Formation of Superoxide Radical and Hydrogen Peroxide Enhanced by Trinitrotoluene in Rat Liver, Brain, Kidney, and Testicle in Vitro and Monkey Liver in Vivo

Trinitrotoluene (TNT) increased the formation of adrenochrome from adrenaline and the formation of formaldehyde from methanol in rat liver mitochondria and microsomes in vitro as well as in monkey liver mitrochondria and microsomes in vivo. The effects were more prominent at higher TNT concentrations. These findings indicate that TNT enhances the production of superoxide radicals (O_2^-) and hydrogen peroxide (H_2O_2). The production of O_2^- was more prominent in systems containing added TNT than in those containing added benzyl viologen. H_2O_2 production by mitochondria was more pronounced in the liver than in other organs, but its production by microsomes was more pronounced in the brain than in other organs. The results suggest that TNT undergoes cycling reduction which produces oxidative stress. 1989 Academic Press, Inc.

PHOTOCATALYTIG DECOMPOSITION OF METHANOL BY VC1_2 AND TRANSFER OF HYDROGEN AND METHYL FREE RADICALS

The photocatalytic decomposition of methanol in the presence of vanadium dichloride and the transfer of hydrogen and methyl free radicals to the additives and dinitrogen were reported.

Degradation kinetics and mechanism of trace nitrobenzene by granular activated carbon enhanced microwave/hydrogen peroxide system

The kinetics of thedegradation of trace nitrobenzene （NB） by a granular activated carbon （GAC） enhanced microwave （MW）/hydrogen peroxide （H202 ） systemwas studied. Effects of pH, NB initial concentration and tert-butyl alcohol on the removal efficiencywere examined. Itwas found that the reaction rate fitswell to first-order reaction kinetics in the MW/GAC/H202 process. Moreover, GAC greatly enhanced thedegradation rate of NB inwater. Under a given condition （MW power300 W, H202dosage 10 mg/L, pH 6.85 and temperature （60 ± 5）°C）, thedegradation rate of NBwas 0.05214 min 1when4 g/L GACwas added. In general, alkaline pHwas better for NBdegradation; however, the optimum pHwas 8.0 in the tested pH value range of4.0-12.0. At H202dosage of 10 mg/L and GACdosage of4 g/L, the removal of NBwasdecreasedwith increasing initial concentrations of NB, indicating that a low initial concentrationwas beneficial for thedegradation of NB. These results indicated that the MW/GAC/H202 processwas effective for trace NBdegradation inwater. Gas chromatography-mass spectrometry analysis indicated that a hydroxyl radical addition reaction anddehydrogenation reaction enhanced NBdegradation.

Mechanism and rate constants for complete series reactions of 19 fluorophenols with atomic H

Fluorine-containing halogenated fluorophenol may have effect as intermediate species involved in the formation of polyfluorinated dibenzo-p-dioxin/dibenzofurans （PFDDs/Fs）. The mechanism for the atomic H initiated reactions with complete series of nineteen fluorophenol congeners was studies using the density functional theory. At the MPWB1K,/6-31＋G（d,p） level, the geometries and frequencies of reactants, transition states, and products were obtained, and the accurate energetic values were acquired at the MPWB 1K/6-311 ＋G（3df,2p） level. The rate constants were evaluated by the canonical variational transition-state theory with the small curvature tunneling contribution over a wide temperature range of 600-1000 K. The study shows that the intramolecular hydrogen-bond in the ortho-substituted FPs as well as the inductive effect of the electron-withdrawing fluorine and steric repulsion of multiple substitutions may ultimately be responsible for the relative strength of the O-H bonds in FPs. The results can be used for further studies on PFDD/Fs formation mechanism.