Objective:To observe the clinical efficacy of urokinase in combined with minimally invasive hematoma puncture with YL-1 type needle in the treatment of hypertensive cerebral hemorrhage and the effect on blood sugar an...Objective:To observe the clinical efficacy of urokinase in combined with minimally invasive hematoma puncture with YL-1 type needle in the treatment of hypertensive cerebral hemorrhage and the effect on blood sugar and serum CRP.Methods:A total of 84 patients with hypertensive cerebral hemorrhage who were admitted in our hospital were included in the study and divided into the minimally invasive group (n=53) and the conservative group (n=31) according to different treatment protocols. The patients in the two groups were given routine drug treatments. The patients in the observation group were given urokinase in combined with minimally invasive hematoma puncture with YL-1 type needle. The blood sugar and serum CRP levels before and after treatment in the two groups were compared. CT was performed to reexamine the cerebral hematoma and edema volume.Results: The serum CRP and blood sugar levels 3, 7 and 14 d after treatment in the minimally invasive group were significantly lower than those in the conservative group (P<0.05). The cerebral hematoma and edema volume 1, 3, 7, and 14 d after treatment in the minimally invasive group was significantly lower than that in the conservative group (P<0.05).Conclusions: Urokinase in combined with minimally invasive hematoma puncture with YL-1 type needle in the treatment of hypertensive cerebral hemorrhage can significantly alleviate the brain tissue injury, reduce the systemic inflammatory reaction and blood sugar level, and contribute to the rehabilitation.展开更多
目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的...目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的方法为患者进行治疗,观察组采用软通道穿刺引流术为患者进行治疗,比较两组治疗效果。结果与对照组比较,观察组中等量高血压脑出血患者的救治成功率更高,治疗有效性更高,术后并发症发生率更低,且经过治疗后的临床神经功能缺损评分(national institute of health stroke scale,NIHSS)更低,生活质量和睡眠质量更高(P<0.05)。结论针对中等量高血压脑出血患者,采取软通道穿刺引流术的效果更优,患者的治疗有效性和神经功能状况得到改善,并发症情况较低,且患者治疗后生活质量和睡眠质量得到提升,治疗优势突出,可在临床大量推广。展开更多
文摘Objective:To observe the clinical efficacy of urokinase in combined with minimally invasive hematoma puncture with YL-1 type needle in the treatment of hypertensive cerebral hemorrhage and the effect on blood sugar and serum CRP.Methods:A total of 84 patients with hypertensive cerebral hemorrhage who were admitted in our hospital were included in the study and divided into the minimally invasive group (n=53) and the conservative group (n=31) according to different treatment protocols. The patients in the two groups were given routine drug treatments. The patients in the observation group were given urokinase in combined with minimally invasive hematoma puncture with YL-1 type needle. The blood sugar and serum CRP levels before and after treatment in the two groups were compared. CT was performed to reexamine the cerebral hematoma and edema volume.Results: The serum CRP and blood sugar levels 3, 7 and 14 d after treatment in the minimally invasive group were significantly lower than those in the conservative group (P<0.05). The cerebral hematoma and edema volume 1, 3, 7, and 14 d after treatment in the minimally invasive group was significantly lower than that in the conservative group (P<0.05).Conclusions: Urokinase in combined with minimally invasive hematoma puncture with YL-1 type needle in the treatment of hypertensive cerebral hemorrhage can significantly alleviate the brain tissue injury, reduce the systemic inflammatory reaction and blood sugar level, and contribute to the rehabilitation.
文摘目的观察软通道穿刺引流术治疗中等量高血压脑出血的临床效果。方法选取2021年6月—2022年6月在福建省立医院进行手术治疗的300例中等量高血压脑出血患者,采用随机数字表法分为对照组与观察组,每组各150例。对照组采用开颅血肿清除术的方法为患者进行治疗,观察组采用软通道穿刺引流术为患者进行治疗,比较两组治疗效果。结果与对照组比较,观察组中等量高血压脑出血患者的救治成功率更高,治疗有效性更高,术后并发症发生率更低,且经过治疗后的临床神经功能缺损评分(national institute of health stroke scale,NIHSS)更低,生活质量和睡眠质量更高(P<0.05)。结论针对中等量高血压脑出血患者,采取软通道穿刺引流术的效果更优,患者的治疗有效性和神经功能状况得到改善,并发症情况较低,且患者治疗后生活质量和睡眠质量得到提升,治疗优势突出,可在临床大量推广。