A brief review of Huang–Rhys theory and Albrechtos theory is provided,and their connection and applications are discussed.The former is a first order perturbative theory on optical transitions intended for applicatio...A brief review of Huang–Rhys theory and Albrechtos theory is provided,and their connection and applications are discussed.The former is a first order perturbative theory on optical transitions intended for applications such as absorption and emission involving localized defect or impurity centers,emphasizing lattice relaxation or mixing of vibrational states due to electron–phonon coupling.The coupling strength is described by the Huang–Rhys factor.The latter theory is a second order perturbative theory on optical transitions intended for Raman scattering,and can in-principle include electron–phonon coupling in both electronic states and vibrational states.These two theories can potentially be connected through the common effect of lattice relaxation – non-orthonormal vibrational states associated with different electronic states.Because of this perceived connection,the latter theory is often used to explain resonant Raman scattering of LO phonons in bulk semiconductors and further used to describe the size dependence of electron–phonon coupling or Huang–Rhys factor in semiconductor nanostructures.Specifically,the A term in Albrechtos theory is often invoked to describe the multi-LO-phonon resonant Raman peaks in both bulk and nanostructured semiconductors in the literature,due to the misconception that a free-exciton could have a strong lattice relaxation.Without lattice relaxation,the A term will give rise to Rayleigh or elastic scattering.Lattice relaxation is only significant for highly localized defect or impurity states,and should be practically zero for either single particle states or free exciton states in a bulk semiconductor or for confined states in a semiconductor nanostructure that is not extremely small.展开更多
Objective To analyze the effects of Dan Huang Ming Mu Recipe(DHMMR)(a pharmaceutical preparation from herbs and having the function of replenishing vital essence,removing heat,promoting blood circulation and excreting...Objective To analyze the effects of Dan Huang Ming Mu Recipe(DHMMR)(a pharmaceutical preparation from herbs and having the function of replenishing vital essence,removing heat,promoting blood circulation and excreting pathogenic water) on diabetic retinopathy(DR) after retinal laser photocoagulation through regulating the expression of vascular endothelial growth factor(VEGF) and pigment epithelium-derived factor(PEDF).Methods Forty male Brown Norway(BN) rats were randomly divided into blank group(group A,10 BN rats) and model group(30 BN rats).DR models were induced by 40 mg/kg streptozotocin(STZ) and the body weight and blood glucose of rats were monitored.After 12-week injection,fluorescein fundus angiography(FFA) and histopathological examination were detected to confirm the successful establishment of DR models.Subsequently,the right eyes of model group rats were conducted retinal laser photocoagulation with the left eyes having no retinal laser photocoagulation and rats of the model group were randomly divided into group B(the model control group),group C(the positive control group),and group D(the DHMMR group),with 10 rats in each group.Rats of the group A and the group B were given vehicle,and the group C were given calcium dobesilate suspension by gavage,and the group D were given DHMMR by gavage.After 4-week gavage,FFA was carried out to observe the fundus microvascular change.Then,the rats were sacrificed to do histopathological examinations and the serum levels of P-selectin,cAMP,cGMP,and the relative expression of the protein of VEGF and PEDF in retina were detected.Results After 12-week STZ injection,the blood glucose of the model group were pronouncedly higher than the blank group(P < 0.01).Fundus micro-hemangioma changes were observed in the rats of the model group through FFA,and the rats of the blank group did not see any changes.The pictures of HE staining showed that the retinal structure of the model group was more disordered than the blank group.After 4-week gavage,treatments with DHMMR showed dramatic reduction of serum levels of Pselectin,cAMP and cGMP compared with the group B(P < 0.01).FFA and histopathological examinations of DHMMR-treated rats revealed significantly suppression of retinal edema,fundus microvascular destruction and retinal destruction distinguishing from the group B.And the relative expression of VEGF protein of the group D and the group A was markedly lower than that of the group B(P < 0.01).The relative expression of PEDF protein of the group D and the group A was dramatically higher than that of the group B to the contrary(P < 0.01).Conclusions DHMMR demonstrates pronounced suppressive effects on the progression of DR after retinal laser photocoagulation,through down-regulating VEGF and upregulating PEDF.展开更多
Taking Huang-Huai Plain as an example,evaluation index system is established from four aspects,including the resources condition,the social and economic condition,the agricultural science and technology condition,and ...Taking Huang-Huai Plain as an example,evaluation index system is established from four aspects,including the resources condition,the social and economic condition,the agricultural science and technology condition,and the disaster resistant and sustainable production condition.Correlation coefficient method and expert consultation method are used to determine the weight of evaluation index.After the standardization of extreme value,weighted sum method and multiple regression method are adopted to evaluate the influencing factors of agricultural land productivity in Huang-Huai Plain,China.Evaluation result shows that agricultural science and technology condition has a lower contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Resources condition has a higher contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Both the social and economic condition and the disaster control and sustainable production condition show relatively small contribution rate to the productivity of Huang-Huai Plain.It can be concluded that the main factors affecting the productivity of Huang-Huai Plain are the backward agricultural science and technology level,the poor farmland quality and the farmland infrastructure.Based on this,relevant suggestions are put forward to improve the farmland productivity of Huang-Huai Plain.展开更多
Epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI)plays an important role in cancer therapy.However,EGFR is highly expressed in the skin and gives rise to one of the most concerning issues for the EG...Epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI)plays an important role in cancer therapy.However,EGFR is highly expressed in the skin and gives rise to one of the most concerning issues for the EGFR-TKI treatment,namely skin toxicity.Antibiotics and corticosteroids are usually used to treat the EGFR inhibitor-associated skin rash,with prominent side effects over long-time use.Pien Tze Huang(PZH)Unguentum Compositum is a traditional product for external application which is made of traditional Chinese medicine and oil base.Herein,we reported the case of a 50-year-old man who presented with skin rash on the face,head,and back induced by an EGFR-TKI named erlotinib.By using PZH Unguentum Compositum,we observed that the skin rash was mitigated and eventually disappeared.This case report suggests that PZH Unguentum Compositum may be an effective therapy in treating skin rash caused by EGFR-TKI with fewer side effects.展开更多
We develop in this paper the theory of multiphonon radiative transition so that someimportant physical quantities that describe effect s of lattice relaxation in electron transitions,for example, Huang--Rhys parameter...We develop in this paper the theory of multiphonon radiative transition so that someimportant physical quantities that describe effect s of lattice relaxation in electron transitions,for example, Huang--Rhys parameters, lattice relaxation energies and Stokes shifts, becomecomputable directly. The calculated results of the se physical quantities for alexandrite agreewith experimental data very well. Besides, we deduce expressions of intensity distributionand integrated intensity of a multiphonon sideband in non--Condon approximation. The cal-culated values of integrated intensities are obviously better than the intensity fitting resultsof previous work. From these calculated values we can also acquire a quantitative under-standing of the errors of Condon approximation.展开更多
实现粮食的持续稳定增长是保障区域粮食安全的关键。分解各因素对粮食生产的作用及影响强度,识别其主导因素,对提升粮食产量具有积极意义。该文运用对数平均迪氏分解方法(logarithmic mean weigh division index method,LMDI)建立因素...实现粮食的持续稳定增长是保障区域粮食安全的关键。分解各因素对粮食生产的作用及影响强度,识别其主导因素,对提升粮食产量具有积极意义。该文运用对数平均迪氏分解方法(logarithmic mean weigh division index method,LMDI)建立因素分解模型,定量评价并对比分析1980-2010年间黄淮海地区县域粮食生产变动的区域因素。结果表明,1)1980-2010年间,黄淮海地区粮食产量增加了1.01亿t,县域粮食产量"南高北低"的空间分异格局明显,苏北、皖北、豫东和鲁西地区的粮食增产显著;2)4个因素中,粮食单产对粮食产量变化起到显著的正向促进作用,复种指数次之,而粮作比例和耕地面积在较大程度上抑制了黄淮海地区粮食产量的增加;3)县域粮食生产因素分解结果表明,县域之间在耕地面积、复种指数、粮作比例和粮食单产效应方面存在明显差异。总体而言,粮食单产效应叠加上复种指数效应使苏北、皖北和豫东多数县域粮食总产量显著增加;而粮作比例效应、复种指数效应和粮食单产效应的叠加使鲁西县域的粮食总产量增加明显。展开更多
以博白大果油茶Camellia gigantocarpa Hu et Huang为材料,通过单因素实验设计和正交设计L18(35)对影响PCR反应体系的主要成分及PCR扩增程序进行优化。建立了稳定的、可重复的博白大果油茶ISSR-PCR扩增反应体系。在20μL的反应体系中,M...以博白大果油茶Camellia gigantocarpa Hu et Huang为材料,通过单因素实验设计和正交设计L18(35)对影响PCR反应体系的主要成分及PCR扩增程序进行优化。建立了稳定的、可重复的博白大果油茶ISSR-PCR扩增反应体系。在20μL的反应体系中,Mg2+浓度为2.5mmol/L,模板DNA用量为20ng,Taq DNA聚合酶为1.75U,dNTPs浓度为0.25mmol/L,引物浓度为0.6mmol/L。反应程序为:94℃预变性4min,94℃变性30s,50℃退火45s,72℃延伸90s,35个循环,72℃延伸7min,4℃保存。展开更多
文摘A brief review of Huang–Rhys theory and Albrechtos theory is provided,and their connection and applications are discussed.The former is a first order perturbative theory on optical transitions intended for applications such as absorption and emission involving localized defect or impurity centers,emphasizing lattice relaxation or mixing of vibrational states due to electron–phonon coupling.The coupling strength is described by the Huang–Rhys factor.The latter theory is a second order perturbative theory on optical transitions intended for Raman scattering,and can in-principle include electron–phonon coupling in both electronic states and vibrational states.These two theories can potentially be connected through the common effect of lattice relaxation – non-orthonormal vibrational states associated with different electronic states.Because of this perceived connection,the latter theory is often used to explain resonant Raman scattering of LO phonons in bulk semiconductors and further used to describe the size dependence of electron–phonon coupling or Huang–Rhys factor in semiconductor nanostructures.Specifically,the A term in Albrechtos theory is often invoked to describe the multi-LO-phonon resonant Raman peaks in both bulk and nanostructured semiconductors in the literature,due to the misconception that a free-exciton could have a strong lattice relaxation.Without lattice relaxation,the A term will give rise to Rayleigh or elastic scattering.Lattice relaxation is only significant for highly localized defect or impurity states,and should be practically zero for either single particle states or free exciton states in a bulk semiconductor or for confined states in a semiconductor nanostructure that is not extremely small.
基金the funding support from the Provincial Natural Science Foundation General Program(No.2015JJ2109)Hunan Province Graduate Student Research Innovation Program(No.CX2018B473)+7 种基金Hunan Traditional Chinese Medicine Scientific Research Program(NO.201463 and NO.2017141)Key Scientific Research Project of Hunan Administration of Traditional Chinese Medicine(NO.201917)University-level Scientific Research Projects of Hunan University of Chinese Medicine(NO.2017029 and NO.2018XJJJ31)The Domestic Firstclass Discipline Construction Project of Chinese Medicine of Hunan University of Chinese MedicineCentral Finance Supported Local High School Construction ProjectState Administration of Traditional Chinese Medicine Ophthalmology Key Discipline Construction ProjectHunan Province Traditional Chinese Medicine Facial Feature Key Discipline Construction ProjectHunan Engineering Technology Research Center for the Prevention and Treatment of Otorhinolaryngologic Diseases and Protection of Visual Function with Chinese Medicine,Hunan Provincial Key Laboratory for the Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Traditional Chinese Medicine
文摘Objective To analyze the effects of Dan Huang Ming Mu Recipe(DHMMR)(a pharmaceutical preparation from herbs and having the function of replenishing vital essence,removing heat,promoting blood circulation and excreting pathogenic water) on diabetic retinopathy(DR) after retinal laser photocoagulation through regulating the expression of vascular endothelial growth factor(VEGF) and pigment epithelium-derived factor(PEDF).Methods Forty male Brown Norway(BN) rats were randomly divided into blank group(group A,10 BN rats) and model group(30 BN rats).DR models were induced by 40 mg/kg streptozotocin(STZ) and the body weight and blood glucose of rats were monitored.After 12-week injection,fluorescein fundus angiography(FFA) and histopathological examination were detected to confirm the successful establishment of DR models.Subsequently,the right eyes of model group rats were conducted retinal laser photocoagulation with the left eyes having no retinal laser photocoagulation and rats of the model group were randomly divided into group B(the model control group),group C(the positive control group),and group D(the DHMMR group),with 10 rats in each group.Rats of the group A and the group B were given vehicle,and the group C were given calcium dobesilate suspension by gavage,and the group D were given DHMMR by gavage.After 4-week gavage,FFA was carried out to observe the fundus microvascular change.Then,the rats were sacrificed to do histopathological examinations and the serum levels of P-selectin,cAMP,cGMP,and the relative expression of the protein of VEGF and PEDF in retina were detected.Results After 12-week STZ injection,the blood glucose of the model group were pronouncedly higher than the blank group(P < 0.01).Fundus micro-hemangioma changes were observed in the rats of the model group through FFA,and the rats of the blank group did not see any changes.The pictures of HE staining showed that the retinal structure of the model group was more disordered than the blank group.After 4-week gavage,treatments with DHMMR showed dramatic reduction of serum levels of Pselectin,cAMP and cGMP compared with the group B(P < 0.01).FFA and histopathological examinations of DHMMR-treated rats revealed significantly suppression of retinal edema,fundus microvascular destruction and retinal destruction distinguishing from the group B.And the relative expression of VEGF protein of the group D and the group A was markedly lower than that of the group B(P < 0.01).The relative expression of PEDF protein of the group D and the group A was dramatically higher than that of the group B to the contrary(P < 0.01).Conclusions DHMMR demonstrates pronounced suppressive effects on the progression of DR after retinal laser photocoagulation,through down-regulating VEGF and upregulating PEDF.
文摘Taking Huang-Huai Plain as an example,evaluation index system is established from four aspects,including the resources condition,the social and economic condition,the agricultural science and technology condition,and the disaster resistant and sustainable production condition.Correlation coefficient method and expert consultation method are used to determine the weight of evaluation index.After the standardization of extreme value,weighted sum method and multiple regression method are adopted to evaluate the influencing factors of agricultural land productivity in Huang-Huai Plain,China.Evaluation result shows that agricultural science and technology condition has a lower contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Resources condition has a higher contribution rate to the productivity of Huang-Huai Plain than that to Henan Province.Both the social and economic condition and the disaster control and sustainable production condition show relatively small contribution rate to the productivity of Huang-Huai Plain.It can be concluded that the main factors affecting the productivity of Huang-Huai Plain are the backward agricultural science and technology level,the poor farmland quality and the farmland infrastructure.Based on this,relevant suggestions are put forward to improve the farmland productivity of Huang-Huai Plain.
文摘Epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI)plays an important role in cancer therapy.However,EGFR is highly expressed in the skin and gives rise to one of the most concerning issues for the EGFR-TKI treatment,namely skin toxicity.Antibiotics and corticosteroids are usually used to treat the EGFR inhibitor-associated skin rash,with prominent side effects over long-time use.Pien Tze Huang(PZH)Unguentum Compositum is a traditional product for external application which is made of traditional Chinese medicine and oil base.Herein,we reported the case of a 50-year-old man who presented with skin rash on the face,head,and back induced by an EGFR-TKI named erlotinib.By using PZH Unguentum Compositum,we observed that the skin rash was mitigated and eventually disappeared.This case report suggests that PZH Unguentum Compositum may be an effective therapy in treating skin rash caused by EGFR-TKI with fewer side effects.
文摘We develop in this paper the theory of multiphonon radiative transition so that someimportant physical quantities that describe effect s of lattice relaxation in electron transitions,for example, Huang--Rhys parameters, lattice relaxation energies and Stokes shifts, becomecomputable directly. The calculated results of the se physical quantities for alexandrite agreewith experimental data very well. Besides, we deduce expressions of intensity distributionand integrated intensity of a multiphonon sideband in non--Condon approximation. The cal-culated values of integrated intensities are obviously better than the intensity fitting resultsof previous work. From these calculated values we can also acquire a quantitative under-standing of the errors of Condon approximation.
文摘实现粮食的持续稳定增长是保障区域粮食安全的关键。分解各因素对粮食生产的作用及影响强度,识别其主导因素,对提升粮食产量具有积极意义。该文运用对数平均迪氏分解方法(logarithmic mean weigh division index method,LMDI)建立因素分解模型,定量评价并对比分析1980-2010年间黄淮海地区县域粮食生产变动的区域因素。结果表明,1)1980-2010年间,黄淮海地区粮食产量增加了1.01亿t,县域粮食产量"南高北低"的空间分异格局明显,苏北、皖北、豫东和鲁西地区的粮食增产显著;2)4个因素中,粮食单产对粮食产量变化起到显著的正向促进作用,复种指数次之,而粮作比例和耕地面积在较大程度上抑制了黄淮海地区粮食产量的增加;3)县域粮食生产因素分解结果表明,县域之间在耕地面积、复种指数、粮作比例和粮食单产效应方面存在明显差异。总体而言,粮食单产效应叠加上复种指数效应使苏北、皖北和豫东多数县域粮食总产量显著增加;而粮作比例效应、复种指数效应和粮食单产效应的叠加使鲁西县域的粮食总产量增加明显。
文摘以博白大果油茶Camellia gigantocarpa Hu et Huang为材料,通过单因素实验设计和正交设计L18(35)对影响PCR反应体系的主要成分及PCR扩增程序进行优化。建立了稳定的、可重复的博白大果油茶ISSR-PCR扩增反应体系。在20μL的反应体系中,Mg2+浓度为2.5mmol/L,模板DNA用量为20ng,Taq DNA聚合酶为1.75U,dNTPs浓度为0.25mmol/L,引物浓度为0.6mmol/L。反应程序为:94℃预变性4min,94℃变性30s,50℃退火45s,72℃延伸90s,35个循环,72℃延伸7min,4℃保存。
