BACKGROUND Intracranial high-density areas(HDAs)have attracted considerable attention for predicting clinical outcomes;however,whether HDAs predict worse neurological function and mental health remains controversial a...BACKGROUND Intracranial high-density areas(HDAs)have attracted considerable attention for predicting clinical outcomes;however,whether HDAs predict worse neurological function and mental health remains controversial and unclear,which requires further investigation.In this prospective study,96 patients with acute ischemic stroke(AIS)who accepted endovascular mechanical thrombectomy(EMT)were included.The enrolled patients underwent cranial computed tomography(CT)examination within 24 hours after EMT.Clinical data in terms of National Institutes of Health Stroke Scale(NIHSS),the 3-month modified Rankin Scale(mRS),self-rating depression scale(SDS),and self-rating anxiety scale(SAS)scores were collected and compared between patients with HDAs and non-HDAs and between patients with good and poor clinical prognosis.Compared to patients without HDAs,patients with HDAs presented severe neurological deficits(admission NIHSS score:18±3 vs 19±4),were more likely to have post-stroke disabilities(mRS<3:35%vs 62%),and suffered more severe depression(SDS score:58±16 vs 64±13)and anxiety disorder(SAS score:52±8 vs 59±10).Compared to patients with a good prognosis,patients with a poor prognosis presented severe neurological deficits(admission NIHSS score:17±4 vs 20±3),were more likely to have HDAs on CT images(64%vs 33%),and suffered more severe depression(SDS score:55±19 vs 65±11)and anxiety(SAS score:50±8 vs 58±12).Multivariate analysis revealed that HDAs were independent nega-tive prognostic factors.CONCLUSION In conclusion,HDAs on CT images predicted poor prognosis and severe depressive and anxiety symptoms in patients with AIS who underwent EMT.展开更多
During subway operation,various factors will cause long-term land subsidence,such as the vibration subsidence of foundation soil caused by train vibration load,incomplete consolidation deformation of foundation soil d...During subway operation,various factors will cause long-term land subsidence,such as the vibration subsidence of foundation soil caused by train vibration load,incomplete consolidation deformation of foundation soil during tunnel construction,dense buildings and structures in the vicinity of the tunnel,and changes in water level in the stratum where the tunnel is located.The monitoring of long-term land subsidence during subway operation in high-density urban areas differs from that in low-density urban construction areas.The former is the gathering point of the entire urban population.There are many complex buildings around the project,busy road traffic,high pedestrian flow,and less vegetation cover.Several existing items requiremonitoring.However,monitoring distance is long,and providing early warning is difficult.This study uses the 2.8 km operation line between Wulin Square station and Ding’an Road station of Hangzhou Subway Line 1 as an example to propose the integrated method of DInSAR-GPS-GIS technology and the key algorithm for long-term land subsidence deformation.Then,it selects multiscene image data to analyze long-termland subsidence of high-density urban areas during subway operation.Results show that long-term land subsidence caused by the operation of Wulin Square station to Ding’an Road station of Hangzhou Subway Line 1 is small,with maximumsubsidence of 30.64 mm,and minimumsubsidence of 11.45 mm,and average subsidence ranging from 19.27 to 21.33 mm.And FLAC3D software was used to verify the monitoring situation,using the geological conditions of the soil in the study area and the tunnel profile to simulate the settlement under vehicle load,and the simulation results tended to be consistent with the monitoring situation.展开更多
The Qilian Mountain permafrost area located in the northern of Qinghai-Tibet Plateau is a favorable place for natural gas hydrate formation and enrichment,due to its well-developed fractures and abundant gas sources.U...The Qilian Mountain permafrost area located in the northern of Qinghai-Tibet Plateau is a favorable place for natural gas hydrate formation and enrichment,due to its well-developed fractures and abundant gas sources.Understanding the formation and distribution of multi-component gas hydrates in fractures is crucial in accurately evaluating the hydrate reservoir resources in this area.The hydrate formation experiments were carried out using the core samples drilled from hydrate-bearing sediments in Qilian Mountain permafrost area and the multi-component gas with similar composition to natural gas hydrates in Qilian Mountain permafrost area.The formation and distribution characteristics of multi-component gas hydrates in core samples were observed in situ by X-ray Computed Tomography(X-CT)under high pressure and low temperature conditions.Results show that hydrates are mainly formed and distributed in the fractures with good connectivity.The ratios of volume of hydrates formed in fractures to the volume of fractures are about 96.8%and 60.67%in two different core samples.This indicates that the fracture surface may act as a favorable reaction site for hydrate formation in core samples.Based on the field geological data and the experimental results,it is preliminarily estimated that the inventory of methane stored in the fractured gas hydrate in Qilian Mountain permafrost area is about 8.67×1013 m3,with a resource abundance of 8.67×108 m3/km2.This study demonstrates the great resource potential of fractured gas hydrate and also provides a new way to further understand the prospect of natural gas hydrate and other oil and gas resources in Qilian Mountain permafrost area.展开更多
A helicon wave plasma source in a tube of ring permanent magnets(PMs)has been constructed to study the effect of the conflguration of the magnetic fleld with zero magnetic points on plasma parameters.This device also ...A helicon wave plasma source in a tube of ring permanent magnets(PMs)has been constructed to study the effect of the conflguration of the magnetic fleld with zero magnetic points on plasma parameters.This device also serves as an exploration platform for a simple,compact helicon wave plasma source adaptable to engineering applications.A small-diameter(26 mm)highdensity(~10^(18)m^(-3))blue core plasma is produced in~1 Pa argon by helicon RF(radiofrequency)discharge using a NagoyaⅢantenna under magnetic fleld(~2 k G)of compact ring PMs(length~204 mm).Operational parameters,i.e.RF power and neutral gas pressure are scanned and plasma density is measured by an RF compensated probe to explore the operating characteristics of the device.Iconic feature of a helicon discharge,such as blue core plasmas and E-H-W mode transitions are well observed in the device,despite the wavelength calculated using the conventional dispersion relation of a bounded whistler waves(Chen 1991 Plasma Phys.Control.Fusion 33339)is order of magnitudes longer than the length of the plasma in this device which seems to suggest that such helicon device is impossible.Surprisingly,the wavelength calculated by the unbounded whistle wave dispersion formula in turn suggests the occurrence of a half wavelength resonance.展开更多
The planning site was divided into a spatial structure of"one center,one corridor,two axes,two belts and three communities"and traffic system designed to a 3-grade road system of"artery,secondary artery...The planning site was divided into a spatial structure of"one center,one corridor,two axes,two belts and three communities"and traffic system designed to a 3-grade road system of"artery,secondary artery and by-pass".Meanwhile,a 3-ring structure of the planning site was constructed:diffusion waterfront landscape belt,waterfront pathway and core eco-green island.Finally,the planning concepts for major ecological constructions were given.This study tried to explore the group eco-landscape pattern in urban core areas so as to provide a strategic instruction for the regional sustainable development.展开更多
As an important element of urban renewal in highly urbanized areas, pocket parks with small size, flexible layout and daily accessibility are becoming a major component of green infrastructure and the mainstay of outd...As an important element of urban renewal in highly urbanized areas, pocket parks with small size, flexible layout and daily accessibility are becoming a major component of green infrastructure and the mainstay of outdoor recreation space expansion in high-density urban centers. Nevertheless, the absence of a comprehensive framework for evaluating the potential of pocket park construction (PPC), one that integrates diverse influencing factors on a macro scale, has resulted in the random installation of such spaces, often failing to optimize the utilization of urban land. Addressing this critical lacuna, we propose an approach to evaluate PPC potential from a city-scale perspective, which is used to support the determination of which land units should be prioritized for PPC. A complete and feasible workflow was also established to identify potential land units, construct an index system for PPC combining demand and supply levels, quantitatively calculate indices based on remote sensing (RS) and geographic information system (GIS), accurately evaluate PPC potential using an entropy-weighted TOPSIS model, and develop targeted renewal strategies. A case study in Dalian, China, demonstrated the applicability and implications of the workflow. The results showed that it is flexible and easy to adapt to different local contexts, allowing evaluators to introduce parameters considering the availability of local data, and will help decision makers to build pocket parks in the most effective plots, providing a strong reference for high-quality development in other high-density urban centers facing the contradiction between ecological construction and land scarcity.展开更多
Grain production core area is key region of modern agricultural development in China. Through summarizing related literature about grain production area and modern agricultural development researches both at home and ...Grain production core area is key region of modern agricultural development in China. Through summarizing related literature about grain production area and modern agricultural development researches both at home and abroad,it obtained characteristics and existing problems in the modern agricultural development of the grain production core area. It is found that there are many research perspectives in modern agricultural development of the grain production core area. On the basis of analyzing the grain production core area and connotation,mode and evaluation of the modern agricultural development,it is concluded that further study should be carried out for adopting which development mode and how to make evaluation,so as to provide theoretical guidance for balanced development of modern agriculture in grain production core area of different regions.展开更多
Objective:To study the changes of nitric oxide synthase(NOS)activity in penumbral and core area during focal cerebral ischemia and reperfusion,and to explore the therapeutic window of focal cerebral ischemia. Methods...Objective:To study the changes of nitric oxide synthase(NOS)activity in penumbral and core area during focal cerebral ischemia and reperfusion,and to explore the therapeutic window of focal cerebral ischemia. Methods:The middle cerebral artery of rats was occluded for 15,30,60,90 and 120 min by an intraluminal filament respectively,and recirculation was instituted for 24 h.The changes of NOS activity in ischemic core area(parietal cortex and caudoputamen)and penumbral area (frontal cortex)were examined after focal cerebral ischemia and reperfusion using NADPH-d histochemistry technique.Results:The NOS activity of the ischemic penumbral area peaked at 60 min while the ischemic core area peaked at 30 min then declined at 90-120 min sharply.Conclusion:NOS takes part in cerebral ischemic damage during focal cerebral ischemia and reperfusion.The NOS activity of the ischemic penumbral area is different from the ischemic core area.The peak time of the penumbral area is delayed comparing with the core area.The data suggest that the best time to apply NOS inhibitor is within 30 min in ischemic core area, and 60 min in penumbral area.展开更多
Studying tiie urban landscape pattern plays a crucial role in scientific land use and management and in improving the urban ecological environment In this paper, AutoCAD, ArcGIS, Fragstats, and other software were u...Studying tiie urban landscape pattern plays a crucial role in scientific land use and management and in improving the urban ecological environment In this paper, AutoCAD, ArcGIS, Fragstats, and other software were used to analyse the data of the fourth phase of land use in the core atea of Yangling Demonstration Zone. The results showed that: ① in the core area, the percentage of construction land incteased from 18.22% to 61.72%, and the percentage of agricultufal land decreased from 58.36% to 11.14%. And the fafm land was fragmented, and traffic connectivily was strengthened. The afea of garden land was reduced from 251.89 hm2 to 50.38 hm^2, and the landscape metric of forest land showed an inverted V-shaped curve. ②The year 2009 in four phases witnessed the greatest landscape fragmentation, both Edge Density (ED) and Ingest Patch Index (LPI) increased, and human interference enhanced the overall landscape complexity. Measures were fotmulated in terms of deaf development goals, optimized allocation of land resoutces, effective protection of ecological ted lines, and definite ecological responsibility, so as to optimize the urban landscape pattern.展开更多
Urban planning is a process of government as planner to purposefully manage and intervene in the urban development. In this paper,five major tasks for the construction of an international language environment in the c...Urban planning is a process of government as planner to purposefully manage and intervene in the urban development. In this paper,five major tasks for the construction of an international language environment in the core urban areas are proposed from the perspective of urban planning:to explore an effective working mechanism for the construction of the international language environment;to improve the ability of citizens in foreign language communication;to standardize public bilingual notices and signs marking system;to innovate the internationalized operational models of the key industries;to create a multi-functional foreign language consulting service system. Thereby,the objective to improve the international language environment and competitiveness of the urban areas can be accomplished.展开更多
The selected area electron diffraction (SAED) pattern of magnetic iron oxide core/gold shell nanoparticles has been studied. For the composite particles with mean size less than 10 nm, their SAED pattern is found to...The selected area electron diffraction (SAED) pattern of magnetic iron oxide core/gold shell nanoparticles has been studied. For the composite particles with mean size less than 10 nm, their SAED pattern is found to be different from either the pattern of pure Fe oxide nanoparticles or that of pure Au particles. Based on the fact that the ring diameters of these composite particles fit the characteristic relation for the fcc structure, the Au atoms on surfaces of the concerned particles are supposed to pack in a way more tightly than they usually do in pure Au nanoparticles. The driving force for this is the coherency strain which enables the shell material at the heterostructured interface to adapt the lattice parameters of the core.展开更多
文摘BACKGROUND Intracranial high-density areas(HDAs)have attracted considerable attention for predicting clinical outcomes;however,whether HDAs predict worse neurological function and mental health remains controversial and unclear,which requires further investigation.In this prospective study,96 patients with acute ischemic stroke(AIS)who accepted endovascular mechanical thrombectomy(EMT)were included.The enrolled patients underwent cranial computed tomography(CT)examination within 24 hours after EMT.Clinical data in terms of National Institutes of Health Stroke Scale(NIHSS),the 3-month modified Rankin Scale(mRS),self-rating depression scale(SDS),and self-rating anxiety scale(SAS)scores were collected and compared between patients with HDAs and non-HDAs and between patients with good and poor clinical prognosis.Compared to patients without HDAs,patients with HDAs presented severe neurological deficits(admission NIHSS score:18±3 vs 19±4),were more likely to have post-stroke disabilities(mRS<3:35%vs 62%),and suffered more severe depression(SDS score:58±16 vs 64±13)and anxiety disorder(SAS score:52±8 vs 59±10).Compared to patients with a good prognosis,patients with a poor prognosis presented severe neurological deficits(admission NIHSS score:17±4 vs 20±3),were more likely to have HDAs on CT images(64%vs 33%),and suffered more severe depression(SDS score:55±19 vs 65±11)and anxiety(SAS score:50±8 vs 58±12).Multivariate analysis revealed that HDAs were independent nega-tive prognostic factors.CONCLUSION In conclusion,HDAs on CT images predicted poor prognosis and severe depressive and anxiety symptoms in patients with AIS who underwent EMT.
基金financial supports for this research project by the National Natural Science Foundation of China(Nos.41602308,41967037)supported by Zhejiang Provincial Natural Science Foundation of China under Grant No.LY20E080005+1 种基金funded by National Key Research and Development Projects of China(No.2019YFC507502)Guangxi Science and Technology Plan Project(No.RZ2100000161).
文摘During subway operation,various factors will cause long-term land subsidence,such as the vibration subsidence of foundation soil caused by train vibration load,incomplete consolidation deformation of foundation soil during tunnel construction,dense buildings and structures in the vicinity of the tunnel,and changes in water level in the stratum where the tunnel is located.The monitoring of long-term land subsidence during subway operation in high-density urban areas differs from that in low-density urban construction areas.The former is the gathering point of the entire urban population.There are many complex buildings around the project,busy road traffic,high pedestrian flow,and less vegetation cover.Several existing items requiremonitoring.However,monitoring distance is long,and providing early warning is difficult.This study uses the 2.8 km operation line between Wulin Square station and Ding’an Road station of Hangzhou Subway Line 1 as an example to propose the integrated method of DInSAR-GPS-GIS technology and the key algorithm for long-term land subsidence deformation.Then,it selects multiscene image data to analyze long-termland subsidence of high-density urban areas during subway operation.Results show that long-term land subsidence caused by the operation of Wulin Square station to Ding’an Road station of Hangzhou Subway Line 1 is small,with maximumsubsidence of 30.64 mm,and minimumsubsidence of 11.45 mm,and average subsidence ranging from 19.27 to 21.33 mm.And FLAC3D software was used to verify the monitoring situation,using the geological conditions of the soil in the study area and the tunnel profile to simulate the settlement under vehicle load,and the simulation results tended to be consistent with the monitoring situation.
基金the financial support of the National Natural Science Foundation of China(42176212,41976074 and 41302034)the Marine S&T Fund of Shandong Province for Laoshan Laboratory(2021QNLM020002)the Marine Geological Survey Program(DD20221704)。
文摘The Qilian Mountain permafrost area located in the northern of Qinghai-Tibet Plateau is a favorable place for natural gas hydrate formation and enrichment,due to its well-developed fractures and abundant gas sources.Understanding the formation and distribution of multi-component gas hydrates in fractures is crucial in accurately evaluating the hydrate reservoir resources in this area.The hydrate formation experiments were carried out using the core samples drilled from hydrate-bearing sediments in Qilian Mountain permafrost area and the multi-component gas with similar composition to natural gas hydrates in Qilian Mountain permafrost area.The formation and distribution characteristics of multi-component gas hydrates in core samples were observed in situ by X-ray Computed Tomography(X-CT)under high pressure and low temperature conditions.Results show that hydrates are mainly formed and distributed in the fractures with good connectivity.The ratios of volume of hydrates formed in fractures to the volume of fractures are about 96.8%and 60.67%in two different core samples.This indicates that the fracture surface may act as a favorable reaction site for hydrate formation in core samples.Based on the field geological data and the experimental results,it is preliminarily estimated that the inventory of methane stored in the fractured gas hydrate in Qilian Mountain permafrost area is about 8.67×1013 m3,with a resource abundance of 8.67×108 m3/km2.This study demonstrates the great resource potential of fractured gas hydrate and also provides a new way to further understand the prospect of natural gas hydrate and other oil and gas resources in Qilian Mountain permafrost area.
基金supported by National Natural Science Foundation of China(No.U19A20113)。
文摘A helicon wave plasma source in a tube of ring permanent magnets(PMs)has been constructed to study the effect of the conflguration of the magnetic fleld with zero magnetic points on plasma parameters.This device also serves as an exploration platform for a simple,compact helicon wave plasma source adaptable to engineering applications.A small-diameter(26 mm)highdensity(~10^(18)m^(-3))blue core plasma is produced in~1 Pa argon by helicon RF(radiofrequency)discharge using a NagoyaⅢantenna under magnetic fleld(~2 k G)of compact ring PMs(length~204 mm).Operational parameters,i.e.RF power and neutral gas pressure are scanned and plasma density is measured by an RF compensated probe to explore the operating characteristics of the device.Iconic feature of a helicon discharge,such as blue core plasmas and E-H-W mode transitions are well observed in the device,despite the wavelength calculated using the conventional dispersion relation of a bounded whistler waves(Chen 1991 Plasma Phys.Control.Fusion 33339)is order of magnitudes longer than the length of the plasma in this device which seems to suggest that such helicon device is impossible.Surprisingly,the wavelength calculated by the unbounded whistle wave dispersion formula in turn suggests the occurrence of a half wavelength resonance.
文摘The planning site was divided into a spatial structure of"one center,one corridor,two axes,two belts and three communities"and traffic system designed to a 3-grade road system of"artery,secondary artery and by-pass".Meanwhile,a 3-ring structure of the planning site was constructed:diffusion waterfront landscape belt,waterfront pathway and core eco-green island.Finally,the planning concepts for major ecological constructions were given.This study tried to explore the group eco-landscape pattern in urban core areas so as to provide a strategic instruction for the regional sustainable development.
基金This study was supported by the National Natural Science Foundation of China(Grant No.52208045).
文摘As an important element of urban renewal in highly urbanized areas, pocket parks with small size, flexible layout and daily accessibility are becoming a major component of green infrastructure and the mainstay of outdoor recreation space expansion in high-density urban centers. Nevertheless, the absence of a comprehensive framework for evaluating the potential of pocket park construction (PPC), one that integrates diverse influencing factors on a macro scale, has resulted in the random installation of such spaces, often failing to optimize the utilization of urban land. Addressing this critical lacuna, we propose an approach to evaluate PPC potential from a city-scale perspective, which is used to support the determination of which land units should be prioritized for PPC. A complete and feasible workflow was also established to identify potential land units, construct an index system for PPC combining demand and supply levels, quantitatively calculate indices based on remote sensing (RS) and geographic information system (GIS), accurately evaluate PPC potential using an entropy-weighted TOPSIS model, and develop targeted renewal strategies. A case study in Dalian, China, demonstrated the applicability and implications of the workflow. The results showed that it is flexible and easy to adapt to different local contexts, allowing evaluators to introduce parameters considering the availability of local data, and will help decision makers to build pocket parks in the most effective plots, providing a strong reference for high-quality development in other high-density urban centers facing the contradiction between ecological construction and land scarcity.
文摘Grain production core area is key region of modern agricultural development in China. Through summarizing related literature about grain production area and modern agricultural development researches both at home and abroad,it obtained characteristics and existing problems in the modern agricultural development of the grain production core area. It is found that there are many research perspectives in modern agricultural development of the grain production core area. On the basis of analyzing the grain production core area and connotation,mode and evaluation of the modern agricultural development,it is concluded that further study should be carried out for adopting which development mode and how to make evaluation,so as to provide theoretical guidance for balanced development of modern agriculture in grain production core area of different regions.
文摘Objective:To study the changes of nitric oxide synthase(NOS)activity in penumbral and core area during focal cerebral ischemia and reperfusion,and to explore the therapeutic window of focal cerebral ischemia. Methods:The middle cerebral artery of rats was occluded for 15,30,60,90 and 120 min by an intraluminal filament respectively,and recirculation was instituted for 24 h.The changes of NOS activity in ischemic core area(parietal cortex and caudoputamen)and penumbral area (frontal cortex)were examined after focal cerebral ischemia and reperfusion using NADPH-d histochemistry technique.Results:The NOS activity of the ischemic penumbral area peaked at 60 min while the ischemic core area peaked at 30 min then declined at 90-120 min sharply.Conclusion:NOS takes part in cerebral ischemic damage during focal cerebral ischemia and reperfusion.The NOS activity of the ischemic penumbral area is different from the ischemic core area.The peak time of the penumbral area is delayed comparing with the core area.The data suggest that the best time to apply NOS inhibitor is within 30 min in ischemic core area, and 60 min in penumbral area.
基金Sponsored by Humanities and Social Sciences Project in Northwest A&F University(2015RWYB38)
文摘Studying tiie urban landscape pattern plays a crucial role in scientific land use and management and in improving the urban ecological environment In this paper, AutoCAD, ArcGIS, Fragstats, and other software were used to analyse the data of the fourth phase of land use in the core atea of Yangling Demonstration Zone. The results showed that: ① in the core area, the percentage of construction land incteased from 18.22% to 61.72%, and the percentage of agricultufal land decreased from 58.36% to 11.14%. And the fafm land was fragmented, and traffic connectivily was strengthened. The afea of garden land was reduced from 251.89 hm2 to 50.38 hm^2, and the landscape metric of forest land showed an inverted V-shaped curve. ②The year 2009 in four phases witnessed the greatest landscape fragmentation, both Edge Density (ED) and Ingest Patch Index (LPI) increased, and human interference enhanced the overall landscape complexity. Measures were fotmulated in terms of deaf development goals, optimized allocation of land resoutces, effective protection of ecological ted lines, and definite ecological responsibility, so as to optimize the urban landscape pattern.
基金The Philosophy and Social Science Planning Project of Henan Province(No.2013BYY013)the Key Humanities and Social Science Project of the Educational Department of Henan Province(No.2010-ZD 021)
文摘Urban planning is a process of government as planner to purposefully manage and intervene in the urban development. In this paper,five major tasks for the construction of an international language environment in the core urban areas are proposed from the perspective of urban planning:to explore an effective working mechanism for the construction of the international language environment;to improve the ability of citizens in foreign language communication;to standardize public bilingual notices and signs marking system;to innovate the internationalized operational models of the key industries;to create a multi-functional foreign language consulting service system. Thereby,the objective to improve the international language environment and competitiveness of the urban areas can be accomplished.
文摘The selected area electron diffraction (SAED) pattern of magnetic iron oxide core/gold shell nanoparticles has been studied. For the composite particles with mean size less than 10 nm, their SAED pattern is found to be different from either the pattern of pure Fe oxide nanoparticles or that of pure Au particles. Based on the fact that the ring diameters of these composite particles fit the characteristic relation for the fcc structure, the Au atoms on surfaces of the concerned particles are supposed to pack in a way more tightly than they usually do in pure Au nanoparticles. The driving force for this is the coherency strain which enables the shell material at the heterostructured interface to adapt the lattice parameters of the core.