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Spatial Differentiation and Convergence Trend of High-quality Development Level of China’s Tourism Economy
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作者 CAO Shanshan HE Zhaoli +2 位作者 NIU Jinlan WANG Songmao ZHAO Lei 《Chinese Geographical Science》 SCIE CSCD 2024年第2期230-249,共20页
This paper aims to interpret the connotation of high-quality development of tourism economy(HQTE)from the perspective of the new development concepts of innovation,coordination,green,openness and sharing,and then to e... This paper aims to interpret the connotation of high-quality development of tourism economy(HQTE)from the perspective of the new development concepts of innovation,coordination,green,openness and sharing,and then to evaluate the spatial differenti-ation of China’s HQTE based on provincial panel data from 2009 to 2018.Specifically,we employ the spatial convergence model to ex-plore the absolute and conditionalβconvergence trends of HQTE in the whole country and the eastern,central and western regions of China.Our empirical results reveal that:1)within the decade,from 2009 to 2018,regions of China with the highest HQTE index is its eastern region followed by the central region and then the western region,but the fastest growing one is the western region of China fol-lowed by the central region and then the eastern region.2)Whether or not the spatial effect is included,there are absolute and condition-alβconvergence in HQTE in the whole country and aforementioned three regions.3)The degree of government attention as well as the level of economic development and location accessibility are the positive driving factors for the convergence of HQTE in the whole country and the three regions.The degree of marketization and human capital have not passed the significance test either in the whole country or in the three regions.The above conclusions could deepen the understanding of the regional imbalance and spatial conver-gence characteristics of HQTE,clarify the primary development objects,and accomplish the goal of China’s HQTE. 展开更多
关键词 new development concepts high-quality development of tourism economy(HQTE) spatial convergence China
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Addressing inclusion,innovation,and sustainability challenges through the lens of economic geography:Introducing the hierarchical regional innovation system
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作者 Iván Tartaruga Fernanda Sperotto Luís Carvalho 《Geography and Sustainability》 CSCD 2024年第1期1-12,共12页
The world is facing dramatic challenges related to environmental sustainability at an accelerating pace.In this context,the field of economic geography(EG)has been playing an important role in understanding both the s... The world is facing dramatic challenges related to environmental sustainability at an accelerating pace.In this context,the field of economic geography(EG)has been playing an important role in understanding both the socioeconomic and technological dimensions of these challenges,as it deals with a variety of complementary notions and perspectives.Departing from this lens,our aim is to explore a conceptual framework that can help us to understand environmental changes relating to multi-dimensional territorial development,notably in eco-nomic contexts where inequality is high,and stratification based on hierarchies regulate social and economic life.Based on the territory concept,we propose the original notion of a hierarchical regional innovation system(HRIS)that emphasises the pervasive role of hierarchies(powers)in regional innovation systems and illustrate its value with evidence and case studies from extant literature on sustainability transitions.The HRIS can help us understand and promote development paths considering the contribution of inclusive eco-innovations(another original conceptual amalgam).Through some empirical cases from other studies in low-carbon transitions,we show the application of the HRIS(and inclusive eco-innovation)framework.In conclusion,we provide incen-tives to explore new regional innovation systems,alongside the HRIS,adapted to different regions worldwide and centred on the inclusiveness of people and places. 展开更多
关键词 Inclusive eco-innovation Inclusive innovation Hierarchical regional innovation system(HRIS) Territorial development Sustainable development Sustainability transitions
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Genetic mechanisms of high-quality tight siliciclastic reservoirs:A case study from the Upper Triassic Xujiahe Formation in the Yuanba area,Sichuan Basin,China
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作者 Ai Wang Junlong Liu +4 位作者 Zhongqun Liu Kaihua Xiao Yanqing Huang Lingxiao Fan Jitong Li 《Energy Geoscience》 EI 2024年第3期151-162,共12页
This study analyzed the petrological characteristics,diagenesis,pore types,and physical properties of the tight coarse-grained siliciclastic sequences in the third member of the Upper Triassic Xujiahe Formation(also r... This study analyzed the petrological characteristics,diagenesis,pore types,and physical properties of the tight coarse-grained siliciclastic sequences in the third member of the Upper Triassic Xujiahe Formation(also referred to as the Xu-3 Member)in the western Yuanba area in the northeastern Sichuan Basin,China,based on the results of 242.61-m-long core description,292 thin-section observations,scanning electron microscopy(SEM),and 292 physical property tests.The types and genetic mechanisms of high-quality tight coarse-grained siliciclastic reservoirs in this member was determined thereafter.The research objective is to guide the exploration and development of the tight coarse-grained siliciclastic sequences in the Xu-3 Member.The results of this study are as follows.Two types of high-quality reservoirs are developed in the coarse-grained siliciclastic sequences of the Xu-3 Member,namely the fractured fine-grained sandy conglomerate type and porous medium-grained calcarenaceous sandstone type.Hydrodynamic energy in the sedimentary environment is the key factor controlling the formation of high-quality reservoirs.These high-quality reservoirs are developed mainly in the transitional zone with moderately high hydrodynamic energy between delta-plain braided channels and delta-front subaqueous distributary channels.The dolomitic debris(gravel)content is the main factor affecting the reservoirs’physical properties.The micritic algal debris and sandy debris in the dolomitic debris(or gravels)tend to recrystallize during burial,forming intercrystalline pores within.In the medium-grained calcarenaceous sandstones,intercrystalline pores in the dolomitic debris are formed at the early diagenetic stage,and a pore system consisting of structural fractures connecting intergranular pores,intergranular dissolution pores,and kaolinite intergranular micropores is developed at the late stage of diagenesis.The formation of intercrystalline pores in dolomite gravels and gravel-edge fractures,a pore system connected by gravel-edge and tectonic fractures,is closely related to the dolomite gravels in the sandy fine-grained conglomerates. 展开更多
关键词 Tight siliciclastic rock high-quality reservoir Genetic mechanism Xujiahe Formation Northeast Sichuan
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Effects of high-quality neurosurgical nursing care on improving clinical nursing quality
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作者 Xiu-Rong Li Qing-Lian Luo 《World Journal of Clinical Cases》 SCIE 2024年第22期4999-5007,共9页
BACKGROUND With continuous advancements in medical technology,neurosurgical nursing is constantly developing and improving to provide higher-quality nursing services.AIM To explore the effects of different types of hi... BACKGROUND With continuous advancements in medical technology,neurosurgical nursing is constantly developing and improving to provide higher-quality nursing services.AIM To explore the effects of different types of high-quality nursing care on clinical nursing quality and patient satisfaction in neurosurgical nursing.METHODS Eighty patients who received neurosurgical treatment in the Affiliated Hospital of Southwest Medical University from June to December 2020 were selected as study participants and categorised into study and control groups.The study group comprised 40 patients who received 4 different types of high-quality nursing care,whereas the control group comprised 40 patients who received conventional nursing care.After a specific period,nursing satisfaction levels and adverse event and complication rates were compared between the two groups.RESULTS Satisfaction with high-quality care was higher than that with conventional care,and high-quality health services and regional services showed the highest satisfaction levels,with an average score of 12 on the Glasgow scale.The satisfaction levels of the study and control groups were 75%and 57%,respectively,with a statistically significant difference(t=7.314,P<0.05).During the nursing period,the adverse event and complication rates were the highest in patients with level III pathology grade and those who underwent neurosurgery(40.02%and 85.93%,respectively),and the difference was statistically significant.CONCLUSION In neurosurgical nursing,employing appropriate high-quality nursing methods can effectively reduce adverse event and complication rates in patients,thereby improving the quality of nursing care and increasing clinical nursing value. 展开更多
关键词 high-quality nursing NEUROSURGERY Quality care Adverse event COMPLICATION
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Research on Innovation-Driven Expansion of Regional OFDI: New Evidence From a Business Environment Perspective
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作者 Duan Longlong Li Qingyi 《Contemporary Social Sciences》 2024年第1期75-98,共24页
This paper investigates the impact of provincial innovation-driven efficiency on the expansion of regional Outward Foreign Direct Investment(OFDI)flows within the context of China’s economy during the period 2011 to ... This paper investigates the impact of provincial innovation-driven efficiency on the expansion of regional Outward Foreign Direct Investment(OFDI)flows within the context of China’s economy during the period 2011 to 2020 by measuring the innovation-driven efficiency and business environment index using the DEA-Malmquist index and the combined CRITIC weighting method from the new perspective of business environment improvement.The findings reveal that:(a)There is an inverted U-shaped relationship between provincial innovation-driven efficiency and regional OFDI flows.This increase in innovation-driven efficiency can promote OFDI expansion of the region by improving its business environment.(b)The improvement of the business environments plays a significant intermediary and synergistic role in OFDI expansion driven by improved innovation efficiency.(c)The study of regional heterogeneity suggests that the central region enjoys the longest window period in terms of innovation-driven OFDI expansion,followed by the eastern region while the western region has the shortest window period.The improvement of the business environment in the western region is more effective in driving regional OFDI expansion.This conclusion remained true after the robustness test.In conclusion,this paper offers a few policy recommendations that can help Chinese capital of various kinds go global more effectively. 展开更多
关键词 innovation as a driver innovation efficiency OFDI expansion business environment
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High-quality Development Path of Graduate Education in Aquaculture Discipline:A Case Study of Guangdong Ocean University
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作者 Huanying PANG Miao XIE +2 位作者 Shuanghu CAI Yucong HUANG Jichang JIAN 《Asian Agricultural Research》 2024年第9期41-44,共4页
Aquaculture is a discipline system that focuses on exploring the growth,development,reproduction,aquaculture,and resources of aquatic animals and plants,and their complex relationships.Under the tide of the"high-... Aquaculture is a discipline system that focuses on exploring the growth,development,reproduction,aquaculture,and resources of aquatic animals and plants,and their complex relationships.Under the tide of the"high-quality development"strategy,the aquaculture discipline is also facing new opportunities and challenges for transformation,upgrading,and deepening development.Therefore,exploring and practicing an effective path for the high-quality development of graduate education in aquaculture is not only the key to promoting the transformation of graduate education in aquaculture from scale expansion to quality improvement,but also has immeasurable value for implementing the strategy on developing a quality workforce and the strategy of scientific and technological powerhouse.The high-quality development of graduate education in aquaculture can be promoted from the following aspects:optimizing and improving the construction of the graduate education system,focusing on enhancing the quality of high-level talent cultivation,strengthening the overall strength of the graduate supervisor team,actively promoting the adjustment and upgrading of the disciplinary and professional structure,strengthening the construction of resource platforms and deepening the implementation of collaborative education mechanisms,and continuously expanding and deepening the new pattern of international exchange and cooperation.Through the comprehensive promotion of the above paths,the aim is to fully build a model for the improvement and governance of graduate education quality. 展开更多
关键词 AQUACULTURE Graduate education high-quality development
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Exploring Paths for the High-Quality Development of Forest-Based Wel ness Industry:A Case Study of Sichuan Province
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作者 Jin Xiaoqin Li Jing 《Contemporary Social Sciences》 2024年第3期77-91,共15页
The forest-based wellness industry,as a rapidly growing sector that integrates various business forms with extensive coverage and an extended industrial chain,is undergoing rapid development due to the increasing agin... The forest-based wellness industry,as a rapidly growing sector that integrates various business forms with extensive coverage and an extended industrial chain,is undergoing rapid development due to the increasing aging population and people's suboptimal health conditions.As a forerunner in developing the forest-based wellness industry,Sichuan province is known for its early development,proactive efforts,diverse models,and significant impact in this industry.It has achieved certain milestones in terms of top-level design,pilot demonstration,standardized guidance,and public awareness campaigns to promote the development of this industry.Therefore,this paper utilizes Sichuan as a case study to systematically summarize and analyze the key practices made by the province in promoting the rapid development of the industry by investigating the development trajectory of the forest-based wellness industry.Additionally,it examines the development trends of this industry from the perspectives of supply,demand,and consumption.Finally,this paper proposes several measures to facilitate the high-quality development of the forest-based wellness industry.These measures encompass nurturing specialized talent in forest-based wellness,enhancing market players'capabilities in this domain,conducting extensive research on technologies that promote this industry,actively seeking support from relevant policies,and promoting integrated development across diverse sectors. 展开更多
关键词 forest-based wellness industry high-quality development Sichuan province
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Improving innovation and entrepreneurship education in higher institutions: the impact of "Mass Entrepreneurship and Innovation" education on undergraduates' entrepreneurial intentions 被引量:1
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作者 ShaoYing Lu Sun Ye +1 位作者 XiaoShu Xu Yuwei Zhao 《教育技术与创新》 2024年第1期10-26,共17页
The exploration of the way"mass entrepreneurship and innovation"(MEI)education influences students'aspirations to become entrepreneurs has grown into an important area of analysis in studies related to h... The exploration of the way"mass entrepreneurship and innovation"(MEI)education influences students'aspirations to become entrepreneurs has grown into an important area of analysis in studies related to higher education.This research intends to examine the consequences of MEI education on students'tendency towards entrepreneurship,and to put forward methods for augmenting the teaching of innovation and entrepreneurship in private higher educational establishments.To achieve this objective,questionnaires and semi-structured interviews were employed in the study,which involved a total of 197 students and five education experts.The statistical analysis of the questionnaire data revealed that MEI education was positively related to students'entrepreneurial intentions,and that both entrepreneurial experience and family entrepreneurial background played moderating roles in this relationship.The interview findings indicated that private universities could enhance educational reforms by designing talent training programs,developing diversified curricula,and developing more professional entrepreneurial platforms to encourage students'entrepreneurial intentions.This study offers fresh insights for improving and perfecting the mechanism of innovation and entrepreneurship education in private universities. 展开更多
关键词 Private universities Mass Entrepreneurship and innovation MEI education entrepreneurial intention
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How does network intermediary affect collaborative innovation?Evidence from Chinese listed companies
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作者 Zhiwei Zhang Wenhao Zhou 《Journal of Data and Information Science》 CSCD 2024年第4期49-70,共22页
Purpose:This study aims to explore how network intermediaries influence collaborative innovation performance within inter-organizational technological collaboration networks.Design/methodology/approach:This study empl... Purpose:This study aims to explore how network intermediaries influence collaborative innovation performance within inter-organizational technological collaboration networks.Design/methodology/approach:This study employs a mixed-method approach,combining quantitative social network analysis with regression techniques to investigate the role of network intermediaries in collaborative innovation performance.Using a patent dataset of Chinese industrial enterprises,the research constructs the collaboration networks and analyzes their structural positions,particularly focusing on their role as intermediaries,characterized by betweenness centrality.Negative binomial regression analysis is employed to assess how these network characteristics shape innovation outcomes.Findings:The study reveals that firms in intermediary positions enhance collaborative innovation performance,but this effect is nuanced.A key finding is that network clustering negatively moderates the intermediary-innovation relationship.Highly clustered networks,while fostering local collaboration,may limit the innovation potential of intermediaries.On the other hand,relationship strength,measured by collaboration intensity and trust among firms,positively moderates the intermediary-innovation link.Research limitations:This study has several limitations that present opportunities for further research.The reliance on quantitative social network analysis may overlook the complexity of intermediaries’roles,and future studies could benefit from incorporating qualitative methods to better understand cultural and institutional factors.Additionally,cross-country comparisons are needed to assess the consistency of these dynamics in different contexts.Practical implications:The study offers practical insights for firms and policymakers.Organizations should strategically position themselves as network intermediaries to access diverse information and resources,thereby improving innovation performance.Building strong trust helps using network intermediary advantages.For firms in highly clustered networks,it is important to seek external partners to avoid limiting their exposure to new ideas and technologies.This research emphasizes the need to balance network diversity with relationship strength for sustained innovation.Originality/value:This research contributes to the literature by offering new insights into the role of network intermediaries,presenting a comprehensive framework for understanding the interaction between network dynamics and firm innovation. 展开更多
关键词 Network intermediary Collaborative innovation Social network Relationship strength
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The Impact of Digital Finance on High-Quality Development of the Chengdu-Chongqing Economic Circle
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作者 Wei Liangyi Bai Xiaobo Li Qin 《Contemporary Social Sciences》 2024年第2期1-15,共15页
This paper developed a comprehensive evaluation system that was able to quantify the levels of high-quality development across the cities within the Chengdu-Chongqing economic circle,and investigate the impact that di... This paper developed a comprehensive evaluation system that was able to quantify the levels of high-quality development across the cities within the Chengdu-Chongqing economic circle,and investigate the impact that digital finance had on the cities’high-quality development and the underlying mechanisms through which it achieved this.This comprehensive evaluation system was constructed using statistical data from these cities for the period 2014 to 2020 while also taking China’s high-quality development philosophy into account.The key findings revealed that:(a)Digital finance was able to significantly promote high-quality development in the Chengdu-Chongqing economic circle;(b)Digital finance had a significant positive effect in promoting innovative,coordinated,green,open,and shared development;(c)Digital finance was able to stimulate the high-quality development in the Chengdu-Chongqing economic circle by boosting entrepreneurial dynamism;(d)Digital finance had a significant impact on the high-quality development of the axis areas,while its impact was less discernible in non-axis areas.The insights from this research offer a deeper understanding of the factors that drive high-quality development,the role digital finance plays,and the mechanisms through which digital finance is able to propel high-quality development at the city cluster scale. 展开更多
关键词 digital finance Chengdu-Chongqing economic circle high-quality development
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The Future of Environmental Engineering Technology:A Disruptive Innovation Perspective
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作者 Hui Huang Junjie Lu +1 位作者 Lili Jin Hongqiang Ren 《Engineering》 SCIE EI CAS CSCD 2024年第10期153-160,共8页
Scientific and technological revolutions and industrial transformations have accelerated the rate of innovation in environmental engineering technologies.However,few researchers have evaluated the current status and f... Scientific and technological revolutions and industrial transformations have accelerated the rate of innovation in environmental engineering technologies.However,few researchers have evaluated the current status and future trends of technologies.This paper summarizes the current research status in eight major subfields of environmental engineering—water treatment,air pollution control,soil/solid waste management,environmental biotechnology,environmental engineering equipment,emerging contaminants,synergistic reduction of pollution and carbon emissions,and environmental risk and intelligent management—based on bibliometric analysis and future trends in greenization,low carbonization,and intelligentization.Disruptive technologies are further identified based on discontinuous transformation,and ten such technologies are proposed,covering general and specific fields,technical links,and value sources.Additionally,the background and key innovations in disruptive technologies are elucidated in detail.This study not only provides a scientific basis for strategic decision-making,planning,and implementation in the environmental engineering field but also offers methodological guidance for the research and determination of breakthrough technologies in other areas. 展开更多
关键词 Environmental engineering technology Disruptive innovation Bibliometric analysis Discontinuous transformation
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Data-Empowered High-Quality Economic Development: Mechanisms and Pathways
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作者 Xia Jiechang Zheng Hao Zhang Yajun 《China Economist》 2024年第3期39-48,共10页
To achieve high-quality economic development,it is imperative to prioritize the real economy and foster new factors for economic growth.Data,as a new factor of production,plays a pivotal role in facilitating the seaml... To achieve high-quality economic development,it is imperative to prioritize the real economy and foster new factors for economic growth.Data,as a new factor of production,plays a pivotal role in facilitating the seamless integration between digital technology and the real economy.It possesses inherent attributes and techno-economic characteristics that enable the extraction of value across various processes,including production,transaction,consumption,and regulatory supervision.The integration with digital technology enhances the productivity and efficiency of the real economy by facilitating service sector digitalization,accelerating the growth of the new real economy,and supporting the virtual economy in its role of serving the real economy.At present,unleashing the value of data is hindered by inadequate fundamental systems for the data,a lack of activity in the transaction market,and the underutilization of the data as a factor of production by enterprises in the real economy.Therefore,it is advised that data be fully utilized to develop the real economy through the four-pronged approach of“enhancing support for the high-quality provision of the data,expediting the integration of the data into the real economy,promoting the high-quality development of the real economy,and enhancing public service and governance systems”. 展开更多
关键词 Real economy data digital economy high-quality development
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Innovation and Firm Co-ownership Network in China’s Electric Vehicle Industry
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作者 JIN Zerun ZHU Shengjun 《Chinese Geographical Science》 SCIE CSCD 2024年第2期195-209,共15页
Firms are embedded in complex networks,where diverse ideas combine and generate new ideas.Shareholders of firms are of-ten seen as critical external resources that have significant influence on firm innovation.The cur... Firms are embedded in complex networks,where diverse ideas combine and generate new ideas.Shareholders of firms are of-ten seen as critical external resources that have significant influence on firm innovation.The current literature tends to focus on the rela-tionship between firms and their shareholders,while paying less attention to the connections between firms with the same shareholders.This article identifies two types of network spillover effects,intra-city network effect and inter-city network effect,by visualizing the co-ownership networks in China’s electric vehicle(EV)industry.We find that firms with the same shareholders,which are defined as co-owned EV firms,are more innovative than non-co-owned ones.Furthermore,there are two dominant types of firm co-ownership ties formed by corporate and financial institution shareholders.While corporate shareholders help exploiting local tacit knowledge,financial institutions are more active in bridging inter-city connections.The conclusion is confirmed at both firm and city levels.This paper theor-izes the firm co-ownership network as a new form of institutional proximity and tested the result empirically.For policy consideration,we have emphasized the importance of building formal or informal inter-firm network,and the government should further enhance the knowledge flow channel by institutional construction. 展开更多
关键词 firm co-ownership intra-city network inter-city network technological innovation electric vehicle China
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The Mediating Effect of Digital Transformation on the Link Between Executive Overconfidence and Corporate Green Innovation
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作者 Zhu Yong Zhu Beibei 《Contemporary Social Sciences》 2024年第5期51-69,共19页
Green technological innovation is crucial for the manufacturing industry’s green transformation and sustainable development.This study examines the impact of executive overconfidence on corporate green innovation,foc... Green technological innovation is crucial for the manufacturing industry’s green transformation and sustainable development.This study examines the impact of executive overconfidence on corporate green innovation,focusing on the internal drivers of corporate innovation and using a sample of Shanghai and Shenzhen A-share listed manufacturing companies from 2013 to 2020.We further examine the mediating role of digital transformation and the moderating role of external attention.The findings indicate that executive overconfidence promotes corporate green technological innovation.Overconfident executives enhance green innovation by accelerating digital transformation.Moreover,external attention from analysts and media positively moderates the relationship between executive overconfidence and corporate green innovation.Heterogeneity analysis reveals that the positive impact of executive overconfidence on green innovation is more significant in non-state-owned enterprises,high-tech firms,and enterprises with lower pollution levels. 展开更多
关键词 executive overconfidence digital transformation green innovation
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Surgeon Perspectives on Anastomotic Leaks and FluidAI’s StreamTM Platform: Integrating Qualitative Insights for Technological Innovation
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作者 Olivia Rennie Manaswi Sharma Nour Helwa 《Surgical Science》 2024年第8期492-500,共9页
Purpose: This article investigates the critical importance of integrating surgeons’ direct input into the development of innovative technologies that address gaps in surgical care, including those aimed at reducing a... Purpose: This article investigates the critical importance of integrating surgeons’ direct input into the development of innovative technologies that address gaps in surgical care, including those aimed at reducing anastomotic leaks (AL), a major complication in gastrointestinal surgery. While traditional quantitative research methods are prevalent, they often overlook the invaluable insights of the surgeons who manage these complications firsthand. Subjects and Methods: This study employs a qualitative approach, utilizing semi-structured interviews with 40 surgeons from various specialties, including general, bariatric, colorectal, trauma, hepato-biliary, and thoracic surgery. The interviews were designed to probe the needs of surgeons, challenges currently faced, and gaps in clinical practice, research, and technology for detection and/or management of AL. The data were analyzed using thematic analysis, which revealed significant gaps in current technologies for early detection and prevention of leaks. Results: Surgeons expressed strong interest in FluidAI’s Stream™ Platform, a non-invasive medical device designed to monitor postoperative drainage fluid in real-time, providing continuous data on AL risk. The ability of this platform to offer early prediction through pH and electrical conductivity analysis was particularly appealing to participants, who emphasized the importance of timely interventions in improving patient outcomes. The study’s findings highlight not only the clinical challenges but also the emotional toll that AL takes on surgeons, underlining the need for innovations that are both data-driven and humanistic. Conclusion: By centering surgeons’ perspectives, this research advocates for a human-centered approach to technological advancement, ensuring that new tools are both clinically effective and aligned with the real-world needs of surgical practitioners. 展开更多
关键词 Anastomotic Leaks Surgeon Perspectives Postoperative Complications Qualitative Inquiry Technological innovation
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Fast-to-Clinic, Fast-to-Market in Biotech Innovation: Optimizing Chemistry Manufacturing & Controls (CMC) Excellence for Clinical and Commercial Success
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作者 Kishore Kumar Hotha 《Advances in Chemical Engineering and Science》 CAS 2024年第3期155-171,共17页
In the emerging world of biotech innovation, the fast-to-clinic/market strategy has emerged as a critical “mantra” for biotech, investors, and CDMOs. This approach addresses the escalating costs and complexities of ... In the emerging world of biotech innovation, the fast-to-clinic/market strategy has emerged as a critical “mantra” for biotech, investors, and CDMOs. This approach addresses the escalating costs and complexities of research and development by streamlining the path from concept to clinical trials and, ultimately, to market. The article delves into the intricacies of implementing a fast-to-clinic/market strategy, underlining the empowering role of strategic decision-making in preclinical and commercial stages. The plan advocates for a phase-appropriate approach, where the development decision is tailored to each phase of the product’s lifecycle. This ensures that resources are allocated efficiently, risks are managed effectively, and the product can move through the development pipeline accelerated without compromising quality or regulatory compliance. The article also discusses the role of CDMOs in facilitating rapid product development and the essential factors biotech companies must consider when selecting a partner for outsourcing. These factors include the CDMO’s expertise in navigating regulatory landscapes, technological capabilities, and ability to scale processes efficiently. Moreover, the article stresses the importance of agility and flexibility in the fast-to-clinic/market approach. Biotech companies are encouraged to adopt adaptable strategies that respond to the fast-evolving regulatory and market landscapes. 展开更多
关键词 Fast to Clinic innovation CDMO CMC PRECLINICAL FDA IND NDA ANDA BIOTECH
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Cultivation Path of Nursing Undergraduates’Scientific Research and Innovation Ability
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作者 Guanying Yang Yuan Zhao 《Journal of Biosciences and Medicines》 2024年第5期202-212,共11页
Objective: The cultivation of the innovation ability and scientific research is one of the nursing learning objectives for undergraduate students. To explore the method and effect of training system of scientific rese... Objective: The cultivation of the innovation ability and scientific research is one of the nursing learning objectives for undergraduate students. To explore the method and effect of training system of scientific research innovation ability of nursing undergraduates based on “3332”. Methods: Three course learning modules are constructed: stage-based course learning module, systematic project practice training module and comprehensive practice training module. A practical training platform for scientific research innovation projects is built, and undergraduate scientific research innovation ability training is carried out from both in-class and out-of-class lines. Results: Since 2017, the students have obtained 7 national innovation and entrepreneurship training programs, 52 university-level undergraduate scientific research projects, published more than 10 academic papers, and obtained 2 patent authorization. Conclusions: The training system of scientific research innovation ability of nursing undergraduates based on “3332” is conducive to the development of scientific research innovation ability of nursing students, and to cultivate nursing talents who can adapt to the development of the new era and have better post competence. 展开更多
关键词 Nursing Undergraduates Scientific Research innovation Ability Learning Module Cultivation Path
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Coordination Mechanism and Empirical Research on Marine Science Technology Innovation and Marine Eco-civilization:A Case Study of Coastal Areas of China
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作者 CHEN Xiaolong LIANG Chenlu DI Qianbin 《Chinese Geographical Science》 SCIE CSCD 2024年第3期468-486,共19页
Marine science technology innovation provides power and guarantees for marine eco-civilization construction,which provides direction and material support for marine science technology innovation.Therefore,the coordina... Marine science technology innovation provides power and guarantees for marine eco-civilization construction,which provides direction and material support for marine science technology innovation.Therefore,the coordinated development of the two is of great significance to the marine economy sustainable development in China’s coastal areas.On the basis of clarifying the connotations of marine science technology innovation and marine eco-civilization in China’s coastal areas from 2006 to 2019,the mechanism for their coordinated development was analysed.A comprehensive indicator system based on the connotation of the two was constructed,and the coordinated development relationship was empirically tested using the coupled coordination model and the panel vector autoregressive(PVAR)model.The results show that:1)the level of China’s coastal marine science technology innovation continues to improve,gradually forming the core of the development of marine science technology innovation in the north,east and south of Shandong,Shanghai and Guangdong;the level of marine eco-civilization development fluctuating upward trend,showing obvious spatial differentiation characteristics.2)The degree of coordination of marine science technology innovation and marine eco-civilization is growing over time.There is no causal relationship between marine science technology innovation and marine eco-civilization in the northern marine economic circle,but there is a two-way causal relationship between the two in the eastern and southern marine economic circles.3)Marine eco-civilization shows a significant positive and continuous impact on marine science technology innovation,and marine science technology innovation shows a long-term,continuous,fluctuating,and lagging impact on marine eco-civilization.The overall role of marine eco-civilization on marine science technology innovation is dominant,and there are significant differences in the impact effects of the two major marine economic circles. 展开更多
关键词 marine science technology innovation marine eco-civilization coordinated development coastal areas of China
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Thoughts on Pairing Assistance to Tibet for Promoting Agricultural High-quality Development in Southern Tibet from the Perspective of Agricultural Power
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作者 Zhiguo SUN Li GAO +3 位作者 Yuanpeng SUN Guangchao CAO Xinying ZHOU Xiaoqiang LI 《Asian Agricultural Research》 2024年第3期18-24,共7页
In the new era,there is an urgent need to further promote pairing assistance to Tibet,promote the simultaneous construction of a strong agriculture in Tibet and the China's Mainland,and compose a Chinese-style mod... In the new era,there is an urgent need to further promote pairing assistance to Tibet,promote the simultaneous construction of a strong agriculture in Tibet and the China's Mainland,and compose a Chinese-style modernization.Southern Tibet,located in the southeastern part of the Tibet Autonomous Region,includes Shannan City and Nyingchi City,is a region assisted by four provincial partners including Hubei Province.This paper introduces the agricultural environment in southern Tibet,studies its agricultural characteristics,and analyzes the main issues of its pairing assistance.Taking forging the strong consciousness of the Chinese national community as the main line,the paper explores strategies for promoting agricultural high-quality development in southern Tibet through pairing assistance to Tibet from the perspective of agricultural power,and proposes some strategies,such as inheriting agricultural cultural heritage,promoting the upgrading of modern seed industry,enhancing the characteristic advantages of highland barley(naked barley)and animal husbandry industries,and developing edible fungi and cold water fish industries. 展开更多
关键词 PAIRING ASSISTANCE to TIBET Southern TIBET Shannan CITY Nyingchi CITY AGRICULTURAL high-quality development AGRICULTURAL power
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How to promote cooperative innovation in environmentally friendly technology:a case of agricultural biotechnology in China
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作者 Hongkun Ma Xian Mi +5 位作者 Yi Zheng Ning Lv Shan Zhang Chunting Hu Xiaowei Wu Yuan Cao 《Chinese Journal of Population,Resources and Environment》 2024年第2期127-135,共9页
This study explored the factors influencing cooperative innovation in environmentally friendly agricultural biotechnology in China.First,we constructed an evolutionary game model comprising the factors of net income o... This study explored the factors influencing cooperative innovation in environmentally friendly agricultural biotechnology in China.First,we constructed an evolutionary game model comprising the factors of net income of cooperative innovation,net income of independent innovation,market constraints,and government subsidies.Using MATLAB simulation,we assigned different values to the aforementioned variables to explore the evolutionary trend of innovators’willingness to cooperate.Results showed that when the values of net income of cooperative innovation,net income of independent innovation,market constraints,and government subsidies exceeded the threshold,innovators’willingness to cooperate was significantly enhanced.Furthermore,the proportion of innovators who cooperated with others gradually increased to 100%;otherwise,it gradually decreased to 0%.Comparing the simulation curve with the real evolution curve of cooperative innovation in agricultural biotechnology in China,we found that the gradual decline in the willingness to cooperate could be due to insufficient subsidies for cooperative innovation,low income from cooperative innovation,weak profitability of innovators,and weak market constraints. 展开更多
关键词 Cooperative innovation Evolutionary game MATLAB Simulation Agricultural biotechnology Environmentally friendly technology
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