Cold surges(CSs)often occur in the mid-latitude regions of the Northern Hemisphere and have enormous effects on socioeconomic development.We report that the occurrences of CSs and persistent CSs(PCSs)have rebounded si...Cold surges(CSs)often occur in the mid-latitude regions of the Northern Hemisphere and have enormous effects on socioeconomic development.We report that the occurrences of CSs and persistent CSs(PCSs)have rebounded since the 1990s,but the trends related to the frequencies of strong CSs(SCSs)and extreme CSs(ECSs)changed from increasing to decreasing after 2000.The highest-ranked model ensemble approach was used to project the occurrences of various CSs under the SSP1-2.6,SSP2-4.5,and SSP5-8.5 scenarios.The frequencies of the total CSs show overall decreasing trends.However,under the SSP1-2.6 scenario,slight increasing trends are noted for SCSs and ECSs in China.Atmospheric circulations that are characterized by an anomalous anticyclonic circulation with a significantly positive 500-hPa geopotential height(Z500)anomaly at high latitudes along with significant negative anomalies in China were favorable for cold air intrusions into China.In addition,the frequencies of all CS types under the SPP5-8.5 scenario greatly decreased in the long term(2071-2100),a finding which is thought to be related to negative SST anomalies in the central and western North Pacific,differences in sea level pressure(SLP)between high-and mid-latitude regions,and a weaker East Asian trough.In terms of ECSs,the decreasing trends observed during the historical period were maintained until 2024 under the SSP1-2.6 scenario.Compared to the SSP1-2.6 scenario,the Z500 pattern showed a trend of strengthened ridges over the Ural region and northern East Asia and weakened troughs over Siberia(60°-90°E)under the SSP2-4.5 and SSP5-8.5 scenarios,contributing to the shift to increasing trends of ECSs after 2014.展开更多
Climate change affects the activity of global and regional tropical cyclones(TCs).Among all TCs,typical super typhoons(STYs)are particularly devastating because they maintain their intensity when landing on the coast ...Climate change affects the activity of global and regional tropical cyclones(TCs).Among all TCs,typical super typhoons(STYs)are particularly devastating because they maintain their intensity when landing on the coast and thus cause casualties,economic losses,and environmental damage.Using a 3D tidal model,we reconstructed the typhoon(TY)wind field to simulate the storm surge induced by typical STYs.The TY activity was then analyzed using historical data.Results showed a downtrend of varying degrees in the annual frequency of STYs and TCs in the Western North Pacific(WNP)Basin,with a significant trend change observed for TCs from 1949 to 2021.A large difference in the interannual change in frequency was found between STYs and TCs in the WNP and Eastern China Sea(ECS).Along the coast of EC,the frequency of landfall TCs showed a weak downtrend,and the typical STYs showed reverse micro growth with peak activity in August.Zhejiang,Fujian,and Taiwan were highly vulnerable to the frontal hits of typical STYs.Affected by climate change,the average lifetime maximum intensity(LMI)locations and landfall locations of typical STYs in the ECS basin showed a significant poleward migration trend.In addition,the annual average LMI and accumulated cyclone energy showed an uptrend,indicating the increasing severity of the disaster risk.Affected by the typical STY activity in the ECS,the maximum storm surge area also showed poleward migration,and the coast of North China faced potential growth in high storm surge risks.展开更多
The gonadotropin-releasing hormone (GnRH) antagonist protocol has emerged as an efficacious alternative to the GnRH agonist protocol for controlled ovarian hyperstimulation (COH) during in vitro fertilization (IVF) cy...The gonadotropin-releasing hormone (GnRH) antagonist protocol has emerged as an efficacious alternative to the GnRH agonist protocol for controlled ovarian hyperstimulation (COH) during in vitro fertilization (IVF) cycles, and has been demonstrated applicability in infertile female patients with diverse ovarian responses. While the clinical implementation of the antagonist COH protocol has achieved widespread consensus, opportunities for refinement persist. Therefore, this review article focuses on the advantages and disadvantages of GnRH antagonist protocol, the selection of optimal standard doses, and the strategies for adjusting antagonist doses after the premature luteinizing hormone (LH) surge, aiming to provide more reasonable and scientific recommendations for the application of this scheme.展开更多
Storm surge is often the marine disaster that poses the greatest threat to life and property in coastal areas.Accurate and timely issuance of storm surge warnings to take appropriate countermeasures is an important me...Storm surge is often the marine disaster that poses the greatest threat to life and property in coastal areas.Accurate and timely issuance of storm surge warnings to take appropriate countermeasures is an important means to reduce storm surge-related losses.Storm surge numerical models are important for storm surge forecasting.To further improve the performance of the storm surge forecast models,we developed a numerical storm surge forecast model based on an unstructured spherical centroidal Voronoi tessellation(SCVT)grid.The model is based on shallow water equations in vector-invariant form,and is discretized by Arakawa C grid.The SCVT grid can not only better describe the coastline information but also avoid rigid transitions,and it has a better global consistency by generating high-resolution grids in the key areas through transition refinement.In addition,the simulation speed of the model is accelerated by using the openACC-based GPU acceleration technology to meet the timeliness requirements of operational ensemble forecast.It only takes 37 s to simulate a day in the coastal waters of China.The newly developed storm surge model was applied to simulate typhoon-induced storm surges in the coastal waters of China.The hindcast experiments on the selected representative typhoon-induced storm surge processes indicate that the model can reasonably simulate the distribution characteristics of storm surges.The simulated maximum storm surges and their occurrence times are consistent with the observed data at the representative tide gauge stations,and the mean absolute errors are 3.5 cm and 0.6 h respectively,showing high accuracy and application prospects.展开更多
The concept of a virtual human is rapidly fermenting with the boom of the metaverse in 2020.In March 2021,Roblox,a game company focusing on the socialization of teenagers’games and the free realization of UGC,went pu...The concept of a virtual human is rapidly fermenting with the boom of the metaverse in 2020.In March 2021,Roblox,a game company focusing on the socialization of teenagers’games and the free realization of UGC,went public.In its prospectus,Roblox is defined as the concept of the metaverse.Under this background,as the direct embodiment of“virtual identity”and“virtual reality coexisting”under the concept of the metaverse,the emerging definition of virtual human and its representative virtual image has gradually caught the attention of the public.展开更多
One of the viral terms on Chinese social media these days-“city bu city”–was actually created by a foreign tourist.The tourist,a blogger,used the term,which literally means city or not city,in a short video he film...One of the viral terms on Chinese social media these days-“city bu city”–was actually created by a foreign tourist.The tourist,a blogger,used the term,which literally means city or not city,in a short video he filmed while visiting the Great Wall,wondering whether the place is like a fashionable big city.展开更多
A method to improve the surge current capability of silicon carbide(SiC)merged PiN Schottky(MPS)diodes is presented and investigated via three-dimensional electro-thermal simulations.When compared with a conventional ...A method to improve the surge current capability of silicon carbide(SiC)merged PiN Schottky(MPS)diodes is presented and investigated via three-dimensional electro-thermal simulations.When compared with a conventional MPS diode,the proposed structure has a more uniform current distribution during bipolar conduction due to the help of the continuous P+surface,which can avoid the formation of local hotspots during the surge process.The Silvaco simulation results show that the proposed structure has a 20.29%higher surge capability and a 15.06%higher surge energy compared with a conventional MPS diode.The bipolar on-state voltage of the proposed structure is 4.69 V,which is 56.29%lower than that of a conventional MPS diode,enabling the device to enter the bipolar mode earlier during the surge process.Furthermore,the proposed structure can suppress the occurrence of‘snapback'phenomena when switching from the unipolar to the bipolar operation mode.In addition,an analysis of the surge process of MPS diodes is carried out in detail.展开更多
Coastal flooding caused by tropical cyclones has long been a major threat to life,property,and infrastructure in coastal zones.This study assessed the risk of flooding in Chittagong,southeastern Bangladesh,under extre...Coastal flooding caused by tropical cyclones has long been a major threat to life,property,and infrastructure in coastal zones.This study assessed the risk of flooding in Chittagong,southeastern Bangladesh,under extreme sea level scenarios caused by high astronomical tides and storm surges.The Jelesnianski typhoon model and the ADvanced CIRCulation hydrodynamic model were used to simulate 91 typhoons that occurred in the Bay of Bengal between 1981 and 2017,and observational data were used for model validation.The inundation model was based on a digital elevation model and a seed spread algorithm,and a geographical information system was used to visualize the flood risk.Under four scenarios,the changes in flood levels caused by sea level rise had no signifi-cant influence on the extent of flooding in Chittagong.At flood levels of 8.82m(50-year storm surge without sea level rise)and 8.89 m(50-year storm surge with sea level rise),the maximum estimated area of inundation was 11.35 km^(2).The western coastal and southeastern river coastal plain areas of Chittagong have the highest risk of inundation due to their low-lying terrain.At flood levels of 9.83m(100-year storm surge without sea level rise)and 9.97m(100-year storm surge with sea level rise),the maximum simulated flood extent was 36.44km^(2).Simulated floodwaters propagated in a south–north direction,and most of the northern areas of the city are at risk of inundation under these scenarios.展开更多
Compared with the traditional wind turbine of a single rotor,dual-rotor wind turbines(DRWTs)have higher wind energy capture efficiency and a more complex structure.Therefore,the aerodynamic performance of the DRWT ins...Compared with the traditional wind turbine of a single rotor,dual-rotor wind turbines(DRWTs)have higher wind energy capture efficiency and a more complex structure.Therefore,the aerodynamic performance of the DRWT installed on the floating platform will be greatly affected by the motion caused by wind and wave loads.In this paper,5 MW and 750 kW single rotor wind turbines(SRWTs)are combined into a 5 MW-5 MW DRWT and a 5 MW-750 kW DRWT,and their power output and wake field characteristics in different motions are studied.The flow field is obtained by solving the Reynolds-averaged Navier–Stokes equation(RANS).The overset grid technique is employed to achieve the large-amplitude multiple-degree-of-freedom motion of the DRWT.The overall performance of the 5 MW single rotor wind turbine is determined by a numerical method.For the DRWTs,numerical results show that the surge motion and heave motion both have a negative effect on the power output of the DRWT.The surge motion is a critical factor that causes the power output of the DRWT to periodically change with motion.The average power output of the DRWT influenced by motion is lower than that of a DRWT with a fixed bottom.The surge motion significantly disturbs the wake of the DRWT due to the mutual interference between the upstream and downstream rotors.Under the influence of heave motion,low-velocity regions downstream of the blade tip are enhanced.This study indicates that attenuating the surge and heave motion of offshore DRWT is very significant for improving its efficiency and should be taken into consideration during the design procedure.展开更多
Rich people in China are mainly gathered in the major and subordinate cities(the first,second & third tier cities).However,more than70% of the rich are outside of the major cities,with only 30% working and living ...Rich people in China are mainly gathered in the major and subordinate cities(the first,second & third tier cities).However,more than70% of the rich are outside of the major cities,with only 30% working and living in such展开更多
The South China Sea suffers strongly from the typhoon storm surge disasters in China,and its northern coastal areas are facing severe risks.Therefore,it is necessary and urgent to establish an assessment system for ra...The South China Sea suffers strongly from the typhoon storm surge disasters in China,and its northern coastal areas are facing severe risks.Therefore,it is necessary and urgent to establish an assessment system for rating typhoon storm surge disaster.We constructed an effective and reliable rating assessment system for typhoon storm surge disaster based on the theories of over-threshold,distribution function family,and composite extreme value.The over-threshold sample was used as the basis of data analysis,the composite extreme value expansion model was used to derive the design water increment,and then the disaster level was delineated based on the return period level.The results of the extreme value model comparison show that the Weibull-Pareto distribution is more suitable than the classical extreme value distribution for fitting the over-threshold samples.The results of the return period projection are relatively stable based on different analysis samples.Taking the 10 typhoon storm surges as examples,they caused landfall in the Guangdong area in the past 10 years.The results of the assessment ranking indicate that the risk levels based on the return period levels obtained from different distributions are generally consistent.When classifying low-risk areas,the classification criteria of the State Oceanic Administration,China(SOA,2012)are more conservative.In the high-risk areas,the results of the assessment ranking based on return period are more consistent with those of the SOA.展开更多
Objective:To analyze the curative effect of humidified high-flow nasal oxygen therapy combined with alveolar lavage in patients with severe pneumonia and respiratory failure.Methods:120 patients with severe pneumonia ...Objective:To analyze the curative effect of humidified high-flow nasal oxygen therapy combined with alveolar lavage in patients with severe pneumonia and respiratory failure.Methods:120 patients with severe pneumonia complicated with respiratory failure admitted to the Third People’s Hospital of Xining from July 2021 to December 2022 were randomly divided into two groups:group A and group B.The patients in group A were given humidified high-flow nasal oxygen therapy combined with alveolar lavage,whereas those in group B were given humidified high-flow nasal oxygen therapy.The treatment efficacy,blood gas analysis results,and differences in inflammatory mediators were compared between the two groups.Results:The curative effect in group A(96.67%)was significantly higher than that in group B(81.67%),P<0.05;the partial pressure of carbon dioxide(PaCO2),partial pressure of oxygen(PaO2),oxygen saturation(SpO2),and Horowitz index(P/F)of group A were significantly better than group B,P<0.05;the interleukin 6(IL-6),tumor necrosis factor alpha(TNF-α),and C-reactive protein(CRP)levels,white blood cell(WBC)count,serum procalcitonin(PCT),and neutrophil(N)percentage of group A were significantly lower than those of group B,P<0.05.Conclusion:For patients with severe pneumonia complicated with respiratory failure,alveolar lavage,on the basis of humidified high-flow oxygen therapy,can inhibit local inflammation,improve blood gas analysis results,promote disease recovery,and improve the clinical treatment effect。展开更多
基金supported by the National Key R&D Program of China(Grant No.2022YFF0801703)the State Key Laboratory of Earth Surface Processes and Resource Ecology(Grant No.2022-GS-01)in China.
文摘Cold surges(CSs)often occur in the mid-latitude regions of the Northern Hemisphere and have enormous effects on socioeconomic development.We report that the occurrences of CSs and persistent CSs(PCSs)have rebounded since the 1990s,but the trends related to the frequencies of strong CSs(SCSs)and extreme CSs(ECSs)changed from increasing to decreasing after 2000.The highest-ranked model ensemble approach was used to project the occurrences of various CSs under the SSP1-2.6,SSP2-4.5,and SSP5-8.5 scenarios.The frequencies of the total CSs show overall decreasing trends.However,under the SSP1-2.6 scenario,slight increasing trends are noted for SCSs and ECSs in China.Atmospheric circulations that are characterized by an anomalous anticyclonic circulation with a significantly positive 500-hPa geopotential height(Z500)anomaly at high latitudes along with significant negative anomalies in China were favorable for cold air intrusions into China.In addition,the frequencies of all CS types under the SPP5-8.5 scenario greatly decreased in the long term(2071-2100),a finding which is thought to be related to negative SST anomalies in the central and western North Pacific,differences in sea level pressure(SLP)between high-and mid-latitude regions,and a weaker East Asian trough.In terms of ECSs,the decreasing trends observed during the historical period were maintained until 2024 under the SSP1-2.6 scenario.Compared to the SSP1-2.6 scenario,the Z500 pattern showed a trend of strengthened ridges over the Ural region and northern East Asia and weakened troughs over Siberia(60°-90°E)under the SSP2-4.5 and SSP5-8.5 scenarios,contributing to the shift to increasing trends of ECSs after 2014.
基金supported by four funds,including the National Key Research and Development Program of China(No.2022YFC3106102)the Marine Science and Technology Innovation Project of Jiangsu Province(Nos.JSZRH YKJ202105,JSZRHYKI202303)+1 种基金the Nantong Social and Livelihood Science and Technology Project(Nos.MS12022009,MS22022082,MS22022083)the Project on Excellent Post-Graduate Dissertation of Hohai University(No.422003470).
文摘Climate change affects the activity of global and regional tropical cyclones(TCs).Among all TCs,typical super typhoons(STYs)are particularly devastating because they maintain their intensity when landing on the coast and thus cause casualties,economic losses,and environmental damage.Using a 3D tidal model,we reconstructed the typhoon(TY)wind field to simulate the storm surge induced by typical STYs.The TY activity was then analyzed using historical data.Results showed a downtrend of varying degrees in the annual frequency of STYs and TCs in the Western North Pacific(WNP)Basin,with a significant trend change observed for TCs from 1949 to 2021.A large difference in the interannual change in frequency was found between STYs and TCs in the WNP and Eastern China Sea(ECS).Along the coast of EC,the frequency of landfall TCs showed a weak downtrend,and the typical STYs showed reverse micro growth with peak activity in August.Zhejiang,Fujian,and Taiwan were highly vulnerable to the frontal hits of typical STYs.Affected by climate change,the average lifetime maximum intensity(LMI)locations and landfall locations of typical STYs in the ECS basin showed a significant poleward migration trend.In addition,the annual average LMI and accumulated cyclone energy showed an uptrend,indicating the increasing severity of the disaster risk.Affected by the typical STY activity in the ECS,the maximum storm surge area also showed poleward migration,and the coast of North China faced potential growth in high storm surge risks.
基金Hainan Province Major Science and Technology Plan Projects(No.ZDKJ2021037,ZDKJ2017007)National Natural Science Foundation of China(No.81960283),and Co-funded by the Hainan Provincial Academician Innovation Platform Research Project and the Hainan Provincial Clinical Medicine Center Construction Project。
文摘The gonadotropin-releasing hormone (GnRH) antagonist protocol has emerged as an efficacious alternative to the GnRH agonist protocol for controlled ovarian hyperstimulation (COH) during in vitro fertilization (IVF) cycles, and has been demonstrated applicability in infertile female patients with diverse ovarian responses. While the clinical implementation of the antagonist COH protocol has achieved widespread consensus, opportunities for refinement persist. Therefore, this review article focuses on the advantages and disadvantages of GnRH antagonist protocol, the selection of optimal standard doses, and the strategies for adjusting antagonist doses after the premature luteinizing hormone (LH) surge, aiming to provide more reasonable and scientific recommendations for the application of this scheme.
基金The National Natural Science Foundation of China under contract No.42076214.
文摘Storm surge is often the marine disaster that poses the greatest threat to life and property in coastal areas.Accurate and timely issuance of storm surge warnings to take appropriate countermeasures is an important means to reduce storm surge-related losses.Storm surge numerical models are important for storm surge forecasting.To further improve the performance of the storm surge forecast models,we developed a numerical storm surge forecast model based on an unstructured spherical centroidal Voronoi tessellation(SCVT)grid.The model is based on shallow water equations in vector-invariant form,and is discretized by Arakawa C grid.The SCVT grid can not only better describe the coastline information but also avoid rigid transitions,and it has a better global consistency by generating high-resolution grids in the key areas through transition refinement.In addition,the simulation speed of the model is accelerated by using the openACC-based GPU acceleration technology to meet the timeliness requirements of operational ensemble forecast.It only takes 37 s to simulate a day in the coastal waters of China.The newly developed storm surge model was applied to simulate typhoon-induced storm surges in the coastal waters of China.The hindcast experiments on the selected representative typhoon-induced storm surge processes indicate that the model can reasonably simulate the distribution characteristics of storm surges.The simulated maximum storm surges and their occurrence times are consistent with the observed data at the representative tide gauge stations,and the mean absolute errors are 3.5 cm and 0.6 h respectively,showing high accuracy and application prospects.
文摘The concept of a virtual human is rapidly fermenting with the boom of the metaverse in 2020.In March 2021,Roblox,a game company focusing on the socialization of teenagers’games and the free realization of UGC,went public.In its prospectus,Roblox is defined as the concept of the metaverse.Under this background,as the direct embodiment of“virtual identity”and“virtual reality coexisting”under the concept of the metaverse,the emerging definition of virtual human and its representative virtual image has gradually caught the attention of the public.
文摘One of the viral terms on Chinese social media these days-“city bu city”–was actually created by a foreign tourist.The tourist,a blogger,used the term,which literally means city or not city,in a short video he filmed while visiting the Great Wall,wondering whether the place is like a fashionable big city.
基金the National Research and Development Program for Major Research Instruments of China(Grant No.62027814)the National Natural Science Foundation of China(Grant No.61904045)Zhejiang Provincial Natural Science Foundation of China(Grant No.LQ20F040004)。
文摘A method to improve the surge current capability of silicon carbide(SiC)merged PiN Schottky(MPS)diodes is presented and investigated via three-dimensional electro-thermal simulations.When compared with a conventional MPS diode,the proposed structure has a more uniform current distribution during bipolar conduction due to the help of the continuous P+surface,which can avoid the formation of local hotspots during the surge process.The Silvaco simulation results show that the proposed structure has a 20.29%higher surge capability and a 15.06%higher surge energy compared with a conventional MPS diode.The bipolar on-state voltage of the proposed structure is 4.69 V,which is 56.29%lower than that of a conventional MPS diode,enabling the device to enter the bipolar mode earlier during the surge process.Furthermore,the proposed structure can suppress the occurrence of‘snapback'phenomena when switching from the unipolar to the bipolar operation mode.In addition,an analysis of the surge process of MPS diodes is carried out in detail.
基金funded by the National Key Research and Development Program of China(No.2016YFC1401103)Funds for the Central Universities(No.202165003)the Open Fund of Shandong Province Key Laboratory of Ocean Engineering,Ocean University of China(No.kloe201903).
文摘Coastal flooding caused by tropical cyclones has long been a major threat to life,property,and infrastructure in coastal zones.This study assessed the risk of flooding in Chittagong,southeastern Bangladesh,under extreme sea level scenarios caused by high astronomical tides and storm surges.The Jelesnianski typhoon model and the ADvanced CIRCulation hydrodynamic model were used to simulate 91 typhoons that occurred in the Bay of Bengal between 1981 and 2017,and observational data were used for model validation.The inundation model was based on a digital elevation model and a seed spread algorithm,and a geographical information system was used to visualize the flood risk.Under four scenarios,the changes in flood levels caused by sea level rise had no signifi-cant influence on the extent of flooding in Chittagong.At flood levels of 8.82m(50-year storm surge without sea level rise)and 8.89 m(50-year storm surge with sea level rise),the maximum estimated area of inundation was 11.35 km^(2).The western coastal and southeastern river coastal plain areas of Chittagong have the highest risk of inundation due to their low-lying terrain.At flood levels of 9.83m(100-year storm surge without sea level rise)and 9.97m(100-year storm surge with sea level rise),the maximum simulated flood extent was 36.44km^(2).Simulated floodwaters propagated in a south–north direction,and most of the northern areas of the city are at risk of inundation under these scenarios.
基金financially supported by the Guangdong Basic and Applied Basic Research Foundation,China (Grant Nos.2021A1515011771 and 2022B1515250005)the National Natural Science Foundation of China (Grant Nos.52171289,52201350,and 52201394)+1 种基金the National Key Research and Development Program of China (Grant No.2022YFC28063)the Innovation Group Project of Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) (Grant No.SML 2022016)。
文摘Compared with the traditional wind turbine of a single rotor,dual-rotor wind turbines(DRWTs)have higher wind energy capture efficiency and a more complex structure.Therefore,the aerodynamic performance of the DRWT installed on the floating platform will be greatly affected by the motion caused by wind and wave loads.In this paper,5 MW and 750 kW single rotor wind turbines(SRWTs)are combined into a 5 MW-5 MW DRWT and a 5 MW-750 kW DRWT,and their power output and wake field characteristics in different motions are studied.The flow field is obtained by solving the Reynolds-averaged Navier–Stokes equation(RANS).The overset grid technique is employed to achieve the large-amplitude multiple-degree-of-freedom motion of the DRWT.The overall performance of the 5 MW single rotor wind turbine is determined by a numerical method.For the DRWTs,numerical results show that the surge motion and heave motion both have a negative effect on the power output of the DRWT.The surge motion is a critical factor that causes the power output of the DRWT to periodically change with motion.The average power output of the DRWT influenced by motion is lower than that of a DRWT with a fixed bottom.The surge motion significantly disturbs the wake of the DRWT due to the mutual interference between the upstream and downstream rotors.Under the influence of heave motion,low-velocity regions downstream of the blade tip are enhanced.This study indicates that attenuating the surge and heave motion of offshore DRWT is very significant for improving its efficiency and should be taken into consideration during the design procedure.
文摘Rich people in China are mainly gathered in the major and subordinate cities(the first,second & third tier cities).However,more than70% of the rich are outside of the major cities,with only 30% working and living in such
基金Supported by the National Natural Science Foundation of China(Nos.52071306,52101360)the Natural Science Foundation of Shandong Province(No.ZR2019MEE050)the State Key Laboratory of Coastal and Offshore Engineering(No.LP2104)。
文摘The South China Sea suffers strongly from the typhoon storm surge disasters in China,and its northern coastal areas are facing severe risks.Therefore,it is necessary and urgent to establish an assessment system for rating typhoon storm surge disaster.We constructed an effective and reliable rating assessment system for typhoon storm surge disaster based on the theories of over-threshold,distribution function family,and composite extreme value.The over-threshold sample was used as the basis of data analysis,the composite extreme value expansion model was used to derive the design water increment,and then the disaster level was delineated based on the return period level.The results of the extreme value model comparison show that the Weibull-Pareto distribution is more suitable than the classical extreme value distribution for fitting the over-threshold samples.The results of the return period projection are relatively stable based on different analysis samples.Taking the 10 typhoon storm surges as examples,they caused landfall in the Guangdong area in the past 10 years.The results of the assessment ranking indicate that the risk levels based on the return period levels obtained from different distributions are generally consistent.When classifying low-risk areas,the classification criteria of the State Oceanic Administration,China(SOA,2012)are more conservative.In the high-risk areas,the results of the assessment ranking based on return period are more consistent with those of the SOA.
文摘Objective:To analyze the curative effect of humidified high-flow nasal oxygen therapy combined with alveolar lavage in patients with severe pneumonia and respiratory failure.Methods:120 patients with severe pneumonia complicated with respiratory failure admitted to the Third People’s Hospital of Xining from July 2021 to December 2022 were randomly divided into two groups:group A and group B.The patients in group A were given humidified high-flow nasal oxygen therapy combined with alveolar lavage,whereas those in group B were given humidified high-flow nasal oxygen therapy.The treatment efficacy,blood gas analysis results,and differences in inflammatory mediators were compared between the two groups.Results:The curative effect in group A(96.67%)was significantly higher than that in group B(81.67%),P<0.05;the partial pressure of carbon dioxide(PaCO2),partial pressure of oxygen(PaO2),oxygen saturation(SpO2),and Horowitz index(P/F)of group A were significantly better than group B,P<0.05;the interleukin 6(IL-6),tumor necrosis factor alpha(TNF-α),and C-reactive protein(CRP)levels,white blood cell(WBC)count,serum procalcitonin(PCT),and neutrophil(N)percentage of group A were significantly lower than those of group B,P<0.05.Conclusion:For patients with severe pneumonia complicated with respiratory failure,alveolar lavage,on the basis of humidified high-flow oxygen therapy,can inhibit local inflammation,improve blood gas analysis results,promote disease recovery,and improve the clinical treatment effect。