Objective:To investigate the correlation between MSCT grading and the prognosis of basal ganglia hypertensive intracerebral hemorrhage.Methods:A total of 86 patients with basal ganglia hypertensive cerebral hemorrhage...Objective:To investigate the correlation between MSCT grading and the prognosis of basal ganglia hypertensive intracerebral hemorrhage.Methods:A total of 86 patients with basal ganglia hypertensive cerebral hemorrhage admitted to our hospital from May 2017 to March 2018 were selected.The clinical data and imaging data were collected from 86 patients.The MSCT images were observed and summarized by two radiologists.Based on the morphology of cisterna ambiens and brain stem,the correlation of MSCT grading to Glasgow Coma Scale(GCS)and Glasgow Outcome Scale(GOS)grading was analyzed by use of Spearman correlation analysis.Results:Among 86 patients,the number of MSCT gradeⅠ,Ⅱ,ⅢandⅣwere 29 cases,38 cases,9 cases and 10 cases respectively.There was no significant correlation between MSCT grading and age,sex as well as types of combined underlying diseases in the patients with basal ganglia hypertensive intracerebral hemorrhage(p>0.05).Spearman correlation analysis showed that there was a positive correlation between MSCT grading and GCS score of basal ganglia hypertensive intracerebral hemorrhage.The higher MSCT grade was,the higher GCS score was(r=0.719,p<0.001).There was a positive correlation between MSCT grading and GOS grading of basal ganglia hypertensive intracerebral hemorrhage.The higher MSCT grade was,the higher GOS grade was,leading to a poor prognosis(r=0.734,p<0.001).86 cases of basal ganglia hypertensive intracerebral hemorrhage showed round or quasi-circular high-density shadows in MSCT images,the CT value ranged from 50 Hu to 80 Hu.Low-density bands surrounded the hematoma in the acute stage,and space-occupying effect could be seen in some patients,which resulted in the compression of ventricular sulcus and cistern and the displacement of midline structure.Subacute basal ganglia hypertensive intracerebral hemorrhage patients showed a relative decrease in the density of hematoma,with the extent of edema gradually reduced,the focus showed a high-density shadow in the center;chronic basal ganglia hypertensive intracerebral hemorrhage focus showed a cystic low-density shadow.Conclusion:MSCT grading of basal ganglia hypertensive intracerebral hemorrhage is positively correlated to GCS and GOS grading.MSCT grading can contribute to the prognostic evaluation to the patients.展开更多
Background:The treatment for spontaneous intracerebral hemorrhage(ICH)is still controversial,especially for hematomas in the basal ganglia.A retrospective case-control study with propensity score matching was performe...Background:The treatment for spontaneous intracerebral hemorrhage(ICH)is still controversial,especially for hematomas in the basal ganglia.A retrospective case-control study with propensity score matching was performed to compare the outcomes of conventional craniotomy and conservative treatment for patients with minor ICH in the basal ganglia.Methods:We retrospectively collected the data of consecutive patients with minor basal ganglia hemorrhage from January 2018 to August 2019.We compared clinical outcomes of two groups using propensity score matching.The extended Glasgow outcome scale obtained by phone interviews based on questionnaires at a 12-month follow-up was used as the primary outcome measure.According to a previous prognosis algorithm,patients were divided into good and poor prognosis groups to obtain a dichotomized(favorable or unfavorable)outcome as the primary outcome.Secondary outcomes included hospitalized complications,mortality,and modified Rankin score at 12 months.Results:A total of 54 patients were analyzed,and the baseline characteristics of patients in the surgery and conservative treatment groups were well matched.The primary favorable outcome at 12 months was significantly higher in the conservative treatment group than in the surgery group(81%vs 44%;OR 1.833,95%CI 1.159-2.900;P=0.005).The incidence of pneumonia in the surgery group was significantly higher than that in the conservative treatment group(P=0.005).Conclusions:It is not recommended to undertake conventional craniotomy for patients with a minor hematoma(25-40 ml)in the basal ganglia.An open craniotomy might induce worse long-term functional outcomes than the conservative treatment.展开更多
Objective:The image data of intracerebral hematoma in hypertensive intracerebral hemorrhage(HICH)patients were obtained by three-dimensional(3D)spiral computed tomography(CT)scan in this study to provide a basis for c...Objective:The image data of intracerebral hematoma in hypertensive intracerebral hemorrhage(HICH)patients were obtained by three-dimensional(3D)spiral computed tomography(CT)scan in this study to provide a basis for clinical minimally invasive surgery and the development and research of related surgical instruments.Methods:From June 2020 to March 2022,33 patients with supratentorial HICH admitted to the Department of Neurosurgery,the First Affiliated Hospital,Zhejiang University,School of Medicine were selected.All patients underwent 3D spiral CT scanning.Multiplanar reconstruction(MPR)was used to reconstruct along any plane to obtain coronal,sagittal,cross-sectional,or arbitrary angle reconstructed images.Then,we observed and measured relevant data indicators on these three planes by measuring tools.Results:All hemorrhage sites of these 33 HICH patients were basal ganglia hemorrhage,including left basal ganglia hemorrhage in 13 cases and right basal ganglia hemorrhage in 20 cases.It was also found that basal ganglia hematomas were usually elliptical,and the anteroposterior diameter was significantly larger than the transverse diameter,almost twice the size of the transverse diameter[(62±10)mm vs.(35±9)mm,P<0.05].Although the depth of the hematoma on the transfrontal(sagittal)approach was significantly greater than that on the transtemporal(transverse)approach[(100±15)mm vs.(59±14)mm,P<0.05],the angle of the hematoma on the transfrontal approach was significantly smaller than that on the transtemporal approach[(37±11)°vs.(70±17)°,P<0.05],which was conducive to improving the clearance rate of the hematoma.Conclusion:During neuroendoscopic surgery for HICH patients,different lengths of the tubular port should be selected according to the transfrontal or transtemporal surgical approach to meet the needs of hematoma removal.展开更多
目的分析不同入路小骨窗开颅显微手术治疗基底节区高血压脑出血的效果。方法选取2019年1月至2022年3月丰城市人民医院收治的88例基底节区高血压脑出血患者作为研究对象,随机分为观察组与对照组,每组44例。两组均行小骨窗开颅显微手术,...目的分析不同入路小骨窗开颅显微手术治疗基底节区高血压脑出血的效果。方法选取2019年1月至2022年3月丰城市人民医院收治的88例基底节区高血压脑出血患者作为研究对象,随机分为观察组与对照组,每组44例。两组均行小骨窗开颅显微手术,对照组采用经颞叶皮质入路手术治疗,观察组采用经侧裂下Rolandic点-岛叶入路手术治疗,比较两组手术情况、血肿清除率、再出血率、术后并发症、术后1个月格拉斯哥昏迷量表(Glasgow coma score,GOS)分级情况及术后1、3、6个月的美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分及世界卫生组织生存质量测定量表(World Health Organization on quality of life brief scale,WHOQOL-BREF)评分。结果两组手术时间、术中出血量、引流管放置时间、行大骨瓣减压例数、住院时间比较差异均无统计学意义;观察组开始手术至颅内压下降时间长于对照组,差异有统计学意义(P<0.05)。观察组术后24 h血肿清除率明显高于对照组,差异有统计学意义(P<0.05);两组再出血率比较差异无统计学意义。观察组术后1个月预后良好率为81.82%,高于对照组的61.36%,差异有统计学意义(P<0.05)。术后1、3、6个月,观察组NIHSS评分均低于对照组,WHOQOL-BREF评分均高于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率为6.82%,低于对照组的25.00%,差异有统计学意义(P<0.05)。结论经侧裂下Rolandic点-岛叶入路小骨窗开颅显微手术治疗基底节区高血压脑出血的效果显著,有助于提升血肿清除率,减少术后并发症发生率,促进术后神经功能的恢复,提高患者预后生存质量。展开更多
目的观察老年基底节区脑出血不同微侵袭手术方式的临床疗效。方法本研究为回顾性病例对照研究,收集2020年1月至2022年12月住院手术治疗的老年基底节区脑出血患者60例,采用神经内镜经额中回入路清除血肿的20例患者为内镜组;采用显微镜经...目的观察老年基底节区脑出血不同微侵袭手术方式的临床疗效。方法本研究为回顾性病例对照研究,收集2020年1月至2022年12月住院手术治疗的老年基底节区脑出血患者60例,采用神经内镜经额中回入路清除血肿的20例患者为内镜组;采用显微镜经侧裂入路清除血肿的20例患者为显微镜组;采用软通道穿刺置管引流术清除血肿的20例患者为穿刺组。观察3组患者手术时间、术中出血量、术后术区残余血肿量、术后术区再出血例数、术后手术并发症发生情况;术前术后7 d格拉斯哥昏迷评分(GCS)、美国国立卫生院卒中量表评分(NIHSS);术后6个月格拉斯哥预后评分(GOS)。结果3组患者术后7 d GCS、NIHSS评分较术前明显改善,3组间比较差异有统计学意义(P<0.05),内镜组和显微镜组明显优于穿刺组(P<0.05);3组患者术后6个月GOS评分差异有统计学意义,内镜组和显微镜组明显优于穿刺组(P<0.05);3组手术时间、术中出血量、术后术区残余血肿量差异有统计学意义(P<0.05),穿刺组手术时间、术中出血量明显小于内镜组和显微镜组(P<0.05),但穿刺组术后术区残余血肿量明显多于内镜组和显微镜组(P<0.05);穿刺组术后术区再出血例数明显多于显微镜组(P<0.05);3组术后肺部感染和泌尿道感染例数比较差异有统计学意义(P<0.05),穿刺组肺部感染、泌尿道感染、手术部位感染明显高于内镜组(P<0.05)。结论临床上要根据老年基底节区脑出血患者的具体情况选择手术方式,条件允许的情况下优先选择神经内镜直视下清除血肿,近期和远期疗效佳,术后并发症发生率低。展开更多
目的:探讨神经内镜在基底节区脑出血手术治疗方面的应用前景。方法:选取2019年3月—2021年3月样本医院收治的31例基底节区脑出血经内镜下手术治疗的患者与同期常规开颅显微镜下手术的38例患者的临床资料,对比分析两组患者术中时间、出...目的:探讨神经内镜在基底节区脑出血手术治疗方面的应用前景。方法:选取2019年3月—2021年3月样本医院收治的31例基底节区脑出血经内镜下手术治疗的患者与同期常规开颅显微镜下手术的38例患者的临床资料,对比分析两组患者术中时间、出血量、术后残余血量、术后第7 d格拉斯哥昏迷量表(GCS)评分、术后并发症及预后情况。结果:内镜组术中时间较显微组短,出血量较显微组少,术后第7 d GCS评分较显微组高,差异有统计学意义(t=12.670、9.608、2.289,P<0.05);术后气管切开、消化道出血内镜组较显微组多,差异有统计学意义(χ^(2)=5.074、5.650,P<0.05)。内镜组预后较显微组佳,差异有统计学意义;预后良好率(ADL分级Ⅰ~Ⅲ级)内镜组较显微组高,差异有统计学意义(χ^(2)=14.380,P<0.05);两组患者死亡率比较,差异无统计学意义(χ^(2)=0.842,P>0.05)。结论:神经内镜有助于基底节区脑出血手术治疗。展开更多
Hemorrhage of the basal ganglia is common in hypertensive patients, and most of the cases are spon- taneous unilateral hemorrhage. Traumatic basal ganglia hemorrhage is uncommon, while bilateral hemorrhage of the basa...Hemorrhage of the basal ganglia is common in hypertensive patients, and most of the cases are spon- taneous unilateral hemorrhage. Traumatic basal ganglia hemorrhage is uncommon, while bilateral hemorrhage of the basal ganglia after trauma is an extremely rare entity. This report described a rare case of bilateral hemorrhage of the basal ganglia after head trauma. We also analyzed the mechanisms and reviewed relative literatures.展开更多
基金funded by Natural Science Foundation of Inner Mongolia Autonomous Region(2013MS1102).
文摘Objective:To investigate the correlation between MSCT grading and the prognosis of basal ganglia hypertensive intracerebral hemorrhage.Methods:A total of 86 patients with basal ganglia hypertensive cerebral hemorrhage admitted to our hospital from May 2017 to March 2018 were selected.The clinical data and imaging data were collected from 86 patients.The MSCT images were observed and summarized by two radiologists.Based on the morphology of cisterna ambiens and brain stem,the correlation of MSCT grading to Glasgow Coma Scale(GCS)and Glasgow Outcome Scale(GOS)grading was analyzed by use of Spearman correlation analysis.Results:Among 86 patients,the number of MSCT gradeⅠ,Ⅱ,ⅢandⅣwere 29 cases,38 cases,9 cases and 10 cases respectively.There was no significant correlation between MSCT grading and age,sex as well as types of combined underlying diseases in the patients with basal ganglia hypertensive intracerebral hemorrhage(p>0.05).Spearman correlation analysis showed that there was a positive correlation between MSCT grading and GCS score of basal ganglia hypertensive intracerebral hemorrhage.The higher MSCT grade was,the higher GCS score was(r=0.719,p<0.001).There was a positive correlation between MSCT grading and GOS grading of basal ganglia hypertensive intracerebral hemorrhage.The higher MSCT grade was,the higher GOS grade was,leading to a poor prognosis(r=0.734,p<0.001).86 cases of basal ganglia hypertensive intracerebral hemorrhage showed round or quasi-circular high-density shadows in MSCT images,the CT value ranged from 50 Hu to 80 Hu.Low-density bands surrounded the hematoma in the acute stage,and space-occupying effect could be seen in some patients,which resulted in the compression of ventricular sulcus and cistern and the displacement of midline structure.Subacute basal ganglia hypertensive intracerebral hemorrhage patients showed a relative decrease in the density of hematoma,with the extent of edema gradually reduced,the focus showed a high-density shadow in the center;chronic basal ganglia hypertensive intracerebral hemorrhage focus showed a cystic low-density shadow.Conclusion:MSCT grading of basal ganglia hypertensive intracerebral hemorrhage is positively correlated to GCS and GOS grading.MSCT grading can contribute to the prognostic evaluation to the patients.
基金the key research and development program of Zhejiang province(2017C03027)National Natural Science Foundation of China(No.81771262)+1 种基金Natural Science Foundation of Zhejiang Province(LQ20H090005)Wenzhou Municipal Science and Technology Bureau Project of China(Y20190568)
文摘Background:The treatment for spontaneous intracerebral hemorrhage(ICH)is still controversial,especially for hematomas in the basal ganglia.A retrospective case-control study with propensity score matching was performed to compare the outcomes of conventional craniotomy and conservative treatment for patients with minor ICH in the basal ganglia.Methods:We retrospectively collected the data of consecutive patients with minor basal ganglia hemorrhage from January 2018 to August 2019.We compared clinical outcomes of two groups using propensity score matching.The extended Glasgow outcome scale obtained by phone interviews based on questionnaires at a 12-month follow-up was used as the primary outcome measure.According to a previous prognosis algorithm,patients were divided into good and poor prognosis groups to obtain a dichotomized(favorable or unfavorable)outcome as the primary outcome.Secondary outcomes included hospitalized complications,mortality,and modified Rankin score at 12 months.Results:A total of 54 patients were analyzed,and the baseline characteristics of patients in the surgery and conservative treatment groups were well matched.The primary favorable outcome at 12 months was significantly higher in the conservative treatment group than in the surgery group(81%vs 44%;OR 1.833,95%CI 1.159-2.900;P=0.005).The incidence of pneumonia in the surgery group was significantly higher than that in the conservative treatment group(P=0.005).Conclusions:It is not recommended to undertake conventional craniotomy for patients with a minor hematoma(25-40 ml)in the basal ganglia.An open craniotomy might induce worse long-term functional outcomes than the conservative treatment.
基金This work was supported by the Project of Zhejiang Medical Science and Technology Plan[2020PY044].
文摘Objective:The image data of intracerebral hematoma in hypertensive intracerebral hemorrhage(HICH)patients were obtained by three-dimensional(3D)spiral computed tomography(CT)scan in this study to provide a basis for clinical minimally invasive surgery and the development and research of related surgical instruments.Methods:From June 2020 to March 2022,33 patients with supratentorial HICH admitted to the Department of Neurosurgery,the First Affiliated Hospital,Zhejiang University,School of Medicine were selected.All patients underwent 3D spiral CT scanning.Multiplanar reconstruction(MPR)was used to reconstruct along any plane to obtain coronal,sagittal,cross-sectional,or arbitrary angle reconstructed images.Then,we observed and measured relevant data indicators on these three planes by measuring tools.Results:All hemorrhage sites of these 33 HICH patients were basal ganglia hemorrhage,including left basal ganglia hemorrhage in 13 cases and right basal ganglia hemorrhage in 20 cases.It was also found that basal ganglia hematomas were usually elliptical,and the anteroposterior diameter was significantly larger than the transverse diameter,almost twice the size of the transverse diameter[(62±10)mm vs.(35±9)mm,P<0.05].Although the depth of the hematoma on the transfrontal(sagittal)approach was significantly greater than that on the transtemporal(transverse)approach[(100±15)mm vs.(59±14)mm,P<0.05],the angle of the hematoma on the transfrontal approach was significantly smaller than that on the transtemporal approach[(37±11)°vs.(70±17)°,P<0.05],which was conducive to improving the clearance rate of the hematoma.Conclusion:During neuroendoscopic surgery for HICH patients,different lengths of the tubular port should be selected according to the transfrontal or transtemporal surgical approach to meet the needs of hematoma removal.
文摘目的分析不同入路小骨窗开颅显微手术治疗基底节区高血压脑出血的效果。方法选取2019年1月至2022年3月丰城市人民医院收治的88例基底节区高血压脑出血患者作为研究对象,随机分为观察组与对照组,每组44例。两组均行小骨窗开颅显微手术,对照组采用经颞叶皮质入路手术治疗,观察组采用经侧裂下Rolandic点-岛叶入路手术治疗,比较两组手术情况、血肿清除率、再出血率、术后并发症、术后1个月格拉斯哥昏迷量表(Glasgow coma score,GOS)分级情况及术后1、3、6个月的美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分及世界卫生组织生存质量测定量表(World Health Organization on quality of life brief scale,WHOQOL-BREF)评分。结果两组手术时间、术中出血量、引流管放置时间、行大骨瓣减压例数、住院时间比较差异均无统计学意义;观察组开始手术至颅内压下降时间长于对照组,差异有统计学意义(P<0.05)。观察组术后24 h血肿清除率明显高于对照组,差异有统计学意义(P<0.05);两组再出血率比较差异无统计学意义。观察组术后1个月预后良好率为81.82%,高于对照组的61.36%,差异有统计学意义(P<0.05)。术后1、3、6个月,观察组NIHSS评分均低于对照组,WHOQOL-BREF评分均高于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率为6.82%,低于对照组的25.00%,差异有统计学意义(P<0.05)。结论经侧裂下Rolandic点-岛叶入路小骨窗开颅显微手术治疗基底节区高血压脑出血的效果显著,有助于提升血肿清除率,减少术后并发症发生率,促进术后神经功能的恢复,提高患者预后生存质量。
文摘目的观察老年基底节区脑出血不同微侵袭手术方式的临床疗效。方法本研究为回顾性病例对照研究,收集2020年1月至2022年12月住院手术治疗的老年基底节区脑出血患者60例,采用神经内镜经额中回入路清除血肿的20例患者为内镜组;采用显微镜经侧裂入路清除血肿的20例患者为显微镜组;采用软通道穿刺置管引流术清除血肿的20例患者为穿刺组。观察3组患者手术时间、术中出血量、术后术区残余血肿量、术后术区再出血例数、术后手术并发症发生情况;术前术后7 d格拉斯哥昏迷评分(GCS)、美国国立卫生院卒中量表评分(NIHSS);术后6个月格拉斯哥预后评分(GOS)。结果3组患者术后7 d GCS、NIHSS评分较术前明显改善,3组间比较差异有统计学意义(P<0.05),内镜组和显微镜组明显优于穿刺组(P<0.05);3组患者术后6个月GOS评分差异有统计学意义,内镜组和显微镜组明显优于穿刺组(P<0.05);3组手术时间、术中出血量、术后术区残余血肿量差异有统计学意义(P<0.05),穿刺组手术时间、术中出血量明显小于内镜组和显微镜组(P<0.05),但穿刺组术后术区残余血肿量明显多于内镜组和显微镜组(P<0.05);穿刺组术后术区再出血例数明显多于显微镜组(P<0.05);3组术后肺部感染和泌尿道感染例数比较差异有统计学意义(P<0.05),穿刺组肺部感染、泌尿道感染、手术部位感染明显高于内镜组(P<0.05)。结论临床上要根据老年基底节区脑出血患者的具体情况选择手术方式,条件允许的情况下优先选择神经内镜直视下清除血肿,近期和远期疗效佳,术后并发症发生率低。
文摘目的:探讨神经内镜在基底节区脑出血手术治疗方面的应用前景。方法:选取2019年3月—2021年3月样本医院收治的31例基底节区脑出血经内镜下手术治疗的患者与同期常规开颅显微镜下手术的38例患者的临床资料,对比分析两组患者术中时间、出血量、术后残余血量、术后第7 d格拉斯哥昏迷量表(GCS)评分、术后并发症及预后情况。结果:内镜组术中时间较显微组短,出血量较显微组少,术后第7 d GCS评分较显微组高,差异有统计学意义(t=12.670、9.608、2.289,P<0.05);术后气管切开、消化道出血内镜组较显微组多,差异有统计学意义(χ^(2)=5.074、5.650,P<0.05)。内镜组预后较显微组佳,差异有统计学意义;预后良好率(ADL分级Ⅰ~Ⅲ级)内镜组较显微组高,差异有统计学意义(χ^(2)=14.380,P<0.05);两组患者死亡率比较,差异无统计学意义(χ^(2)=0.842,P>0.05)。结论:神经内镜有助于基底节区脑出血手术治疗。
文摘Hemorrhage of the basal ganglia is common in hypertensive patients, and most of the cases are spon- taneous unilateral hemorrhage. Traumatic basal ganglia hemorrhage is uncommon, while bilateral hemorrhage of the basal ganglia after trauma is an extremely rare entity. This report described a rare case of bilateral hemorrhage of the basal ganglia after head trauma. We also analyzed the mechanisms and reviewed relative literatures.
