This case study explores the diagnosis and treatment of a 51-year-old female with exacerbated anxiety and depressive symptoms, which worsened prior to menstruation. Initial concerns involved the maximum dosage of psyc...This case study explores the diagnosis and treatment of a 51-year-old female with exacerbated anxiety and depressive symptoms, which worsened prior to menstruation. Initial concerns involved the maximum dosage of psychiatric medications with persistent major depressive disorder and suicidal ideations. This led to a referral for a comprehensive evaluation to assess potential underlying medical conditions. The evaluation revealed multiple contributing factors, including hormonal imbalances, hypothyroidism, and vitamin deficiencies. This case highlights the importance of a thorough diagnostic approach to identify and address underlying conditions that may exacerbate mental health issues.展开更多
Oestrogens are not exclusive to the female gender but occur in moderate circulating levels of 25-70 pg ml^-1 in men, compared to 44- 153 pg ml^-1 in women. Arising from aromatisation of testosterone （T）, oestrogen i...Oestrogens are not exclusive to the female gender but occur in moderate circulating levels of 25-70 pg ml^-1 in men, compared to 44- 153 pg ml^-1 in women. Arising from aromatisation of testosterone （T）, oestrogen is considered to have many opposing physiological functions and the progressive T decline in the aging male is associated with relative and/or absolute increase in serum oestradiol （E2）. Sexual disinterest and erectile dysfunction （ED） in the elderly may well be due to pathophysiological E2-T imbalance; the altered hormonal ratio may also explain the higher incidence of ED in hyperestrogenism or following exposure to environmental/plant oestrogens.展开更多
文摘This case study explores the diagnosis and treatment of a 51-year-old female with exacerbated anxiety and depressive symptoms, which worsened prior to menstruation. Initial concerns involved the maximum dosage of psychiatric medications with persistent major depressive disorder and suicidal ideations. This led to a referral for a comprehensive evaluation to assess potential underlying medical conditions. The evaluation revealed multiple contributing factors, including hormonal imbalances, hypothyroidism, and vitamin deficiencies. This case highlights the importance of a thorough diagnostic approach to identify and address underlying conditions that may exacerbate mental health issues.
文摘Oestrogens are not exclusive to the female gender but occur in moderate circulating levels of 25-70 pg ml^-1 in men, compared to 44- 153 pg ml^-1 in women. Arising from aromatisation of testosterone （T）, oestrogen is considered to have many opposing physiological functions and the progressive T decline in the aging male is associated with relative and/or absolute increase in serum oestradiol （E2）. Sexual disinterest and erectile dysfunction （ED） in the elderly may well be due to pathophysiological E2-T imbalance; the altered hormonal ratio may also explain the higher incidence of ED in hyperestrogenism or following exposure to environmental/plant oestrogens.
