Objective:To explore the effect of early rehabilitation training on the serum NGF, NSE, BDNF, and motor function in patients with acute cerebral infarction (ACI).Methods: A total of 150 patients with ACI who were admi...Objective:To explore the effect of early rehabilitation training on the serum NGF, NSE, BDNF, and motor function in patients with acute cerebral infarction (ACI).Methods: A total of 150 patients with ACI who were admitted in our hospital from October, 2015 to October, 2016 were included in the study and randomized into the observation group and the control group. The patients in the two groups were given anti-coagulation, anti-platelet aggregation, cerebral circulation improving, and brain cell activators. The patients in the control group were given routine neurological nursing, while the patients in the observation group were given early comprehensive rehabilitation training on the basis of stable vital signs and no disease progression within 48 h. The morning fasting peripheral venous blood before treatment, 2 and 4 weeks after treatment in the two groups was collected. The serum NGF, NSE, BDNF, IL-6, hs-CRP, and TNF-α were detected. The activities of daily living and motor function before treatment, 2 and 4 weeks after treatment in the two groups were evaluated.Results:IL-6, hs-CRP, and TNF-α levels 2 and 4 weeks after treatment in the observation group were significantly lower than those in the control group (P<0.05). NGF and BDNF levels 2 and 4 weeks after treatment in the observation group were significantly higher than those in the control group (P<0.05), while NSE level was significantly lower than that in the control group (P<0.05). MBI and FMA scores 2 and 4 weeks after treatment in the observation group were significantly higher than those in the control group (P<0.05).Conclusions: The early rehabilitation training can effectively reduce the inflammatory reaction of nervous system in patients with ACI, regulate NGF, BDNF, and NSE levels, and play the cerebral function remodeling in order to promote the neural function recovery, and improve the motor function.展开更多
目的探讨亲情化护理联合多模块康复护理在急性脑梗死偏瘫患者中的应用效果。方法随机选取2021年3月—2023年3月于福建中医药大学附属康复医院接受治疗的急性脑梗死偏瘫患者180例作为研究对象。参照随机数表法将其分为对照组、联合组,各9...目的探讨亲情化护理联合多模块康复护理在急性脑梗死偏瘫患者中的应用效果。方法随机选取2021年3月—2023年3月于福建中医药大学附属康复医院接受治疗的急性脑梗死偏瘫患者180例作为研究对象。参照随机数表法将其分为对照组、联合组,各90例。对照组患者接受常规护理,联合组患者接受亲情化护理联合多模块康复护理。对比两组患者干预前后运动功能、日常生活能力、生活质量。结果入院即刻,两组患者的上肢及手、下肢运动功能评分,巴氏(Barthel)量表平均得分,脑卒中专用生活质量量表(Stroke Specific Quality of Life Scale,SS-QOL)评分对比,差异无统计学意义(P均>0.05)。出院当日,联合组患者上肢及手、下肢运动功能评分高于对照组,差异有统计学意义(P均<0.05);联合组Barthel量表平均得分(88.74±10.26)分优于对照组,差异有统计学意义(t=4.188,P<0.05);联合组SS-QOL评分(214.67±20.09)分高于对照组(t=6.531,P<0.05)。结论亲情化护理联合多模块康复护理应用于急性脑梗死偏瘫患者中,有助于优化患者的肢体功能、增强日常生活能力,最终提升生活质量,是一种理想的联合护理模式。展开更多
目的探究急性大面积脑梗死患者开展开颅去大骨瓣减压联合康复治疗的临床效果。方法选择2021年2月—2023年2月高密市人民医院收治的46例急性大面积脑梗死患者为研究对象,按随机数表法分为研究组和对照组,各23例。所有患者全部开展开颅去...目的探究急性大面积脑梗死患者开展开颅去大骨瓣减压联合康复治疗的临床效果。方法选择2021年2月—2023年2月高密市人民医院收治的46例急性大面积脑梗死患者为研究对象,按随机数表法分为研究组和对照组,各23例。所有患者全部开展开颅去大骨瓣减压术治疗,对照组予以基础康复治疗,研究组予以综合康复治疗。比较两组患肢关节改良Ashworth分级(Modified Ashworth Scale,MAS)、美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)、Fugl-Meyer肢体运动功能量表(Fugl-Meyer Assessment,FMA)、Barthel指数(Barthel Index,BI)影响。结果治疗前,两组MAS评分、NIHSS评分、FMA评分、BI指数比较,差异无统计学意义(P均>0.05)。治疗后,研究组NIHSS评分(15.26±2.21)分、MAS评分(1.18±0.42)分,低于对照组的(17.21±2.70)分、(1.96±0.37)分,差异有统计学意义(t=2.680、6.683,P均<0.05)。治疗后,研究组FMA评分(59.90±8.23)分、BI指数(81.96±10.59)分,高于对照组的(55.50±3.69)分、(72.25±13.36)分,差异有统计学意义(t=2.340、2.708,P均<0.05)。结论急性大面积脑梗死患者开展开颅去大骨瓣减压联合综合康复治疗的效果显著,可改善神经受损情况,提升肢体功能、自理能力。展开更多
文摘Objective:To explore the effect of early rehabilitation training on the serum NGF, NSE, BDNF, and motor function in patients with acute cerebral infarction (ACI).Methods: A total of 150 patients with ACI who were admitted in our hospital from October, 2015 to October, 2016 were included in the study and randomized into the observation group and the control group. The patients in the two groups were given anti-coagulation, anti-platelet aggregation, cerebral circulation improving, and brain cell activators. The patients in the control group were given routine neurological nursing, while the patients in the observation group were given early comprehensive rehabilitation training on the basis of stable vital signs and no disease progression within 48 h. The morning fasting peripheral venous blood before treatment, 2 and 4 weeks after treatment in the two groups was collected. The serum NGF, NSE, BDNF, IL-6, hs-CRP, and TNF-α were detected. The activities of daily living and motor function before treatment, 2 and 4 weeks after treatment in the two groups were evaluated.Results:IL-6, hs-CRP, and TNF-α levels 2 and 4 weeks after treatment in the observation group were significantly lower than those in the control group (P<0.05). NGF and BDNF levels 2 and 4 weeks after treatment in the observation group were significantly higher than those in the control group (P<0.05), while NSE level was significantly lower than that in the control group (P<0.05). MBI and FMA scores 2 and 4 weeks after treatment in the observation group were significantly higher than those in the control group (P<0.05).Conclusions: The early rehabilitation training can effectively reduce the inflammatory reaction of nervous system in patients with ACI, regulate NGF, BDNF, and NSE levels, and play the cerebral function remodeling in order to promote the neural function recovery, and improve the motor function.
文摘目的探讨亲情化护理联合多模块康复护理在急性脑梗死偏瘫患者中的应用效果。方法随机选取2021年3月—2023年3月于福建中医药大学附属康复医院接受治疗的急性脑梗死偏瘫患者180例作为研究对象。参照随机数表法将其分为对照组、联合组,各90例。对照组患者接受常规护理,联合组患者接受亲情化护理联合多模块康复护理。对比两组患者干预前后运动功能、日常生活能力、生活质量。结果入院即刻,两组患者的上肢及手、下肢运动功能评分,巴氏(Barthel)量表平均得分,脑卒中专用生活质量量表(Stroke Specific Quality of Life Scale,SS-QOL)评分对比,差异无统计学意义(P均>0.05)。出院当日,联合组患者上肢及手、下肢运动功能评分高于对照组,差异有统计学意义(P均<0.05);联合组Barthel量表平均得分(88.74±10.26)分优于对照组,差异有统计学意义(t=4.188,P<0.05);联合组SS-QOL评分(214.67±20.09)分高于对照组(t=6.531,P<0.05)。结论亲情化护理联合多模块康复护理应用于急性脑梗死偏瘫患者中,有助于优化患者的肢体功能、增强日常生活能力,最终提升生活质量,是一种理想的联合护理模式。
文摘目的探究急性大面积脑梗死患者开展开颅去大骨瓣减压联合康复治疗的临床效果。方法选择2021年2月—2023年2月高密市人民医院收治的46例急性大面积脑梗死患者为研究对象,按随机数表法分为研究组和对照组,各23例。所有患者全部开展开颅去大骨瓣减压术治疗,对照组予以基础康复治疗,研究组予以综合康复治疗。比较两组患肢关节改良Ashworth分级(Modified Ashworth Scale,MAS)、美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)、Fugl-Meyer肢体运动功能量表(Fugl-Meyer Assessment,FMA)、Barthel指数(Barthel Index,BI)影响。结果治疗前,两组MAS评分、NIHSS评分、FMA评分、BI指数比较,差异无统计学意义(P均>0.05)。治疗后,研究组NIHSS评分(15.26±2.21)分、MAS评分(1.18±0.42)分,低于对照组的(17.21±2.70)分、(1.96±0.37)分,差异有统计学意义(t=2.680、6.683,P均<0.05)。治疗后,研究组FMA评分(59.90±8.23)分、BI指数(81.96±10.59)分,高于对照组的(55.50±3.69)分、(72.25±13.36)分,差异有统计学意义(t=2.340、2.708,P均<0.05)。结论急性大面积脑梗死患者开展开颅去大骨瓣减压联合综合康复治疗的效果显著,可改善神经受损情况,提升肢体功能、自理能力。