A set of human milk samples,consisting of pools from up to 50 mothers that delivered their first baby was assessed for the persistent organic pollutants(POPs)listed in the Stockholm Convention.It must be noted that on...A set of human milk samples,consisting of pools from up to 50 mothers that delivered their first baby was assessed for the persistent organic pollutants(POPs)listed in the Stockholm Convention.It must be noted that only samples that qualified for the criteria,as established in the global monitoring plan of the Stockholm Convention,following an initial protocol from the World Health Organization,were included.The data do not allow for an assessment of POP concentrations in breast milk with lactation period nor,in most cases and when not indicated otherwise,a comparison within the same country.The assessment does not rank the POPs as to the risk for breastfeeding.Rather the measurements provide a basis for countries to compare among POPs or with other countries.A regional preference for certain POPs could not be identified;thus,taking into account global food supply chains and local production elsewhere does not allow us to prioritize a country for a certain POP.Although the highest concentrations were always found for the sum of DDT,these samples were not prominent in multivariate statistical analyses.The best indicator for the scale of POPs in breast milk was the sampling year:the earlier a national pool was created,the higher and the wider spread were the concentrations:see the example of dioxin-like POPs and indicator PCB.For some POPs,the income of a country seems to indicate scale and POP compounds.The population density was not found to be a suitable predictor or discriminator.Since all POPs seemed to level off and some POPs were only measured after the entry-into-force of the Stockholm Convention in 2004,we do not have a strong indicator to determine POP concentrations in the 1980s or before.展开更多
Background Optimal mineral intakes are important for infant growth and development. However, data on mineral compositions of breast milk in Chinese women are scarce, and most were acquired before 1990. The objectives ...Background Optimal mineral intakes are important for infant growth and development. However, data on mineral compositions of breast milk in Chinese women are scarce, and most were acquired before 1990. The objectives of this study were three-fold： （1） to investigate the mineral compositions of Chinese healthy mothers＇ breast milk in different lactation stages; （2） to explore correlations among mineral concentrations in breast milk; and （3） to explore the associated factors affecting mineral compositions in breast milk. Methods The inductively coupled plasma mass spectrometry （ICP-MS） was used to analyze mineral concentrations in breast-milk of 444 healthy lactating women from three cities in China. A questionnaire was used to survey socio- demographic characteristics and pregnancy history. Food intakes by lactating women were measured using both food frequency questionnaire and one cycle of 24-hour dietary recall. Results Mineral compositions of breast milk varied in different regions. Concentrations of most minerals were higher in the first one or two months of lactation, and then decreased with time, except for magnesium and iron. Inter-mineral correlations existed among several minerals. The calcium-to-phosphorus ratio was above 2：1 in each lactation stage. Women with caesarean section had higher concentration of iodine in the transitional milk （349.9 pg/kg） compared to women with natural delivery （237.5 pg/kg, P〈0.001）. Dietary mineral intakes, supplements, food intake frequencies in the recent 6 months, maternal age and maternal BMI did not show significant correlations with concentrations of milk minerals （all P 〉0.05）. Conclusions Milk minerals decreased with time, and changed most rapidly in the first one or two months of lactation. Caesarean section might affect the iodine level in transitional milk. Chin Med J 2014;127 （14）： 2643-2648展开更多
文摘A set of human milk samples,consisting of pools from up to 50 mothers that delivered their first baby was assessed for the persistent organic pollutants(POPs)listed in the Stockholm Convention.It must be noted that only samples that qualified for the criteria,as established in the global monitoring plan of the Stockholm Convention,following an initial protocol from the World Health Organization,were included.The data do not allow for an assessment of POP concentrations in breast milk with lactation period nor,in most cases and when not indicated otherwise,a comparison within the same country.The assessment does not rank the POPs as to the risk for breastfeeding.Rather the measurements provide a basis for countries to compare among POPs or with other countries.A regional preference for certain POPs could not be identified;thus,taking into account global food supply chains and local production elsewhere does not allow us to prioritize a country for a certain POP.Although the highest concentrations were always found for the sum of DDT,these samples were not prominent in multivariate statistical analyses.The best indicator for the scale of POPs in breast milk was the sampling year:the earlier a national pool was created,the higher and the wider spread were the concentrations:see the example of dioxin-like POPs and indicator PCB.For some POPs,the income of a country seems to indicate scale and POP compounds.The population density was not found to be a suitable predictor or discriminator.Since all POPs seemed to level off and some POPs were only measured after the entry-into-force of the Stockholm Convention in 2004,we do not have a strong indicator to determine POP concentrations in the 1980s or before.
文摘Background Optimal mineral intakes are important for infant growth and development. However, data on mineral compositions of breast milk in Chinese women are scarce, and most were acquired before 1990. The objectives of this study were three-fold： （1） to investigate the mineral compositions of Chinese healthy mothers＇ breast milk in different lactation stages; （2） to explore correlations among mineral concentrations in breast milk; and （3） to explore the associated factors affecting mineral compositions in breast milk. Methods The inductively coupled plasma mass spectrometry （ICP-MS） was used to analyze mineral concentrations in breast-milk of 444 healthy lactating women from three cities in China. A questionnaire was used to survey socio- demographic characteristics and pregnancy history. Food intakes by lactating women were measured using both food frequency questionnaire and one cycle of 24-hour dietary recall. Results Mineral compositions of breast milk varied in different regions. Concentrations of most minerals were higher in the first one or two months of lactation, and then decreased with time, except for magnesium and iron. Inter-mineral correlations existed among several minerals. The calcium-to-phosphorus ratio was above 2：1 in each lactation stage. Women with caesarean section had higher concentration of iodine in the transitional milk （349.9 pg/kg） compared to women with natural delivery （237.5 pg/kg, P〈0.001）. Dietary mineral intakes, supplements, food intake frequencies in the recent 6 months, maternal age and maternal BMI did not show significant correlations with concentrations of milk minerals （all P 〉0.05）. Conclusions Milk minerals decreased with time, and changed most rapidly in the first one or two months of lactation. Caesarean section might affect the iodine level in transitional milk. Chin Med J 2014;127 （14）： 2643-2648
