Clinical Effects of the Qi-acupuncture Therapy of TCM on Portal Hypertension

Objective:To explore the effective prevention and treatment of portal hypertension(PH).Methods:A total of 220 patients who came to our hospital from March 2015 to October 2018 were treated.They were randomly divided into the treatment group and the control group,each with 110 cases.Before treatment,there was no significant differences in age,sex,clinical symptoms,signs,laboratory tests and color Doppler ultrasound related examinations between the 2 groups(P>0.05).Among them,the treatment group on the basis of traditional Chinese and Western medicine treatment in our hospital,the Qi-acupuncture therapy of TCM was added.The extra meridian acupoints along with acupoints were selected.The control group received conventional treatment with traditional Chinese and Western medicine in our hospital.Results:There were significant differences in clinical symptoms,signs and chemistry between groups after treatment(P<0.01).There were significant differences in test,color ultrasound related examination and so on(P<0.01).Those in the treatment group was significantly better than the control group(P<0.01).Conclusion:On the basis of the Qi-acupuncture therapy of TCM,selecting extra meridian acupoint and acupoints can effectively treat PH.

Effects of Magnetic Needle Acupuncture on Blood Pressure and Plasma ET-1 Level in the Patient of Hypertension

Endothelin-1 (ET-1) is ever known as a bio-peptidewith the strongest vasoconstrictive action and withwide biological effects.

EFFECT OF ACUPUNCTURE OF FENGCHI (GB 20) ON BLOOD PRESSURE AND SERUM IL-6 and PLASMA ET LEVELS IN PATIENTS WITH HYPERTENSION

Objective：To observe the effect of acupuncture of Fengchi （风池 GB 20） on blood pressure, serum IL-6 and plasma endothelin （ET） contents in patients with hypertension. Methods： Thirty cases of hy-pertension patients were made up of treatment group and treated with acupuncture of Fengchi （GB 20） ; while 20 healthy subjects were made up of control group. Blood pressure was determined before and after the treatment. Fasting blood samples were taken from the cubital venous vessel for detecting serum interleukin （IL）-6 and plasma ET contents with radioimmunoassay before and after acupuncture treatment. Results： Before the treatment, in hypertension patients, serum IL-6 and plasma ET levels were significant higher thanthose in healthy subjects （P〈 0.01 ）; while after the treatment, blood pressure of treatment group declined significantly （ P 〈 0.01 ）, serum IL-6 and plasma ET levels decreased considerably （ P 〈 0.01 ）. Conclusion： Acupuncture of Fengchi （GB 20） can lower blood pressure, regulate cellular immunity and secretion functions of the vascular endothelial cells in hypertension patients.

Common parameters of acupuncture for the treatment of hypertension used in animal models

Hypertension is associated with at least 7.6 million annual deaths worldwide.While pharmacotherapy may provide good control for blood pressure,it sometimes induces adverse effects.Meanwhile,acupuncture has been used for the treatment of cardiovascular diseases,such as hypertension,coronary artery disease,and stroke,but its mechanisms of actions remain poorly understood.The efficacy of acupuncture depends on multiple constituent elements including acupoints,manipulation skills,and implementation programs,which are termed as acupuncture prescription.This review summarized the previous information of experimental use of acupuncture on animals including species,hypertension models,acupoints selection,acupoint location,stimulation protocols,and evaluation of effectiveness to provide useful guidance for researchers when performing acupuncture in animal experiments.

The Effects of Acupuncture on Blood Pressure in Different Patients

Eighty-seven patients with different types of diseases were treated with acupuncture,and the changes of their blood pressure were investigated.The results showed that the total level of systolic pressure in the 87 cases decreased (P<0.05).Especially,the systolic pressure in patients accompanied with hypertension decreased significantly.It is suggested that when acupuncture is adopted to treat other diseases,it can decrease the systolic pressure to a certain extent in patients accompanied with hypertension,but it does not exert significant influence on both systolic and diastolic pressure in patients with normal blood pressure.

CLINICAL OBSERVATION ON PENETRATION NEEDLING TREATMENT OF 65 CASES OF HYPERTENSION

The present paper reports the results of 65 hypertension patients treated with pene-tration needling（point through point method in acupuncture）.For comparison,other ps cases ofhypertension were treated with routine needling method.Changes of blood pressure were ob-served before,during and after treatment.Results showed that the hypotensive effect of the pen-etration needling was significantly superior to that of the routine acupuncture（P【0.05）.Thefollowing-up survey 3 months after treatment showed significant differences between two groupsand between post-treatment and pre-treatment in each group in the mean vahes of systolic and di-astolic pressure（P【0.05）.It reveals that acupuncture has a good hypotensive action,and thepenetration needling is of a certain long-term therapeutic effect.

The Present State and Perspective in Treatment of Primary Osteoporosis by Acupuncture and Moxibustion

Primary osteoporosis, a commonly encountered metabolic bone disease in the postmenopausal women and the aged people, can be classified by modern medicine into postmenopausal osteoporosis (Type I) and senile osteoporosis (Type II). The disease seriously affects health and quality of life of the people as it often cause ostealgia, fracture and the secondary symptoms or diseases. Presently, the pharmacotherapy (including both Chinese herbal drugs and western drugs) remains the first among all other therapeutic methods which are mainly adopted in treatment of the disease at home and abroad. Studies related have been curried out quite early and systematically, and considerable progress has been made, but limit of the pharmacotherapy has also been found. Certain non-drug treatments (such as dietetic therapy, physical exercise, acupuncture and moxibustion, and qigong, especially acupuncture and moxibustion therapy, although with a late start, have been proved effective with satisfactory results. The following is a summary of all the contributions concerned.……

Twenty-eight Cases of Neuritis of Lateral Cutaneous Nerve of Thigh Treated by Acupuncture and Point-Injection

Neuritis of lateral cutaneous nerve of thigh, also called meralgia paresthetica, is a commonly encountered disease in clinical practice. The author has treated 28 cases of meralgia paresthetica since 1996 by acupuncture plus point-injection with satisfactory results. A report follows.Clinical Data Among the 28 cases, 13 were male and 15 female. Their age ranged from 24 to 72 years, most of the patients being 35 to 50 years; the duration of illness varied from one month to ten years and 6 cases were affected on left side, 8 cases on right side and 14 cases on both sides.

The Time-Effect Relationship of Central Action in Acupuncture Treatment for Weight Reduction

Purpose: To study the time-effect relationship of action of acupuncture on the satiety center of ventromedial nucleus of hypothalamus (VMH) in rats with experimental obesity. Methods: Microelectrode recording method of nerve cells and stereotaxic technique for brain were adopted with discharge frequency (Hz/s) of nerve impulse in VMH as the index, and the time-effect of acupuncture action in different periods between groups were observed. Results: Electric activity in acupuncture group was higher than that in the obesity model group (P<0.001) and the normal group (P<0.01) respectively, and the curve of acupuncture action within 2 hours showed irregular fluctuation. Conclusion: Acupuncture can increase excitability of the satiety center, with a better long-term effect.

EFFECTS OF ACUPUNCTURE AT FENGCHI POINT (GB 20) ON CEREBRAL BLOOD FLOW

Blood velocity in the vertebral artery and the basilar artery was observed before and after acupuncture at Fengchi point (GB 20) in 97 patients by transcranial Doppler ultrasonic detecting. The results showed that the blood velocity in patients with either high or low blood flow had significant changes after acupuncture (P

EFFECTS OF ELECTRO ACUPUNCTURE AND TWIRLING REINFORCING-REDUCING MANIPULATIONS ON VOLUME OF MICROCIRCULATORY BLOOD FLOW IN CEREBRAL PIA MATER

Effects of electroacupuncture (EA) and routine acupuncture with twirling reinforcing and reducing manipulation of the needle (RA) both at Zusanli point (St 36) on volume of microcirculatory blood flow in the cerebral pia mater were observed by fenestration of the cranial bone and laser Doppler microcirculatory blood flow analyser. Results showed that both RA and EA could increase the volume of microcirculatory blood flow in the cerebral pia mater; and that the increase in the EA group was superior to that in RA group. This suggests that a moderate and effective stimulation is a key to the production of a regulative effect on the organism.

Clinical Research of Different Syndromes of Hypertension Treated by Acupuncture

Primary hypertension is the most common cardiovascular disease. Some relevant research indicates that puncturing Fengchi （GB 20） can effectively reduce the elevated blood pressure of patient with hypertension. However, is this method effective for all the patients with hypertension？ With regards to this, the author conducted a therapeutic observation in clinic, puncturing Fengchi （GB 20） according to different syndrome of patient with hypertension. Now the conclusion is as follows.

耳穴贴压联合针灸对高血压病患者血压血脂的影响

目的 探析高血压病患者采用耳穴贴压联合针灸治疗对血压与血脂的影响。方法 选择枣庄市立医院2021年3月—2022年3月接诊的90例高血压病患者,按照随机数字表法分为2组,每组45例。对照组口服药物治疗,观察组耳穴贴压联合针灸治疗。比较2组患者血压、血脂、中医证候积分和治疗总有效率。结果 治疗后,观察组舒张压、收缩压均低于对照组,差异有统计学意义(P<0.05);观察组总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)低于对照组,高密度脂蛋白胆固醇(HDL-C)高于对照组,差异均有统计学意义(P<0.05);观察组主症(头痛、眩晕)与次症(心悸、胸闷、畏寒肢冷)中医证候积分均低于对照组,差异有统计学意义(P<0.05)。观察组的治疗总有效率为97.78%(44/45),高于对照组的80.00%(36/45),差异有统计学意义(P<0.05)。结论 高血压病患者采用耳穴贴压联合针灸治疗可以更好地改善血压与血脂,值得推广。

基于压力感受器反射调控探讨针刺降压的作用机制

当心输出量、外周阻力和血量等发生变化时,颈动脉窦和主动脉弓压力感受器反射是维持动脉血压稳定的重要神经反射机制,具有快速调节动脉血压的作用。研究表明针刺具有良好的降压作用,其降压机制可能与上调压力感受器的敏感性、促进神经元传入信息增加、帮助中枢整合传入信号、兴奋迷走神经、抑制交感神经等有关。对针刺影响压力感受器反射的各环节功能而调节血压的作用机制进行阐述,以期为临床科研工作提供一定的参考。

基于ARRIVE指南和SYRCLE工具的针灸治疗骨质疏松症动物实验报告质量评价

目的评价目前针灸治疗骨质疏松症(Osteoporosis,OP)动物实验的报告质量,以期为今后的相关研究提供参考。方法在中国知网、万方、维普、PubMed、Web of Science和Embase六个数据库进行文献检索,检索时间截止2022年12月31日。对检索的文献进行去重、题目及摘要初筛和全文复筛后,使用ARRIVE指南和SYRCLE偏倚评价工具对纳入的文献进行质量评价。结果初检文献共643篇,最终纳入136篇文献进行质量评估。评价发现:针灸治疗OP动物实验的报告质量整体较为均衡,文章总评分呈现缓慢波动上升趋势,目前研究存在的问题集中于纳排标准的设置、随机化与盲法的实施、伦理声明与动物护理的缺失以及实验实施具体细节的不清晰等方面,这些问题带来的选择偏倚、实施偏倚、报告偏倚是影响文献评分的关键因素。结论当前针灸治疗OP的动物实验研究在方法学上存在设计不严谨、实施不透明、报告不规范等问题,建议未来的研究借助SYRCLE偏倚评价工具及ARRIVE指南完善实验的设计思路,改进实施与报告的规范性,进而提高针灸治疗OP动物实验相关结果的严谨性与可信度,以促进针灸治疗OP的临床推广。

针灸治疗高血压性眩晕选穴规律

目的探讨针灸治疗高血压性眩晕的选穴规律,以期为临床选穴提供理论依据。方法检索中国知网、万方、维普期刊数据库2010年1月1日—2023年9月所有针灸治疗高血压性眩晕的临床随机对照试验研究。用Microsoft Excel 2021建立数据库并进行描述分析,用SPSS Statistics 26.0软件和SPSS modeler18.0软件(Apriori算法)进行聚类、关联分析。结果共纳入70篇文献,涉及腧穴65个,总腧穴应用频次为388次。腧穴应用频次最高为太冲。经脉出现频次最高为足阳明胃经。特定穴以原穴应用频次最多。对文献应用频次≥5的腧穴进行关联链接分析,以太冲-曲池配穴应用最多。对应用频次≥10的腧穴进行关联规则分析,支持度最高的为太冲-曲池。对应用频次≥10的腧穴进行聚类分析,显示可分为4类。结论针灸治疗高血压性眩晕的临床选穴具有一定规律性,可为临床上针灸治疗选穴提供参考。

针灸治疗高血压临床研究概况

针灸治疗高血压的方法有:针刺疗法、灸法、综合疗法。针刺疗法包括毫针、电针、耳针、埋针、头针等,灸法包括艾条灸、艾炷灸、热敏灸,综合疗法包括毫针结合药物、灸药结合、针刺联合穴位贴敷、针刺配合推拿、皮内针结合药物、腹针结合药物等。针灸降压的机制可能与抑制RAAS系统相关酶表达、改善代谢紊乱、抑制迷走神经活性、减少氧化应激反应与恢复损伤内皮细胞受体等有关。目前,针灸治疗高血压的研究存在一定局限性,临床针对针灸降血压的研究主要集中在即时和短期疗效,对其远期疗效随访较少涉及,研究中针灸的选穴、作用频次、施术时间、刺激方式等方案差异较大,可能对结果产生一定影响。

温针灸配合依普利酮片治疗气虚血瘀型高血压的疗效观察

目的观察温针灸配合依普利酮片治疗气虚血瘀型高血压的临床疗效及其对患者脂代谢和生活质量的影响。方法将96例气虚血瘀型高血压患者随机分为对照组和观察组,每组48例。对照组给予依普利酮片口服治疗,观察组在对照组基础上加用温针灸治疗。观察两组治疗前后血压各项指标[收缩压(systolic blood pressure,SBP)、舒张压(diastolic blood pressure,DBP)]、血脂各项指标[甘油三酯(triglyceride,TG)、总胆固醇(total cholesterol,TC)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)]、各项中医症候(身疲力乏、恶心胸闷、头重眩晕及痰多纳呆)积分、各项生活质量评分(情感、躯体功能、认知功能及社会参与)及一氧化氮(nitric oxide,NO)、内皮素-1(endothelin-1,ET-1)水平的变化情况。比较两组临床疗效。结果观察组总有效率为93.8%,明显高于对照组的72.9%(P<0.05)。两组治疗后血压各项指标、各项中医症候积分及TG、TC、LDL-C、ET-1水平较同组治疗前均显著降低,HDL-C、NO水平及各项生活质量评分均显著升高,差异均有统计学意义(P<0.05)。观察组治疗后血压各项指标、各项中医症候积分及TG、TC、LDL-C、ET-1水平均明显低于对照组,HDL-C、NO水平及各项生活质量评分均明显高于对照组,差异均具有统计学意义(P<0.05)。结论温针灸配合依普利酮片治疗气虚血瘀型高血压疗效确切,可有效降低血压、血脂,改善中医症候及生活质量,提高NO水平,降低ET-1水平。

基于“互联网+”的揿针疗法结合情志护理对老年高血压病人心理状态及睡眠质量的影响

目的:观察基于“互联网+”的揿针疗法结合情志护理对老年高血压病人心理状态及睡眠质量的影响。方法:选取2022年6月—2023年9月医院收治的94例老年高血压病人为研究对象,随机将其分为对照组、观察组,每组47例。对照组实施常规护理及揿针疗法,观察组在此基础上实施基于“互联网+”的揿针疗法结合情志护理,连续干预3个疗程,比较两组病人干预前后心理状态[焦虑自评量表(SAS)、抑郁自评量表(SDS)评分]、睡眠质量[匹兹堡睡眠质量指数量表(PSQI)评分]、降压效果、生活质量[生活质量综合评定问卷-74(GQOLI-74)评分]、自我健康管理能力。结果:干预后两组病人SAS、SDS、PSQI评分降低,且观察组较对照组低(P<0.05);观察组降压总有效率较对照组高(P<0.05);干预后两组病人GQOLI-74评分及自我健康管理能力评分升高,且观察组较对照组高(P<0.05)。结论:基于“互联网+”的揿针疗法结合情志护理干预可调节老年高血压病人心理状况,提高睡眠质量及自我健康管理能力,有效控制血压水平,提高生活质量。

柴芍解郁丸联合眼周穴位针刺治疗肝郁气滞型高眼压症临床研究

目的:观察柴芍解郁丸联合眼周穴位针刺治疗肝郁气滞型高眼压症(OHT)的临床效果。方法:选择肝郁气滞型OHT患者100例,按随机数字表法分为2组各50例。对照组给予眼周穴位针刺治疗,观察组在对照组基础上联合柴芍解郁丸治疗。比较2组中医证候评分、眼压和最佳矫正视力、血流动力学指标[眼动脉阻力指数(RI)、舒张末期血流速(EDV)、收缩期血流速峰值(PSV)]、临床疗效和复发率。结果:观察组总有效率为98.00%,对照组为84.00%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组眩晕、目珠痛、头痛、烦躁易怒、胸胁胀满等中医证候评分均较治疗前降低(P<0.05),且观察组各项评分均低于对照组(P<0.05)。治疗后,2组眼压较治疗前下降(P<0.05),最佳矫正视力较治疗前升高(P<0.05);且观察组眼压低于对照组(P<0.05),最佳矫正视力高于对照组(P<0.05)。治疗后,2组眼动脉RI值较治疗前降低(P<0.05),EDV、PSV水平较治疗前升高(P<0.05);且观察组RI值低于对照组(P<0.05),EDV、PSV水平高于对照组(P<0.05)。随访2个月,观察组复发率为8.16%,对照组为26.19%,2组比较,差异有统计学意义(P<0.05)。结论:柴芍解郁丸联合眼周穴位针刺能够明显改善患者中医证候及眼部血流,降低眼压,提高最佳矫正视力,减少复发。