The Reform and Practice of Multicultural Cultivation Mode of Art Talents in Colleges and Universities Under the Strategy of “Three Highs and Four New”

As an important link in the development of modern quality education,art education is one of the methods to guide students to have a diversified vision.Under the background of multiculturalism,we need to explore the connotation and value of art education with the concept of“three highs and four new,”so that students can realize interdisciplinary and cross-cultural cognition through an immersive experience and practical operation in a wide range of multicultural situations,and to develop the knowledge of art education with the concept of“three highs and four new.”Based on the multicultural background,this paper focuses on the integration of multiculturalism into the reform practice of“student-centered”in colleges and universities,so as to cultivate art talents adapted to the multicultural background,in order to achieve the great mission of“three highs and four new”and better lead the innovative development of art education in colleges and universities.

A salt-induced tackifying polymer for enhancing oil recovery in highsalinity reservoirs:Synthesis,evaluation,and mechanism

Polymerflooding is an effective method widely applied for enhancing oil recovery(EOR)by reducing the mobility ratio between theinjected water and crude oil.However,traditional polymers encounter challenges in high salinity reservoirs due to their salt sensitivity.Toovercome this challenge,we synthesized a zwitterion polymer(PAMNS)with salt-induced tackifying property through copolymerization ofacrylamide and a zwitterion monomer,methylacrylamide propyl-N,N-dimethylbutylsulfonate(NS).NS monomer is obtained from thereaction between 1,4-butanesultone and dimethylamino propyl methylacrylamide.In this study,the rheological properties,salt responsiveness,and EOR efficiency of PAMNS were evaluated.Results demonstrate that PAMNS exhibits desirable salt-induced tackifyingcharacteristics,with viscosity increasing up to 2.4 times as the NaCl concentration reaches a salinity of 30×10^(4)mg L^(-1).Furthermore,highvalence ions possess a much stronger effect on enhancing viscosity,manifested as Mg^(2+)>Ca^(2+)>Na^(+).Molecular dynamics simulations(MD)andfluid dynamics experiment results demonstrate that PAMNS molecules exhibit a more stretched state and enhanced intermolecularassociations in high-salinity environments.It is because of the salt-induced tackifying,PAMNS demonstrates superior performance inpolymerflooding experiments under salinity ranges from 5×10^(4)mg L^(-1)to 20×10^(4)mg L^(-1),leading to 10.38–19.83%higher EOR thantraditional polymers.

Response of global subtropical highs to the equatorial eastern Pacific SST anomaly

Based on the reanalysis data of global 500hPa geopotential height (NCEP NCAR CDAS-1) and tropical Pacific SSTs, the characteristics of global subtropical highs and their response to tropical eastern Pacific SST are investigated. Results show that global subtropical highs respond to SST consistently. Subtropical high intensity correlates to the 3 months leading SST maximally. The relationship between SST and 500hPa height stands out in low latitudes. The time for 500hPa height reaching maximuxn correlation to SST is 2 months later in latitude of 10 degree and 9 months in latitude of 30 degree than equatorial zone. And the response of atmospheric circulation over extratropic performs as wave train, and the response is more significant in the condition of warmer SST. Persistence of SSTs and subtropical highs changes obviously from season to season. Minimum persistence of subtropical highs in September and October may relate to the low persistence of SSTs in August and September.

Money Flowing into Commodities Powers Cotton to Fresh Rally Highs

Money flowing into commodities-one analyst called it a "commodity pandemonium" - powered cotton futures to new rally highs last week in holiday-shortened trading.

Numerical Simulation of the Effect of the SST Anomalies in the Tropical Western Pacific on the Blocking Highs over the Northeastern Asia

The effects of the sea surface temperature (SST) anomalies in the tropical western Pacific on the atmospheric circulation anomalies over East Asia are simulated by the IAP-GCM with an observed and idealized distributions of the SST anomalies in the tropical western Pacific,respectively.Firstly,the atmospheric circulation anomalies during July and August,1980 are simulated by three anomalous experiments including the global SST anomaly experiment,the tropical SST anomaly experiment and the extratropical SST anomaly experiment,using the observed SST anomalies in 1980.It is shown that the SST anomalies in the tropical ocean greatly influence the formation and maintenance of the blocking high over the northeastern Asia,and may play a more important role than the SST anomalies in the extratropical ocean in the influence on the atmospheric circulation anomalies.Secondly,the effects of the SST anomalies in the tropical western Pacific on the atmospheric circulation anomalies over East Asia are also simulated with an idealized distribution of the SST anomalies in the tropical western Pacific.The simulated results show that the negative anomalies of SST in the tropical western Pacific have a significant effect on the formation and maintenance of the blocking high over the northeastern Asia.

Remote Impact of Blocking Highs on the Sudden Track Reversal of Tropical Cyclones

Previous work showed that some tropical cyclones （TCs） in the western Pacific Ocean undergo sudden track reversal, and the onset, maintenance and decay of blocking highs （BHs） coexisted with 19 of the studied TCs with sudden track reversal. In these cases, the phase relations between the BH, the continental high （CH）, the subtropical high （SH） and the suddenly reversed TCs could be classified into types A, B, C and D. Types C and D were the focal point of this follow-up study, in which Typhoon Pabuk （2007） and Lupit （2009） were employed to conduct numerical simulations. The results showed that the reversed tracks of Pabuk （2007） and Lupit （2009） could have been affected by the BH, particularly in terms of the turning location and the trend of movement after turning. Specifically, the two main features for Pabuk （2007） in the BH perturbations were the deflection of its turning point and a distinct anticlockwise rotation. Lupit （2009） deviated to the southwest and finally made landfall in the Philippines, or experienced further eastward movement, in the perturbed BH. The impact mechanisms can be attributed to the change in the vorticity field transported from the BH, leading to an intensity variation of midlatitude systems. BHs may have a positive feedback effect on the strength of the westerly trough （TR）, as indicated by a weakened and strengthened TR corresponding to negative and positive BH perturbations, respectively.

Elderly patients with non-cardiac admissions and elevated highsensitivity troponin:the prognostic value of renal function

BACKGROUND High-sensitivity cardiac troponin(hs-cTn)levels are frequently elevated in elderly patients presenting to the emergency department for non-cardiac events.However,most studies on the role of elevated hs-cTn in elderly populations have investigated the prognostic value of hs-cTn in patients with a specific diagnosis or have assessed the relationship between hs-cTn and comorbidities.AIM To investigate the in-hospital prognosis of consecutive elderly patients admitted to the Internal Medicine Department with acute non-cardiac events and increased hs-cTnI levels.METHODS In this retrospective study,we selected patients who were aged≥65 years and admitted to the Internal Medicine Department of our hospital between January 2019 and December 2019 for non-cardiac reasons.Eligible patients were those who had hs-cTnI concentrations≥100 ng/L.We investigated the independent predictors of in-hospital mortality by multivariable logistic regression analysis.RESULTS One hundred and forty-six patients(59%female)were selected with an age range from 65 to 100(mean±SD:85.4±7.61)years.The median hs-cTnI value was 284.2 ng/L.For 72(49%)patients the diagnosis of hospitalization was an infectious disease.The overall in-hospital mortality was 32%(47 patients).Individuals who died did not have higher hs-cTnI levels compared with those who were discharged alive(median:314.8 vs 282.5 ng/L;P=0.565).There was no difference in mortality in patients with infectious vs non-infectious disease(29%vs 35%).Multivariable analysis showed that age(OR 1.062 per 1 year increase,95%CI:1.000-1.127;P=0.048)and creatinine levels(OR 2.065 per 1 mg/dL increase,95%CI:1.383-3.085;P<0.001)were the only independent predictors of death.Mortality was 49%in patients with eGFR<30 mL/min/1.73 m2.CONCLUSION Myocardial injury is a malignant condition in elderly patients admitted to the hospital for non-cardiac reasons.The presence of severe renal impairment is a marker of extremely high in-hospital mortality.

Research on the design of ballastless track in the subgrade section of highspeed railway in high earthquake-intensity area

According to the characteristics of complex terrain and bad geological conditions in the southwest mountainous area of China, it is proposed that cast-in situ double-block ballastless track with layers and blocks structure should be adopted preferentially in the subgrade section of high-speed railway, which is conducive to the construction, prolongation of service life and maintenance of the ballastless track. Based on the finite element model, the dynamic performance, structural strength and stability of double-block ballastless track under high earthquake-intensity action are analyzed. The analysis shows that the relative displacement between the base slab of ballastless track and the subgrade may occur under 9 degree earthquake action. A new CRTS double-block ballastless track structure with a concave-convex structure between the base slab and the subgrade is proposed in the subgrade section, and its additional stress and relative displacement under earthquake are analyzed. The results show that the additional stress and relative displacement of the new ballastless track structure and the subgrade under 9-degree earthquake actions are small, which meet the high stability requirements of high-speed railway.

China’s carbon neutrality faces the challenges of“three highs and one short”,and requires“five carbon implementations”to achieve dual carbon goals

Dual carbon goals are closely related to high-quality green development.The government has required that dual car-bon goals be included in ecological civilization construction’s overall layout.Achieving carbon peak and carbon neutrality is a broad and profound systemic economic and social transformation.China is facing the“three highs and one short”challenges and requires the“five carbon implementations”to achieve dual carbon goals.The core of dual carbon goals is a new round of industrial competition,and the world is laying out dual carbon goals as the starting point and competing for a new round of technological high ground.

Energetics of Boreal Wintertime Blocking Highs around the Ural Mountains

Based on the daily Japanese 55-yr reanalysis data,this study analyzes the maintenance mechanism for 53 boreal winter blocking highs around the Ural Mountains(UBHs)during 1958-2018 based on the atmospheric energy budget equations.After decomposing the circulation into background flow,low-frequency anomalies,and high-frequency eddies,it was found that the interaction between the background flow and low-frequency anomalies is conducive to the maintenance of the UBHs.Due to the southwestward gradient in the climatological mean air temperature over the Eurasian continent,it is easy for the air temperature anomalies as well as the wind velocity anomalies in the middle and lower troposphere induced by the UBHs to facilitate the positive conversion of baroclinic energy associated with the background flow into the UBHs.Likewise,the conversion of barotropic energy associated with the background flow is also evident in the upper troposphere,in which the climatological mean westerlies have evident southward gradient to the northwest of Lake Baikal and southwestward gradient over Barents Sea.Note that the conversion of baroclinic energy associated with the background flow is dominant throughout the lifecycle of UBHs,acting as the major contributor to the maintenance of the UBHs.Although transient eddies facilitate maintenance of the UBHs via positive conversion of barotropic energy in the middle and upper troposphere,they hinder the maintenance of UBHs via negative conversion of baroclinic energy in the lower troposphere.The diabatic heating anomalies tend to counteract the local air temperature anomalies in the middle and lower troposphere,which damps the available potential energy of UBHs and acts as a negative contributor to the UBHs.

Sulfolane‑Based Flame‑Retardant Electrolyte for High‑Voltage Sodium‑Ion Batteries

Sodium-ion batteries hold great promise as next-generation energy storage systems.However,the high instability of the electrode/electrolyte interphase during cycling has seriously hindered the development of SIBs.In particular,an unstable cathode–electrolyte interphase(CEI)leads to successive electrolyte side reactions,transition metal leaching and rapid capacity decay,which tends to be exacerbated under high-voltage conditions.Therefore,constructing dense and stable CEIs are crucial for high-performance SIBs.This work reports localized high-concentration electrolyte by incorporating a highly oxidation-resistant sulfolane solvent with non-solvent diluent 1H,1H,5H-octafluoropentyl-1,1,2,2-tetrafluoroethyl ether,which exhibited excellent oxidative stability and was able to form thin,dense and homogeneous CEI.The excellent CEI enabled the O3-type layered oxide cathode NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2)(NaNMF)to achieve stable cycling,with a capacity retention of 79.48%after 300 cycles at 1 C and 81.15%after 400 cycles at 2 C with a high charging voltage of 4.2 V.In addition,its nonflammable nature enhances the safety of SIBs.This work provides a viable pathway for the application of sulfolane-based electrolytes on SIBs and the design of next-generation high-voltage electrolytes.

High Fe‑Loading Single‑Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

The current single-atom catalysts(SACs)for medicine still suffer from the limited active site density.Here,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs by exchanging zinc with iron.The constructed iron SACs(h^(3)-FNC)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial effects.Attractively,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNCs by 2.3 times compared to low-and medium-loading SACs.Consequently,the overall catalytic activity of h^(3)-FNC is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/C.In addition,h^(3)-FNCs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)depletion.Both in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNCs in promoting wound healing.This work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections.

Challenges and improvement strategies in the hospitalization of chronic multimorbid patients

BACKGROUND Addressing the growing challenge of hospitalizing chronic multimorbid patients,this study examines the strain these conditions impose on healthcare systems at a local level,focusing on a pilot program.Chronic diseases and complex patients require comprehensive management strategies to reduce healthcare burdens and improve patient outcomes.If proven effective,this pilot model has the potential to be replicated in other healthcare settings to enhance the management of chronic multimorbid patients.AIM To evaluate the effectiveness of the high complexity unit(HCU)in managing chronic multimorbid patients through a multidisciplinary care model and to compare it with standard hospital care.METHODS The study employed a descriptive longitudinal approach,analyzing data from the Basic Minimum Data Set(BMDS)to compare hospitalization variables among the HCU,the Internal Medicine Service,and other services at Antequera Hospital throughout 2022.The HCU,designed for patients with complex chronic conditions,integrates a patient-centered model emphasizing multidisciplinary care and continuity post-discharge.RESULTS The study employed a descriptive longitudinal approach,analyzing data from the BMDS to compare hospitalization variables among the HCU,the Internal Medicine Service,and other services at Antequera Hospital throughout 2022.The HCU,designed for patients with complex chronic conditions,integrates a patient-centered model emphasizing multidisciplinary care and continuity post-discharge.CONCLUSION This study demonstrates the effectiveness of the HCU in managing patients with complex chronic diseases through a multidisciplinary approach.The coordinated care provided by the HCU results in improved patient outcomes,reduced unnecessary hospitalizations,and better management of patient complexity.The superiority of the HCU compared to standard care is evident in key outcomes such as fewer readmissions and higher patient satisfaction,reinforcing its value as a model of care to be replicated.

High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and neuroscience.High-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain injury.Several drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system disorders.Although it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system disorders.In this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory role.Research targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

EFFECT OF LOCAL BASIC FLOW STRUCTURE PATTERN IN FORMATION OF BLOCKING HIGHS

The effect of local basic flow structure pattern(BFSP)on a blocking high formation is investigated within the framework of forced dissipation KDV dynamics.The zonal and meridional positions of the high's center excited by a heat source depend on the BFSP selected.

ACTUAL ANALYSIS AND THEORETICAL SIMULATION ON POSITION OF SUBTROPICAL HIGHS OVER WESTERN PACIFIC

In this paper,using a nonlinear low-order barotropic system with orography and momentum forcing as well as dissipation,we have theoretically calculated the two kinds of curves for the seasonal northward movement of subtropical highs.It has been shown that the theoretical results resemble basically with the analysed results of wave spectrum data.

Maturing Relations——China and South Korea push bilateral relations to new highs

For decades after the founding of the People ’s Republic of China in 1949,China and the Republic of Korea were sworn enemies.

Ten highs and lows of the 07 auto market

The auto market had a better year as a whole in 2006, thanks to forces of locally-owned brands and economical cars. And the market is expected to maintain its soaring momentum, with the

A bHLH transcription factor,CsSPT,regulates high-temperature resistance in cucumber

High-temperature stress threatens the growth and yield of crops. Basic helix-loop-helix(bHLH) transcription factors(TFs) have been shown to play important roles in regulating high-temperature resistance in plants. However, the bHLH TFs responsible for high-temperature tolerance in cucumbers have not been identified. We used transcriptome profiling to screen the high temperature-responsive candidate bHLH TFs in cucumber. Here, we found that the expression of 75 CsbHLH genes was altered under high-temperature stress. The expression of the CsSPT gene was induced by high temperatures in TT(Thermotolerant) cucumber plants. However, the Csspt mutant plants obtained by the CRISPR-Cas9 system showed severe thermosensitive symptoms, including wilted leaves with brown margins and reduced root density and cell activity.The Csspt mutant plants also exhibited elevated H_(2)O_(2) levels and down-regulated photosystem-related genes under normal conditions.Furthermore, there were high relative electrolytic leakage(REC), malondialdehyde(MDA), glutathione(GSH), and superoxide radical(O_(2)^(·-)) levels in the Csspt mutant plants, with decreased Proline content after the high-temperature treatment. Transcriptome analysis showed that the photosystem and chloroplast activities in Csspt mutant plants were extremely disrupted by the high-temperature stress compared with wildtype(WT) plants. Moreover, the plant hormone signal transduction, as well as MAPK and calcium signaling pathways were activated in Csspt mutant plants under high-temperature stress. The HSF and HSP family genes shared the same upregulated expression patterns in Csspt and WT plants under high-temperature conditions. However, most bHLH, NAC, and bZIP family genes were significantly down-regulated by heat in Csspt mutant plants. Thus, these results demonstrated that CsSPT regulated the high-temperature response by recruiting photosynthesis components, signaling pathway molecules, and transcription factors. Our results provide important insights into the heat response mechanism of CsSPT in cucumber and its potential as a target for breeding heat-resistant crops.

基于高空平台的边缘计算卸载:网络、算法和展望

高空平台(high altitude platform,HAP)技术与多接入边缘计算(multi-access edge computing,MEC)技术的结合将MEC服务器部署区域由地面扩展到空中,打破传统地面MEC网络的局限性,为用户提供无处不在的计算卸载服务。针对基于HAP的MEC卸载研究进行综述,首先,从HAP计算节点的优势、网络组成部分、网络结构、主要挑战及其应对技术4个方面分析基于HAP的MEC网络;其次,分别从图论、博弈论、机器学习、联邦学习等理论的角度对基于HAP的MEC卸载算法进行横向分析和纵向对比;最后,指出基于HAP的MEC卸载技术目前存在的问题,并对该技术的未来研究方向进行展望。