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Nogo-A Protein Mediates Oxidative Stress and Synaptic Damage Induced by High-Altitude Hypoxia in the Rat Hippocampus
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作者 Jinyu Fang Huaicun Liu +6 位作者 Yanfei Zhang Quancheng Cheng Ziyuan Wang Xuan Fang Huiru Ding Weiguang Zhang Chunhua Chen 《Biomedical and Environmental Sciences》 2025年第1期79-93,共15页
Objective High-altitude hypoxia exposure often damages hippocampus-dependent learning and memory.Nogo-A is an important axonal growth inhibitory factor.However,its function in high-altitude hypoxia and its mechanism o... Objective High-altitude hypoxia exposure often damages hippocampus-dependent learning and memory.Nogo-A is an important axonal growth inhibitory factor.However,its function in high-altitude hypoxia and its mechanism of action remain unclear.Methods In an in vivo study,a low-pressure oxygen chamber was used to simulate high-altitude hypoxia,and genetic or pharmacological intervention was used to block the Nogo-A/NgR1 signaling pathway.Contextual fear conditioning and Morris water maze behavioral tests were used to assess learning and memory in rats,and synaptic damage in the hippocampus and changes in oxidative stress levels were observed.In vitro,SH-SY5Y cells were used to assess oxidative stress and mitochondrial function with or without Nogo-A knockdown in Oxygen Glucose-Deprivation/Reperfusion(OGD/R)models.Results Exposure to acute high-altitude hypoxia for 3 or 7 days impaired learning and memory in rats,triggered oxidative stress in the hippocampal tissue,and reduced the dendritic spine density of hippocampal neurons.Blocking the Nogo-A/NgR1 pathway ameliorated oxidative stress,synaptic damage,and the learning and memory impairment induced by high-altitude exposure.Conclusion Our results demonstrate the detrimental role of Nogo-A protein in mediating learning and memory impairment under high-altitude hypoxia and suggest the potential of the Nogo-A/NgR1 signaling pathway as a crucial therapeutic target for alleviating learning and memory dysfunction induced by high-altitude exposure. 展开更多
关键词 NOGO-A NgR1 high-altitude hypoxia Learning and memory Oxidative stress
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Experimental and numerical simulation of the attenuation effect of blast shock waves in tunnels at different altitudes
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作者 Changjiang Liu Hujun Li +3 位作者 Zhen Wang Yong He Guokai Zhang Mingyang Wang 《Defence Technology(防务技术)》 2025年第1期120-141,共22页
Traffic engineering such as tunnels in various altitudinal gradient zone are at risk of accidental explosion,which can damage personnel and equipment.Accurate prediction of the distribution pattern of explosive loads ... Traffic engineering such as tunnels in various altitudinal gradient zone are at risk of accidental explosion,which can damage personnel and equipment.Accurate prediction of the distribution pattern of explosive loads and shock wave propagation process in semi-enclosed structures at various altitude environment is key research focus in the fields of explosion shock and fluid dynamics.The effect of altitude on the propagation of shock waves in tunnels was investigated by conducting explosion test and numerical simulation.Based on the experimental and numerical simulation results,a prediction model for the attenuation of the peak overpressure of tunnel shock waves at different altitudes was established.The results showed that the peak overpressure decreased at the same measurement points in the tunnel entrance under the high altitude condition.In contrast,an increase in altitude accelerated the propagation speed of the shock wave in the tunnel.The average error between the peak shock wave overpressure obtained using the overpressure prediction formula and the measured test data was less than15%,the average error between the propagation velocity of shock waves predicted values and the test data is less than 10%.The method can effectively predict the overpressure attenuation of blast wave in tunnel at various altitudes. 展开更多
关键词 Shock wave propagation tunnel Altitude effect Peak overpressure Shock waves velocity Engineering safety
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Analysis of the interaction between bolt-reinforced rock and surface support in tunnels based on convergence-confinement method 被引量:3
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作者 Zhenyu Sun Dingli Zhang +2 位作者 Qian Fang Yanjuan Hou Nanqi Huangfu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期1936-1951,共16页
To investigate the interaction of the bolt-reinforced rock and the surface support,an analytical model of the convergence-confinement type is proposed,considering the sequential installation of the fully grouted rockb... To investigate the interaction of the bolt-reinforced rock and the surface support,an analytical model of the convergence-confinement type is proposed,considering the sequential installation of the fully grouted rockbolts and the surface support.The rock mass is assumed to be elastic-brittle-plastic material,obeying the linear Mohr-Coulomb criterion or the non-linear Hoek-Brown criterion.According to the strain states of the tunnel wall at bolt and surface support installation and the relative magnitude between the bolt length and the plastic depth during the whole process,six cases are categorized upon solving the problem.Each case is divided into three stages due to the different effects of the active rockbolts and the passive surface support.The fictitious pressure is introduced to quantify the threedimensional(3D)effect of the tunnel face,and thus,the actual physical location along the tunnel axis of the analytical section can be considered.By using the bolt-rock strain compatibility and the rocksurface support displacement compatibility conditions,the solutions of longitudinal tunnel displacement and the reaction pressure of surface support along the tunnel axis are obtained.The proposed analytical solutions are validated by a series of 3D numerical simulations.Extensive parametric studies are conducted to examine the effect of the typical parameters of rockbolts and surface support on the tunnel displacement and the reaction pressure of the surface support under different rock conditions.The results show that the rockbolts are more effective in controlling the tunnel displacement than the surface support,which should be installed as soon as possible with a suitable length.For tunnels excavated in weak rocks or with restricted displacement control requirements,the surface support should also be installed or closed timely with a certain stiffness.The proposed method provides a convenient alternative approach for the optimization of rockbolts and surface support at the preliminary stage of tunnel design. 展开更多
关键词 Analytical model Longitudinal tunnel displacement Fictitious pressure Active rockbolts Surface support reaction pressure tunnel design
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Mechanism of high-preload support based on the NPR anchor cable in layered soft rock tunnels 被引量:1
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作者 SUI Qiru HE Manchao +3 位作者 SHI Mengfan TAO Zhigang ZHAO Feifei ZHANG Xiaoyu 《Journal of Mountain Science》 SCIE CSCD 2024年第4期1403-1418,共16页
The control of large deformation problems in layered soft rock tunnels needs to solve urgently.The roof problem is particularly severe among the deformation issues in tunnels.This study first analyzes the asymmetric d... The control of large deformation problems in layered soft rock tunnels needs to solve urgently.The roof problem is particularly severe among the deformation issues in tunnels.This study first analyzes the asymmetric deformation modes in layered soft rock tunnels with large deformations.Subsequently,we construct a mechanical model under ideal conditions for controlling the roof of layered soft rock tunnels through high preload with the support of NPR anchor cables.The prominent roles of long and short NPR anchor cables in the support system are also analyzed.The results indicate the significance of high preload in controlling the roof of layered soft rock tunnels.The short NPR anchor cables effectively improve the integrity of the stratified soft rock layers,while the long NPR anchor cables effectively mobilize the self-bearing capacity of deep-stable rock layers.Finally,the high-preload support method with NPR anchor cables is validated to have a good effect on controlling large deformations in layered soft rock tunnels through field monitoring data. 展开更多
关键词 tunnel engineering Soft rock High-preload support NPR anchor cables
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A methodology for damage evaluation of underground tunnels subjected to static loading using numerical modeling 被引量:1
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作者 Shahriyar Heidarzadeh Ali Saeidi 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期1993-2005,共13页
We have proposed a methodology to assess the robustness of underground tunnels against potential failure.This involves developing vulnerability functions for various qualities of rock mass and static loading intensiti... We have proposed a methodology to assess the robustness of underground tunnels against potential failure.This involves developing vulnerability functions for various qualities of rock mass and static loading intensities.To account for these variations,we utilized a Monte Carlo Simulation(MCS)technique coupled with the finite difference code FLAC^(3D),to conduct two thousand seven hundred numerical simulations of a horseshoe tunnel located within a rock mass with different geological strength index system(GSIs)and subjected to different states of static loading.To quantify the severity of damage within the rock mass,we selected one stress-based(brittle shear ratio(BSR))and one strain-based failure criterion(plastic damage index(PDI)).Based on these criteria,we then developed fragility curves.Additionally,we used mathematical approximation techniques to produce vulnerability functions that relate the probabilities of various damage states to loading intensities for different quality classes of blocky rock mass.The results indicated that the fragility curves we obtained could accurately depict the evolution of the inner and outer shell damage around the tunnel.Therefore,we have provided engineers with a tool that can predict levels of damages associated with different failure mechanisms based on variations in rock mass quality and in situ stress state.Our method is a numerically developed,multi-variate approach that can aid engineers in making informed decisions about the robustness of underground tunnels. 展开更多
关键词 Fragility curves Underground tunnels Vulnerability functions Brittle damage FLAC3D Numerical modeling
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Application of excavation compensation method for enhancing stability and efficiency in shallow large-span rock tunnels
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作者 BIAN Wen-hui YANG Jun +2 位作者 ZHU Chun WANG Ke-xue XU Dong-ming 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第9期3242-3263,共22页
Engineering shallow,large-span rock tunnels challenges deformation control and escalates construction costs.This study investigates the excavation compensation method(ECM)and its associated technologies to address the... Engineering shallow,large-span rock tunnels challenges deformation control and escalates construction costs.This study investigates the excavation compensation method(ECM)and its associated technologies to address these issues.Utilizing five key technologies,the ECM effectively modulates radial stress post-excavation,redistributes stress in the surrounding rock,and eliminates tensile stress at the excavation face.Pre-tensioning measures further enhance the rock’s residual strength,establishing a new stability equilibrium.Field tests corroborate the method’s effectiveness,demonstrating a crown settlement reduction of 3–8 mm,a nearly 50%decrease compared to conventional construction approaches.Additionally,material consumption and construction duration were reduced by approximately 30%–35%and 1.75 months per 100 m,respectively.Thus,the ECM represents a significant innovation in enhancing the stability and construction efficiency of large-span rock tunnels,marking a novel contribution to the engineering field. 展开更多
关键词 excavation compensation method rocky tunnels shallow spanning tunnels tunnel support field test
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Convergent evolution in high-altitude and marine mammals:Molecular adaptations to pulmonary fibrosis and hypoxia
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作者 Bo-Xiong Guo Ya Zhang +5 位作者 Xiao-Yu Sun Yi-Xuan Sun Wen-Jun Lv Shi-Xia Xu Guang Yang Wen-Hua Ren 《Zoological Research》 SCIE CSCD 2024年第6期1209-1220,共12页
High-altitude and marine mammals inhabit distinct ecosystems but share a common challenge:hypoxia.To survive in low-oxygen environments,these species have evolved similar phenotypic pulmonary adaptations,characterized... High-altitude and marine mammals inhabit distinct ecosystems but share a common challenge:hypoxia.To survive in low-oxygen environments,these species have evolved similar phenotypic pulmonary adaptations,characterized by a high density of elastic fibers.In this study,we explored the molecular mechanisms underlying these adaptations,focusing on pulmonary fibrosis and hypoxia tolerance through comparative genomics and convergent evolution analyses.We observed significant expansions and contractions in certain gene families across both high-altitude and marine mammals,closely associated with processes involved in pulmonary fibrosis.Notably,members of the keratin gene family,such as KRT17 and KRT14,appear to be associated with the development of the dense elastic fiber phenotype observed in the lungs of hypoxia-tolerant mammals.Through selection pressure and amino acid substitution analyses,we identified multiple genes exhibiting convergent accelerated evolution,positive selection,and amino acid substitution in these species,associated with adaptation to hypoxic environments.Specifically,the convergent evolution of ZFP36L1,FN1,and NEDD9 was found to contribute to the high density of elastic fibers in the lungs of both high-altitude and marine mammals,facilitating their hypoxia tolerance.Additionally,we identified convergent amino acid substitutions and gene loss events associated with sperm development,differentiation,and spermatogenesis,such as amino acid substitutions in SLC26A3 and pseudogenization of CFAP47,as confirmed by PCR.These genetic alterations may be linked to changes in the reproductive capabilities of these animals.Overall,this study offers novel perspectives on the genetic and molecular adaptations of high-altitude and marine mammals to hypoxic environments,with a particular emphasis on pulmonary fibrosis. 展开更多
关键词 Convergent evolution Pulmonary fibrosis high-altitude mammals Marine mammals HYPOXIA
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Clinical efficacy of intradermal type Ⅰ collagen injections in treating skin photoaging in patients from high-altitude areas
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作者 Bin Yang Ao He +6 位作者 Bin-Bin Bu Gong Zhuo Qing-Zhu Zhou Jia-Hang He Liu Liu Wen-Li Huang Xian Zhao 《World Journal of Clinical Cases》 SCIE 2024年第16期2713-2721,共9页
BACKGROUND Photoaging,a result of chronic sun exposure,leads to skin damage and pigmentation changes.Traditional treatments may have limitations in high-altitude areas like Yunnan Province.Intradermal Col Ⅰ injection... BACKGROUND Photoaging,a result of chronic sun exposure,leads to skin damage and pigmentation changes.Traditional treatments may have limitations in high-altitude areas like Yunnan Province.Intradermal Col Ⅰ injections stimulate collagen production,potentially improving skin quality.This study aims to assess the efficacy and safety of this treatment for photoaging.AIM To evaluate the efficacy and safety of intradermal typeΙcollagen(ColΙ)injection for treating photoaging.METHODS This prospective,self-controlled study investigated the impact of intradermal injections of ColΙon skin photodamage in 20 patients from the Yunnan Province.Total six treatment sessions were conducted every 4 wk±3 d.Before and after each treatment,facial skin characteristics were quantified using a VISIA skin detector.Skin thickness data were assessed using the ultrasound probes of the Dermalab skin detector.The Face-Q scale was used for subjective evaluation of the treatment effect by the patients.RESULTS The skin thickness of the right cheek consistently increased after each treatment session compared with baseline.The skin thickness of the left cheek significantly increased after the third through sixth treatment sessions compared with baseline.The skin thickness of the right zygomatic region increased after the second to sixth treatment sessions,whereas that of the left zygomatic region showed a significant increase after the fourth through sixth treatment sessions.The skin thickness of both temporal regions significantly increased after the fifth and sixth treatment sessions compared with baseline(P<0.05).These findings were also supported by skin ultrasound images.The feature count for the red areas and wrinkle feature count decreased following the treatment(P<0.05).VISIA assessments also revealed a decrease in the red areas after treatment.The Face-QSatisfaction with Facial Appearance Overall and Face-Q-Satisfaction with Skin scores significantly increased after each treatment session.The overall appearance of the patients improved after treatment.CONCLUSION Intradermal ColΙinjection improves photoaging,with higher patient satisfaction and fewer adverse reactions,and could be an effective treatment method for populations residing in high-altitude areas. 展开更多
关键词 PHOTOAGING TypeΙcollagen Face-Q high-altitude area Skin photodamage Patient satisfaction
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Atmospheric transmission algorithm for pulsed X-rays from high-altitude nuclear detonations based on scattering correction
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作者 Ding-Han Zhu Xiong Zhang +3 位作者 Xiao-Qiang Li Peng Li Yan-Bin Wang Shuang Zhang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第3期40-52,共13页
In high-altitude nuclear detonations,the proportion of pulsed X-ray energy can exceed 70%,making it a specific monitoring signal for such events.These pulsed X-rays can be captured using a satellite-borne X-ray detect... In high-altitude nuclear detonations,the proportion of pulsed X-ray energy can exceed 70%,making it a specific monitoring signal for such events.These pulsed X-rays can be captured using a satellite-borne X-ray detector following atmospheric transmission.To quantitatively analyze the effects of different satellite detection altitudes,burst heights,and transmission angles on the physical processes of X-ray transport and energy fluence,we developed an atmospheric transmission algorithm for pulsed X-rays from high-altitude nuclear detonations based on scattering correction.The proposed method is an improvement over the traditional analytical method that only computes direct-transmission X-rays.The traditional analytical method exhibits a maximum relative error of 67.79% compared with the Monte Carlo method.Our improved method reduces this error to within 10% under the same conditions,even reaching 1% in certain scenarios.Moreover,its computation time is 48,000 times faster than that of the Monte Carlo method.These results have important theoretical significance and engineering application value for designing satellite-borne nuclear detonation pulsed X-ray detectors,inverting nuclear detonation source terms,and assessing ionospheric effects. 展开更多
关键词 high-altitude nuclear detonation Atmospheric transmission Pulsed X-rays Scattering correction Analytical method Monte Carlo method
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Assessing foundation behaviour under complex loading near tunnels
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作者 Piyush KUMAR Vinay Bhushan CHAUHAN Aayush KUMAR 《Journal of Mountain Science》 SCIE CSCD 2024年第10期3503-3520,共18页
The stability of strip footings subjected to eccentrically inclined loads is critical for reliable foundation design.This study investigates the effect of a circular unlined tunnel in a rock mass on the ultimate beari... The stability of strip footings subjected to eccentrically inclined loads is critical for reliable foundation design.This study investigates the effect of a circular unlined tunnel in a rock mass on the ultimate bearing capacity(UBC)of a foundation with width B under inclined and eccentric loads.Adaptive finite element limit analysis was employed to evaluate the reduction in UBC of the footing resting above a tunnel.The examined critical parameters include normalized load eccentricity(e/B),load inclination(β),and horizontal and vertical distances of the tunnel from the foundation(P/B and Q/B,respectively),along with rock mass properties.The results reveal that for e/B≥0.25 and β≤60°,the reduction coefficient,R_(c)≥0.90,suggesting that the presence of a tunnel has a minimal impact on the load-bearing capacity of the footing,with failure primarily governed by load eccentricity and inclination.Additionally,potential failure mechanisms are explored,showing that at lower e/B,higher β,and lower Q/B,the tunnel significantly affects footing's failure envelope.Conversely,at higher e/B and lower β,failure is due to rotational effects of footing,regardless of the tunnel's position.To predict the Rc more accurately,due to the time-consuming nature of direct calculations,both MLR and ANN models were developed.The MLR model provided a baseline for comparison,while the ANN model,with a coefficient of determination(R2)of 0.98,demonstrated superior accuracy compared to the R2=0.96 of MLR.Using both approaches ensured robust and efficient predictions of Rc.Since Rc does not directly provide the reduced UBC of footing due to presence of tunnel,the study introduced bearing capacity factor(Nc)to enable direct calculation of the reduced UBC of footing.These findings offer theoretical guidelines for preliminary design and provide practitioners with an effective tool for evaluating UBC reduction in complex loading scenarios involving tunnels. 展开更多
关键词 Unlined tunnel Shallow foundation FELA Rock Mass ANN MLR
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Mechanical properties of steel mesh in anchor-mesh support for rocky tunnels
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作者 SUN Keguo JIA Jinglong +4 位作者 XU Weiping ZHANG Yu WANG Jinjin WANG Yichao LIU Yongkui 《Journal of Mountain Science》 SCIE CSCD 2024年第10期3487-3502,共16页
Underground geotechnical engineering encounters persistent challenges in ensuring the stability and safety of surrounding rock structures, particularly within rocky tunnels. Rock reinforcement techniques, including th... Underground geotechnical engineering encounters persistent challenges in ensuring the stability and safety of surrounding rock structures, particularly within rocky tunnels. Rock reinforcement techniques, including the use of steel mesh, are critical to achieving this goal. However, there exists a knowledge gap regarding the comprehensive understanding of the mechanical behavior and failure mechanisms exhibited by steel mesh under diverse loading conditions. This study thoroughly explored the steel mesh's performance throughout the entire loading-failure process, innovating with detailed analysis and modeling techniques. By integrating advanced numerical modeling with laboratory experiments, the study examines the influence of varying reinforcement levels and geometric parameters on the steel mesh strength and deformation characteristics. Sensitivity analysis, employing gray correlation theory, identifies the key factors affecting the mesh performance, while a BP (Backpropagation) neural network model predicts maximum vertical deformation with high accuracy. The findings underscore the critical role of steel diameter and mesh spacing in optimizing peak load capacity, displacement, and energy absorption, offering practical guidelines for design improvements. The use of a Bayesian Regularization (BR) algorithm further enhances the predictive accuracy compared to traditional methods. This research provides new insights into optimizing steel mesh design for underground applications, offering an innovative approach to enhancing structural safety in geotechnical projects. 展开更多
关键词 tunnel Steel mesh BP neural network Anchor-mesh support Rock reinforcement technique
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Roof collapse mechanism of weak surrounding rock for deep-buried tunnels under high geostress conditions
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作者 ZHANG Qi GUO Xiaokang +2 位作者 YAN Zhiguo LEI Zhongdai SHEN Yixin 《Journal of Mountain Science》 SCIE CSCD 2024年第7期2408-2426,共19页
High geostress,a typical attribute of tunnels located at significant depths,is crucial in causing stress-induced failure and influencing the stability of the tunnel crown.This study developed an analytical method for ... High geostress,a typical attribute of tunnels located at significant depths,is crucial in causing stress-induced failure and influencing the stability of the tunnel crown.This study developed an analytical method for the failure mechanism that occurs in deep-buried tunnel roofs,taking into account the influence of geostress.The limit analysis theory was utilized for deriving analytical solutions about the geometry of the collapsing surface and the limit supporting pressure.The collapsing surface obtained by the analytical solution was validated by the findings of the physical model test,which shows a high level of agreement with the actual one.An extensive investigation was done to explore the effects of the lateral pressure coefficients,the tunnel buried depth,the geological conditions of the surrounding rock,the long-short axis ratio,and the size of the tunnel profile.The findings indicate that an increase in the lateral pressure coefficient from 0.5 to 1.5 results in a reduction in the height of the collapsing zone by 2.08 m and the width of the collapsing zone by 1.15 m,while simultaneously increases the limit supporting pressure by 18.9%.The proposed upper bound method accurately determines the limit supporting pressure and the geometry of the collapsing surface,which aligns well with the results acquired through numerical modelling and on-site monitoring in actual engineering applications.The proposed analytical method can serve as a reference for similar crown failure issues of deep-buried tunnels. 展开更多
关键词 Geostress Deep-buried tunnels Collapse mechanism Pressure arch Limit analysis HoekBrown criterion
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A Simplified Method for the Stress Analysis of Underground Transfer Structures Crossing Multiple Subway Tunnels
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作者 Shen Yan Dajiang Geng +2 位作者 Ning Dai Mingjian Long Zhicheng Bai 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期2893-2915,共23页
According to the design specifications,the construction of extended piles involves traversing the tunnel’s upper region and extending to the underlying rock layer.To address this challenge,a subterranean transfer str... According to the design specifications,the construction of extended piles involves traversing the tunnel’s upper region and extending to the underlying rock layer.To address this challenge,a subterranean transfer structure spanning multiple subway tunnels was proposed.Deliberating on the function of piles in the transfer structure as springs with axial and bending stiffness,and taking into account the force balance and deformation coordination conditions of beams and plates within the transfer structure,we established a simplified mechanical model that incorporates soil stratification by combining it with the Winkler elastic foundation beam model.The resolved established simplifiedmechanicalmodel employed finite difference technology and the Newton-Simpsonmethod,elucidating the mechanical mechanism of the transfer structure.The research findings suggest that the load carried by the upper structural columns can be transferred to the pile foundation beneath the beams through the transfer structure,subsequently reaching the deep soil layer and ensuring minimal impact on adjacent tunnels.The established simplified analysis method can be used for stress analysis of the transfer structure,concurrently considering soil stratification,pile foundation behavior,and plate action.The pile length,pile section size,and beam section size within the transfer structure should account for the characteristics of the upper load,ensuring an even distribution of the beam bending moment. 展开更多
关键词 Crossing tunnels transfer structure force mechanism simplify analysis layered soil mass
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Mechanical responses of underground carriageway structures due to construction of metro tunnels beneath the existing structure:A case study
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作者 Xin Han Fei Ye +3 位作者 Xingbo Han Chao Ren Jing Song Ruliang Zhao 《Deep Underground Science and Engineering》 2024年第2期231-246,共16页
To understand the mechanical response pattern of the existing structure and ground due to the construction of metro tunnels underneath,the finite difference method is adopted to study the torsional deformation and str... To understand the mechanical response pattern of the existing structure and ground due to the construction of metro tunnels underneath,the finite difference method is adopted to study the torsional deformation and stress variation of the existing structure and the effect of underground carriageway structures on the surface subsidence.The curves of the maximum differential subsidence,torsion angle,and distortion of the cross-section of the existing structure show two peaks in succession during traversing of two metro tunnels beneath it.The torsion angle of the existing structure changes when the two tunnels traverse beneath it in opposite directions.The first traversing of the shield tunnel mainly induces the magnitude variation in torsional deformation of the existing structure,but the second traversing of the subsurface tunnel may cause a dynamic change in the magnitude and form of torsional deformation in the existing structure.The shielding effect can reduce the surface subsidence caused by metro tunnel excavation to a certain extent,and the development trend of subsidence becomes slower as the excavation continues. 展开更多
关键词 metro tunnel numerical simulation structural deformation surface subsidence underground carriageway structure
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Support design method for deep soft-rock tunnels in non-hydrostatic high in-situ stress field
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作者 ZHENG Ke-yue SHI Cheng-hua +3 位作者 ZHAO Qian-jin LEI Ming-feng JIA Chao-jun PENG Zhu 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第7期2431-2445,共15页
Due to the long-term plate tectonic movements in southwestern China,the in-situ stress field in deep formations is complex.When passing through deep soft-rock mass under non-hydrostatic high in-situ stress field,tunne... Due to the long-term plate tectonic movements in southwestern China,the in-situ stress field in deep formations is complex.When passing through deep soft-rock mass under non-hydrostatic high in-situ stress field,tunnels will suffer serious asymmetric deformation.There is no available support design method for tunnels under such a situation in existing studies to clarify the support time and support stiffness.This study first analyzed the mechanical behavior of tunnels in non-hydrostatic in-situ stress field and derived the theoretical equations of the ground squeezing curve(GSC)and ground loosening curve(GLC).Then,based on the convergence confinement theory,the support design method of deep soft-rock tunnels under non-hydrostatic high in-situ stress field was established considering both squeezing and loosening pressures.In addition,this method can provide the clear support time and support stiffness of the second layer of initial support.The proposed design method was applied to the Wanhe tunnel of the China-Laos railway in China.Monitoring data indicated that the optimal support scheme had a good effect on controlling the tunnel deformation in non-hydrostatic high in-situ stress field.Field applications showed that the secondary lining could be constructed properly. 展开更多
关键词 non-hydrostatic stress field high in-situ stress deep soft-rock tunnel squeezing pressure loosening pressure support design method
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Semi-analytical solution for mechanical analysis of tunnels crossing strike-slip fault zone considering nonuniform fault displacement and uncertain fault plane position
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作者 YANG Heng-hong WANG Ming-nian +1 位作者 YU Li ZHANG Xiao 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第6期2116-2136,共21页
The tunnel subjected to strike-slip fault dislocation exhibits severe and catastrophic damage.The existing analysis models frequently assume uniform fault displacement and fixed fault plane position.In contrast,post-e... The tunnel subjected to strike-slip fault dislocation exhibits severe and catastrophic damage.The existing analysis models frequently assume uniform fault displacement and fixed fault plane position.In contrast,post-earthquake observations indicate that the displacement near the fault zone is typically nonuniform,and the fault plane position is uncertain.In this study,we first established a series of improved governing equations to analyze the mechanical response of tunnels under strike-slip fault dislocation.The proposed methodology incorporated key factors such as nonuniform fault displacement and uncertain fault plane position into the governing equations,thereby significantly enhancing the applicability range and accuracy of the model.In contrast to previous analytical models,the maximum computational error has decreased from 57.1%to 1.1%.Subsequently,we conducted a rigorous validation of the proposed methodology by undertaking a comparative analysis with a 3D finite element numerical model,and the results from both approaches exhibited a high degree of qualitative and quantitative agreement with a maximum error of 9.9%.Finally,the proposed methodology was utilized to perform a parametric analysis to explore the effects of various parameters,such as fault displacement,fault zone width,fault zone strength,the ratio of maximum fault displacement of the hanging wall to the footwall,and fault plane position,on the response of tunnels subjected to strike-slip fault dislocation.The findings indicate a progressive increase in the peak internal forces of the tunnel with the rise in fault displacement and fault zone strength.Conversely,an augmentation in fault zone width is found to contribute to a decrease in the peak internal forces.For example,for a fault zone width of 10 m,the peak values of bending moment,shear force,and axial force are approximately 46.9%,102.4%,and 28.7% higher,respectively,compared to those observed for a fault zone width of 50 m.Furthermore,the position of the peak internal forces is influenced by variations in the ratio of maximum fault displacement of the hanging wall to footwall and the fault plane location,while the peak values of shear force and axial force always align with the fault plane.The maximum peak internal forces are observed when the footwall exclusively bears the entirety of the fault displacement,corresponding to a ratio of 0:1.The peak values of bending moment,shear force,and axial force for the ratio of 0:1 amount to approximately 123.8%,148.6%,and 111.1% of those for the ratio of 0.5:0.5,respectively. 展开更多
关键词 strike-slip fault tunnel engineering semi-analytical solution fault zone width nonuniform fault displacement uncertain fault plane position
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Dynamic performance assessment of shallow buried circular tunnels under explosion hazard
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作者 ZHANG Chen-long ZHANG Dong-ming +1 位作者 HUANG Zhong-kai HUANG Zhen 《Journal of Central South University》 CSCD 2024年第11期3868-3884,共17页
In recent years,the escalation in accidental explosions has emerged as a formidable threat to tunnel infrastructures.Therefore,it is of great significance to conduct a dynamic performance analysis of the tunnels,to im... In recent years,the escalation in accidental explosions has emerged as a formidable threat to tunnel infrastructures.Therefore,it is of great significance to conduct a dynamic performance analysis of the tunnels,to improve the safety and maintain the functionality of underground transport hubs.To this end,this study proposes a dynamic performance assessment framework to assess the extent of damage of shallow buried circular tunnels under explosion hazards.First,the nonlinear dynamic finite element numerical model of soil-tunnel interaction system under explosion hazard was established and validated.Then,based on the validated numerical model,an explosion intensity(EI)considering both explosion equivalent and relative distance was used to further analyze the dynamic response characteristics under typical explosion conditions.Finally,this study further explored the influence of the integrity and strength of the surrounding soil,concrete strength,lining thickness,rebar strength,and rebar rate on the tunnel dynamic performance.Our results show that the dynamic performance assessment framework proposed for shallow circular tunnels fully integrates the coupling effects of explosion equivalent and distance,and is able to accurately measure the degree of damage sustained by these structures under different EI.This work contributes to designing and managing tunnels and underground transport networks based on dynamic performance,thereby facilitating decision-making and efficient allocation of resources by consultants,operators,and stakeholders. 展开更多
关键词 tunnels explosion hazard dynamic performance assessment parametric analysis numerical study
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The role of polyurethane foam compressible layer in the mechanical behaviour of multi-layer yielding supports for deep soft rock tunnels
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作者 Haibo Wang Fuming Wang +3 位作者 Chengchao Guo Lei Qin Jun Liu Tongming Qu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第11期4554-4569,共16页
The polyurethane foam(PU)compressible layer is a viable solution to the problem of damage to the secondary lining in squeezing tunnels.Nevertheless,the mechanical behaviour of the multi-layer yielding supports has not... The polyurethane foam(PU)compressible layer is a viable solution to the problem of damage to the secondary lining in squeezing tunnels.Nevertheless,the mechanical behaviour of the multi-layer yielding supports has not been thoroughly investigated.To fill this gap,large-scale model tests were conducted in this study.The synergistic load-bearing mechanics were analyzed using the convergenceconfinement method.Two types of multi-layer yielding supports with different thicknesses(2.5 cm,3.75 cm and 5 cm)of PU compressible layers were investigated respectively.Digital image correlation(DIC)analysis and acoustic emission(AE)techniques were used for detecting the deformation fields and damage evolution of the multi-layer yielding supports in real-time.Results indicated that the loaddisplacement relationship of the multi-layer yielding supports could be divided into the crack initiation,crack propagation,strain-hardening,and failure stages.Compared with those of the stiff support,the toughness,deformability and ultimate load of the yielding supports were increased by an average of 225%,61%and 32%,respectively.Additionally,the PU compressible layer is positioned between two primary linings to allow the yielding support to have greater mechanical properties.The analysis of the synergistic bearing effect suggested that the thickness of PU compressible layer and its location significantly affect the mechanical properties of the yielding supports.The use of yielding supports with a compressible layer positioned between the primary and secondary linings is recommended to mitigate the effects of high geo-stress in squeezing tunnels. 展开更多
关键词 Multi-layer yielding supports Polyurethane foam compressible layer Synergistic mechanism Large-scale model test Deep soft rock tunnels
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Optimal intensity measures for longitudinal seismic response of tunnels
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作者 Zhao Xu Yang Yujie +2 位作者 Huang Jingqi Zhao Mi Cao Shengtao 《Journal of Southeast University(English Edition)》 EI CAS 2024年第4期346-354,共9页
To study the ground motion intensity measures(IMs)suitable for the design of seismic performance with a focus on longitudinal resistance in tunnel structures,21 different seismic intensity parameters are selected for ... To study the ground motion intensity measures(IMs)suitable for the design of seismic performance with a focus on longitudinal resistance in tunnel structures,21 different seismic intensity parameters are selected for nonlinear calculation and analysis of tunnel structures,in order to determine the optimal IM for the longitudinal seismic performance of tunnel structures under different site conditions.An improved nonlinear beam-spring model is developed to calculate the longitudinal seismic response of tunnels.The PQ-Fiber model is used to simulate the longitudinal nonlinear behavior of tunnel structures and the tangential interactions between the tunnel and the soil is realized by load in the form of moment.Five different site types are considered and 21 IMs is evaluated against four criteria:effectiveness,practicality,usefulness,and sufficiency.The results indicate that the optimal IMs are significantly influenced by the site conditions.Specifically,sustained maximum velocity(V_(SM))emerges as the optimal IM for circular tunnels in soft soil conditions(CaseⅠsites),peak ground velocity(V PG)is best suited for CaseⅡsites,sustained maximum acceleration(A_(SM))is ideal for both CaseⅢand CaseⅤsites,and peak ground acceleration(A PG)for CaseⅣsites.As site conditions transition from CaseⅠto CaseⅤ,from soft to hard,the applicability of acceleration-type intensity parameters gradually decreases,while the applicability of velocity-type intensity parameters gradually increases. 展开更多
关键词 seismic intensity measures tunnel longitudinal direction probabilistic seismic demand model soil-tunnel interaction improved ground-beam model
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Case study of performance assessment of overlapping shield tunnels with a small curve radius
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作者 Xu Zhang Bin Luo +2 位作者 Youjun Xu Chenxu Zhao Huachuan Wang 《Deep Underground Science and Engineering》 2024年第4期481-496,共16页
Due to the network planning of subways and their surrounding structures,increasingly more overlapping shields with a small curve radius have been constructed. A newly constructed upper tunnel partly overlaps a lower o... Due to the network planning of subways and their surrounding structures,increasingly more overlapping shields with a small curve radius have been constructed. A newly constructed upper tunnel partly overlaps a lower one, leading to the extremely complex uplift of the lower tunnel caused by the construction of a new tunnel. Based on the shield-driven project that runs from the Qinghe Xiaoyingqiao Station to the Qinghe Station in Beijing, which adopts the reinforcement measures of interlayer soil grouting and steel supports on site, in this study, the uplift pattern of the lower tunnel and the stress characteristics of steel supports were investigated through numerical simulations and on-site monitoring.The study results show that among all tunnel segments, the first segment of the shield witnesses a maximum uplift displacement that increases with the horizontal space between tunnels. On using either interlayer soil grouting or steel-ring bracing reinforcement, the uplift of the tunnel lining exceeds the control value;by contrast,when these two measures are jointly applied, the uplift of the tunnel lining does not exceed a maximum value of 4.87 mm, which can satisfy the requirements of deformation control. Under these two joint measures, the soil strength between two stacked shield tunnels can be enhanced and the uplift deformation can be restricted with the interlayer soil grouting. Also, the segmental deformation and overall stability of the existing tunnel can be controlled with the temporary steel supports.The deformation of circumferential supports and segments is closely related to each other, and the segmental uplift is controlled by H-shaped steel supports. With the increase in the horizontal space between twin shields, the effect of the construction would gradually weaken, accompanied by a gradual reduction of the stresses of steel supports. These findings provide a valuable reference for the engineering design and safe construction of overlapping shield tunnels with a small curve radius. 展开更多
关键词 field monitoring numerical simulation overlapping shields small curve radius steel support stress uplift of tunnel lining
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