Subcutaneous injection of bee venom causes long-term neural activation and hypersensitization in the dorsal horn of the spinal cord,which contributes to the development and maintenance of various pain-related behavior...Subcutaneous injection of bee venom causes long-term neural activation and hypersensitization in the dorsal horn of the spinal cord,which contributes to the development and maintenance of various pain-related behaviors.The unique behavioral 'phenotypes' of nociception and hypersensitivity identified in the rodent bee venom test are believed to reflect a complex pathological state of inflammatory pain and might be appropriate to the study of phenotype-based mechanisms of pain and hyperalgesia.In this review,the spinal processing of the bee venom-induced different 'phenotypes' of pain and hyperalgesia will be described.The accumulative electrophysiological,pharmacological,and behavioral data strongly suggest that different 'phenotypes' of pain and hyperalgesia are mediated by different spinal signaling pathways.Unraveling the phenotype-based mechanisms of pain might be useful in development of novel therapeutic drugs against complex clinic pathological pain.展开更多
Alfalfa (Medicago sativa Leyss) is an important forage crop whose production is hampered by pests, including the alfalfa weevil (Hypera postica Gyllenhal) which is a major problem in many areas. Flaming during dormanc...Alfalfa (Medicago sativa Leyss) is an important forage crop whose production is hampered by pests, including the alfalfa weevil (Hypera postica Gyllenhal) which is a major problem in many areas. Flaming during dormancy could be an alternative control measure. Late fall and early spring flaming at three intensities were compared with pesticide and no treatment for their effects on alfalfa weevil damage and weed density. In four site-years, flaming at high intensity generally reduced weevil damage to alfalfa. When winter annual broadleaf weeds were prevalent, flaming decreased their density. When fall and spring flaming effects were different, spring flaming gave better results.展开更多
基金grants from National Natural Science Foundation of China(No.30325023,30670692)Natural Science Foundation of Beijing Education Committee(No.KZ200510025016)+1 种基金National Basic Research Development Program(973)of China(No.2006CB500808)Innovation Research Team Program of Ministry of Education,China(No.IRT0560)
文摘Subcutaneous injection of bee venom causes long-term neural activation and hypersensitization in the dorsal horn of the spinal cord,which contributes to the development and maintenance of various pain-related behaviors.The unique behavioral 'phenotypes' of nociception and hypersensitivity identified in the rodent bee venom test are believed to reflect a complex pathological state of inflammatory pain and might be appropriate to the study of phenotype-based mechanisms of pain and hyperalgesia.In this review,the spinal processing of the bee venom-induced different 'phenotypes' of pain and hyperalgesia will be described.The accumulative electrophysiological,pharmacological,and behavioral data strongly suggest that different 'phenotypes' of pain and hyperalgesia are mediated by different spinal signaling pathways.Unraveling the phenotype-based mechanisms of pain might be useful in development of novel therapeutic drugs against complex clinic pathological pain.
文摘Alfalfa (Medicago sativa Leyss) is an important forage crop whose production is hampered by pests, including the alfalfa weevil (Hypera postica Gyllenhal) which is a major problem in many areas. Flaming during dormancy could be an alternative control measure. Late fall and early spring flaming at three intensities were compared with pesticide and no treatment for their effects on alfalfa weevil damage and weed density. In four site-years, flaming at high intensity generally reduced weevil damage to alfalfa. When winter annual broadleaf weeds were prevalent, flaming decreased their density. When fall and spring flaming effects were different, spring flaming gave better results.
