Hybrids composed of biocompatible polymers reinforced with inorganic nanomaterials are useful for many biomedical applications including implantation and tissue regeneration and engineering.In this work,we report a ne...Hybrids composed of biocompatible polymers reinforced with inorganic nanomaterials are useful for many biomedical applications including implantation and tissue regeneration and engineering.In this work,we report a new type of hybrid prepared by doping ultrathin nanowires of lanthanide hydroxycarbonates into classical biocompatible poly(citrates-siloxane).The doping of the inorganic nanowires imparts the hybrids with excellent miscibility with the polymeric matrix,producing hybrids with high elasticity and high tensile strength.The hybrids containing Eu(III)and Gd(III)display their respective luminescence and magnetic properties and thus,offer opportunities to monitor the fate of such hybrids when used in vivo.Insignificant degradation and excellent biocompatibility of these hybrids have also been demonstrated.Together,these favorable traits portend useful applications of the newly developed hybrid elastomers.展开更多
基金supported by the National Natural Science Foundation of China(grant nos.21971117,21522106,and 51872224)China Postdoctoral Science Foundation(grant no.2018M642133)+4 种基金the National Key R&D Program of China(grant no.2017YFA0208000)the Fundamental Research Funds for the Central Universities,Nankai University(grant nos.63201071 and ZB19500202)State Key Laboratory of Rare Earth Resource Utilization(grant no.RERU2019001)the 111 Project(grant no.B18030)from ChinaBeijing-Tianjin-Hebei Collaborative Innovation Project(grant no.63201058).
文摘Hybrids composed of biocompatible polymers reinforced with inorganic nanomaterials are useful for many biomedical applications including implantation and tissue regeneration and engineering.In this work,we report a new type of hybrid prepared by doping ultrathin nanowires of lanthanide hydroxycarbonates into classical biocompatible poly(citrates-siloxane).The doping of the inorganic nanowires imparts the hybrids with excellent miscibility with the polymeric matrix,producing hybrids with high elasticity and high tensile strength.The hybrids containing Eu(III)and Gd(III)display their respective luminescence and magnetic properties and thus,offer opportunities to monitor the fate of such hybrids when used in vivo.Insignificant degradation and excellent biocompatibility of these hybrids have also been demonstrated.Together,these favorable traits portend useful applications of the newly developed hybrid elastomers.
