Objective To study the effect of sub-hypotherm ia on hypertension cerebral hemorrh age and content of serum endothelin(ET).Method87hypertension cerebral hemorrhage cases were divided into subhypothermia group and cont...Objective To study the effect of sub-hypotherm ia on hypertension cerebral hemorrh age and content of serum endothelin(ET).Method87hypertension cerebral hemorrhage cases were divided into subhypothermia group and control group randoml y,patients in subhy-pothermia group received subhypoth ermia therapy in NICU 6hours after operation or hospitalization.We tested serum ET content with specific radioimmunoassay method 24hours,72hours and 3weeks after therapy,and compared them with control group.Result ET content of two groups increased apparently after 24hours,ET of subhypothermia group was lower than that of control group(P <0.01);it recovered 3weeks after therapy.Conclusion Subhypothermia techniques can appa rently improve prognosis of hyperte nsion cerebral hemorrhage patients,serum ET level may be one important index to evaluate severity of hypertension cerebral hemorrhage.展开更多
Background Hypertensive cerebral hemorrhage (HCH) is an important cerebrovascular disease that poses significant threat to the health of human being, with high incidence and mortality. With the development of mini- ...Background Hypertensive cerebral hemorrhage (HCH) is an important cerebrovascular disease that poses significant threat to the health of human being, with high incidence and mortality. With the development of mini- mally invasive techniques, individualized surgical treatment of HCH is very common. Method During 2003- 2012, according to the condition of using craniotomy, hematoma in small bone window craniotomy and hematoma for treatment of 162 cases of hypertensive cerebral hemorrhage patients. Results Among 162 patients with HCH in our study, 24 had recurrent hemorrhage after surgery, with an incidence of recurrent hemorrhage of 14.8%. Among the 24 recurrent hemorrhages, 22 had hemorrhage in primary hematoma site and two subdural hematomas. Among these patients, 16 died, with a mortality of 9.8%. Death rate and recurrent hemorrhage in the small bone window group were lower than that in the craniotomy group, and "the difference reached statistical significance (P 〈 0.05). Conclusions Individuation in treatment of hypertension must be correctly estimated based on disease condition, comprehensive judgment, selection of appropriate treatment options. Even if that we would reduce mortality, improve the success rate of operation and living quality.展开更多
目的探究分析高血压脑出血患者手术治疗后再出血发生率及其危险因素。方法方便选取2019年12月—2022年12月期间建瓯市立医院310例高血压脑出血手术患者为研究对象,将其根据术后有无引发再出血分为再出血组32例和无出血组278例,比较不同...目的探究分析高血压脑出血患者手术治疗后再出血发生率及其危险因素。方法方便选取2019年12月—2022年12月期间建瓯市立医院310例高血压脑出血手术患者为研究对象,将其根据术后有无引发再出血分为再出血组32例和无出血组278例,比较不同个人基本资料、疾病情况及治疗情况者的术后再出血发生率,分析高血压脑出血患者术后再出血发生的影响因素。结果310例高血压脑出血手术患者中术后发生再出血者发生率为10.32%,不同手术时机、格拉斯哥昏迷评分法(Glasgow Coma Scale,GCS)评分、首次抽吸量、术中责任动脉发现情况、凝血功能障碍、舒张压水平、术后躁动情况及合并肝脏疾病情况者的术后再出血发生率比较,差异有统计学意义(P均<0.05),多因素Logistic分析显示,手术时机(OR=2.815)、首次抽吸量(OR=3.264)、术中责任动脉发现情况(OR=3.001)、凝血功能障碍(OR=3.655)、舒张压水平(OR=2.699)、术后躁动情况(OR=3.330)及合并肝脏疾病情况(OR=3.431)是高血压脑出血患者术后再出血发生的影响因素(P均<0.05)。结论高血压脑出血患者手术治疗后再出血发生率较高,且手术时机、首次抽吸量、术中责任动脉发现情况、凝血功能障碍、舒张压水平、术后躁动情况及合并肝脏疾病情况均是其危险因素,可作为防控措施制订的参考依据。展开更多
目的探讨早期采用高压氧治疗与康复治疗相结合对高血压脑出血患者的神经功能和预后的影响。方法选取2021年12月—2023年1月在济南市莱芜人民医院神经外科接受治疗的80例高血压脑出血患者作为研究对象。根据治疗方法不同分为2组,对照组(...目的探讨早期采用高压氧治疗与康复治疗相结合对高血压脑出血患者的神经功能和预后的影响。方法选取2021年12月—2023年1月在济南市莱芜人民医院神经外科接受治疗的80例高血压脑出血患者作为研究对象。根据治疗方法不同分为2组,对照组(进行早期康复治疗)和观察组(进行早期康复治疗+早期高压氧治疗)各40例。比较2组的治疗效果。结果治疗后,观察组的美国国立卫生研究院神经缺损功能量表(National Institute of Health stroke scale,NIHSS)评分低于对照组(P<0.05);观察组的蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、上肢运动功能评定量表(upper limb Fugl-Meyer assessment,UL-FMA)、下肢运动功能评定量表(Fugl-Meyer scale lower limb part,FMA-L)、脑卒中专用生活质量量表(stroke-specific quality of life scale,SS-QOL)评分高于对照组(P<0.05);观察组的脑血流动力参数水平高于对照组(P<0.05);观察组的预后良好率为95.00%,高于对照组的65.00%(P<0.05)。结论在高血压脑出血患者中,早期采用高压氧和康复训练的联合治疗方法效果显著,能够有效提升患者的神经功能,预后情况也十分理想。展开更多
目的探讨术中B超引导下神经内镜治疗高血压脑出血(hypertensive intracerebral hemorrhage,HICH)的手术方法和技巧。方法回顾性分析我院神经外科于2015年1月至2019年12月收治的50例高血压脑出血患者的临床资料。根据手术方法的不同分为...目的探讨术中B超引导下神经内镜治疗高血压脑出血(hypertensive intracerebral hemorrhage,HICH)的手术方法和技巧。方法回顾性分析我院神经外科于2015年1月至2019年12月收治的50例高血压脑出血患者的临床资料。根据手术方法的不同分为两组,神经内镜组25例,行B超引导下神经内镜微创手术;显微镜组25例,行开颅显微镜下血肿清除术。比较两组手术时间、血肿清除率、术中出血量、重症加强护理病房(intensive care unit,ICU)住院天数、3个月后日常生活活动能力(activity of daily living,ADL)评分。结果与显微镜组比较,神经内镜组手术时间、血肿清除率、术中出血量、ICU住院天数均优于显微镜组(P<0.05),术后3个月恢复良好率神经内镜组为84%,显微镜组为64%,两组比较无统计学差异(P>0.05)。结论B超引导下神经内镜治疗HICH创伤较轻,疗效确切,具有较高的临床推广应用价值。展开更多
文摘Objective To study the effect of sub-hypotherm ia on hypertension cerebral hemorrh age and content of serum endothelin(ET).Method87hypertension cerebral hemorrhage cases were divided into subhypothermia group and control group randoml y,patients in subhy-pothermia group received subhypoth ermia therapy in NICU 6hours after operation or hospitalization.We tested serum ET content with specific radioimmunoassay method 24hours,72hours and 3weeks after therapy,and compared them with control group.Result ET content of two groups increased apparently after 24hours,ET of subhypothermia group was lower than that of control group(P <0.01);it recovered 3weeks after therapy.Conclusion Subhypothermia techniques can appa rently improve prognosis of hyperte nsion cerebral hemorrhage patients,serum ET level may be one important index to evaluate severity of hypertension cerebral hemorrhage.
文摘Background Hypertensive cerebral hemorrhage (HCH) is an important cerebrovascular disease that poses significant threat to the health of human being, with high incidence and mortality. With the development of mini- mally invasive techniques, individualized surgical treatment of HCH is very common. Method During 2003- 2012, according to the condition of using craniotomy, hematoma in small bone window craniotomy and hematoma for treatment of 162 cases of hypertensive cerebral hemorrhage patients. Results Among 162 patients with HCH in our study, 24 had recurrent hemorrhage after surgery, with an incidence of recurrent hemorrhage of 14.8%. Among the 24 recurrent hemorrhages, 22 had hemorrhage in primary hematoma site and two subdural hematomas. Among these patients, 16 died, with a mortality of 9.8%. Death rate and recurrent hemorrhage in the small bone window group were lower than that in the craniotomy group, and "the difference reached statistical significance (P 〈 0.05). Conclusions Individuation in treatment of hypertension must be correctly estimated based on disease condition, comprehensive judgment, selection of appropriate treatment options. Even if that we would reduce mortality, improve the success rate of operation and living quality.
文摘目的探究分析高血压脑出血患者手术治疗后再出血发生率及其危险因素。方法方便选取2019年12月—2022年12月期间建瓯市立医院310例高血压脑出血手术患者为研究对象,将其根据术后有无引发再出血分为再出血组32例和无出血组278例,比较不同个人基本资料、疾病情况及治疗情况者的术后再出血发生率,分析高血压脑出血患者术后再出血发生的影响因素。结果310例高血压脑出血手术患者中术后发生再出血者发生率为10.32%,不同手术时机、格拉斯哥昏迷评分法(Glasgow Coma Scale,GCS)评分、首次抽吸量、术中责任动脉发现情况、凝血功能障碍、舒张压水平、术后躁动情况及合并肝脏疾病情况者的术后再出血发生率比较,差异有统计学意义(P均<0.05),多因素Logistic分析显示,手术时机(OR=2.815)、首次抽吸量(OR=3.264)、术中责任动脉发现情况(OR=3.001)、凝血功能障碍(OR=3.655)、舒张压水平(OR=2.699)、术后躁动情况(OR=3.330)及合并肝脏疾病情况(OR=3.431)是高血压脑出血患者术后再出血发生的影响因素(P均<0.05)。结论高血压脑出血患者手术治疗后再出血发生率较高,且手术时机、首次抽吸量、术中责任动脉发现情况、凝血功能障碍、舒张压水平、术后躁动情况及合并肝脏疾病情况均是其危险因素,可作为防控措施制订的参考依据。
文摘目的探讨早期采用高压氧治疗与康复治疗相结合对高血压脑出血患者的神经功能和预后的影响。方法选取2021年12月—2023年1月在济南市莱芜人民医院神经外科接受治疗的80例高血压脑出血患者作为研究对象。根据治疗方法不同分为2组,对照组(进行早期康复治疗)和观察组(进行早期康复治疗+早期高压氧治疗)各40例。比较2组的治疗效果。结果治疗后,观察组的美国国立卫生研究院神经缺损功能量表(National Institute of Health stroke scale,NIHSS)评分低于对照组(P<0.05);观察组的蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、上肢运动功能评定量表(upper limb Fugl-Meyer assessment,UL-FMA)、下肢运动功能评定量表(Fugl-Meyer scale lower limb part,FMA-L)、脑卒中专用生活质量量表(stroke-specific quality of life scale,SS-QOL)评分高于对照组(P<0.05);观察组的脑血流动力参数水平高于对照组(P<0.05);观察组的预后良好率为95.00%,高于对照组的65.00%(P<0.05)。结论在高血压脑出血患者中,早期采用高压氧和康复训练的联合治疗方法效果显著,能够有效提升患者的神经功能,预后情况也十分理想。
文摘目的探讨术中B超引导下神经内镜治疗高血压脑出血(hypertensive intracerebral hemorrhage,HICH)的手术方法和技巧。方法回顾性分析我院神经外科于2015年1月至2019年12月收治的50例高血压脑出血患者的临床资料。根据手术方法的不同分为两组,神经内镜组25例,行B超引导下神经内镜微创手术;显微镜组25例,行开颅显微镜下血肿清除术。比较两组手术时间、血肿清除率、术中出血量、重症加强护理病房(intensive care unit,ICU)住院天数、3个月后日常生活活动能力(activity of daily living,ADL)评分。结果与显微镜组比较,神经内镜组手术时间、血肿清除率、术中出血量、ICU住院天数均优于显微镜组(P<0.05),术后3个月恢复良好率神经内镜组为84%,显微镜组为64%,两组比较无统计学差异(P>0.05)。结论B超引导下神经内镜治疗HICH创伤较轻,疗效确切,具有较高的临床推广应用价值。