<div style="text-align:justify;"> Herein we have originally designed chiral azo-salen Mn(II) and Zn(II) complexes for interacting silver nanoparticles (AgNPs) exhibiting localized surface plasmon reson...<div style="text-align:justify;"> Herein we have originally designed chiral azo-salen Mn(II) and Zn(II) complexes for interacting silver nanoparticles (AgNPs) exhibiting localized surface plasmon resonance (LSPR). Understanding excited state and reaction intermediate during light irradiation to return to ground state may be important for such composite systems. Therefore, we investigated such optical properties for systems using time-resolved luminescence and transient absorption measurements. DMSO solutions of the four newly prepared and characterized complexes (<strong>MMn</strong><strong>, MZn, CMn,</strong> and <strong>CZn</strong>) and ethanol solutions of the composite materials of each complex with AgNPs were served for optical measurements. The time-correlated single photon counting (TCSPC), the streak camera which is much shorter period of time than TCSPC and transient absorption measurement, was performed for the eight samples. The fluorescence lifetime of the sole complexes and the composite materials with AgNPs was derived from curve-fitting analysis of luminescence decay curves of TCSPC. Lifetime of the composite systems with AgNPs was longer than that of the corresponding sole metal complexes for three cases. It was revealed that composite systems may go through three reaction intermediates during relaxation from excited state to ground state. </div>展开更多
In this study,a novel class of histidine Schiff base silver（Ⅰ） complexes derived from salicylaldehyde,1a-9a,was found to be an effective inhibitor of α-glucosidase.The results of this study showed that the newly s...In this study,a novel class of histidine Schiff base silver（Ⅰ） complexes derived from salicylaldehyde,1a-9a,was found to be an effective inhibitor of α-glucosidase.The results of this study showed that the newly synthesized complexes inhibited α-glucosidase through noncompetitive mechanisms;the IC50values were ranging from 0.00431 μmol L ~1 to 0.492 μmol L ~1.The structure-activity relationship was established as well.These results demonstrated that compound 7a,5-nitro salicylaldehyde Schiff base silver complex,is the most promising α-glucosidase inhibitor with the lowest IC50 value,which could be exploited as a drug candidate to alleviate postprandial hyperglycemia in the treatment of type II diabetes mellitus.This research provided a catalyst-free,simple,and environmentally benign reaction to synthesize compounds using mechanochemistry.展开更多
Five silver(Ⅰ) complexes with Schiff bases obtained from salicylaldehyde and five corresponding α-amino acids were synthesized. The complexes were characterized by elemental analysis, IR and 1H NMR measurements. Bio...Five silver(Ⅰ) complexes with Schiff bases obtained from salicylaldehyde and five corresponding α-amino acids were synthesized. The complexes were characterized by elemental analysis, IR and 1H NMR measurements. Bioactivity tests showed that the complexes inhibited the cucumber mosaic virus. Among them the best effective was glycine salicylaldehyde Schiffbase Ag(Ⅰ), which gave the effective level up to 74.7% towards CMV in dosage of 400 mg/L(in case of phaseolus vulgarisl inoculation).展开更多
A new hexanuclear silver （I） compound 2 containing thiosemicarbazone with the group of benzene was synthesized and structurally characterized by single-crystal X-ray diffraction, elemental analysis and fluorescence ...A new hexanuclear silver （I） compound 2 containing thiosemicarbazone with the group of benzene was synthesized and structurally characterized by single-crystal X-ray diffraction, elemental analysis and fluorescence spectrum. The title compound crystallizes in triclinic, space group P with a = 11.611（3）, b = 15.610（5）, c = 15.624（7） , α = 113.942（6）, β = 104.520（6）, γ = 104.230（4）°, V = 2304.1（14） 3, C60H77Ag6N22O4.5S6, Mr = 2018.02, Dc = 1.454 g/cm3, μ（MoKα） = 1.435 mm-1, F（000） = 1005, Z = 1, the final R = 0.0468 and wR = 0.1474 for 6608 observed reflections （I 2σ（I））. In the structure, the S atom of the ligand L2 （L2 = benzaldehyde thiosemicarbazone） served as a triply bridged chelator to connect the six silver atoms into a Ag6L26 cluster. The luminescence property of compound 2 was investigated at room temperature.展开更多
A new di-Schiff base ligand, 1,2-bis(3′-pyridylmethyleneamino)ethane(L), was designed and its Ag(Ⅰ) complex[Ag 2(L) 2](CF 3SO 3) 2 was synthesized. The crystal structure analysis indicates that the complex crystalli...A new di-Schiff base ligand, 1,2-bis(3′-pyridylmethyleneamino)ethane(L), was designed and its Ag(Ⅰ) complex[Ag 2(L) 2](CF 3SO 3) 2 was synthesized. The crystal structure analysis indicates that the complex crystallizes in monoclinic system, space group of C2/c with a=3.770 4(2) nm, b=0.797 90(10) nm, c=2.471 3(2) nm, β=101.840(10)°, V=7.276 5(12) nm 3, Z=8, D c=1.808 g/cm 3, \{F(000)=\}3 936, R=0.058 3, wR=0.076 6, (Δρ) max=0.657×10 3 e/nm 3,(Δρ) min=-0.562×10 3 \{e/nm 3\}. It is interesting that one L ligand coordinates to three Ag(Ⅰ) atoms using four N atoms, while another L ligand connects two Ag(Ⅰ) atoms with three of four N atoms and one N atom keeps free of coordination.展开更多
文摘<div style="text-align:justify;"> Herein we have originally designed chiral azo-salen Mn(II) and Zn(II) complexes for interacting silver nanoparticles (AgNPs) exhibiting localized surface plasmon resonance (LSPR). Understanding excited state and reaction intermediate during light irradiation to return to ground state may be important for such composite systems. Therefore, we investigated such optical properties for systems using time-resolved luminescence and transient absorption measurements. DMSO solutions of the four newly prepared and characterized complexes (<strong>MMn</strong><strong>, MZn, CMn,</strong> and <strong>CZn</strong>) and ethanol solutions of the composite materials of each complex with AgNPs were served for optical measurements. The time-correlated single photon counting (TCSPC), the streak camera which is much shorter period of time than TCSPC and transient absorption measurement, was performed for the eight samples. The fluorescence lifetime of the sole complexes and the composite materials with AgNPs was derived from curve-fitting analysis of luminescence decay curves of TCSPC. Lifetime of the composite systems with AgNPs was longer than that of the corresponding sole metal complexes for three cases. It was revealed that composite systems may go through three reaction intermediates during relaxation from excited state to ground state. </div>
文摘In this study,a novel class of histidine Schiff base silver（Ⅰ） complexes derived from salicylaldehyde,1a-9a,was found to be an effective inhibitor of α-glucosidase.The results of this study showed that the newly synthesized complexes inhibited α-glucosidase through noncompetitive mechanisms;the IC50values were ranging from 0.00431 μmol L ~1 to 0.492 μmol L ~1.The structure-activity relationship was established as well.These results demonstrated that compound 7a,5-nitro salicylaldehyde Schiff base silver complex,is the most promising α-glucosidase inhibitor with the lowest IC50 value,which could be exploited as a drug candidate to alleviate postprandial hyperglycemia in the treatment of type II diabetes mellitus.This research provided a catalyst-free,simple,and environmentally benign reaction to synthesize compounds using mechanochemistry.
文摘Five silver(Ⅰ) complexes with Schiff bases obtained from salicylaldehyde and five corresponding α-amino acids were synthesized. The complexes were characterized by elemental analysis, IR and 1H NMR measurements. Bioactivity tests showed that the complexes inhibited the cucumber mosaic virus. Among them the best effective was glycine salicylaldehyde Schiffbase Ag(Ⅰ), which gave the effective level up to 74.7% towards CMV in dosage of 400 mg/L(in case of phaseolus vulgarisl inoculation).
基金supported by the Postdoctoral Science Foundation of Central South University
文摘A new hexanuclear silver （I） compound 2 containing thiosemicarbazone with the group of benzene was synthesized and structurally characterized by single-crystal X-ray diffraction, elemental analysis and fluorescence spectrum. The title compound crystallizes in triclinic, space group P with a = 11.611（3）, b = 15.610（5）, c = 15.624（7） , α = 113.942（6）, β = 104.520（6）, γ = 104.230（4）°, V = 2304.1（14） 3, C60H77Ag6N22O4.5S6, Mr = 2018.02, Dc = 1.454 g/cm3, μ（MoKα） = 1.435 mm-1, F（000） = 1005, Z = 1, the final R = 0.0468 and wR = 0.1474 for 6608 observed reflections （I 2σ（I））. In the structure, the S atom of the ligand L2 （L2 = benzaldehyde thiosemicarbazone） served as a triply bridged chelator to connect the six silver atoms into a Ag6L26 cluster. The luminescence property of compound 2 was investigated at room temperature.
文摘A new di-Schiff base ligand, 1,2-bis(3′-pyridylmethyleneamino)ethane(L), was designed and its Ag(Ⅰ) complex[Ag 2(L) 2](CF 3SO 3) 2 was synthesized. The crystal structure analysis indicates that the complex crystallizes in monoclinic system, space group of C2/c with a=3.770 4(2) nm, b=0.797 90(10) nm, c=2.471 3(2) nm, β=101.840(10)°, V=7.276 5(12) nm 3, Z=8, D c=1.808 g/cm 3, \{F(000)=\}3 936, R=0.058 3, wR=0.076 6, (Δρ) max=0.657×10 3 e/nm 3,(Δρ) min=-0.562×10 3 \{e/nm 3\}. It is interesting that one L ligand coordinates to three Ag(Ⅰ) atoms using four N atoms, while another L ligand connects two Ag(Ⅰ) atoms with three of four N atoms and one N atom keeps free of coordination.
