Experimental and clinical study of influence of high-frequency electric surgical knives on healing of abdominal incision

AIM： To study the influence of high-frequency electric surgical knives on healing of abdominal incision. METHODS： Two hundred and forty white rats were divided into 10^0, 10^2, 10^5, and 10^8 groups and rat models of abdominal operation were induced by using electric surgical knives and common lancets respectively. Then they were respectively given hypodermic injections of normal saline and 0.2 mL quantitative mixture of Escherichia coil, Staphylococcus aureus and Pseudornonas aeruginosa at a concentration of 10^2, 10^5 and 10^8. On the basis of the animal experiment, 220 patients undergoing abdominal operations （above type Ⅱ） were randomly allocated into one of following three groups： electric knife （EK, 93 cases）, electro-coagulation （EC, 55 cases） and control （72 cases）. High-frequency electric surgical knives were used to dissect abdominal tissues and electro-coagulation for hemostasis in EK group. Common lancets and electro-coagulation were applied in EC group. Common lancets and tieing silk suture were used in the controls. RESULTS： In all the groups except group 10^0, infection rate of incisional wounds made by electric surgical knives were remarkably higher than that with common lancets. Furthermore, there were significant differences in groups 10^2, 10^5, and 10^8 （P 〈 0.05）, but not in group 10^0 （P 〉 0.05） between EK and EC groups. Clinical studies showed a delayed wound healing in 16 cases （17.20%） in EK, 11 cases （16.36%） in EC and 2 cases （2.86%）in the control groups. A significant difference between EK and the control groups （χ^2= 8.57, P 〈 0.01）, and between EC and the control groups （χ^2 = 5.66, P 〈 0.05） was observed, but not between EK and EC （χ^2= 0.017, P 〉 0.05）. CONCLUSION： High-frequency electric knives may remarkably delay abdominal incision healing. Its application should be minimized so as to reduce the possibility of postoperative complications.

High-frequency spinal cord stimulation produces longlasting analgesic effects by restoring lysosomal function and autophagic flux in the spinal dorsal horn

High-frequency spinal cord stimulation(HF-SCS) has been established as an effective therapy for neuropathic pain. However, the analgesic mechanisms involved in HF-SCS remain to be clarified. In our study, adult rat neuropathic pain was induced by spinal nerve ligation. Two days after modeling, the rats were subjected to 4 hours of HF-SCS(motor threshold 50%, frequency 10,000 Hz, and pulse width 0.024 ms) in the dorsal horn of the spinal cord. The results revealed that the tactile allodynia of spinal nerve-injured rats was markedly alleviated by HFSCS, and the effects were sustained for 3 hours after the stimulation had ceased. HF-SCS restored lysosomal function, increased the levels of lysosome-associated membrane protein 2(LAMP2) and the mature form of cathepsin D(matu-CTSD), and alleviated the abnormally elevated levels of microtubule-associated protein 1 A/B-light chain 3(LC3)-II and sequestosome 1(P62) in spinal nerve-injured rats. HF-SCS also mostly restored the immunoreactivity of LAMP2, which was localized in neurons in the superficial layers of the spinal dorsal horn in spinal nerve-injured rats. In addition, intraperitoneal administration of 15 mg/kg chloroquine for 60 minutes reversed the expression of the aforementioned proteins and shortened the timing of the analgesic effects of HF-SCS. These findings suggest that HF-SCS may exhibit longlasting analgesic effects on neuropathic pain in rats through improving lysosomal dysfunction and alleviating autophagic flux. This study was approved by the Laboratory Animal Ethics Committee of China Medical University, Shenyang, China(approval No. 2017 PS196 K) on March 1, 2017.

The electrical parameters measurement system for electrotome output based on Labview

An accurate detection of the effective values of electric voltage and current from high frequency power generators is a precondition for the development of smart electrotomes. In this light, an energy detection system based on personal computer (PC) is developed hereby. It senses voltage and current in isolation from generators with transformers, and then the measured values are amplified, filtered, transformed into single-ended signals and converted to RMS. The detected signals are transformed into digital signals through Data Acquisition Card (DAQ) and the data are processed with quadratic fit in Labview. Finally, the controller completes constant power output. The experiment results indicate that the energy detection system can measure the output parameters precisely and the controller can achieve constant power control.

Hippocampal High-Frequency Stimulation Inhibites the Progression of Rapid Kindling-Induced Seizure in Rats

Epilepsy is one of the most common serious neurological disorders. Pharmacoresistant epilepsy patients are poorly controlled or their seizures are refractory to drug treatment. Resective surgery is frequently a promising therapy in this population, however, not all the patients meet the eligibility criteria for the surgical treatment. Deep brain stimulation has been investigated in clinical studies and animal studies as an alternative treatment, but the optimal stimulation parameters remain an issue. The present study was designed to investigate the effect of unilateral high-frequency stimulation (HFS) of hippocampus on seizure development by using the hippocampal rapid kindling method (hRK) in rats, and compared the results with those of low-frequency stimulation previously published by our group. We used male Wistar rats implanted with electrodes in the ventral hippocampus. All rats underwent hRK (biphasic square wave pulses, 20 Hz for 10 seconds) during three consecutive days (twelve stimulations per day). The control group (hRK;n = 7) received only RK stimulus, while the treated group (HFS-hRK;n = 9) received also HFS (biphasic square wave pulses, 130 Hz for 30 seconds) immediately before the RK stimulus, during three consecutive days. At the end of behavioral testing 78% (p 0.01) of the animals receiving HFS treatment were still not fully kindled staying in stages 0 -III (p 0.01). HFS group needed a higher number of stimulations to achieve stage III (p 0.05) with respect to control group. However, no significant differences in the cumulative daily afterdischarge duration were observed. HFS did not present significant differences compared with LFS in any of studied parameters. The findings suggest that unilateral HFS applied on hippocampus effectively inhibited the epileptogenic process induced by hippocampal rapid kindling. According to the comparative results about hippocampal rapid kindled animals stimulated with HFS and LFS (5 Hz), we found no conclusive information on which treatment is most efficient.

A portable,auxiliary photovoltaic power system for electric vehicles based on a foldable scissors mechanism

In recent years,countries worldwide have actively advocated electric vehicles for environmental protection.How-ever,restrictions on the driving range and charging have hampered the promotion of electric vehicles.This study proposes a portable,auxiliary photovoltaic power system based on a foldable scissors mechanism for electric vehicles.The system includes a photovoltaic power generation module and an electricity transfer module.The photovoltaic power generation module built based on a foldable scissors mechanism is five times smaller than in its unfolded state,improving its portability in its folded state.The electricity transfer module transfers electricity into the cabin via wireless power transfer units and stores electricity in supercapacitors.Solar simulation exper-iments were conducted to evaluate the system’s performance:maximum output power of 1.736 W is measured when the load is 5Ω,while maximum wireless power transfer efficiency is up to 57.7% with 10Ω load.An elec-tric vehicle in Chengdu city was simulated for a case study.The results show that the annual output of a single photovoltaic power system can drive the MINIEV for 423.625 km,indicating that the proposed system would be able to supply power for electric vehicles as an auxiliary power supply system.

Observations on Curative Effect of High-frequency Electric Sparkle and Point-injection Therapy on Knee Osteoarthritis

Objective: To observe the curative effect of high-frequency electric sparkle and point-injection therapy (HESPT) on knee osteoarthritis (KOA). Methods: Two hundred and five patients were randomly divided into a warming needle moxibustion group (68 cases), a HESPT group (68 cases) and a point-injection group (69 cases). In the warming needle moxibustion group, the main points of Xuehai (SP 10), Neixiyan (EX-LE4), Waixiyan (EX-LE5), Dubi (ST 35), Zusanli (ST 36) and Yanglingquan (GB 34), and the adjunct points of Yinlingquan (SP 9) and Sanyinjiao (SP 6), on the affected side, were chosen for stimulation. In the HESPT group, tenderness points, the main points of Liangqiu (ST 34), Xuehai (SP 10), Neixiyan (EX-LE4), Waixiyan (EX-LE5) and Zusanli (ST 36), and the adjunct points of Yinlingquan (SP 9), Weizhong (BL 40) and Chengshan (BL 57), were chosen. After proper manipulation, Corydalis decumbens Pers. liquid was injected into the points and a high-frequency electric sparkle was applied to stimulate the needles for 30 seconds. In the point-injection group, point injection was performed with the same method, but the patients did not receive electric stimulation. The Western Ontario and McMaster University Osteoarthritis Index (WOMAC), the Lysholm Knee Score Scale (LKSS) and the ROM (Range of Motion) scale were used to evaluate the severity of KOA and the function of knee joints before treatment and 4 weeks after treatment. Finally, the Nimodipine method was used to assess the total curative effect. Results: After HESPT treatment, the scores for pain, morning stiffness and swelling were significantly lower (P<0.01) and LKSS index and ROM were much higher (P<0.01 and P<0.05 respectively) compared to the two other groups. The obviously effective rate and total effective rate were also significantly higher in the HESPT group than in the two other groups (P<0.01 or P<0.05). Conclusion: HESPT can improve joint function in KOA patients, and the curative effect is better than for warming needle moxibustion or point-injection only.

基于仿生微织构的电动修剪机刀具磨损性能研究

针对普通电动修剪机刀具易磨损、崩刃等情况,设计了一种蚯蚓仿生微织构刀具,以蚯蚓体表形貌为基础,利用激光成型技术加工刀具表面微织构,研究激光成型参数对成型沟槽几何尺寸的影响;通过摩擦磨损对比试验研究了仿生微织构刀具和普通刀具的摩擦因数和磨损情况,分析仿生刀具减磨机理;通过自制剪切试验平台对不同直径龙眼树枝进行刀具剪切试验,验证仿生刀具减磨特性。研究结果表明:优化后激光成型仿生刀具的工艺参数为:激光功率75 W、激光扫描速度4.8 mm/s;仿生刀具微织构实际尺寸为:沟宽138.3μm,沟深33.5μm;与普通刀具相比,载荷400 g下沟槽间距1.6 mm时微织构仿生刀具表现出最小摩擦因数0.2619和体积磨损量616.70 mm^3,具有明显减磨特性;随载荷增加磨损机制逐渐由黏着磨损、微切削磨损向磨粒磨损和氧化磨损的复杂磨损形式转变;磨损稳定时,沟槽间距1.6 mm微织构仿生刀具所需剪切次数50~55次,比普通刀具剪切次数(45~50次)高5~10次,沟槽间距1.6 mm微织构仿生刀具在剪切直径10、15、20 mm的树枝磨损面积稳定次数分别为35~40次、45~50次、50~55次,树枝直径越大微织构刀具抗磨效果越明显。

宫腔粘连分离术中应用微型剪的效果评估

目的:比较微型剪和电切环在有生育要求的中重度宫腔粘连患者手术中的应用效果差异。方法:选择2014年9月至2016年12月至浙江省人民医院生殖内分泌科因中重度宫腔粘连拟行宫腔镜下粘连分离术的女性患者82例,分为微型剪分离组(n=39)和电切环分离组(n=43)。在手术当月的月经周期第3天口服雌激素预处理,术后放置宫内节育器防止再度粘连形成。术后1~2个月行2次宫腔探查,宫腔粘连程度采用AFS评分系统进行评价,术后随访1年内的妊娠情况(包括自然妊娠及辅助生殖)。结果:2次宫腔探查结果提示,2组患者宫腔形态的恢复程度差异无统计学意义(P>0.05);微型剪分离组的月经改善情况明显好于电切环分离组,微型剪分离组患者手术前后宫腔粘连评分的降低程度高于电切环分离组,差异均有统计学意义(P<0.05)。术后妊娠随访提示微型剪分离组患者术后妊娠率(43.6%)高于电切环分离组(37.2%)。结论:宫腔镜下宫腔粘连分离手术中,采用微型剪或者电切环均可在一定程度上改善宫腔形态和月经情况。在有生育要求的女性中,采用微型剪分离宫腔粘连可能更具优势。

宫腔镜微剪与电切割治疗子宫纵隔的对照研究

目的：比较宫腔镜微剪法与电切割法治疗子宫纵隔的临床疗效及安全性。方法：选取2009年1月-2011年12月行宫腔镜治疗的子宫纵隔患者58例，其中28例采用宫腔镜微剪法治疗（微剪组），30例行电切割法（电切割组）治疗。比较两组手术时间、膨宫液吸收量及妊娠结果。结果：微剪组与电切割组的一次性手术成功率分别为89．2％、100％，差异无统计学意义（ P＞0．05）；两组手术时间、膨宫液吸收量差异也均无统计学意义（均 P＞0．05）；两组均无严重并发症，随访6～36个月，微剪组妊娠成功率为75．0％，电切割组则为73．3％，差异无统计学意义（ P＞0．05）。结论：B超监护下宫腔镜微剪法与电切割法治疗子宫纵隔的疗效均满意，安全性好。

腹腔镜全子宫切除剪刀环形和电器械环形切开阴道穹窿在良性子宫病变中的疗效对比观察

目的探讨腹腔镜全子宫切除剪刀环形和电器械环形切口阴道穹窿在良性子宫病变中的临床治疗效果。方法选取2012年1月至2015年9月我院诊治的60例良性子宫病变患者随机分为两组,每组30例。对照组采用腹腔镜电器械环形切开阴道穹窿,实验组采用腹腔镜剪刀环形切开阴道穹窿,比较两组疗效。结果实验组术中出血量多于对照组(P<0.05);实验组手术时间、术后排气时间、住院时间与对照组比较无明显差异(P>0.05);实验组并发症发生率为3.3%,显著低于对照组的23.3%(P<0.05)。结论良性子宫病变患者采用腹腔镜全子宫切除剪刀环形切开阴道穹窿效果理想,能够提高临床疗效,降低并发症,值得推广应用。

电动汽车无线充电举升机构的设计与分析

随着电动汽车技术的不断完善,人们开始尝试着研究如何利用无线技术对电动汽车进行充电。为了提高无线充电的效率,文中提出了将剪叉机构用于无线充电发射板的举升的思想,通过分析系统特性确定电动推杆的运动情况,确立电动推杆速度与加速度曲线。通过剪叉机构的几何结构建立其力学、运动学分析模型。

利用电加热自动消毒修枝剪阻断梨火疫病田间传播

梨火疫病是近年传入我国的检疫性病害,由梨火疫病菌(Erwinia amylovora)引起,可通过修剪工具田间扩散加重危害。为阻断修剪工具传病途径,做好梨火疫病的有效防控,本研究测试了电加热自动消毒修枝剪的灭菌效果和阻断梨火疫病田间传播性能,结果表明:电加热自动消毒修枝剪在工作状态下可在1 s之内完全杀死沾染在刀片上的梨火疫病菌,田间实验表明电加热消毒剪可显著降低由修剪工具带菌造成的田间传播扩散,大面积田间应用也收到了非常好的应用效果。

基于Matlab遗传算法工具箱的剪叉机构推杆位置优化

某医用升降床以电动推杆为驱动实现剪叉机构的升降,电动推杆的安装位置不同会形成不同的推力曲线。在一定条件下,推杆形成的推力曲线影响升降系统的稳定性及剪叉臂的刚度和强度,因此,有必要对安装位置进行优化。文章通过虚位移法求得推杆的推力曲线数学表达式,采用Matlab遗传算法工具箱,对推杆位置进行设计研究和优化分析。遗传算法结果表明,改变推杆位置可使推杆最大推力减小,推力曲线得到优化。

Treatment of primary tracheal schwannoma with endoscopic resection:A case report

BACKGROUND Schwannoma is a benign tumor originating from the peripheral nerve sheath.The clinical symptoms of tracheal schwannoma depend on the location of the tumor,and the most common clinical symptoms are cough and hemoptysis.The most effective treatment for benign tumors is complete resection of the primary lesion at an early stage.Our experience has demonstrated that primary tracheal schwannoma can be safely excised with a high-frequency electric knife in a minimally invasive manner.CASE SUMMARY We report a 61-year-old asymptomatic woman who underwent chest computed tomography(CT),which accidentally found an intraluminal tracheal mass without enlarged lymph nodes.Then,the patient underwent bronchoscopy,which found that the tracheal mass originated from the left wall of the upper trachea,was less than 1.5 cm in size,immovable,smooth and 4 cm away from the vocal cord,resulting in partial upper respiratory tract obstruction.Treatment was performed using an endoscopic resection for en bloc removal of the tracheal mass.The diagnosis was primary tracheal schwannoma.A follow-up was performed after endoscopic surgery,and bronchoscopy and thoracic CT were used to monitor whether there was a recurrence.At present,there is no evidence of recurrence,and the patient had a good quality of life.Endoscopic resection may be effective and safe in the treatment of primary tracheal schwannoma.CONCLUSION Primary tracheal schwannoma is a very rare benign tumor.In this case,we cured it by complete endoscopic resection.

剪叉式高空作业平台举升机构参数匹配研究

剪叉式高空作业平台通常利用液压油缸驱动剪叉机构的伸缩,以此来控制平台的升降,但是这种方式存在液压油泄漏和能量利用率低的问题,为此,对基于电推杆驱动的举升机构动力参数进行了匹配研究。首先,以某型剪叉式高空作业平台为载体,构建了其举升机构的动力学模型,确定了电推杆在平台升降过程中的动力参数;然后,采用铰点优化方法对电推杆铰点安装位置进行了优化设计,并结合举升机构的性能指标要求,对电推杆相应的动力参数进行了匹配;最后,为了验证电推杆动力参数匹配的有效性,将电推杆与剪叉式高空作业平台的原始液压系统进行了性能对比实验。研究结果表明:在平台举升性能不变的情况下,经参数匹配后的电推杆可有效地完成油缸的动作要求,且其能量利用率比采用液压油缸举升方式提升约81.3%,可有效地满足举升机构的性能要求,在解决油缸液压油泄漏问题的同时,还可通过提高电能利用率来降低整车电池装机容量,从而达到有效降低整车制造成本的目的。

五金刀剪刃口厚度微小变化趋势精确测量系统

五金刀剪刀刃角度的稳定度(刀口横截面是否线性)在一定程度上决定着五金刀剪的性能。为了获得高精度刀剪刃口厚度微小变化趋势的精确测量系统,结合机电技术、单片机控制技术及测量与数据采集技术等,设计了一套精密测量系统,经过测试验证,该套五金刀剪刃口厚度微小变化趋势精确测量系统材料成本低廉、可行性和可靠性较强、有一定的实际应用价值。

双母线倒闸操作中剪刀式隔离刀闸的异常分析及改进

某变电站110 kV双管型母线布置方式下,在剪刀式隔离刀闸操作过程中动静触头没有完全接触紧密导致发生电弧。分析认为在倒母线的操作过程中,由于隔离开关支块和转轴之间生锈导致滑动摩擦增大改变操作行程,隔离开关不能实现电动操作失去电动力的冲击致使动静触头不能完全接触而放弧。提出了隔离开关机械传动部分和电动控制回路改造的相关建议和方案,经现场实施后,动静触头接触严密,没有发生过触头放弧现象。

Total Electricity Consumption Forecasting Based on Temperature Composite Index and Mixed-Frequency Models

The total electricity consumption(TEC)can accurately reflect the operation of the national economy,and the forecasting of the TEC can help predict the economic development trend,as well as provide insights for the formulation of macro policies.Nowadays,high-frequency and massive multi-source data provide a new way to predict the TEC.In this paper,a"seasonal-cumulative temperature index"is constructed based on high-frequency temperature data,and a mixed-frequency prediction model based on multi-source big data(Mixed Data Sampling with Monthly Temperature and Daily Temperature index,MIDAS-MT-DT)is proposed.Experimental results show that the MIDAS-MT-DT model achieves higher prediction accuracy,and the"seasonal-cumulative temperature index"can improve prediction accuracy.

基于无出血手术的高频电下鼻甲剪切仪的研制与应用

传统的下鼻甲手术剪只能单纯机械性剪切，由于鼻腔狭深、血运丰富，必然造成易出血而难止血。本文介绍一种基于无出血手术的新型的鼻科手术仪器──高频电下鼻甲剪切仪。该义器采用高频电控制技术及光源、负压吸引装置，具有剪切、止血、照明和吸引多种功能。临床应用表明：该仪器对解决术中、术后出血问题，具有良好效果。

高频电剪在会阴侧剪中的应用研究

目的:研究会阴侧剪术中高频电剪与传统侧剪专用工具之间的护理效果差异。方法:本文选择2014年4月-2015年4月来本院自然分娩的产妇226例,采用随机分组的方法,将其分为A组和B组,每组各113例患者。A组使用高频电剪进行侧切护理,B组使用传统手术刀进行侧切护理,比较两种手术器械对护理效果的影响。结果:A组患者Ⅰ度会阴损伤98例,Ⅱ度15例;B组患者Ⅰ度会阴损伤86例,Ⅱ度27例,两组患者均未发生Ⅲ度以上损伤,两组比较差异有统计学意义(P<0.05)。A组患者术后疼痛轻度102例,中度11例,B组患者术后疼痛轻度80例,中度33例,均未发生重度术后疼痛,两组比较差异有统计学意义(P<0.05)。结论:高频电剪更适应会阴侧剪术。