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A study on the cognitive status of human papillomavirus among adult males in Tianjin based on the health belief model
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作者 Ming Ma Fei-Fei Hong +3 位作者 Yu Liu Xin-Ran Huang Qi-Yun Ma Peng-Xi Liu 《Infectious Diseases Research》 2024年第3期1-8,共8页
Background:To understand the health beliefs and knowledge of human papillomavirus among adult males in Tianjin.Methods:An online questionnaire survey was conducted from 18 January 2023 to 6 March 2023 using snowball s... Background:To understand the health beliefs and knowledge of human papillomavirus among adult males in Tianjin.Methods:An online questionnaire survey was conducted from 18 January 2023 to 6 March 2023 using snowball sampling method.Analyze the health belief scores and human papillomavirus(HPV)and HPV vaccine knowledge scores of adult males in Tianjin,and analyze their influencing factors.Results:A total of 388 adult males in Tianjin were surveyed,with an average total score of 3.23±0.04 for their health beliefs.Among them,the average scores for perceived severity,perceived susceptibility,perceived impairment,perceived benefit,and self-efficacy were 3.41±1.05,2.37±1.20,2.96±1.00,3.51±0.90,and 3.36±1.08,respectively.Multiple linear regression analyses showed education was a factor influencing health beliefs.The average total score of knowledge is 64.09±15.62,with 277 people scoring above 60,and a pass rate of 71.4%.Through multiple linear regression analysis,education level,emotional status,whether disease testing has been done,and whether family and friends have been diagnosed with HPV positive are the main influencing factors.Conclusion:The awareness rate of HPV among adult males in Tianjin is still acceptable,but there are still misconceptions.The overall level of health beliefs is moderate,and the perceived susceptibility level is low.It is necessary to strengthen health education on HPV related knowledge for males and improve their cognitive level. 展开更多
关键词 human papillomavirus Health Beliefs COGNITION adult male human papillomavirus vaccine
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Acute motor axonal neuropathy following anti-rabies human diploid cell vaccine:A rare case and review 被引量:3
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作者 Tanushree Chawla Jyoti Sehgal +1 位作者 Surekha Dabla Vinay Goyal 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2022年第9期425-426,共2页
Rationale:Guillain Barre syndrome(GBS)is an acute neurological illness leading to quadriparesis with respiratory involvement.It can be triggered by infections,vaccinations,surgery,trauma,transplantation and drugs.Anti... Rationale:Guillain Barre syndrome(GBS)is an acute neurological illness leading to quadriparesis with respiratory involvement.It can be triggered by infections,vaccinations,surgery,trauma,transplantation and drugs.Anti-rabies cell culture vaccines introduced to overcome the high rate of neurological complications associated with tissue based rabies vaccine,can be very rarely associated with GBS.Patient concerns:A 50-year-old female presented with acute severe upper back pain evolving into pure motor quadriparesis following administration of human diploid cell vaccine for rabies.Diagnosis:Acute motor axonal neuropathy variant of GBS following anti-rabies human diploid cell vaccine.Interventions:Intravenous high dose steroids.Outcomes:Patient recovered completely within 1 month.Lessons:Although anti-rabies cell culture vaccines are highly immunogenic and safe,they are rarely associated with GBS.Clinicians should be aware of this link because prompt diagnosis and treatment can result in complete recovery and avoid complications. 展开更多
关键词 IMMUNIZATION RABIES Guillain Barre syndrome human diploid cell vaccine Acute motor axonal neuropathy
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Monoarthropathy or Polyarthritis in Adolescent Japanese Girls Who Received Immunization with the Human Papillomavirus Vaccine 被引量:1
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作者 Ryuta Abe Tomomi Kinoshita +1 位作者 Akiyo Hineno Shu-ichi Ikeda 《Case Reports in Clinical Medicine》 2016年第3期109-114,共6页
Joint pain or arthralgia is a common complaint among girls who have received immunization with the human papillomavirus (HPV) vaccine, but the pathogenesis of this disorder has not been completely understood. We repor... Joint pain or arthralgia is a common complaint among girls who have received immunization with the human papillomavirus (HPV) vaccine, but the pathogenesis of this disorder has not been completely understood. We report 2 cases of joint lesions after HPV vaccination. In one case, a 13-year-old patient showed transient arthropathy in the right wrist joint after the first dose of Gardasil<sup>&reg</sup> administered in her left shoulder. In the other case, an 18-year-old patient had migrating joint pain with redness and swelling after the third dose of Cervarix<sup>&reg</sup>. Her serum C-reactive protein and anti-MMP-3 levels were slightly elevated, but no autoantibodies, including rheumatoid factor and anti-CCP antibody, were detected. Although various nonsteroidal anti-inflammatory drugs produced no relief, small doses of both tacrolimus and prednisolone were highly effective for her polyarthritis. The development of reactive joint lesions after HPV vaccination was noteworthy. 展开更多
关键词 human Papillomavirus vaccine Adverse Reaction ARTHRITIS ARTHRALGIA Juvenile Idiopathic Arthritis
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Studies on the correlation between human papilloma virus vaccine and premature ovarian failure
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作者 Wen-Ming Cao Shu-Ling Zhang +2 位作者 Xiu-Rong Wang Li-Li Yu Na Yu 《TMR Cancer》 2020年第6期231-236,共6页
Cervical cancer is the most common malignant tumour of the female reproductive system,resulting in more than 500,000 new cases annually worldwide.In developing countries,cervical cancer ranks second in terms of cancer... Cervical cancer is the most common malignant tumour of the female reproductive system,resulting in more than 500,000 new cases annually worldwide.In developing countries,cervical cancer ranks second in terms of cancer mortality among women.Human papilloma virus is the primary causative agent of cervical cancer,with approximately 70 percent of cervical cancers caused by high-risk types of human papilloma virus 16 and 18.There are currently three types of human papilloma virus vaccines available:bivalent,quadri-valent and nine-valent.However,in recent years,it is reported that cervical cancer vaccine can cause premature ovarian failure.Consequently,an extensive literature search to find out the correlation between human papilloma virus vaccine and premature ovarian failure became a priority.There is no sufficient evidence to support or prove that there is a link between the human papilloma virus vaccine and premature ovarian failure.Hence,the vaccine does not cause premature ovarian failure. 展开更多
关键词 Cervical cancer human papilloma virus vaccine Premature ovarian failure
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The Preparation for Human B7-2 and DC Vaccines and their Roles in Anti-tumor Immunity Against Esophageal CancerIn Vitro
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作者 Jing LU Jun ZHAO Guo-Qiang ZHAO Hong-Yan YANG You-Tian HUANGMing-Yao ZHAO Zi-Ming DONG(Department of Pathophysiology, Medical College of Zhengzhou University, Zhengzhou 450052,China) 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2005年第S1期111-112,共2页
关键词 DC The Preparation for human B7-2 and DC vaccines and their Roles in Anti-tumor Immunity Against Esophageal CancerIn Vitro APC
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Anti-tumor effects induced by gene vaccines co-expressing truncated human prostate specific membrane antigen gene and mouse 4-1BBL
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作者 匡幼林 《外科研究与新技术》 2011年第4期250-250,共1页
Objective To investigate the influence of m4-1BBL on anti-tumor effects induced by truncated human prostate specific membrane antigen ( tPSMA ) gene in mice. Methods A eukaryotic expression plasmid encoding tPSMA and ... Objective To investigate the influence of m4-1BBL on anti-tumor effects induced by truncated human prostate specific membrane antigen ( tPSMA ) gene in mice. Methods A eukaryotic expression plasmid encoding tPSMA and m4-1BBL ( pDC316-tPSMA-IRES m4-1BBL) ,pDC316-tPSMA and pDC316 were constructed. 展开更多
关键词 GENE Anti-tumor effects induced by gene vaccines co-expressing truncated human prostate specific membrane antigen gene and mouse 4-1BBL IRES
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Cervical Cancer Prevention Challenges and Barriers to Cervical Cancer Screening and HPV Vaccinations in Ukraine and Eastern Europe
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作者 Yana Osnytska Lindsey Ryan Martin Annekathryn Goodman 《Health》 2023年第6期525-543,共19页
Objectives: To identify the obstacles and issues that hinder effective cancer prevention efforts in Ukraine. The study aims to provide a comprehensive assessment of the barriers to cancer prevention, including both in... Objectives: To identify the obstacles and issues that hinder effective cancer prevention efforts in Ukraine. The study aims to provide a comprehensive assessment of the barriers to cancer prevention, including both infrastructure and behavioral factors, and identify potential solutions to address these challenges. Study Design: Comprehensive literature review. Methods: The following databases were searched: National Center for Biotechnology Information (NCBI) and PubMed (U.S. National Library of Medicine at the National Institutes of Health). The keywords used in the search included “Cervical Cancer”, “Human Papillomavirus Vaccination (HPV)”, “Ukraine”, “Eastern Europe”, “Healthcare Infrastructure in Disasters”, “Cervical Cancer Prevention”, “Pap Smear”, and “HPV Testing”. Results: A total of 3500 articles were screened. A total of 65 articles met the inclusion criteria. Limited public awareness and limited access to vaccination and screening, combined with inadequate treatment facilities lead to higher rates of cervical cancer. The COVID pandemic, war with Russia, and the Chernobyl disaster are significant factors for the low level of vaccination in Ukraine. Conclusion: The prevention and treatment of cervical cancer in Ukraine face significant challenges due to the inadequate HPV vaccination rates and screening by cytology. Efforts to improve funding and increase education of both the population and health care providers are necessary to increase interventions such as HPV vaccination, cervical cytology, and HPV testing to reduce cervical cancer rates in Ukraine. 展开更多
关键词 Cervical Cancer human Papillomavirus Vaccination Ukraine Eastern Europe Healthcare Infrastructure in Disasters Cervical Cancer Prevention Pap Smear HPV Testing
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Anal intraepithelial neoplasia: A review of diagnosis and management 被引量:3
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作者 Joseph R Roberts Lacey L Siekas Andrew M Kaz 《World Journal of Gastrointestinal Oncology》 SCIE CAS 2017年第2期50-61,共12页
Anal intraepithelial neoplasia(AIN) is a premalignant lesion of the anal mucosa that is a precursor to anal cancer. Although anal cancer is relatively uncommon, rates of this malignancy are steadily rising in the Unit... Anal intraepithelial neoplasia(AIN) is a premalignant lesion of the anal mucosa that is a precursor to anal cancer. Although anal cancer is relatively uncommon, rates of this malignancy are steadily rising in the United States, and among certain high risk populations the incidence of anal cancer may exceed that of colon cancer. Risk factors for AIN and anal cancer consist of clinical factors and behaviors that are associated with the acquisition and persistence of human papilloma virus(HPV) infection. The strongest HPV-associated risk factors are HIV infection, receptive anal intercourse, and high risk sexual behavior. A history of HPVmediated genital cancer, which suggests infection with an oncogenic HPV strain, is another risk factor for AIN/anal cancer. Because progression of AIN to anal cancer is known to occur in some individuals over several years, screening for AIN and early anal cancer, as well as treatment of advanced AIN lesions, is reasonable in certain high-risk populations. Although randomized controlled trials evaluating screening and treatment outcomes are lacking, experts support routine screening for AIN in high risk populations. Screening is performed using anal cytological exams, similar to those performed in cervical cancer screening programs, along with direct tissue evaluation and biopsy via high resolution anoscopy. AIN can be treated using topical therapies such as imiquimod, 5-flurouracil, and trichloroacetic acid, as well as ablative therapies such as electrocautery and laser therapy. Reductions in AIN and anal cancer rates have been shown in studies where high-risk populations were vaccinated against the oncogenic strains of HPV. Currently, the CDC recommends both high-risk and average-risk populations be vaccinated against HPV infection using the quadrivalent or nonavalent vaccines. It is important for clinicians to be familiar with AIN and the role of HPV vaccination, particularly in high risk populations. 展开更多
关键词 Anal cancer Anal intraepithelial neoplasia Anal squamous cell carcinoma human papillomavirus vaccine human papillomavirus
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Sexually transmitted infections of the anus and rectum
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作者 Roland Assi Peter W Hashim +2 位作者 Vikram B Reddy Hulda Einarsdottir Walter E Longo 《World Journal of Gastroenterology》 SCIE CAS 2014年第41期15262-15268,共7页
Sexually transmitted infections(STIs) represent a significant public health concern.Several STIs,once thought to be on the verge of extinction,have recently reemerged.This change is thought to be partially related to ... Sexually transmitted infections(STIs) represent a significant public health concern.Several STIs,once thought to be on the verge of extinction,have recently reemerged.This change is thought to be partially related to an increase in STIs of the anus and rectum.Importantly,the global human immunodeficiency virus and acquired immunodeficiency syndrome(HIV/AIDS) epidemic has contributed to the emergence of particular anorectal lesions that require specialized approaches.In this report,we review common anorectal STIs that are frequently referred to colorectal surgeons in the United States.Epidemiology,clinical presentation,and management are summarized,including the latest treatment recommendations.The particularity of anorectal diseases in HIV/AIDS is addressed,along with recent trends in anal cytology and human papillomavirus vaccination. 展开更多
关键词 Sexually transmitted disease Rectal disease Sexual behavior human papillomavirus human immunodeficiency virus Perianal disease Highly active antiretroviral therapy human papilloma virus vaccines Anal cytology
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China to test new AIDS vaccine on humans
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《Chinese Medical Journal》 SCIE CAS CSCD 2007年第2期168-168,共1页
China is seeking volunteers to participate in its second clinic trial of a new AIDS vaccine early next year, a leading Chinese scientist said On December 18, 2006.
关键词 AIDS China to test new AIDS vaccine on humans
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Clinician Misperceptions about the Importance of Adolescent HPV Vaccination
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作者 Martin C. Mahoney Frances G. Saad-Harfouche +3 位作者 Christy A. Widman Annamaria Masucci Twarozek Deborah O. Erwin Elisa M. Rodriguez 《World Journal of Vaccines》 2016年第1期9-15,共7页
Introduction: Adolescent HPV vaccination rates remain suboptimal. The purpose of the study was to investigate attitudes about HPV vaccine relative to other adolescent vaccines among clinical staff from primary care of... Introduction: Adolescent HPV vaccination rates remain suboptimal. The purpose of the study was to investigate attitudes about HPV vaccine relative to other adolescent vaccines among clinical staff from primary care offices and school based clinics. Methods: We interviewed clinicians in primary care offices and school-based clinics regarding their attitudes about HPV vaccine relative to Tdap and MCV4. Results: Respondents (n = 36) included clinical staff in family medicine (47%), pediatrics (25%), obstetrics/gynecology (19%) and school-based health clinics (8%). Only 3% strongly agreed and 17% agreed that completion of HPV vaccine was more important than completion of pertussis vaccine (Tdap), while 6% strongly agreed and 33% agreed that completion of HPV vaccine was more important than completion of meningitis vaccine (MCV4). Discussion: Providing clinicians with additional information about the cancer prevention benefits of the HPV vaccine and the greater risk for HPV infection/disease relative to other vaccine preventable adolescent diseases may help to increase HPV vaccination rates among adolescents. 展开更多
关键词 human Papillomavirus (HPV) human Papillomavirus vaccine Adolescents Cancer Prevention Clinical Medicine
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Potatoes Deliver Hepatitis Vaccine in Human Trials
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作者 Raulken 肖宏 《当代外语研究》 2005年第4期27-26,共2页
马铃薯是人们再熟悉不过的一种普通蔬菜,但科学家新近研究证明,基因转录过的马铃薯中含有B型肝炎疫苗,服用后可提高人体对B型肝炎病毒(HBV)的免疫能力。科学家正继续研究如何将冷冻干藏的马铃薯作为辅佐性药物成分纳入抗肝炎的胶囊之中... 马铃薯是人们再熟悉不过的一种普通蔬菜,但科学家新近研究证明,基因转录过的马铃薯中含有B型肝炎疫苗,服用后可提高人体对B型肝炎病毒(HBV)的免疫能力。科学家正继续研究如何将冷冻干藏的马铃薯作为辅佐性药物成分纳入抗肝炎的胶囊之中。小小土豆,不可轻瞧哦! 展开更多
关键词 Potatoes Deliver Hepatitis vaccine in human Trials 马铃薯
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Potatoes Deliver Hepatitis Vaccine in Human Trials
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作者 Sarah Graham 张琪 《当代外语研究》 2005年第6期4-4,共1页
近年来研究人员利用转基因植物培育抗病毒疫苗。这种方法既经济,又比利用细菌培育抗病毒疫苗的传统方式安全,因为植物中不含病毒。最近科学家利用转基因土豆培育出了抗B型肝炎疫苗,这对利用植物培育抗病毒疫苗具有重要意义。
关键词 抗病毒疫苗 Potatoes Deliver Hepatitis vaccine in human Trials
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The role of human papillomaviruses in cancer progression
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作者 Pinar Tulay Nedime Serakinci 《Journal of Cancer Metastasis and Treatment》 CAS 2016年第1期201-213,共13页
The importance of human papillomavirus(HPV)infection and its role in the progress of cancer have been widely evaluated.The understanding of HPV association with certain cancers,such as cervical cancer,is very well est... The importance of human papillomavirus(HPV)infection and its role in the progress of cancer have been widely evaluated.The understanding of HPV association with certain cancers,such as cervical cancer,is very well established.A big step forward in the prevention of HPV associated cancers with the use of early detection by screening strategies has also been taken.In the last decade,development of HPV vaccination has reduced the number of cases in HPV infections and infection induced cancers.In this report,we review the HPV pathogenesis and highlight the mechanism of HPV involvement in cancer development. 展开更多
关键词 human papillomavirus CANCER immune response human papillomavirus vaccine
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Immune response to plasmid DNA encoding HPV16-L1 protein
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作者 孙向乐 司履生 +3 位作者 曹瓒孙 王一理 刘天菊 郭建芬 《Chinese Medical Journal》 SCIE CAS CSCD 2000年第3期85-88,共4页
Objective To test the immunogenicity of recombinant plasmid DNA containing human papillomavirus type 16 L1 (HPV16 L1) coding sequence of mice Methods The HPV16 L1 encoding sequence was generate... Objective To test the immunogenicity of recombinant plasmid DNA containing human papillomavirus type 16 L1 (HPV16 L1) coding sequence of mice Methods The HPV16 L1 encoding sequence was generated by polymerase chain reaction (PCR), and inserted into TA cloning vector PCR Ⅱ, then cloned in the eukaryotic expression vector pcDNA3 1 with CMV promoter The recombinant plasmid DNA pcDNA L1 was transferred into Cos 7 cells and used to immunize BALB/c mice via muscular injection The expression of HPV16 L1 in transferred cells was identified by immunospot and immunocytochemistry, which tested specific anti HPV16 L1 antibody in the serum of immunized mice Results Using the immunospot technique, we found L1 protein expression in pcDNA L1 transferred cells The immunocytochemistry studies demonstrated that the L1 protein was located in nuclei In immunized mice, specific anti HPV16 L1 antibodies could be detected by immunospot and immunocytochemistry 28 days after the first immunization and last at least 41 days Conclusions We constructed HPV16 L1 eukaryotic expressing plasmid whose DNA could induce immuno humoral response in mice This observation will be helpful in designing HPV16 prophylactic vaccine 展开更多
关键词 human papillomavirus type 16 · cervical cancer · DNA vaccine
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