Logical resonance has been demonstrated to be present in the Fitz Hugh-Nagumo(FHN)neuron,namely,the FHN neuron can operate as a reliable logic gate within an optimal parameter window.Here we attempt to extend the resu...Logical resonance has been demonstrated to be present in the Fitz Hugh-Nagumo(FHN)neuron,namely,the FHN neuron can operate as a reliable logic gate within an optimal parameter window.Here we attempt to extend the results to the more biologically realistic Hodgkin-Huxley(HH)model of neurons.In general,biological organisms have an optimal temperature at which the biological functions are most effective.In view of this,we examine if there is an optimal range of temperature where the HH neuron can work like a specific logic gate,and how temperature influences the logical resonance.Here we use the success probability P to measure the reliability of the specific logic gate.For AND logic gate,P increases with temperature T,reaches the maximum in an optimal window of T,and eventually decreases,which indicates the occurrence of the temperature-induced logical resonance phenomenon in the HH neuron.Moreover,single and double logical resonances can be induced by altering the frequency of the modulating periodic signal under the proper temperatures,suggesting the appearance of temperature-controlled transition of logical resonance.These results provide important clues for constructing neuron-based energy-efficient new-fashioned logical devices.展开更多
基于霍尔效应原理和Hodgkin-Huxley模型,研究经颅霍尔效应刺激对神经元系统放电节律的影响作用。研究表明,当超声和静磁场在神经元中产生的电流强度从10μA/cm2到55μA/cm2逐渐增大时,神经元动作电位的峰值从96 m V减小到71 m V,峰峰间...基于霍尔效应原理和Hodgkin-Huxley模型,研究经颅霍尔效应刺激对神经元系统放电节律的影响作用。研究表明,当超声和静磁场在神经元中产生的电流强度从10μA/cm2到55μA/cm2逐渐增大时,神经元动作电位的峰值从96 m V减小到71 m V,峰峰间期从15 ms减小到8.5 ms,发放率从4～6呈多级阶梯状逐渐增大。研究还发现,当超声的发射周期从6～100 ms逐渐增大时,神经元动作电位的发放率从1～5呈多级阶梯状逐渐增大。研究结果揭示经颅霍尔效应刺激对神经元放电节律的作用规律,有助于探索经颅霍尔效应刺激对神经精神类疾病治疗和康复的机理。展开更多
基金This Project supported by the National Natural Science Foundation of China (Grant No.11804111)。
文摘Logical resonance has been demonstrated to be present in the Fitz Hugh-Nagumo(FHN)neuron,namely,the FHN neuron can operate as a reliable logic gate within an optimal parameter window.Here we attempt to extend the results to the more biologically realistic Hodgkin-Huxley(HH)model of neurons.In general,biological organisms have an optimal temperature at which the biological functions are most effective.In view of this,we examine if there is an optimal range of temperature where the HH neuron can work like a specific logic gate,and how temperature influences the logical resonance.Here we use the success probability P to measure the reliability of the specific logic gate.For AND logic gate,P increases with temperature T,reaches the maximum in an optimal window of T,and eventually decreases,which indicates the occurrence of the temperature-induced logical resonance phenomenon in the HH neuron.Moreover,single and double logical resonances can be induced by altering the frequency of the modulating periodic signal under the proper temperatures,suggesting the appearance of temperature-controlled transition of logical resonance.These results provide important clues for constructing neuron-based energy-efficient new-fashioned logical devices.
文摘基于霍尔效应原理和Hodgkin-Huxley模型,研究经颅霍尔效应刺激对神经元系统放电节律的影响作用。研究表明,当超声和静磁场在神经元中产生的电流强度从10μA/cm2到55μA/cm2逐渐增大时,神经元动作电位的峰值从96 m V减小到71 m V,峰峰间期从15 ms减小到8.5 ms,发放率从4～6呈多级阶梯状逐渐增大。研究还发现,当超声的发射周期从6～100 ms逐渐增大时,神经元动作电位的发放率从1～5呈多级阶梯状逐渐增大。研究结果揭示经颅霍尔效应刺激对神经元放电节律的作用规律,有助于探索经颅霍尔效应刺激对神经精神类疾病治疗和康复的机理。
