroplasty Genu varum OSTEOARTHRITIS OSTEOSYNTHESIS Knee Society Score
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Osteotomy combined with anterior cruciate ligament reconstruction for anterior cruciate ligament injury and biplanar deformity
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作者 Fu-Yuan Deng Jun-Cai Liu Zhong Li 《World Journal of Clinical Cases》 SCIE 2024年第22期4897-4904,共8页
BACKGROUND It has been confirmed that the increased posterior tibial slope over 12 degrees is a risk factor for anterior cruciate ligament injury,and varus deformity can aggravate the progression of medial osteoarthri... BACKGROUND It has been confirmed that the increased posterior tibial slope over 12 degrees is a risk factor for anterior cruciate ligament injury,and varus deformity can aggravate the progression of medial osteoarthritis.AIM To evaluate the efficacy of modified high tibial osteotomy(HTO)and anterior cruciate ligament reconstruction(ACLR)in the treatment of anterior cruciate ligament(ACL)injuries with varus deformities and increased posterior tibial slope(PTS)based on clinical and imaging data.METHODS The patient data in this retrospective study were collected from 2019 to 2021.A total of 6 patients were diagnosed with ACL injury combined with varus deformities and increased PTS.All patients underwent modified open wedge HTO and ACLR.The degree of correction of varus deformity and the PTS was evaluated by radiography and magnetic resonance imaging.RESULTS All 6 patients(6 knee joints)were followed up for an average of 20.8±3.7 months.The average age at surgery was 29.5±3.8 years.At the last follow-up,all patients resumed competitive sports.The International Knee Documentation Committee score increased from 50.3±3.1 to 87.0±2.8,the Lysholm score increased from 43.8±4.9 to 86±3.1,and the Tegner activity level increased from 2.2±0.7 to 7.0±0.6.The average movement distance of the tibia anterior translation was 4.8±1.1 mm,medial proximal tibial angle(MPTA)was 88.9±1.3°at the last follow-up,and the PTS was 8.4±1.4°,both of which were significantly higher than those before surgery(P<0.05).CONCLUSION Modified open wedge HTO combined with ACLR can effectively treat patients with ACL ruptures with an associated increased PTS and varus deformity.The short-term effect is significant,but the long-term effect requires further follow-up. 展开更多
关键词 Anterior cruciate ligament reconstruction Varus deformity high tibial osteotomy Posterior tibial slope Biplanar deformity
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Techniques of High Tibial Osteotomy: A Review
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作者 Mohammad Jawed Aqil Liyong Gang +2 位作者 Abdul Qadir Nawabi Jinan Wei Nasir Ahmad Haidari 《Open Journal of Orthopedics》 2020年第5期93-109,共17页
Main intention of the research is to understand about significance of techniques associated with HTO. This research reviewed the techniques of high tibial osteotomy namely high tibial osteotomy, open wedge high tibial... Main intention of the research is to understand about significance of techniques associated with HTO. This research reviewed the techniques of high tibial osteotomy namely high tibial osteotomy, open wedge high tibial osteotomy, closedhigh tibial osteotomy. Patients who are suffering from knee arthritis, high tibial osteotomy assists to prevent or delay the requirement for total or partial replacement of knee to preserve damaged tissue of joint. High tibial osteotomy technique is mainly suitable for active and young patients with knee osteoarthritis. Age plays a main factor in success rate of high tibial osteotomy technique. It could be done in open wedge or closed wedge high tibial osteotomy. For some cases, surgery could be done in combined method (open wedge and closed wedge high tibial osteotomy). When compared with clinical outcomes of closed wedge high tibial osteotomy and open wedge high tibial osteotomy, open wedge high tibial osteotomy performs well in reducing the pain, duration of weight-bearing and return to normal life as soon as possible. 展开更多
关键词 high tibial osteotomy Open WEDGE high tibial osteotomy KNEE OSTEOARTHRITIS Closed WEDGE high tibial osteotomy
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Biomechanical Stability of Open-Wedge High Tibial Osteotomy: Comparison of Two Locking Plates
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作者 Kota Watanabe Tomoaki Kamiya +4 位作者 Daisuke Suzuki Hidenori Otsubo Atsushi Teramoto Tomoyuki Suzuki Toshihiko Yamashita 《Open Journal of Orthopedics》 2014年第10期257-262,共6页
Introduction: Recently, new plates with locking screws have been developed and used for medial open-wedge high tibial osteotomy (HTO). The purpose of this study was to evaluate and compare biomechanical properties of ... Introduction: Recently, new plates with locking screws have been developed and used for medial open-wedge high tibial osteotomy (HTO). The purpose of this study was to evaluate and compare biomechanical properties of different internal fixations in open-wedge HTO using the two currently available locking plates. Methods: Eight paired fresh-frozen cadaveric lower extremities were vertically embedded in steel boxes. The axial compression load was applied to the legs using the mechanical testing machine. The axial compression load test from 0 N to 550 N and the failure test were performed before and after HTO. One side of the leg of a specimen was fixed with the Puddu locking plate and the other side was fixed with the TomoFix plate to compare the two plates using the same specimen. A mode of failure and vertical displacement of the medial and lateral parts of the tibia at the osteotomy gap was recorded using a video camera in the failure test. The load–displacement data were analyzed to calculate stiffness, failure load, and displacement at failure. Results: The mean failure load was 1471.4 N and 1692.3 N and total vertical displacement at failure was 3.1 mm and 2.9 mm with the Puddu and TomoFix plates, respectively. During axial compression loading, displacements mainly occurred at the lateral osteotomy gap, while the medial gap was well preserved. No significant differences were observed in the failure load, displacement, or mode of failure between the two plates. Conclusions: The Puddu and TomoFix plates had similar biomechanical properties in open-wedge HTO. The results indicated reliable stability after open-wedge HTO without fibular osteotomy. 展开更多
关键词 high tibial osteotomy Puddu Plate TomoFix CADAVER BIOMECHANICS
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Acute Correction of Varus Knee by Biplanar Medial Opening-Wedge High Tibial Osteotomy and Fixation with TomoFix Plate
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作者 Elsayed Shaheen Mohamed Abdel-Aal Morsy 《Open Journal of Orthopedics》 2019年第4期89-100,共12页
Background: Biplanar medial opening wedge high tibial osteotomy (MOWHTO) is a treatment method that allows adequate correction of symptomatic varus knee deformity. However, MOWHTO tends to decrease patellar height and... Background: Biplanar medial opening wedge high tibial osteotomy (MOWHTO) is a treatment method that allows adequate correction of symptomatic varus knee deformity. However, MOWHTO tends to decrease patellar height and increase the posterior tibial slope, which can affect the knee joint stability. Objective: The aim of this study was to describe the technique of biplanar MOWHTO and fixation by TomoFix plate, as well as to evaluate the accuracy of the planned correction and the postoperative tibial slope. Patients and Methods: This prospective cohort study was conducted on patients who presented with varus knee deformity and underwent biplanar MOWHTO and fixation by TomoFix plate during the period from March 2016 to March 2017. Assessment of patients included pre- and postoperative Knee and function scores, mechanical femorotibial angle (mFTA), posterior tibial slope angle (pTSA), range of motion (ROM) and radiological evaluation of the healing of the osteotomy site. Results: The recruited patients were 13 (8 men and 5 women), with average age 31.7 years old. The knee and functional scores improved from the preoperative mean of 45 and 41 to the postoperative mean of 85 and 72 points, respectively. The average knee flexion was 115 degrees, which at the final follow-up remained unchanged except for one case. The mean preoperative mFTA was 13.5&deg;varus and decreased post-operatively to a mean of 3&deg;valgus. The average postoperative follow-up period was 12 months (10 - 18 M). Conclusion: The biplanar MOWHTO allows preservation of posterior tibial slope while correcting the varus knee adequately. 展开更多
关键词 VARUS KNEE Biplanar MEDIAL Opening-Wedge high tibial osteotomy TomoFix PLATE
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Application of 3D printed patient-specific instrumentation in distal tibial tuberosity-high tibial osteotomy
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作者 Ye-Tong Tan Xiang-Dong Tian +7 位作者 Jian Wang Guang-Yu Zhu Sheng Ma Yuan-Yi Hu Chang-Xiao Han Han-Dong Chen Ye Huang Tian-Song Ding 《Journal of Hainan Medical University》 2021年第21期22-27,共6页
Objective:To observe the clinical efficacy and advantages of 3D printed patient-specific instrumentation(PSI)assisted distal tibial tuberosity-high tibial osteotomy in the treatment of medial compartment knee osteoart... Objective:To observe the clinical efficacy and advantages of 3D printed patient-specific instrumentation(PSI)assisted distal tibial tuberosity-high tibial osteotomy in the treatment of medial compartment knee osteoarthritis.Methods:75 patients with medial compartment knee osteoarthritis were included in the study performed DTT-HTO in our hospital from August 2017 to August 2019.The patients were divided into the PSI group(n=39)and conventional group(n=36)According to whether PSI was used in surgery.The differences of lateral cortical fracture rate,time of intraoperative X-ray exposure,intraoperative blood loss,operative time,weight bearing line(WBL),Posterior tibial slope(PTS)and Caton-Deschamps index(CDI)were compared between the two groups.Visual analogue scale(VAS)scores and Hospital for Special Surgery(HSS)scores were recorded to evaluate knee pain and function before surgery and after surgery at 3 months and 12 months.Results:All 75 patients were followed up for more than 12 months,the ranged from 12-26(18.74±6.21)months.Three lateral cortical fractures in the conventional group and no fracture in PSI group.The lateral cortical fracture rate,time of intraoperative X-ray exposure,intraoperative blood loss,operative time in PSI group were lower than those in conventional group(p敿0.05).WBL in two groups were significantly improved after surgery(p敿0.05),and PTS,CDI were no statistically improved after surgery(p>0.05).While there was no statistically significant difference with WBL,PTS and CDI between two groups(p>0.05).At 1 months,3 months and 12 months after surgery;VAS and HSS scores in both groups were significantly improved compared with that before surgery(p0.05),and were no statistically significant difference between two groups.Conclusion:3D printed patient-specific instrumentation assisted DTT-HTO has significant clinical efficacy,and effectively standardized surgical procedures,meanwhile reduced the time of intraoperative X-ray exposure,intraoperative blood loss and risk of lateral cortical fracture. 展开更多
关键词 high tibial osteotomy Three-dimensional printing Patient-specific instrumentation Medial compartment knee osteoarthritis
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关节镜下松解深层内侧副韧带联合HTO治疗对膝内侧间室骨关节炎患者膝关节活动情况的影响研究
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作者 周全 李伟伟 +1 位作者 叶昊 朱帆 《中外医疗》 2024年第16期47-50,共4页
目的 分析关节镜下松解深层内侧副韧带联合胫骨高位截骨术(High Tibial Osteotomy, HTO)治疗对膝内侧间室骨关节炎患者膝关节活动情况的影响。方法 回顾性选取京山市人民医院于2021年5月—2023年5月收治的106例膝内侧间室骨关节炎患者... 目的 分析关节镜下松解深层内侧副韧带联合胫骨高位截骨术(High Tibial Osteotomy, HTO)治疗对膝内侧间室骨关节炎患者膝关节活动情况的影响。方法 回顾性选取京山市人民医院于2021年5月—2023年5月收治的106例膝内侧间室骨关节炎患者的临床资料,依治疗方式不同分为研究组(关节镜下松解深层内侧副韧带联合胫骨高位截骨术)和对照组(关节镜下松解浅层内侧副韧带联合胫骨高位截骨术),各53例。对比两组临床疗效、膝关节功能评分及并发症发生情况。结果 研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。术后1、3个月,研究组膝关节功能评分为(62.66±1.32)分、(82.65±2.31)分,高于对照组的(59.76±2.13)分、(76.54±3.11)分,差异有统计学意义(t=8.425、11.482,P均<0.05)。两组并发症发生率对比,差异无统计学意义(P>0.05)。结论 针对膝内侧间室骨关节炎患者,于HTO术中增加关节镜下松解深层内侧副韧带,可改善膝关节功能,疗效更佳。 展开更多
关键词 胫骨高位截骨术 关节镜 深层内侧副韧带 膝内侧间室骨关节炎
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OWHTO与UKA对膝关节内侧间室骨关节炎的临床疗效 被引量:1
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作者 张江礼 刘金辉 +2 位作者 潘西庆 刘光源 范虓 《中外医学研究》 2023年第22期1-5,共5页
目的:比较膝关节内侧间室骨关节炎患者应用开放楔形胫骨高位截骨术(OWHTO)与单髁置换术(UKA)治疗的效果。方法:选取2019年4月-2022年4月石家庄市第三医院收治的110例膝关节内侧间室骨关节炎患者作为研究对象,按随机数表法将其分为对照... 目的:比较膝关节内侧间室骨关节炎患者应用开放楔形胫骨高位截骨术(OWHTO)与单髁置换术(UKA)治疗的效果。方法:选取2019年4月-2022年4月石家庄市第三医院收治的110例膝关节内侧间室骨关节炎患者作为研究对象,按随机数表法将其分为对照组和观察组,各55例。对照组给予UKA治疗,观察组给予OWHTO治疗,比较两组手术相关指标,以及术前、术后3个月视觉模拟评分法(VAS)评分、膝关节功能、屈膝最大角度及髌骨高度。结果:观察组手术时间、住院时间均长于对照组,术中出血量多于对照组,差异有统计学意义(P<0.05)。术前,两组VAS评分、膝关节功能、屈膝最大角度、髌骨高度比较,差异无统计学意义(P>0.05);术后3个月,两组VAS评分、胫股角(FTA)水平低于术前,且观察组低于对照组,美国特种外科医院膝关节评分(HSS)、胫骨后倾角(PTS)水平高于术前,且观察组高于对照组,差异有统计学意义(P<0.05);术后3个月,两组Insall-Salvati指数(ISI)、Caton-Deschamps指数(CDI)及Blackburn-Peel指数(BPI)均低于术前,但观察组高于对照组,差异有统计学意义(P<0.05)。结论:相较于UKA,膝关节内侧间室骨关节炎患者采用OWHTO治疗,虽其手术时间、住院时间与术中出血量均更大,但可有效降低患者疼痛度,明显促进膝关节功能恢复,获得显著的疗效。 展开更多
关键词 膝关节内侧间室骨关节炎 开放楔形胫骨高位截骨术 单髁置换术
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关节镜下清理术联合胫骨高位截骨术(HTO)对中早期内翻型膝关节骨性关节炎疾病的治疗效果
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作者 顾俊峰 翁献 +1 位作者 戴小青 韩恒宽 《系统医学》 2023年第15期50-53,共4页
目的分析关节镜下清理术联合胫骨高位截骨术(high tibial osteotomy,HTO)对中早期内翻型膝关节骨性关节炎(knee osteoarthritis,KOA)的治疗效果。方法选取2020年1月—2022年12月期间常熟市第五人民医院骨科收治的60例中早期内翻型KOA患... 目的分析关节镜下清理术联合胫骨高位截骨术(high tibial osteotomy,HTO)对中早期内翻型膝关节骨性关节炎(knee osteoarthritis,KOA)的治疗效果。方法选取2020年1月—2022年12月期间常熟市第五人民医院骨科收治的60例中早期内翻型KOA患者为研究对象,随机抽签均分为两组,每组30例。对照组采用关节镜下清理术进行治疗,研究组采用关节镜下清理术联合HTO进行治疗。对比两组治疗效果。结果研究组术后疼痛评分为(2.45±1.28)分,低于对照组(4.76±1.45)分,差异有统计学意义(t=6.542,P<0.05)。研究组治疗优良率为96.67%,高于对照组,差异有统计学意义(P<0.05)。对照组术后不良反应发生率高于研究组,差异有统计学意义(P<0.05)。术前,两组生活质量水平比较,差异无统计学意义(P>0.05);术后,研究组生活质量水平优于对照组,差异有统计学意义(P<0.05)。结论对中早期内翻型KOA患者采用关节镜下清理术联合HTO,有利于提高患者治疗有效率,减少不良反应的出现,提升患者术后生活质量水平。 展开更多
关键词 膝关节骨性关节炎 内翻型 关节镜下胫骨高位截骨术 术后疼痛 生活质量 不良反应
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Proximal tibial osteotomy for genu varum:Radiological evaluation of deformity correction with a plate vs external fixator 被引量:1
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作者 S Ali Ghasemi David T Zhang +1 位作者 Austin Fragomen S Robert Rozbruch 《World Journal of Orthopedics》 2021年第3期140-151,共12页
BACKGROUND High tibial osteotomy(HTO)is a well-known procedure for the correction of knee varus.The purpose of this study was to compare the radiological results and accuracy of deformity correction performed using tw... BACKGROUND High tibial osteotomy(HTO)is a well-known procedure for the correction of knee varus.The purpose of this study was to compare the radiological results and accuracy of deformity correction performed using two different techniques:acute opening wedge correction using a plate and gradual correction with a monolateral external fixator.AIM To compare of the radiological results of two different techniques:acute opening wedge correction(a plate and screw)and gradual correction(external fixator).METHODS A total of 43 patients with plates and 36 patients with external fixators were included.All patients had moderate uniplanar varus deformities.We measured radiographic parameters,including the mechanical axis deviation(MAD),medial proximal tibial angle(MPTA),Caton-Deschamps Index(CDI),posterior proximal tibial angle,and joint line obliquity angle(JLOA).The accuracy of MAD correction was calculated based on a correction goal of neutral or overcorrection for medial compartment arthritis.RESULTS Demographics including age,body mass index,sex,and preoperative deformities were similar between the groups.The MAD significantly improved from 23.6 mm medial to the midline(SD=8.2 mm)to 6.9 mm lateral to the midline(SD=5.4 mm)(P<0.001).The accuracy of MAD correction did not differ between the groups and was 96.1%(SD=8.1%)in the plate group and 98.2%(SD=5.2%)in the external fixator group(P=0.18).The MPTA significantly improved from 83.9°(SD=2.9°)to 90.9°(SD=3.3°)(P<0.001),and the change was similar between the groups.Differences were noted in patella height,with a CDI change of-19.2%(SD=13.7%)and 3.1%(SD=8.0%)for the plate and external fixator groups,respectively(P<0.001).The change in JLOA was 1.6 degrees(SD=1.1 degrees)and 0.9 degrees(SD=0.9 degrees)for the plate and external fixator groups,respectively(P=0.04).CONCLUSION Reliable correction of moderate varus alignment was achieved with both the acute opening wedge technique with a plate and the gradual monolateral external fixator technique.The patellar height decreased with the open wedge plate technique.Joint line obliquity decreased to a greater degree with the open wedge plate technique,perhaps as a result of medial collateral ligament release.The appropriate technique should be selected based on surgeon and patient preferences;however,external fixation may be a better choice when the preservation of patellar height is deemed important. 展开更多
关键词 high tibial osteotomy External fixator Gradual correction Plate and screw Genu varum RADIOLOGICAL
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HTO联合膝关节镜治疗膝骨关节炎的早期疗效观察 被引量:2
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作者 刘明星 郝杰 +3 位作者 李松林 苗壮 韩凯飞 刘培来 《实用骨科杂志》 2023年第10期912-915,共4页
目的 探究应用胫骨高位截骨术(high tibial osteotomy, HTO)联合膝关节镜治疗膝关节骨关节炎术后早期疗效。方法 选取2020年7月至2021年6月间因膝关节骨关节炎于山东大学齐鲁医院关节科行HTO治疗的25例患者,男性11例,女性14例;年龄47~65... 目的 探究应用胫骨高位截骨术(high tibial osteotomy, HTO)联合膝关节镜治疗膝关节骨关节炎术后早期疗效。方法 选取2020年7月至2021年6月间因膝关节骨关节炎于山东大学齐鲁医院关节科行HTO治疗的25例患者,男性11例,女性14例;年龄47~65岁,平均(53.84±5.08)岁,记录术前及术后血液指标变化、术中出血量及术后引流量、并发症等发生情况。于术后6周、术后3个月、术后6个月随访,采用疼痛视觉模拟评分(visual analogue scale, VAS)及美国特种外科医院(hospital for special surgery, HSS)膝关节评分评定膝关节功能及疗效。结果 所有患者均顺利完成手术,术中及术后均无严重并发症发生。术前、术后部分血液学指标差异有统计学意义。术前VAS评分(6.52±1.16)分,术后6个月(0.92±0.76)分,两者比较差异有统计学意义(P<0.05);术前HSS评分(75.16±5.42)分,术后6个月(92.36±2.84)分,两者比较差异有统计学意义(P<0.05)。结论 HTO联合膝关节镜治疗膝关节骨关节炎,术中缺血少,早期膝关节功能明显改善,值得临床推广应用。 展开更多
关键词 胫骨高位截骨术 膝骨关节炎 膝关节镜 早期疗效
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HIGH TIBIA OSTEOTOMY WITH KOSHINO TECHNIQUE FOR MEDIAL PATELLOFEMORAL OSTEOARTHRITIS OF THE KNEE
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作者 蒋垚 钱不凡 +2 位作者 杨庆铭 何国础 王毅 《Medical Bulletin of Shanghai Jiaotong University》 CAS 1993年第2期18-25,共8页
From March 1988 to March 1992, a total of 40 high tibial osteotomies(HTO) were performed according to Koshino technique in 35 patients, suffering fromosteoarthritis of knee joints. There were 9 male and 26 female pati... From March 1988 to March 1992, a total of 40 high tibial osteotomies(HTO) were performed according to Koshino technique in 35 patients, suffering fromosteoarthritis of knee joints. There were 9 male and 26 female patients. The right kneeand left knee were involved in 15 cases each and both knees involved in 5 cases. The ageof the patients ranged from 33 to 75 years with an average of 58. 6 years. Allosteoarthritis of knee joint were primary except 4 patients with secondary disease due toupper tibiai fracture in the past. According to the classification of knee osteoarthritis ofthe Yokohama City University in Japan, all our patients suffered from medialpatellofemoral type of knee osteoarthritis. On the basis of the pre-operative evaluation ofknee function with the Yokohama City University criteria, the patients had from 40 pointsto 65 points with an average of 53 points. The femoro-tibial angles (FTA) before opera-tion wcre from 178°to 192°with an average of 185.1°±4.7°. The size of bone wedgeto be removed was accurately calculated so as to produce a femoro-tibial angle of 170°after operation, giving 10°of valgus. In severe cases the exposed bone and cartilage ero-sion were found during the operation. In knees with deformity adequately corrected,marked relief of pain was obtained and walking resumed by 4-6 months after operation.The post-operative follow-up ranged from 6 months to 2 years and 3 months with an av-erage of 14.2 months. Out of the 40 patients 17 had their implant removed over a year.Early complications, such as wound infection, hematoma, joint adhesion, deep-veinthrombosis or non-union of bone, did not occur. The post-operative FTA ranged from166°to 177°with an average of 170.3°±3.7°. Post-operative evaluating showed kneefunction from 75 points to 95 points with an average of 88 points, implying good func-tional results. We consider that the Koshino technique of high tibial osteotomy has manyadvantages. It is suited to medial and medial patello-femoral osteoarthritis of the kneejoint. 展开更多
关键词 knee osteoarthritis Koshino high tibial osteotomy
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HTO、UKA及TKA治疗单间室膝关节骨性关节炎的早期临床疗效对比研究 被引量:3
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作者 赵寅 秦光华 姚剑南 《罕少疾病杂志》 2023年第4期79-81,共3页
目的探讨胫骨高位截骨术(HTO)、全膝关节置换术(TKA)、单髁置换术(UKA)治疗单间室膝关节骨性关节炎(KOA)的效果。方法选取2020年1月-2021年12月我院117例单间室KOA患者临床资料进行回顾性分析,根据不同手术方式分组,各39例。UKA组行UKA... 目的探讨胫骨高位截骨术(HTO)、全膝关节置换术(TKA)、单髁置换术(UKA)治疗单间室膝关节骨性关节炎(KOA)的效果。方法选取2020年1月-2021年12月我院117例单间室KOA患者临床资料进行回顾性分析,根据不同手术方式分组,各39例。UKA组行UKA术,TKA组行TKA术,HTO组行HTO术。比较三组临床指标、并发症发生率及术前、术后3个月美国特种外科医院膝关节评分(HSS)、步行速度及膝关节活动度(ROM)变化。结果住院时间、下地时间UKA组较TKA组、HTO组短,术中出血量UKA组较TKA组、HTO组少,手术时间HTO组较UKA组、TKA组短(P<0.05);术后3个月UKA组、HTO组HSS评分较TKA组高,HTO组步行速度及ROM较UKA组、TKA组高,且UKA组步行速度高于TKA组(P<0.05);UKA组并发症发生率低于TKA组、HTO组(P<0.05)。结论HTO术、UKA术与TKA术各有优缺点,HTO术在改善关节活动度,提高患者运动功能具有独特优势,更适宜于年轻患者;而UKA术则因其较短的康复周期、良好的功能改善更适应于老年患者。临床应结合实际情况,严格筛选病例,合理选择手术方式。 展开更多
关键词 膝关节骨性关节炎 全膝关节置换术 单髁置换术 胫骨高位截骨术
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氨甲环酸不同使用方法在胫骨高位截骨过程中的安全及有效性
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作者 杜长岭 石辉 +5 位作者 张寿涛 孟涛 刘栋 李健 曹恒 徐闯 《中国组织工程研究》 CAS 北大核心 2024年第9期1409-1413,共5页
背景:胫骨高位截骨围术期会产生大量失血现象,应用氨甲环酸可有效降低围术期失血量,但关于氨甲环酸的应用方式尚未达成共识。目的:探讨在胫骨高位截骨过程中应用不同方法给予氨甲环酸对围术期止血效果及安全性的影响。方法:选择2019年1... 背景:胫骨高位截骨围术期会产生大量失血现象,应用氨甲环酸可有效降低围术期失血量,但关于氨甲环酸的应用方式尚未达成共识。目的:探讨在胫骨高位截骨过程中应用不同方法给予氨甲环酸对围术期止血效果及安全性的影响。方法:选择2019年1月至2021年12月就诊于滨州医学院附属医院行初次单侧胫骨高位截骨术患者共160例,其中男69例,女91例,采用随机数字表法分为4组,其中40例患者松止血带之前10 min予以静滴氨甲环酸2 g(静脉组),40例予以静滴氨甲环酸1 g,关闭切口后引流管内灌注氨甲环酸1 g(联合组),40例予以关闭切口后引流管内灌注氨甲环酸2 g(灌注组),另40例予以静滴等量生理盐水(空白组)。比较4组患者围术期的一般资料,记录4组患者术后第1,3,5天血红蛋白及红细胞压积、术中出血量、引流量、输血情况、切口并发症及静脉血栓形成情况,计算总失血量、隐性出血量。结果与结论:①4组患者术前一般资料比较差异均无显著性意义;②术中出血量组间比较差异无显著性意义;③术后第1,3,5天血红蛋白及红细胞压积最大下降值均为联合组<静脉组<灌注组<空白组;引流量、总失血量、隐性出血量均为联合组<静脉组<灌注组<空白组;④空白组术后输血率均高于其他3组,差异有显著性意义;联合组、静脉组与灌注组术后输血率组间比较差异无显著性意义;⑤4组患者术后静脉血栓形成情况、术后切口并发症比较差异无显著性意义;⑥提示:在胫骨高位截骨术中应用氨甲环酸对减少围术期出血和降低术后输血率有显著作用,不增加下肢静脉血栓和切口并发症发生率,静脉输液联合引流管灌注效果更佳。 展开更多
关键词 膝关节骨性关节炎 胫骨高位截骨术 氨甲环酸 灌注 失血量 并发症
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胫骨内侧高位截骨术治疗膝骨关节炎的疗效及对膝关节外侧间室软骨病变的影响
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作者 苏柯 王庆海 +3 位作者 桑卫华 王军 马世云 靳胜利 《临床骨科杂志》 2024年第2期204-208,共5页
目的探讨胫骨内侧高位截骨术治疗膝骨关节炎的疗效及对膝关节外侧间室软骨病变的影响。方法采用胫骨内侧高位截骨术治疗104例单侧内翻型膝骨关节炎患者,取出内固定时再次行关节镜探查膝关节外侧间室的软骨病变进展。根据截骨术时膝关节... 目的探讨胫骨内侧高位截骨术治疗膝骨关节炎的疗效及对膝关节外侧间室软骨病变的影响。方法采用胫骨内侧高位截骨术治疗104例单侧内翻型膝骨关节炎患者,取出内固定时再次行关节镜探查膝关节外侧间室的软骨病变进展。根据截骨术时膝关节外侧间室软骨病变分级将患者分为A组(OuterbridgeⅠ度,41例)、B组(OuterbridgeⅡ度,35例)、C组(OuterbridgeⅢ度,28例)。记录疼痛VAS评分、Lysholm评分、WOMAC评分、再次手术时膝关节外侧间室软骨病变的变化。结果患者均获得随访,时间12~32(20.19±4.65)个月。3组疼痛VAS评分、Lysholm评分和WOMAC评分再次手术前均较初次手术前改善(P<0.05)。再次手术前,疼痛VAS评分A组和B组比较差异无统计学意义(P>0.05),且均优于C组(P<0.05);3组Lysholm评分和WOMAC评分比较差异均无统计学意义(P>0.05)。3组膝关节外侧间室软骨病变最大直径再次手术时与初次手术时比较差异均无统计学意义(P>0.05)。结论对膝关节外侧间室软骨OuterbridgeⅠ~Ⅲ度病变患者行胫骨内侧高位截骨术,不会增加外侧间室的软骨退变,仍能获得较为满意的临床效果。 展开更多
关键词 胫骨高位截骨 膝骨关节炎 膝内翻 关节镜检查
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关节镜联合胫骨高位截骨术治疗膝关节内侧间室骨关节炎的效果分析
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作者 段晓东 张凯 +1 位作者 蔡长马 张磊 《中国社区医师》 2024年第2期43-45,共3页
目的:分析关节镜联合胫骨高位截骨术治疗膝关节内侧间室骨关节炎的效果。方法:选取2020年1月—2021年1月滨州市中心医院收治的100例膝关节内侧间室骨关节炎患者作为研究对象,随机分为观察组与对照组,各50例。对照组采取单纯关节镜下清... 目的:分析关节镜联合胫骨高位截骨术治疗膝关节内侧间室骨关节炎的效果。方法:选取2020年1月—2021年1月滨州市中心医院收治的100例膝关节内侧间室骨关节炎患者作为研究对象,随机分为观察组与对照组,各50例。对照组采取单纯关节镜下清理术治疗,观察组采取关节镜联合胫骨高位截骨术治疗。比较两组临床疗效。结果:术前,两组视觉模拟评分法(VAS)、Lysholm膝关节量表、美国纽约特种外科医院量表(HSS)评分比较,差异无统计学意义(P>0.05);手术12个月后,两组VAS评分低于手术前,且观察组低于对照组,两组Lysholm、HSS评分高于手术前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.001)。结论:关节镜联合胫骨高位截骨术治疗膝关节内侧间室骨关节炎的效果较好,患者疼痛轻,膝关节功能恢复好,并发症发生率低。 展开更多
关键词 关节镜 胫骨高位截骨术 膝关节 骨关节炎
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基于下肢全长X线片及CT平扫探讨鹅足肌腱对胫骨高位截骨术后胫骨远端轴位旋转的影响
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作者 荆立忠 杨久山 《中国中西医结合影像学杂志》 2024年第5期594-598,共5页
目的:基于下肢全长X线片及CT平扫探讨内侧开放楔形胫骨高位截骨术(MOWHTO)后鹅足肌腱的有无对胫骨远端相对于胫骨近端轴位旋转的影响。方法:回顾性收集行MOWHTO的患者63例,根据术中对鹅足肌腱的处理情况,分为未松解组(对照组)、部分松解... 目的:基于下肢全长X线片及CT平扫探讨内侧开放楔形胫骨高位截骨术(MOWHTO)后鹅足肌腱的有无对胫骨远端相对于胫骨近端轴位旋转的影响。方法:回顾性收集行MOWHTO的患者63例,根据术中对鹅足肌腱的处理情况,分为未松解组(对照组)、部分松解组(观察组1)和完全松解组(观察组2)各21例(21膝);同时收集自体腘绳肌腱行前交叉韧带重建的患者(观察组3)21例(21膝)。患者术前及术后1周内均行下肢全长正侧位X线检查及髋膝踝CT平扫,测量解剖股骨胫骨角(aFTA)、胫骨近端内侧角(MPTA)和胫骨扭转角(TTA),并进行比较。结果:观察组1、观察组2、观察组3及对照组aFTA分别由术前(180.85±2.51)°、(180.30±2.18)°、(181.01±2.06)°和(181.34±1.98)°,矫正为术后(173.85±1.83)°、(174.11±1.34)°、(173.33±1.56)°和(174.26±1.77)°;MPTA由术前(80.23±1.83)°、(79.37±1.62)°、(81.01±1.52)°和(80.90±1.37)°,矫正为术后(89.54±2.33)°、(88.26±1.89)°、(87.58±1.01)°和(88.42±1.25)°。4组间术前aFTA、术后aFTA、术前MPTA、术后MPTA的差异均无统计学意义(均P>0.05);4组术后与术前TTA差值分别为(-0.52±0.99)°、(-0.07±2.06)°、(-0.13±1.37)°和(-0.89±1.21)°,观察组2、观察组3与对照组相比,差异均有统计学意义(均P<0.05)。结论:完整的鹅足肌腱可导致MOWHTO后胫骨远端相对于胫骨近端内旋,对其进行松解会削弱此作用,在MOWHTO中需合理处理鹅足肌腱,以尽量避免非计划的胫骨扭转。 展开更多
关键词 胫骨高位截骨术 鹅足肌腱 前交叉韧带重建 胫骨扭转 体层摄影术 X线计算机 放射摄影术
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胫骨高位截骨术治疗老年膝关节内侧间室炎的疗效研究 被引量:1
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作者 杨泽宇 邹灵 +4 位作者 孙长惠 陆炯 陈一南 何沁 胡旻炜 《实用老年医学》 CAS 2024年第1期59-63,共5页
目的 比较胫骨高位截骨术(high tibial osteotomy, HTO)治疗老年与非老年膝关节内侧间室炎的疗效。方法 回顾性分析26例接受HTO手术病人的临床资料,按照病人年龄分为≥60岁组(n=18)和<60岁组(n=8)。比较2组一般资料、手术截骨撑开角... 目的 比较胫骨高位截骨术(high tibial osteotomy, HTO)治疗老年与非老年膝关节内侧间室炎的疗效。方法 回顾性分析26例接受HTO手术病人的临床资料,按照病人年龄分为≥60岁组(n=18)和<60岁组(n=8)。比较2组一般资料、手术截骨撑开角度及并发症发生情况,比较2组术前及术后1年VAS、膝关节功能评分量表(Knee Injury and Osteoarthritis Outcome Score, KOOS)各项评分。结果 2组性别、Kellgren-Lawrence(K-L)评级、BMI、手术截骨撑开角度、并发症发生率差异均无统计学意义(P>0.01)。2组术后1年VAS及KOOS各项评分均较术前明显改善(P<0.01)。术前及术后1年2组间VAS、KOOS各项评分差异均无统计学意义(P>0.01)。结论 HTO是一种安全且高效的膝关节内侧间室炎治疗手段,对于60岁及以上老年病人同样安全有效。 展开更多
关键词 膝关节炎 膝关节内侧间室炎 胫骨高位截骨术 老年人
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关节镜联合胫骨高位截骨术对髌骨位置及髌股关节功能影响的早中期回顾性研究 被引量:1
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作者 庄万强 唐毅 +1 位作者 骆勇刚 张辉 《中国临床解剖学杂志》 CSCD 北大核心 2024年第1期77-82,共6页
目的探讨髌骨位置的改变是否会对髌股关节和功能产生不利影响。方法回顾性纳入2018年03月-2021年03月于本研究中心接受关节镜联合胫骨高位截骨术的患者。初次手术和内固定取出过程中进行关节镜诊断,比较各关节软骨状况及临床结果,采取... 目的探讨髌骨位置的改变是否会对髌股关节和功能产生不利影响。方法回顾性纳入2018年03月-2021年03月于本研究中心接受关节镜联合胫骨高位截骨术的患者。初次手术和内固定取出过程中进行关节镜诊断,比较各关节软骨状况及临床结果,采取影像学测量,评估髌骨位置变化。探究关节软骨状态与功能的关系。结果共纳入接受关节镜联合胫骨高位截骨术的患者60名,其中男性18例,女性42例,平均年龄(58.6±7.2)岁,平均随访时间(26.8±8.5)月。患者接受手术后,髌骨高度InsallSalvati Index并无统计学差异,Blackburne-Peel index指数由术前的(0.90±0.11)变为(0.81±0.13)。通过二次关节镜检查,依据国际软骨修复协会软骨损伤评分系统评估,股骨内侧髁的软骨状况从3.81改善至3.35(P=0.005),胫骨内侧平台的软骨状况从3.75改善至3.48(P=0.005)。股骨外侧髁的平均ICRS评分从0.15下降到0.43(P=0.004),胫骨外侧髁的平均ICRS评分从0.38下降到0.96(P<0.001)。髌骨侧平均ICRS分级为2.29~2.31,股骨滑车平均ICRS分级为2.18~2.25。膝关节功能评分较术前明显改善。结论关节镜联合胫骨高位截骨术后,尽管髌骨位置会出现影像学改变,但髌股关节软骨未见明显损伤及退化,膝关节功能尤其髌股关节功能未受到髌骨位置改变影响。 展开更多
关键词 关节镜联合胫骨高位截骨术 髌骨位置 关节软骨
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