Aim: To establish the prevalence and risk factors for hypertension, diabetes and obesity among teaching and non-teaching staff of Bishop Stuart University, Mbarara-Uganda. Background: None communicable diseases (NCDs)...Aim: To establish the prevalence and risk factors for hypertension, diabetes and obesity among teaching and non-teaching staff of Bishop Stuart University, Mbarara-Uganda. Background: None communicable diseases (NCDs) are projected to exceed communicable diseases as the most common causes of death by 2030 in Africa. Most sub-Saharan African countries however lack detailed countrywide data on hypertension and other NCDs risk factors. Cognizant of Uganda’s recent inclusion of Hypertension and diabetes in the health policy agenda, this study was conducted among the university staff in a rural setting to provide benchmark information for design of appropriate interventions. Study Design: This was a descriptive cross-sectional, institutional based survey design. Place and duration of the study: This study was conducted among the teaching and none teaching staff of Bishop Stuart University Mbarara, Uganda from 18th April-6th June 2017. Methodology: A structured questionnaire was used to gather social demographic and risk factors data from the university workers at their work stations. Blood pressure of each participant was measured and Hypertension was defined as systolic BP > 140 and/or diastolic (BP) > 90 mmHg. Anthropometric measurements: Body Mass index (BMI) was done by weight in (Kg) and Height in (M2) to establish weight levels. Obesity was considered at BMI > 40. A random Blood Sugar (RBS) > 200 mg/dl was considered as diabetic. Epi-info version 7 was used to enter data, analyzed using SPSS version 19. Results: A total of 156 University staff aged 25 - 75 years of both sexes, mean age 42 ± 8 were interviewed of whom 51% were males. About 15% were administrative staff, 55% teaching staff, 3% senior lecturers and professors and 25% non-teaching staff. The prevalences of Hypertension, Diabetes, and obesity were 7.7%, 16%, and 28% respectively. But also majority (60.2%) were found at risk of developing both hypertension and diabetes. Less than 20% of the participants were knowledgeable on causes, signs and symptoms and preventive measures for Hypertension but had moderate knowledgeable of the risk factors, the most frequently mentioned risk by 71% was lack of exercise. Despite the awareness of risk factors, majority (61.3%) had not done any form of exercise and 64.1% had not had regular Blood pressure check ups. The study also demonstrated a statistically significant relationship between those aged more than 40 years and having hypertension (X2 = 5.82, P = 0.015, OR = 4.2). Likewise the risk of Diabetes increased with increasing age. Lecturers aged 40 years and above were 5.6 times likely to have diabetes compared to those aged less than 40 years (OR = 5.6, X2 = 16 , P = 0.0005). A significant number of respondents 57/156 (36.5%) reported history of HPT among their family members. Prevalence of obesity and overweight was observed higher in senior administrative staff and lecturers than in lower cadre staff 49% and 34% (p 0.01). Conclusion: Hypertension, Diabetes and obesity are conditions prevalent among the teaching and none teaching staff of BSU, but knowledge on risk factors, clinical presentation and preventive strategies is limited. Routine physical exercises...展开更多
Objective: To determine the prevalence of circadian BP patterns and to assess factors associated with the non-dipping pattern in untreated and treated hypertensive patients, studied separately. Methods: Clinical data ...Objective: To determine the prevalence of circadian BP patterns and to assess factors associated with the non-dipping pattern in untreated and treated hypertensive patients, studied separately. Methods: Clinical data and ABPM were obtained from 52 untreated and 168 treated hypertensive patients referred for ABPM to Monkole Hospital in Kinshasa. Twenty-four ABPM was performed using an oscillometric device. Non-dipping pattern encompasses non-dipping (nocturnal systolic BP dip less than 10% of daytime systolic BP) and reverse dipping (mean night SBP higher than the day SBP). Results: the prevalence of non-dipping pattern was 75% (63.5% non-dipping and 11.5% reverse dipping) and 70% (60.1% non-dipping and 10.1% reverse dipping) in untreated and treated hypertensive patients, respectively. Advanced age (adjusted OR 1.80;95%CI 1.96 - 3.38;p = 0.015), female sex (adjusted OR 2.28;95%CI 1.19 - 4.36;p = 0.013), diabetes (adjusted OR 5.06;95%CI 1.38 - 6.95;p = 0.014), reduced kidney function (adjusted OR 3.10;95%CI 1.50 - 6.43;p = 0.018), inflammation (adjusted OR 2.65;95%CI 1.76 - 6.48;p = 0.031), LVH (adjusted OR 4.45;95%CI 1.78 - 7.67;p = 0.024) and antihypertensive therapy (adjusted OR 0.19;95%CI 0.12 - 0.64;p = 0.018) emerged as the main independent factors significantly associated with the non-dipping pattern in the study population. Conclusion: the non-dipping pattern was a common finding in studied patients and associated with traditional and emerging risk factors suggesting that this abnormal pattern could be a marker of high cardiovascular risk.展开更多
Background: Kidney failure, cardiovascular disease, and early mortality are just a few of the major negative effects of chronic renal disease, a serious global health issue. The considerable financial and public healt...Background: Kidney failure, cardiovascular disease, and early mortality are just a few of the major negative effects of chronic renal disease, a serious global health issue. The considerable financial and public health burden associated with chronic kidney disease can be lessened by raising awareness and adopting better practices for its impact, prevention, and early identification. Objective: In this study, individuals with hypertension and diabetes were evaluated for their knowledge of chronic kidney disease, its prevalence, and its risk factors. Method: It was a hospital-based cross-sectional study conducted on adult (>18 years) patients with diabetes mellitus and hypertension. Each participant provided written informed consent before having their data collected through interviews, medical information, and blood samples for CKD screening. The CKD epidemiology collaboration (CKD-EPI) equation was used to calculate the glomerular filtration rate (GFR) from serum creatinine, and CKD was determined using the estimated GFR (e-GFR). To find independent CKD factors, multivariate logistic regression was employed, with a p-value of 0.05 being regarded as statistically significant. This was accomplished using SPSS (Statistical Program for Social Sciences) version 22.0, IBM Corp., Armonk, NY. Result: A total of 156 participants took part in the study among which 95 (60.9%) were male, most of the participants 82 (52.6%) were aged between 51 - 70 years (mean 59.42 ± 11.007), 76 (48.7%) were unemployed and 97 (62.2%) were single. Overall, the knowledge score of participants on CKD was 65.4% for good knowledge and 34.6% for poor or inadequate knowledge of CKD. More than half of the participants (60%) had chronic kidney disease. Among these, the greatest proportion of CKD patients were those who were hypertensive (88.2%) followed by those who were both hypertensive and diabetic (70.7%). Conclusion: There is poor management of CKD in the South West Region of Cameroon which has contributed greatly to the progression of CKD and increases in the mortality rate.展开更多
Objective To analyze the prevalence of dry and wet age-related macular degeneration(AMD)in patients with diabetes,hypertension and hyperlipidemia,and to analyze the risk factors for AMD.Methods A population-based cros...Objective To analyze the prevalence of dry and wet age-related macular degeneration(AMD)in patients with diabetes,hypertension and hyperlipidemia,and to analyze the risk factors for AMD.Methods A population-based cross-sectional epidemiologic study was conducted involving 14,440 individuals.We assessed the prevalence of dry and wet AMD in diabetic and non-diabetic subjects and analyzed the risk factors for AMD.Results The prevalence of wet AMD in diabetic and non-diabetic patients was 0.3%and 0.5%,respectively,and the prevalence of dry AMD was 17%and 16.4%,respectively.The prevalence of wet AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 0.5%,0.3%,0.2%,and 0.7%,respectively.The prevalence of dry AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 16.6%,16.2%,15.2%,and 17.2%,respectively.Age,sex,body mass index,and use of hypoglycemic drugs or lowering blood pressure drugs were corrected in the risk factor analysis of AMD.Diabetes,diabetes/hypertension,diabetes/hyperlipidemia,and diabetes/hypertension/hyperlipidemia were analyzed.None of the factors analyzed in the current study increased the risk for the onset of AMD.Conclusion There was no significant difference in the prevalence of wet and dry AMD among diabetic and non-diabetic subjects.Similarly,there was no significant difference in the prevalence of wet and dry AMD among subjects with hypertension and hyperlipidemia.Diabetes co-existing with hypertension and hyperlipidemia were not shown to be risk factors for the onset of dry AMD.展开更多
Background Hypertension is one of the most common chronic diseases which threatens human health. However,epidemic data of hypertension guided by new ACC hypertension guideline is limited. Methods Residents from four c...Background Hypertension is one of the most common chronic diseases which threatens human health. However,epidemic data of hypertension guided by new ACC hypertension guideline is limited. Methods Residents from four cities in urban and country areas were enrolled by the probability proportional to size method in Guangdong province,China. Results A total of 19,031 participants were enrolled. The age-standardized prevalence of hypertension was 32.07% guided by previous guideline and 56.67%guided by the new guideline. Notably,when guided by new guideline,the prevalence of hypertension in younger(15~24 years,313%;25~34 years,270%;35~44 years,186%),lower body mass index(BMI<24 kg/m^2,102%)and high-educated(undergraduates,194%;postgraduates,137%)participants increased more compared to older(55~64 years,47%;65~74 years,33%;75~84 years,23%),obesity(BMI≥28 kg/m^2,46.6%)and low-educated(primary school,42%)participants. Age,gender,alcohol taking,BMI,waist circumference,education,medical insurance and hypertension family history were found to be independent risk factors of hypertension in new guidelines. Conclusions The prevalence of hypertension changed greatly when guided by the new hypertension guideline. When applying the new hypertension guideline,subjects with younger age,lower BMI and high-educated tend to be more susceptible to hypertension compared to traditional high risk population. Further studies are needed to explore indicators that can predict the morbidity of hypertension.展开更多
Objectives To investigate the prevalence of hypertension and its primary risk factors in patients with dilated cardiomyopathy (DCM). Methods Three hundred and sixty-two patients with DCM(DCM group)and 401 age-matched ...Objectives To investigate the prevalence of hypertension and its primary risk factors in patients with dilated cardiomyopathy (DCM). Methods Three hundred and sixty-two patients with DCM(DCM group)and 401 age-matched residents (control group) were enrolled randomly in the study, the hypertensive prevalence rate were calculated respectively in the two groups and were compared with each other; the patients in the DCM group were divided into two subgroups (hypertension subgroup and non-hypertension subgroup) according to whether the patients have hypertension; the clinical data related to blood pressure was compared between the two subgroups. Results The prevalence of hypertension in DCM group was significantly higher than that in the control group (32.8% vs. 20.1%, P<0.01); There were no significant differences on the age, gender, occupation and left ventricular ejection fraction (LVEF) between the two subgroups, but the mean heart rate and the percentage of patients who had family history of hypertension were significantly higher in the hypertension subgroup than that in the non-hypertension subgroup (P<0.05 and P<0.01). Conclusions The prevalence of hypertension in patients with DCM was high; The increased activity of sympathetic nervous system and the hypertensive genetic factor may be the main risk factors of hypertension in patients with DCM.展开更多
目的研究高尿酸血症对血压水平及高血压患病率的影响。方法对体检检出5 058例高尿酸血症及性别相同、年龄相同或相近的5058例非高尿酸血症进行分析,探讨其对血压水平、高血压患病率的影响及与多种心血管危险因素的关系。结果高尿酸血症...目的研究高尿酸血症对血压水平及高血压患病率的影响。方法对体检检出5 058例高尿酸血症及性别相同、年龄相同或相近的5058例非高尿酸血症进行分析,探讨其对血压水平、高血压患病率的影响及与多种心血管危险因素的关系。结果高尿酸血症组收缩压、舒张压分别较对照组升高4 mm Hg和3 mm Hg,高血压患病率为41.9%(95%C I:40.5%-43.3%),显著高于对照组31.3%(95%C I:30.0%-32.6%),差异有统计学意义。高尿酸血症组肥胖、高胆固醇血症及高三酰甘油血症患病率均高于对照组,差异有统计学意义。高尿酸血症、男性、年龄增长、肥胖、糖尿病、高胆固醇血症和高三酰甘油血症是高血压的独立危险因素。结论高尿酸血症与较高的血压水平有关,可能是高血压患病率增加的独立危险因素。展开更多
文摘Aim: To establish the prevalence and risk factors for hypertension, diabetes and obesity among teaching and non-teaching staff of Bishop Stuart University, Mbarara-Uganda. Background: None communicable diseases (NCDs) are projected to exceed communicable diseases as the most common causes of death by 2030 in Africa. Most sub-Saharan African countries however lack detailed countrywide data on hypertension and other NCDs risk factors. Cognizant of Uganda’s recent inclusion of Hypertension and diabetes in the health policy agenda, this study was conducted among the university staff in a rural setting to provide benchmark information for design of appropriate interventions. Study Design: This was a descriptive cross-sectional, institutional based survey design. Place and duration of the study: This study was conducted among the teaching and none teaching staff of Bishop Stuart University Mbarara, Uganda from 18th April-6th June 2017. Methodology: A structured questionnaire was used to gather social demographic and risk factors data from the university workers at their work stations. Blood pressure of each participant was measured and Hypertension was defined as systolic BP > 140 and/or diastolic (BP) > 90 mmHg. Anthropometric measurements: Body Mass index (BMI) was done by weight in (Kg) and Height in (M2) to establish weight levels. Obesity was considered at BMI > 40. A random Blood Sugar (RBS) > 200 mg/dl was considered as diabetic. Epi-info version 7 was used to enter data, analyzed using SPSS version 19. Results: A total of 156 University staff aged 25 - 75 years of both sexes, mean age 42 ± 8 were interviewed of whom 51% were males. About 15% were administrative staff, 55% teaching staff, 3% senior lecturers and professors and 25% non-teaching staff. The prevalences of Hypertension, Diabetes, and obesity were 7.7%, 16%, and 28% respectively. But also majority (60.2%) were found at risk of developing both hypertension and diabetes. Less than 20% of the participants were knowledgeable on causes, signs and symptoms and preventive measures for Hypertension but had moderate knowledgeable of the risk factors, the most frequently mentioned risk by 71% was lack of exercise. Despite the awareness of risk factors, majority (61.3%) had not done any form of exercise and 64.1% had not had regular Blood pressure check ups. The study also demonstrated a statistically significant relationship between those aged more than 40 years and having hypertension (X2 = 5.82, P = 0.015, OR = 4.2). Likewise the risk of Diabetes increased with increasing age. Lecturers aged 40 years and above were 5.6 times likely to have diabetes compared to those aged less than 40 years (OR = 5.6, X2 = 16 , P = 0.0005). A significant number of respondents 57/156 (36.5%) reported history of HPT among their family members. Prevalence of obesity and overweight was observed higher in senior administrative staff and lecturers than in lower cadre staff 49% and 34% (p 0.01). Conclusion: Hypertension, Diabetes and obesity are conditions prevalent among the teaching and none teaching staff of BSU, but knowledge on risk factors, clinical presentation and preventive strategies is limited. Routine physical exercises...
文摘Objective: To determine the prevalence of circadian BP patterns and to assess factors associated with the non-dipping pattern in untreated and treated hypertensive patients, studied separately. Methods: Clinical data and ABPM were obtained from 52 untreated and 168 treated hypertensive patients referred for ABPM to Monkole Hospital in Kinshasa. Twenty-four ABPM was performed using an oscillometric device. Non-dipping pattern encompasses non-dipping (nocturnal systolic BP dip less than 10% of daytime systolic BP) and reverse dipping (mean night SBP higher than the day SBP). Results: the prevalence of non-dipping pattern was 75% (63.5% non-dipping and 11.5% reverse dipping) and 70% (60.1% non-dipping and 10.1% reverse dipping) in untreated and treated hypertensive patients, respectively. Advanced age (adjusted OR 1.80;95%CI 1.96 - 3.38;p = 0.015), female sex (adjusted OR 2.28;95%CI 1.19 - 4.36;p = 0.013), diabetes (adjusted OR 5.06;95%CI 1.38 - 6.95;p = 0.014), reduced kidney function (adjusted OR 3.10;95%CI 1.50 - 6.43;p = 0.018), inflammation (adjusted OR 2.65;95%CI 1.76 - 6.48;p = 0.031), LVH (adjusted OR 4.45;95%CI 1.78 - 7.67;p = 0.024) and antihypertensive therapy (adjusted OR 0.19;95%CI 0.12 - 0.64;p = 0.018) emerged as the main independent factors significantly associated with the non-dipping pattern in the study population. Conclusion: the non-dipping pattern was a common finding in studied patients and associated with traditional and emerging risk factors suggesting that this abnormal pattern could be a marker of high cardiovascular risk.
文摘Background: Kidney failure, cardiovascular disease, and early mortality are just a few of the major negative effects of chronic renal disease, a serious global health issue. The considerable financial and public health burden associated with chronic kidney disease can be lessened by raising awareness and adopting better practices for its impact, prevention, and early identification. Objective: In this study, individuals with hypertension and diabetes were evaluated for their knowledge of chronic kidney disease, its prevalence, and its risk factors. Method: It was a hospital-based cross-sectional study conducted on adult (>18 years) patients with diabetes mellitus and hypertension. Each participant provided written informed consent before having their data collected through interviews, medical information, and blood samples for CKD screening. The CKD epidemiology collaboration (CKD-EPI) equation was used to calculate the glomerular filtration rate (GFR) from serum creatinine, and CKD was determined using the estimated GFR (e-GFR). To find independent CKD factors, multivariate logistic regression was employed, with a p-value of 0.05 being regarded as statistically significant. This was accomplished using SPSS (Statistical Program for Social Sciences) version 22.0, IBM Corp., Armonk, NY. Result: A total of 156 participants took part in the study among which 95 (60.9%) were male, most of the participants 82 (52.6%) were aged between 51 - 70 years (mean 59.42 ± 11.007), 76 (48.7%) were unemployed and 97 (62.2%) were single. Overall, the knowledge score of participants on CKD was 65.4% for good knowledge and 34.6% for poor or inadequate knowledge of CKD. More than half of the participants (60%) had chronic kidney disease. Among these, the greatest proportion of CKD patients were those who were hypertensive (88.2%) followed by those who were both hypertensive and diabetic (70.7%). Conclusion: There is poor management of CKD in the South West Region of Cameroon which has contributed greatly to the progression of CKD and increases in the mortality rate.
文摘Objective To analyze the prevalence of dry and wet age-related macular degeneration(AMD)in patients with diabetes,hypertension and hyperlipidemia,and to analyze the risk factors for AMD.Methods A population-based cross-sectional epidemiologic study was conducted involving 14,440 individuals.We assessed the prevalence of dry and wet AMD in diabetic and non-diabetic subjects and analyzed the risk factors for AMD.Results The prevalence of wet AMD in diabetic and non-diabetic patients was 0.3%and 0.5%,respectively,and the prevalence of dry AMD was 17%and 16.4%,respectively.The prevalence of wet AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 0.5%,0.3%,0.2%,and 0.7%,respectively.The prevalence of dry AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 16.6%,16.2%,15.2%,and 17.2%,respectively.Age,sex,body mass index,and use of hypoglycemic drugs or lowering blood pressure drugs were corrected in the risk factor analysis of AMD.Diabetes,diabetes/hypertension,diabetes/hyperlipidemia,and diabetes/hypertension/hyperlipidemia were analyzed.None of the factors analyzed in the current study increased the risk for the onset of AMD.Conclusion There was no significant difference in the prevalence of wet and dry AMD among diabetic and non-diabetic subjects.Similarly,there was no significant difference in the prevalence of wet and dry AMD among subjects with hypertension and hyperlipidemia.Diabetes co-existing with hypertension and hyperlipidemia were not shown to be risk factors for the onset of dry AMD.
基金the Natural Science Foundation of Guangdong Province(No.2015A030313660)the Science and Technology Program of Guangzhou(No.201803040012/No.201604020143/No.201604020018/No.201510010254/No.201604020186)+3 种基金the Medical Science and Technology Research Fund of Guangdong Province(No.B2018023)the National Key Research and Development Program of China(No.2017FYC1307603/No.2016YFC1301305)the Science and Technology Program of Guangdong Province(No.2017B030314041/No.2014B020212008)the Key Area R&D Program of Guangdong Province(No.2019B020227005).
文摘Background Hypertension is one of the most common chronic diseases which threatens human health. However,epidemic data of hypertension guided by new ACC hypertension guideline is limited. Methods Residents from four cities in urban and country areas were enrolled by the probability proportional to size method in Guangdong province,China. Results A total of 19,031 participants were enrolled. The age-standardized prevalence of hypertension was 32.07% guided by previous guideline and 56.67%guided by the new guideline. Notably,when guided by new guideline,the prevalence of hypertension in younger(15~24 years,313%;25~34 years,270%;35~44 years,186%),lower body mass index(BMI<24 kg/m^2,102%)and high-educated(undergraduates,194%;postgraduates,137%)participants increased more compared to older(55~64 years,47%;65~74 years,33%;75~84 years,23%),obesity(BMI≥28 kg/m^2,46.6%)and low-educated(primary school,42%)participants. Age,gender,alcohol taking,BMI,waist circumference,education,medical insurance and hypertension family history were found to be independent risk factors of hypertension in new guidelines. Conclusions The prevalence of hypertension changed greatly when guided by the new hypertension guideline. When applying the new hypertension guideline,subjects with younger age,lower BMI and high-educated tend to be more susceptible to hypertension compared to traditional high risk population. Further studies are needed to explore indicators that can predict the morbidity of hypertension.
文摘Objectives To investigate the prevalence of hypertension and its primary risk factors in patients with dilated cardiomyopathy (DCM). Methods Three hundred and sixty-two patients with DCM(DCM group)and 401 age-matched residents (control group) were enrolled randomly in the study, the hypertensive prevalence rate were calculated respectively in the two groups and were compared with each other; the patients in the DCM group were divided into two subgroups (hypertension subgroup and non-hypertension subgroup) according to whether the patients have hypertension; the clinical data related to blood pressure was compared between the two subgroups. Results The prevalence of hypertension in DCM group was significantly higher than that in the control group (32.8% vs. 20.1%, P<0.01); There were no significant differences on the age, gender, occupation and left ventricular ejection fraction (LVEF) between the two subgroups, but the mean heart rate and the percentage of patients who had family history of hypertension were significantly higher in the hypertension subgroup than that in the non-hypertension subgroup (P<0.05 and P<0.01). Conclusions The prevalence of hypertension in patients with DCM was high; The increased activity of sympathetic nervous system and the hypertensive genetic factor may be the main risk factors of hypertension in patients with DCM.
文摘目的研究高尿酸血症对血压水平及高血压患病率的影响。方法对体检检出5 058例高尿酸血症及性别相同、年龄相同或相近的5058例非高尿酸血症进行分析,探讨其对血压水平、高血压患病率的影响及与多种心血管危险因素的关系。结果高尿酸血症组收缩压、舒张压分别较对照组升高4 mm Hg和3 mm Hg,高血压患病率为41.9%(95%C I:40.5%-43.3%),显著高于对照组31.3%(95%C I:30.0%-32.6%),差异有统计学意义。高尿酸血症组肥胖、高胆固醇血症及高三酰甘油血症患病率均高于对照组,差异有统计学意义。高尿酸血症、男性、年龄增长、肥胖、糖尿病、高胆固醇血症和高三酰甘油血症是高血压的独立危险因素。结论高尿酸血症与较高的血压水平有关,可能是高血压患病率增加的独立危险因素。