Hygienic Production and Post-Harvest Handling Practices of Raw Camel Milk in Degahbour District of Jarar Zone, Somali Regional State, Ethiopia

A cross-sectional study was carried out to assess hygienic production and postharvest handling practices of raw camel milk in Degahbour district. The survey studies were based on a total of 120 (2 production systems * 2 rural kebele * 30 households) milk producers, which were selected from Degahbur district using stratified sampling technique. Data from the selected producers were collected using questionnaire survey and field observation. The results showed that the majority of the sampled household heads in pastoral (93.3%) and agro-pastoral (76.6%) production systems were illiterate. Moreover, none of the respondents in the study area had training on hygienic milk production and postharvest handling practices. The study result also indicated that none of the respondents in the study area washed the udder of milking camel before milking. Moreover, only 6.6% of pastoralists and 25% of agro-pastoralists wash their hands before milking. Equipment made of wooden materials are mainly used for milking, whereas, plastic jerry-cans were most commonly used for storage. About 45% of the pastoralists and 81.6% of the agro-pastoralists were cleaning milk vessels regularly;however, majority of the respondents both production systems were using water from non-tap sources for hygienic practices. Bosciaminimifolia, Acacia ethaica and Blanitesgalabra were the most commonly used plant species for smoking in the study area. Therefore, hygienic production and postharvest handling practices should be followed to improve the quality and suitability of camel milk for its intended use in the study area.

Physical-Chemical Aggressiveness of Solutions of Medicines as a Factor in the Rheology of the Blood inside Veins and Catheters

In experiments in vitro and observations in the clinic in vivo studied the state of the lumen of subcutaneous veins and blood rheology of patients after their interaction with vascular catheters and solutions of medicines based on the values of temperature, volume, concentration, osmotic activity and pH. It is shown that heparin injection in blood not prevent, but solution of 4% sodium bicarbonate injection prevents blood clotting, blood clots and blockage blood clots of veins and of catheters. It is shown that the heating to a temperature of＋42 ℃ with the solution of 4% sodium bicarbonate provides softening action on old dry blood clots in 1 min, and their subsequent irrigation with a warm solution of 4% sodium bicarbonate and 3% hydrogen peroxide provides complete destruction and discoloration of the remaining spots of blood during 2 s. Proposed new medicines and hygiene products for the protection of the veins and installed in them vascular catheters from blockage of blood clots, and for removing blood stains from clothes and body surface patients.

Development and application of a novel method to assess exposure levels of sensitizing and irritating substances leaching from menstrual hygiene products

Menstrual hygiene products(MHPs)like tampons,sanitary towels and panty liners are widely used by women and come in close contact with the intimate parts of the human body,which consist of mucosae that lack the important barrier function of normal skin.Hence,substances leaching from MHP can easily penetrate and become systemically available.This study aims to develop a new in chemico methodology that allows to identify and measure realistic consumer exposure levels of several skin sensitizers and irritants leaching from MHPs under simulated use conditions.To assess the leaching of chemicals from MHPs,a menstrual fluid simulant(MFS)simulating pH,osmolarity and protein binding was first established.Subsequently,an analytical methodology was developed for nine well-known skin sensitizers and skin irritants.In short,the MFS samples underwent salting-out assisted liquid-liquid extraction before ultra-high performance liquid chromatography coupled with a triple-quadrupole mass spectrometry analysis.Validation was performed according to the total error approach with acceptability limits of±15%regarding the total analytical error(including systematic and random bias).Fifteen commercially available MHPs were assessed.Six products were found to leach at least one of the following five sensitizing and irritating compounds:a-isomethyl ionone,benzyl salicylate,hexyl cinnamaldehyde,linalool and piperonal.Piperonal was the most abundant compound leaching from the MHPs,with leaching concentration levels measured to 28.22 mg/g.In addition,the leaching level of benzyl salicylate was found to be 11.03 mg/g.The latter fragrance concentration is above 10 mg/g and would trigger mandatory labelling if the Cosmetic Regulation would apply for MHPs.However,none of the identified and quantified skin sensitizers were mentioned on the packaging.In conclusion,this novel methodology makes it possible to estimate realistic human exposure levels to skin sensitizers and irritants through the use of MHPs.Availability of these exposure estimates is vital to carry out a quantitative health risk assessment of these substances.