期刊文献+
共找到341篇文章
< 1 2 18 >
每页显示 20 50 100
New scoring system in assessment of Hoffa's fat pad synovitis: A comparative study with established scoring systems 被引量:3
1
作者 Shigeo Hagiwara Albert Yang +3 位作者 Shoichiro Takao Yasuhito Kaneko Taiki Nozaki Hiroshi Yoshioka 《World Journal of Radiology》 2018年第11期162-171,共10页
AIM To investigate the reliability of the established and new scoring methods for Hoffa's fat pad synovitis using magnetic resonance imaging(MRI).METHODS A total of 139 knees of 115 patients who underwent MRI of t... AIM To investigate the reliability of the established and new scoring methods for Hoffa's fat pad synovitis using magnetic resonance imaging(MRI).METHODS A total of 139 knees of 115 patients who underwent MRI of the knee with and without gadolinium contrast were enrolled in this study. Proton density(PD)-weighted, PD-weighted fat-suppressed(PD-FS), and postcontrast T1-weighted fat-suppressed(T1CE) images were used for evaluation. Using contrast and noncontrast images, our grading method for synovitis was performed to measure synovial thickness and signal intensity changes of the fat pad [Synovial membrane(SM) score], which was compared with the established methods,including MRI Osteoarthritis Knee Score(MOAKS), parapatellar synovitis score,Whole-Organ Magnetic Resonance Imaging Score(WORMS), and suprapatellar effusion diameter. Intraclass correlation coefficients(ICC) for intra and interobserver reproducibility and Spearman correlation coefficients(r) were calculated for the parapatellar synovitis score and each scoring method.RESULTS All of the scores presented substantial to almost perfect intrareliability. Among three readers, effusion diameter had substantial to almost perfect interreliability(ICC = 0.68-0.81) and WORMS had substantial interreliability(ICC = 0.61-0.70).For two out of three readers, there was substantial interreliability for the thickness score in T1CE(ICC = 0.55-0.69), SM scores in T1CE(ICC = 0.56-0.78)and PD-FS(ICC = 0.51-0.79), and parapatellar synovitis score in T1CE(ICC =0.53-0.72). The parapatellar synovitis score was significantly correlated with the thickness score in T1CE(r = 0.70) and the SM score in T1CE(r = 0.81) and PD-FS(r = 0.65).CONCLUSION The newly proposed quantitative thickness score on T1CE and the semiquantitative SM score on T1CE and PD-FS can be useful for Hoffa's fat pad synovitis. 展开更多
关键词 Magnetic resonance imaging Hoffa’s fat pad SYNOVITIS Semiquantitative SCORE Quantitative SCORE SCORING system
下载PDF
Fat management in upper blepharoplasty:Addition or subtraction blepharoplasties,how and when
2
作者 Giovanni Miotti Jacopo Di Filippo +6 位作者 Martina Grando Carlo Salati Pier Camillo Parodi Leopoldo Spadea Caterina Gagliano Mutali Musa Marco Zeppieri 《World Journal of Clinical Cases》 SCIE 2024年第16期2796-2802,共7页
BACKGROUND As one of the most common aesthetic surgical procedures carried out today,blepharoplasty should be in the repertoire of every plastic surgeon.The term blepharoplasty encompasses a wide range of techniques a... BACKGROUND As one of the most common aesthetic surgical procedures carried out today,blepharoplasty should be in the repertoire of every plastic surgeon.The term blepharoplasty encompasses a wide range of techniques and options that must be tailored to the specific defect and patient one has to treat.A sound knowledge of the upper and lower eyelids’anatomy is essential for proper surgical execution.Trends have shifted towards more conservative methods(especially of the fat compartment)and sometimes in combination with augmentation techniques,helping to reach a rejuvenated appearance.AIM To present an overview of the surgical techniques considered for upper lid blepharoplasty and fat pad management,in addition to information on how a surgeon may approach the best treatment for his patient based on current publications in literature.METHODS We searched the literature published between 2013,to 2023 using Medline and Reference Citation Analysis.The database was searched using the keywords“upper blepharoplasty”AND“fat”.Papers without full text/abstracts and reviews were excluded.The search strategy followed the PRISMA.The American Society of Plastic Surgeons guidelines for Therapeutic Studies checklist was used to assess all articles.Two authors individually reviewed each article and rated them for importance and relevance to the topic.A consensus was sought and the most relevant studies.RESULTS After the application of the selection criteria used in our review,13 publications were found to address upper lid blepharoplasty specifically.Three of these studies were reviews and three were retrospective studies.Five publications were comparative studies and a further two were clinical trials.CONCLUSION The tendency of modern surgery is to be conservative,by removing adipose tissue only if strictly necessary and restoring the volume of the upper eyelid in a concept of beauty that espouses a"full"sight.There is no gold standard technique to achieve younger and enhanced eyelids.Long-term prospective comparative studies are fundamental in understanding which path is the best to follow. 展开更多
关键词 BLEPHAROPLASTY fat pads Eye lid surgery Cosmetic aesthetic surgery REJUVENATION Plastic surgery
下载PDF
Role of infrapatellar fat pad in pathological process of knee osteoarthritis: Future applications in treatment 被引量:4
3
作者 Li-Feng Jiang Jing-Hua Fang Li-Dong Wu 《World Journal of Clinical Cases》 SCIE 2019年第16期2134-2142,共9页
It has been found that obese people have a higher proportion in suffering from osteoarthritis (OA),not only in the weight-bearing joints like knee and hip joints,even in non-weight-bearing joints such as hand joints.O... It has been found that obese people have a higher proportion in suffering from osteoarthritis (OA),not only in the weight-bearing joints like knee and hip joints,even in non-weight-bearing joints such as hand joints.One of the reasons is because the large amount of adipose tissue secretes some factors,which can promote the occurrence of arthritis.As an important structure of the knee joint,the infrapatellar fat pad (IPFP) is actually a piece of adipose tissue.The aim of this review is to offer a comprehensive view of the anatomy and physiological characteristics of IPFP and its relationship with the pathological process of OA,indicating the important function of IPFP in OA.At the same time,with the development of adipose derived stem cells in the treatment of OA,owing to its special advantages,the IPFP is becoming a kind of important,minimally invasive fat stem cell source,providing a new approach for the treatment of OA.We hope that this review will offer an overview of all published data regarding the IPFP and will indicate novel directions for future research. 展开更多
关键词 Infrapatellar fat pad OSTEOARTHRITIS Human MESENCHYMAL stem cells
下载PDF
Orthognathic Surgery Combined with Partial Lipectomy of the Buccal Fat Pad: Case Report on Optimization of Esthetic Outcome 被引量:1
4
作者 Daniel Amaral Alves Marliere Caio Bellini Lovisi +2 位作者 Alan Robert Moreira Schmitt Bruno Salles Sotto-Maior Henrique Duque de Miranda Chaves Netto 《Journal of Pharmacy and Pharmacology》 2017年第8期565-571,共7页
Orthognathic surgery involves correction of functional and often esthetic disharmonies. The purpose of this case report is topresent the case of a 22 years-old female with class III dentofacial deformity that required... Orthognathic surgery involves correction of functional and often esthetic disharmonies. The purpose of this case report is topresent the case of a 22 years-old female with class III dentofacial deformity that required orthognathic surgery to treat hermalocclusion and buccal fat pad excision for optimizing soft-tissue facial contour. Treatment planning involved a counterclockwiserotation of the maxilomandibular complex with genioplasty based on digital 3D surgical planning using the Dolphin Imaging 11.7 3DPremium software. Prototyping splints allowed surgical procedures (bilateral sagital mandibular osteotomy associated to a Le fort Iosteotomy) that corrected position of the gnathic bones. In the same surgical procedure, the buccal fat pad was partially removed for asharp cheek contour giving a slimmer appearance to her face. After 5 months, the patient was reassessed and reported no complaintsregarding esthetics or function. This case illustrates that a combination oforthognathic surgery and an esthetic procedure can result in astable and harmonious facial as well as occlusal outcomes. 展开更多
关键词 ORTHOGNATHIC surgery occlusal plane malocclusion BUCCAL fat pad AESTHETIC procedure.
下载PDF
Reliability of the pronator quadratus fat pad sign to predict the severity of distal radius fractures 被引量:2
5
作者 Julia Loesaus Isabel Wobbe +2 位作者 Erik Stahlberg Joerg Barkhausen Jan Peter Goltz 《World Journal of Radiology》 CAS 2017年第9期359-364,共6页
AIM To evaluate the reliability of pronator quadratus fat pad sign to detect distal radius fracture and to predict its severity.METHODS Retrospectively we identified 89 consecutive patients(41 female, mean age 49 ... AIM To evaluate the reliability of pronator quadratus fat pad sign to detect distal radius fracture and to predict its severity.METHODS Retrospectively we identified 89 consecutive patients(41 female, mean age 49 ± 18 years) who had X-ray(CR) and computed tomography(CT) within 24 h following distal forearm trauma. Thickness of pronator quadratus fat pad complex(PQC) was measured using lateral views(CR) and sagittal reconstructions(CT). Pearson's test was used to determine the correlation of the PQC thickness in CR and CT. A positive pronator quadratus sign(PQS) was defined as a PQC > 8.0 mm(female) or > 9.0 mm(male). Frykman classification was utilized to assess the severity of fractures.RESULTS Forty-four/89 patients(49%) had a distal radius fracture(Frykman Ⅰ n = 3, Ⅱ n = 0, Ⅲ n = 10, Ⅳ n = 5, Ⅴ n = 2, Ⅵ n = 2, Ⅶ n = 9, Ⅷ n = 13). Mean thickness of the PQC thickness can reliably be measured on X-ray views and was 7.5 ± 2.8 mm in lateral views(CR), respectively 9.4 ± 3.0 mm in sagittal reconstructions(CT), resulting in a significant correlation coefficientof 0.795. A positive PQS at CR was present in 21/44 patients(48%) with distal radius fracture and in 2/45 patients(4%) without distal radius fracture, resulting in a specificity of 96% and a sensitivity of 48% for the detection of distal radius fractures. There was no correlation between thickness of the PQC and severity of distal radius fractures.CONCLUSION A positive PQS shows high specificity but low sensitivity for detection of distal radius fractures. The PQC thickness cannot predict the severity of distal radius fractures. 展开更多
关键词 旋前肌 quadratus 脂肪垫符号 旋前肌 quadratus 建筑群 远侧的半径骨折 Frykman 分类 常规拍 计算断层摄影术
下载PDF
NEEDLING THREE POINTS AROUND THE KNEE-JOINT FOR TREATMENT OF 138 CASES OF INFRAPATELLAR FAT PAD STRAIN
6
作者 舒洪文 《World Journal of Acupuncture-Moxibustion》 1996年第3期51-53,共3页
Infrapatellar fat pad strain is a common disease and is referred to the chronic cumu-lative lesion of the knee joint, manifested mainly as arthralgia. The author treated 100 cases ofthis disease by noedling Neixiyan(E... Infrapatellar fat pad strain is a common disease and is referred to the chronic cumu-lative lesion of the knee joint, manifested mainly as arthralgia. The author treated 100 cases ofthis disease by noedling Neixiyan(EX-LE 4), Waixiyan and Zusanli (ST 36) and other 38 caseswith combined therapies of acupuncture(of the same three points) and infrared radiation, achiev- ing cure rates of 68% and 71. 1 %, and total effective rates of 93.0% and 92.1% respectively.Comparison between the two groups in cure rate shows no statistical difference (P】0. 05). 展开更多
关键词 Infrapatellar fat pad STRAIN Acupuncture therapy Neixiyan-Waixiyan-Zusanli POINTS
下载PDF
Hypothenar fat pad flap vs conventional open release in primary carpal tunnel syndrome:A randomized controlled trial
7
作者 Thepparat Kanchanathepsak Wilarat Wairojanakul +3 位作者 Thitiporn Phakdepiboon Sorasak Suppaphol Ittirat Watcharananan Tulyapruek Tawonsawatruk 《World Journal of Orthopedics》 2017年第11期846-852,共7页
AIM To compared outcomes between the hypothenar fat pad flap(HTFPF) and conventional open carpal tunnel release(COR) in primary carpal tunnel syndrome(CTS). METHODS Forty-five patients(49 hands) were enrolled into the... AIM To compared outcomes between the hypothenar fat pad flap(HTFPF) and conventional open carpal tunnel release(COR) in primary carpal tunnel syndrome(CTS). METHODS Forty-five patients(49 hands) were enrolled into the study from January 2014 to March 2016, 8 patients were excluded. Randomization was conducted in 37 patients(41 hands) by computer generated(Block of four randomization) into COR and HTFPF group. Nerve conduction study(NCS) included distal sensory latency(DSL), distal motor latency(DML), sensory amplitude (S-amp), motor amplitude(M-amp) and sensory nerve conduction velocity(SCV) were examined at 6 and 12 wk after CTR. Levine score, grip and pinch strength, pain [visual analog scale(VAS)], 2-point discrimination(2-PD), Semmes-Weinstein monofilament test(SWM), Phalen test and Tinel's sign were evaluated in order to compare treatment outcomes.RESULTS The COR group, 19 patients(20 hands) mean age 50.4 years. The HTFPF group, 20 patients(21 hands) mean age 53.3 years. Finally 33 patients(36 hands) were analysed, 5 patients were loss follow-up, 17 hands in COR and 19 hands in HTFPF group. NCS revealed significant difference of DSL in HTFPF group at 6 wk(P < 0.05) compared with the COR group. S-amp was significant improved postoperatively in both groups(P < 0.05) but not significant difference between two groups. No significant difference of DML, M-amp and SCV postoperatively in both groups and between two groups. Levine score, pain(VAS), grip and pinch strength, 2-PD, SWM, Phalen test and Tinel's sign were improved postoperatively in both groups, but there was no significant difference between two groups.CONCLUSION There is no advantage outcome in primary CTS for having additional HTFPF procedure in CTR. COR is still the standard treatment. Nevertheless, improvement of DSL and S-amp could be observed at 6 wk postoperatively. 展开更多
关键词 Hypothenar fat pad FLAP Randomized controlled trial CARPAL TUNNEL RELEASE CARPAL TUNNEL syndrome NERVE conduction study
下载PDF
鼻尖以及IFP鼻尖穹窿部脂肪垫(interdomal fat pad简称:IFP)的解剖学以及临床研究进展
8
作者 王春虎 黄渭清 《中国生物美容》 2009年第4期51-54,共4页
鼻尖整形手术因患者人种、年龄、地区环境等诸多因素存在着较多差异。将“鼻部亚单位”等精细解剖学概念灵活地应用于鼻尖整形手术,可获得令人满意的美学效果。
关键词 鼻尖整形手术 解剖学 临床研究 脂肪垫 穹窿部 IFP fat pad
下载PDF
Recurrence of Lower Eyelid Fat Pads (Herniated Fat) after Blepharoplasty: An Analysis of Different Operative Techniques
9
作者 Riham Al Ashkar Sinan Alboudi Anwar Alhassanieh 《Modern Plastic Surgery》 2021年第3期63-69,共7页
<strong>Background:</strong> Aging changes to the lower eyelids and midface include all but not only these changes: pseudoherniated orbital fat, tear trough deformity, lid laxity, and dermatochalasis. Surg... <strong>Background:</strong> Aging changes to the lower eyelids and midface include all but not only these changes: pseudoherniated orbital fat, tear trough deformity, lid laxity, and dermatochalasis. Surgical repair often aims at treating redundant skin or orbital fat malposition with a lower eyelid blepharoplasty. In manipulating the inferior orbital fat pads, a surgeon has many options including excision, repositioning, or augmentation with synthetic dermal filler, autologous fat grafts, or acellular dermal allografts <a href="#ref1">[1]</a>. The aim of this study is to find the best approach in preventing fat herniation reccurnce in lower lid blepharoplasty. <strong>Methods: </strong>The patients in study were classified into three groups depending on the used surgical technique, to test the most effective technique associated with minimal rate of lower fat pad recurrence after surgery. Two of these techniques include a muscular flap suspension from the orbicularis oculae muscle. <strong>Results: </strong>The two surgical techniques that include orbicularis oculi muscle suspension are associated with no recurrence of lower herniated fat pads after blepharoplasty. <strong>Conclusions:</strong> The suspension of orbicularis oculi muscle has an important role in enhancing the lower orbital septum and prevents the recurrence of the lower herniated fat pads. 展开更多
关键词 Infraorbital fat Lower Lid Blepharoplasty Lower fat pads Orbicularis Oculi Muscle Suspension
下载PDF
能谱CT物质分离技术对膝关节骨性关节炎髌下脂肪垫物质的相关性研究
10
作者 张敏 谭辉 +3 位作者 樊秋菊 于楠 党珊 马春玲 《中国CT和MRI杂志》 2024年第1期162-163,共2页
目的利用能谱CT水脂分离技术对膝关节骨性关节炎患者进行髌下脂肪垫水脂定量分析的相关性研究,探讨髌骨下脂肪垫在骨性关节炎中的病理变化。方法对临床已进行WOMA疼痛评分的176膝患者进行分组,研究组A组为疼痛评分>40分的骨性关节炎... 目的利用能谱CT水脂分离技术对膝关节骨性关节炎患者进行髌下脂肪垫水脂定量分析的相关性研究,探讨髌骨下脂肪垫在骨性关节炎中的病理变化。方法对临床已进行WOMA疼痛评分的176膝患者进行分组,研究组A组为疼痛评分>40分的骨性关节炎患者98膝,对照组B组为疼痛评分<40分且无临床症状的78膝患者均行膝关节Gemstone Spectral Image(GSI)扫描,所得原始数据进行单能量60KeV及层厚1.25mm重建,利用GSI viewer软件进行分析,分别记录髌骨下内侧、中间及外侧脂肪垫的水基值及脂基值并取其平均值。对组间数据进行独立样本t检验,组内数据采进行皮尔逊相关性R检验。结果A、B两组患者年龄无统计学差异,P>0.05,58.62±8.13 vs 56.56±7.99岁。组内脂基值及水基值数据均呈明显的负相关,P<0.05,A组r=-0.93,B组r=-0.90;组间脂基值及水基值P<0.05,有统计学差异。结论膝关节骨性关节炎的患者其髌骨下脂肪垫的水含量(炎性水肿)增高,相对脂肪含量降低。 展开更多
关键词 能谱CT 物质分离技术 骨性关节炎 髌下脂肪垫
下载PDF
膝关节周围脂肪垫MRI表现与膝关节炎联系的研究进展
11
作者 王涛 张凤翔 杨金花 《影像技术》 CAS 2024年第2期75-80,共6页
膝关节骨性关节炎(knee osteoarthritis,KOA)是一种常见的膝关节退行性疾病。早期诊断膝关节骨关节炎对于采取及时干预和治疗具有重要意义。近年来,越来越多的研究表明,膝关节周围脂肪垫在膝关节骨关节炎的早期诊断中发挥着重要的角色... 膝关节骨性关节炎(knee osteoarthritis,KOA)是一种常见的膝关节退行性疾病。早期诊断膝关节骨关节炎对于采取及时干预和治疗具有重要意义。近年来,越来越多的研究表明,膝关节周围脂肪垫在膝关节骨关节炎的早期诊断中发挥着重要的角色。磁共振成像(MRI)因其无创、精确的优点,已成为一种常规的膝关节检查手段。该技术拥有出色的软组织分辨力,对于膝关节骨性关节炎患者在早期的骨质及周围软组织结构的细微改变,其展示出特有的优势,并且具有更高的敏感性和特异性,可以直接观察和量化膝关节周围脂肪垫的变化,为膝关节骨关节炎早期诊断开拓思路。 展开更多
关键词 膝关节周围脂肪垫 膝关节骨性关节炎 磁共振成像 早期诊断
下载PDF
应用颊脂垫联合邻近软组织瓣修复老年大型口腔上颌窦瘘
12
作者 徐泽东 孙国文 《口腔医学研究》 CAS CSCD 北大核心 2024年第4期321-324,共4页
目的:评价应用颊脂垫瓣联合邻近软组织瓣,同期修补由骨髓炎或肿瘤切除术中造成的老年大型口腔上颌窦瘘的临床效果。方法:收集南京大学医学院附属口腔医院口腔颌面外科2020年1月~2022年12月收治的术中并发大型(最大直径大于4 cm)口腔上... 目的:评价应用颊脂垫瓣联合邻近软组织瓣,同期修补由骨髓炎或肿瘤切除术中造成的老年大型口腔上颌窦瘘的临床效果。方法:收集南京大学医学院附属口腔医院口腔颌面外科2020年1月~2022年12月收治的术中并发大型(最大直径大于4 cm)口腔上颌窦瘘患者8例,患者年龄62~84岁。回顾性分析应用颊脂垫瓣联合颊侧推进瓣或腭黏膜瓣覆盖缺损,术后随访对疗效进行评估。结果:全部病例修复成功,未见软组织瓣坏死、穿孔、感染及上颌窦炎鼻窦炎,随访3个月颌面部基本对称,经张口训练后,张口度恢复正常。结论:颊脂垫瓣联合邻近软组织瓣是方便可靠的修复老年大型口腔上颌窦瘘方法,值得临床推广。 展开更多
关键词 老年 口腔上颌窦瘘 颊脂垫 邻近软组织瓣
下载PDF
髌腱-股骨外侧髁摩擦综合征MRI表现及分析
13
作者 张懿娜 周岱磐 +2 位作者 孙道东 戴维龙 朱俊琛 《影像诊断与介入放射学》 2024年第2期128-133,共6页
目的探讨髌腱-股骨外侧髁摩擦综合征(PT-LFCFS)的MRI表现与相关参数。方法研究对象60例,收集临床和MRI均诊断为PT-LFCFS的患者30例作为研究组,收集同期无膝关节MRI髌下脂肪垫损伤者30例作为对照组。对比观察研究组与对照组的MRI征象,测... 目的探讨髌腱-股骨外侧髁摩擦综合征(PT-LFCFS)的MRI表现与相关参数。方法研究对象60例,收集临床和MRI均诊断为PT-LFCFS的患者30例作为研究组,收集同期无膝关节MRI髌下脂肪垫损伤者30例作为对照组。对比观察研究组与对照组的MRI征象,测量Install-Salvati指数(ISR)、髌腱-股骨外侧髁滑车关节面(PL-T)最短距离、胫骨结节-股骨滑车沟(TT-TG)距离、股骨外侧髁角(LFCA)、股骨外侧髁长度(LTL)和股骨外侧髁高度(LTH),统计两组病例髌腱炎、髌骨外侧支持带损伤、髌股关节炎、胫股关节炎及股四头肌腱炎的发病率,并对两组结果进行比较。结果PT-LFCFS组在质子密度加权成像(PDWI)脂肪抑制序列见髌下脂肪垫外上部局限性水肿,对照组无髌下脂肪垫水肿表现。PT-LFCFS组PL-T、LFCA小于对照组[(0.26±0.08)cm,(0.76±0.11)cm,t=20.913,P<0.001;(82.99±4.94)°,(100.52±5.07)°,t=13.565,P<0.001],ISR、TT-TG、LTL、LTH大于对照组[(1.41±0.12),(1.01±0.08),t=-14.649,P<0.001;(1.14±0.37)cm,(0.69±0.21)cm,t=-5.899,P<0.001;(2.19±0.21)cm,(1.98±0.12)cm,t=-4.784,P<0.001;(0.80±0.13)cm,(0.68±0.11)cm,t=-4.003,P<0.001]。PT-LFCFS组在髌股关节炎、髌骨外侧支持带损伤的发病率高于对照组[25(83.3%),2(6.7%),x^(2)=32.593,P<0.001;27(90%),1(3.3%),x^(2)=41.853,P<0.001]。两组间髌腱炎、胫股关节炎及股四头肌腱炎的发病率差异无统计学意义(P>0.05)。结论PT-LFCFS的MRI特征性表现是髌下脂肪垫外上部局限性水肿,PL-T、LFCA减小,ISR、TT-TG、LTL、LTH增大。PT-LFCFS患者中,髌股关节炎、髌骨外侧支持带损伤的发病率较高。 展开更多
关键词 髌腱-股骨外侧髁摩擦综合征 髌下脂肪垫 磁共振成像
下载PDF
液相色谱-质谱技术在骨关节炎局部组织样本检测中的应用进展
14
作者 刘德仁 廖太阳 +1 位作者 吴鹏 茆军 《中国医药导报》 CAS 2024年第10期186-188,共3页
骨关节炎(OA)历来被认为是一种慢性退行性疾病,关节内多个组织的分解代谢紊乱与OA的发生、发展密切相关。液相色谱-质谱(LC-MS)技术能检测OA中特定的代谢物和相关代谢途径,揭示OA潜在的病理和生理代谢过程。本文对近几年内利用LC-MS技... 骨关节炎(OA)历来被认为是一种慢性退行性疾病,关节内多个组织的分解代谢紊乱与OA的发生、发展密切相关。液相色谱-质谱(LC-MS)技术能检测OA中特定的代谢物和相关代谢途径,揭示OA潜在的病理和生理代谢过程。本文对近几年内利用LC-MS技术检测OA中关节软骨、滑膜和脂肪垫样本的代谢结果进行讨论并总结,综述了OA局部组织样本经LC-MS技术检测出的差异代谢物和代谢途径,为LC-MS技术鉴定OA进展相关生物标志物提供理论依据。 展开更多
关键词 骨关节炎 液相色谱-质谱 关节软骨 滑膜 脂肪垫
下载PDF
膝关节骨关节炎病人结构改变与股四头肌脂肪垫和股前脂肪垫改变的相关性研究
15
作者 郑丽楠 刘学 《临床外科杂志》 2024年第5期529-531,共3页
目的探讨膝关节骨关节炎病人结构改变与股四头肌脂肪垫(QFP)和股前脂肪垫(PFP)影像学改变之间的关系。方法2020年6月~2022年6月收治的膝关节骨关节炎病人100例,共150个膝关节,将150个膝关节分为两组,非膝关节放射学骨性关节炎(ROA)组和... 目的探讨膝关节骨关节炎病人结构改变与股四头肌脂肪垫(QFP)和股前脂肪垫(PFP)影像学改变之间的关系。方法2020年6月~2022年6月收治的膝关节骨关节炎病人100例,共150个膝关节,将150个膝关节分为两组,非膝关节放射学骨性关节炎(ROA)组和ROA组,比较两组的QFP、PFP各参数,分析各参数与KLG分级、Hoffa滑膜炎、渗出性滑膜炎的相关性。结果ROA组QFP头尾径长于非ROA组,QFP高信号、PFP髌股高信号例数多于非ROA组,QFP肿块效应例数少于非ROA组,PFP最大厚度低于非ROA组;QFP高信号、PFP髌骨高信号与KLG分级呈正相关(r=0.271、0.399),PFP最大厚度与KLG分级呈负相关(r=-0.418);QFP高信号与Hoffa滑膜炎呈正相关(r=0.330),QFP肿块效应、PFP最大厚度与Hoffa滑膜炎呈负相关(r=-0.291、-0.441);PFP最大厚度与渗出性滑膜炎呈负相关(r=-0.561)。PFP髌骨高信号与不同部位软骨缺损均呈正相关(r=0.320、0.418、0.358、0.410、0.291),QFP肿块效应、PFP最大厚度与不同部位软骨缺损均呈负相关(r=-0.358、--0.287、-0.287、-0.287、-0.170、-0.399、-0.438、-0.498、-0.457、-0.350),QFP前后径与胫骨内侧软骨缺损呈负相关(r=-0.260)。结论QFP和PFP影像学改变与膝关节骨关节炎病人KLG分级、滑膜炎改变、关节软骨缺损、软骨下骨髓病变有相关性,在膝关节骨关节炎的发生与发展中占有重要的位置。 展开更多
关键词 膝关节骨关节炎 结构改变 股四头肌脂肪垫 股前脂肪垫 影像学改变 相关性
下载PDF
限时饮食对高脂饮食诱导肥胖大鼠髌下脂肪垫的影响及作用机制
16
作者 丁煜堃 祝翠玲 张晓东 《中国组织工程研究》 CAS 北大核心 2024年第34期5425-5431,共7页
背景:超重或肥胖是膝骨关节炎最主要的危险因素。限时饮食在预防超重或肥胖方面显示出明显的效果。髌下脂肪垫是膝关节的重要组成部分,其是否受到限时饮食的影响,从而影响膝骨关节炎目前仍不清楚。目的:利用高脂饮食诱导的大鼠模型,探... 背景:超重或肥胖是膝骨关节炎最主要的危险因素。限时饮食在预防超重或肥胖方面显示出明显的效果。髌下脂肪垫是膝关节的重要组成部分,其是否受到限时饮食的影响,从而影响膝骨关节炎目前仍不清楚。目的:利用高脂饮食诱导的大鼠模型,探究限时饮食减重对髌下脂肪垫的影响,为肥胖相关性膝骨关节炎的早期预防和治疗提供证据。方法:将15只雄性SD大鼠随机分为3组,每组5只。正常对照组大鼠可24 h任意进食,饲喂普通饲料(12%脂肪);高脂饮食组大鼠可24 h任意进食,饲喂高脂饮食(45%脂肪);高脂饮食限时进食组大鼠只在9:00(光照后2 h)至17:00(黑暗前2 h)饲喂高脂饮食。饲养8周后,m Dixon-Quant序列用于评估髌下脂肪垫和右侧腹股沟区皮下脂肪组织的质子密度脂肪分数;ELISA用于定量血清中脂肪因子水平;天狼猩红染色评估髌下脂肪垫纤维化变化;免疫组织化学染色检测解偶联蛋白1在髌下脂肪垫和右侧腹股沟区皮下脂肪组织中的表达以及瘦素、脂联素和肿瘤坏死因子α在髌下脂肪垫中的表达。结果与结论:饲养8周后,(1)与高脂饮食组相比,正常对照组(P=0.036)和高脂饮食限时进食组(P=0.003)的大鼠体质量明显减轻;(2)高脂饮食组大鼠髌下脂肪垫的质子密度脂肪分数明显大于正常对照组(P <0.001)和高脂饮食限时进食组(P=0.004),而3组间皮下脂肪组织的质子密度脂肪分数差异无显著性意义;(3)高脂饮食组的大鼠血清瘦素水平明显高于正常对照组(P=0.030)和高脂饮食限时进食组(P=0.018);(4)与高脂饮食组相比,正常对照组(P <0.001)和高脂饮食限时进食组(P=0.003)以天狼猩红染色为特征的髌下脂肪垫纤维化程度明显降低;(5)高脂饮食组的髌下脂肪垫中瘦素相对表达明显高于正常对照组(P <0.001)和高脂饮食限时进食组(P <0.001);高脂饮食组的髌下脂肪垫中脂联素相对表达明显低于正常对照组(P=0.004)和高脂饮食限时进食组(P=0.048);然而,3组髌下脂肪垫和皮下脂肪组织中均无解偶联蛋白1阳性表达以及髌下脂肪垫中均无肿瘤坏死因子α阳性表达;(6)上述结果表明,限时饮食可以延缓高脂饮食诱导的大鼠髌下脂肪垫的纤维化,降低髌下脂肪垫的质子密度脂肪分数值,并影响血清和髌下脂肪垫中脂肪因子的水平,限时饮食可能是治疗和预防肥胖相关膝骨关节炎的一种简单有效的方法。 展开更多
关键词 限时饮食 髌下脂肪垫 纤维化 肥胖 膝骨关节炎 减重 脂肪因子 动物实验
下载PDF
经睑袋入路提升颧脂肪垫在中面部年轻化治疗中的应用
17
作者 王共礼 张伟 +1 位作者 滕俊杰 何金峻 《中国美容医学》 CAS 2024年第2期28-30,共3页
目的:观察经睑袋入路,通过中面部软组织提升改善睑袋、泪沟、鼻唇沟、颧颊沟及颧区下垂的临床效果。方法:在常规睑袋整形术中,沿眶下缘向下剥离5~10 mm,分别在眶下缘内、中、外三点提升固定颧脂肪垫,外眦处行“铆定悬吊”,填充泪沟凹陷... 目的:观察经睑袋入路,通过中面部软组织提升改善睑袋、泪沟、鼻唇沟、颧颊沟及颧区下垂的临床效果。方法:在常规睑袋整形术中,沿眶下缘向下剥离5~10 mm,分别在眶下缘内、中、外三点提升固定颧脂肪垫,外眦处行“铆定悬吊”,填充泪沟凹陷的同时,达到中面部的提升。结果:2019年1月-2022年6月在笔者医院行睑袋术的1163例病例中,增加经睑袋入路提升颧脂肪垫操作,术后所有就医者中面部软组织上提明显,泪沟、鼻唇沟、颧颊沟及颧区下垂等均明显改善,满意率达100%。结论:经睑袋入路,通过中面部软组织提升改善睑袋、泪沟、鼻唇沟、颧颊沟及颧区下垂效果显著,值得在临床推广应用。 展开更多
关键词 睑袋 泪沟 颧脂肪垫 中面部提升
下载PDF
改良带蒂心包前脂肪垫预防高危患者肺叶切除术后支气管胸膜瘘的临床研究
18
作者 罗倩 宋永祥 《遵义医科大学学报》 2024年第4期338-343,共6页
目的 探讨使用改良带蒂心包前脂肪垫进行支气管残端包埋在高危患者肺叶切除术后预防支气管胸膜瘘的临床疗效,为临床支气管胸膜瘘的预防提供可行的方法及依据。方法 收集我院胸外科2017年1月—2019年3月行肺叶切除术且具有支气管胸膜瘘... 目的 探讨使用改良带蒂心包前脂肪垫进行支气管残端包埋在高危患者肺叶切除术后预防支气管胸膜瘘的临床疗效,为临床支气管胸膜瘘的预防提供可行的方法及依据。方法 收集我院胸外科2017年1月—2019年3月行肺叶切除术且具有支气管胸膜瘘高危因素患者的临床资料,术中支气管残端未做特殊处理,为对照组;收集2019年3月—2021年11月行肺叶切除术且具有支气管胸膜瘘高危因素患者的临床资料,术中进行改良带蒂心包前脂肪垫包埋支气管残端,为试验组。两组进行1∶1倾向性评分匹配,术后进行随访,统计分析两组患者在支气管胸膜瘘发生率及发生时间、死亡率、手术时间、术中出血量、术后带管时间、术后其他并发症的差异。结果 本研究纳入试验组105例,对照组215例,均顺利完成肺叶切除术,倾向性评分匹配后得到78对。对照组共发生支气管胸膜瘘5例,发生率为6.41%,试验组无支气管胸膜瘘发生,差异有明显统计学意义(P=0.028),两组均无死亡病例;手术时间及出血量两组之间差异无统计学意义(z=-1.774,P=0.076;z=-1.404,P=0.16);试验组带管时间明显少于对照组(z=-4.725,P<0.001);试验组发生包裹性液气胸、肺持续漏气、再次置管较对照组明显减少(χ^(2)=4.792,P=0.029;χ^(2)=5.347,P=0.021;χ^(2)=5.778,P=0.016)。结论 改良带蒂心包前脂肪垫覆盖支气管残端在预防高危患者支气管胸膜瘘方面具有明显的优势,可降低高危患者术后支气管胸膜瘘发生率,减少术后带管时间及术后并发症。 展开更多
关键词 改良 带蒂心包前脂肪垫 支气管胸膜瘘 肺叶切除术 高危因素
下载PDF
内热针治疗髌下脂肪垫炎30例临床观察
19
作者 张萍 王月 唐越 《中国民族民间医药》 2023年第19期85-87,112,共4页
目的:研究内热针疗法治疗髌下脂肪垫炎患者的临床疗效。方法:选取就诊于我科的60例髌下脂肪垫炎患者,随机分为2组,对照组给予口服药物治疗,观察组给予内热针治疗,两组治疗结束后分别在2周、3个月进行疗效判定。结果:治疗后两组在2周、3... 目的:研究内热针疗法治疗髌下脂肪垫炎患者的临床疗效。方法:选取就诊于我科的60例髌下脂肪垫炎患者,随机分为2组,对照组给予口服药物治疗,观察组给予内热针治疗,两组治疗结束后分别在2周、3个月进行疗效判定。结果:治疗后两组在2周、3个月VAS评分均具有显著的下降,Lysholm评分有显著的提高,两组比较差别均有统计学意义(P<0.05)。两组有效率比较,对照组有效率83.3%,观察组有效率为90%,观察组有效率明显高于对照组。结论:通过内热针治疗对于髌下脂肪垫炎患者的临床症状缓解明显,尤其对膝关节疼痛和关节功能的改善方面疗效显著,治疗周期短,患者易于接受,值得临床推广。 展开更多
关键词 髌下脂肪垫炎 内热针 双氯酚酸钠胶囊
下载PDF
超声造影在膝骨关节炎患者髌下脂肪垫血流灌注中的临床应用探讨 被引量:1
20
作者 王佩璐 肖迎聪 +1 位作者 王育飞 卢璐 《医学影像学杂志》 2023年第1期96-99,共4页
目的 探讨超声造影技术在膝骨关节炎(KOA)患者髌下脂肪垫血流灌注情况的临床应用优势与价值。方法选取因膝骨关节炎就诊的患者46例,同时选取12例自愿行肌骨超声及超声造影的健康者为对照组。膝骨关节炎组根据Kellgren-Lawrence分级分为... 目的 探讨超声造影技术在膝骨关节炎(KOA)患者髌下脂肪垫血流灌注情况的临床应用优势与价值。方法选取因膝骨关节炎就诊的患者46例,同时选取12例自愿行肌骨超声及超声造影的健康者为对照组。膝骨关节炎组根据Kellgren-Lawrence分级分为3个亚组。参与者均行常规膝关节超声检查及髌下脂肪垫超声造影检查。观察髌下脂肪垫血流信号显示情况,分析超声造影下时间-强度曲线的最大强度及曲线下面积。结果 膝骨关节炎组髌下脂肪垫彩色多普勒显示率100%,对照组显示率83.33%,两组彩色多普勒显示率差异有统计学意义(P<0.05)。超声造影在两组均可见增强。膝骨关节炎K-L分级2级、3级组最大强度均高于对照组(P<0.01)。不同分级之间最大强度依次递增,除K-L1级、3级组之间有统计学意义外,其余组间差异无统计学意义(P>0.05)。膝骨关节炎各K-L分级组曲线下面积均高于对照组,且差异有统计学意义(P<0.05),KOA组不同分级之间曲线下面积依次递增,但组间差异无统计学意义(P>0.05)。结论 超声造影能够显示髌下脂肪垫的血流灌注情况。膝骨关节炎患者髌下脂肪垫的血流灌注强度增高,提示膝骨关节炎患者可能也存在髌下脂肪垫炎症,为该疾病诊断及预后提出新的观测点和影像学证据。 展开更多
关键词 超声造影 膝骨关节炎 髌下脂肪垫 血流灌注
下载PDF
上一页 1 2 18 下一页 到第
使用帮助 返回顶部