n-李代数的Hypo-幂零理想

研究n-李代数的Hypo-幂零理想,及具有5维极大Hypo-幂零理想的所有可解3-李代数的结构。证明可解非幂零n-李代数一定存在Hypo-幂零理想,且其幂零根基的余维数等于1。给出可解非幂零3-李代数的极大Hypo-幂零理想与3-李代数的维数关系。对具有一类特殊5-维极大次幂零理想的可解3-李代数的每一类3-李代数,分别研究了其导代数维数序列DS及下降中心维数序列CS,及他们之间的关系。

HYPO2000与单纯形定位方法对比及作为速报算法的可行性分析

选取福建、陕西的12次爆破事件,安徽测震台网的6次速报地震事件以及4次地震台站出现GPS时钟错误的地震事件,运用两种地震定位方法进行定位。结果表明:对于网内地震,HYPO2000程序稍优于单纯形定位结果;对于网缘及网外地震,单纯形优于HYPO2000程序的定位结果。

Hyponatremia in cirrhosis:Pathophysiology and management

Hyponatremia is frequently seen in patients with ascites secondary to advanced cirrhosis and portal hypertension.The development of ascites in patients with cirrhosis is multi-factorial.Portal hypertension and the associated systemic vasodilation lead to activation of the sodium-retaining neurohumoral mechanisms which include the renin-angiotensin-aldosterone system,sympathetic nervous system and antidiuretic hormone(ADH).The net effect is the avid retention of sodium and water to compensate for the low effective circulatory volume resulting in the development of ascites.Although not apparent in the early stages of cirrhosis,the progression of cirrhosis and ascites leads to impairment of the kidneys to eliminate solutefree water.This leads to additional compensatory mechanisms including non-osmotic secretion of ADH,also known as arginine vasopressin,further worsening excess water retention and thereby hyponatremia.Hyponatremia is associated with increased morbidity and mortality in patients with cirrhosis,and is an important prognostic marker both before and after liver transplant.The management of hyponatremia in this setting is a challenge as conventional therapy for hyponatremia including fluid restriction and loop diuretics are frequently inefficacious.In this review,we discuss the pathophysiology and various treatment modalities,including selective vasopressin receptor antagonists,for the management of hyponatremia in patients with cirrhosis.

A short-term study of corneal collagen cross-linking with hypo-osmolar riboflavin solution in keratoconic corneas

AIM: To report the 3mo outcomes of collagen crosslinking(CXL) with a hypo-osmolar riboflavin in thin corneas with the thinnest thickness less than 400 μm without epithelium.METHODS: Eight eyes in 6 patients with age 26.2±4.8y were included in the study. All patients underwent CXL using a hypo-osmolar riboflavin solution after its de-epithelization. Best corrected visual acuity, manifest refraction, the thinnest corneal thickness, and endothelial cell density were evaluated before and 3mo after the procedure.RESULTS: The mean thinnest thickness of the cornea was 408.5 ±29.0 μm before treatment and reduced to369.8 ±24.8 μm after the removal of epithelium. With the application of the hypo-osmolar riboflavin solution, the thickness increased to 445.0 ±26.5 μm before CXL and recover to 412.5 ±22.7 μm at 3mo after treatment, P =0.659). Before surgery, the mean K-value of the apex of the keratoconus corneas was 57.6 ±4.0 diopters, and slightly decreased(54.7±4.9 diopters) after surgery(P =0.085). Mean best-corrected visual acuity was 0.55 ±0.23 logarithm of the minimal angle of resolution, and increased to 0.53±0.26 logarithm after surgery(P =0.879).The endothelial cell density was 2706.4 ±201.6 cells/mm2 before treatment, and slightly decreased( 2641. 2 ±218.2 cells/mm2) at last fellow up(P =0.002).CONCLUSION: Corneal collagen cross-linking with a hypo-osmolar riboflavin in thin corneas seems to be a promising treatment. Further study should be done to evaluate the safety and efficiency of CXL in thin corneas for the long-term.

Predictive value of hypo-osmotic swelling test to identifyviable non-motile sperm

Aim: To determine the predictive value of the hypo-osmotic swelling (HOS) test to identify viable, non-motile sperm. Methods: Semen samples from 20 men with severe asthenozoospermia underwent traditional seminal analysis, eosin-nigrosin (EN) staining and the HOS test. A further EN stain was then performed on a HOS pre-treated aliquot and a total of 2000 further sperm examined. Results: The median sperm density was 5.1 million/mL (IQR 4.3-13.1) and the median motility was 3.0 % (IQR 0-7). Seven samples showed complete asthenozoospermia. Initial EN staining showed 59 % viability (range 48-69) despite the poor standard parameters and 47 % (range 33-61) in the complete asthenozoospermia subgroup. The HOS test showed 49.9 % reacted overall (range 40-59) and 41.7 % (range 22-61) in the complete asthenozoospermia subgroup. The combined HOS/EN stain showed the positive predictive value of the HOS test to identify viable sperm was 84.2 % overall and 79.7 % in the complete asthenozoospermia subgroup. Conclusion: The HOS test can effectively predict sperm viability in patients with severe and complete asthenozoospermia.

Research on mold flux for hypo-peritectic steel at high casting speed

Mold fluxes having adaptable properties were developed in the laboratory to solve quality defects, such as depressions and longitudinal cracks when casting hypo-peritectic steel at high casting speed. Firstly, the effect of components on the high basicity mold flux properties was first studied using the orthogonal method. In the scope of the studied content, Li2O has the largest effect on the melting temperature, and the least effect on the viscosity; CaF2 has the largest effect on the viscosity, and the least effect on the melting temperature; Na2O and CaO/SiO2 have no obvious influence on the melting temperature and viscosity. Secondly, two powders （Z1 and Z6） have reasonable viscosity-temperature curves, higher solidification temperatures, and porous structure after solidification, but the crystal property of Z6 is worse than that of Z1, and thus Z1 is more suitable for continuous casting hypo-peritectic steel at high casting speed. Thirdly, a higher basicity of powder, a less free enthalpy of crystal compound, and a lower baffle energy are good for a higher tendentiousness of crystal.

THE EFFECT OF HYPO－OSMOLAR SOLUTIONS WITH HIBITANE ON SHED CANCER CELLS IN PERITONEAL CAVITY OF PATIENTS WITH GASTRIC CANCER

For 100 patients with gastric cancer, intraoperative intraperitoneal perfusion(IOIPP)using double-distilled water(D.D.W)with hibitane 37℃ for 5 minutes was performed.The anticancer effects were assessed cytologically in pre-IOIPP and post-IOPP specimens of the abdominal effusion and/or lavaged peritoneal fluid.The radical gastrectomy was performed in 65 of 93 cases with advanced gastric cancer, shed cancer cells in peritoneal cavity were detected in 16 of 65 cases with pre-IOIPP(24.62%)and to 3 of post-IOIPP cases(4.62%).There was significant difference between the two groups(P<0.01) . Shed cancer cells were inactivated in vivo estimated by the trypan-blue staining technique in 7 cases with radical surgery.But the effect of the IOIPP on shed cancer calls was not significant in cases with peritoneal metastasis. Also there were shed cancer cells in peritoneal cavity of patients with SS cancer histologically before the IOIPP(15. 56%)and iatrogenic diffusion of cancer cells during operation(7/24)in thisarticle.The above results indicated that the IOIPP with hypo-osmolar solution containing hibitane, 37℃ for 5 min was indispensable and useful for the killing of peritoneal shed cancer cells in order to prevent postoperative peritoneal recurrence in patients with radical surgery of advanced gastric cancer regardless of conditions of serosal invasion.

Transcriptomic analysis reveals putative osmoregulation mechanisms in the kidney of euryhaline turbot Scophthalmus maximus responded to hypo-saline seawater

Turbot harbor a relatively remarkable ability to adapt to opposing osmotic challenges and are an excellent model species to study the physiological adaptations of flounder associated with osmoregulatory plasticity.The kidney transcriptome of turbot treated 24 h in water of hypo-salinity(salinity 5)and seawater(salinity 30)was sequenced and characterized.In silico analysis indicated that all unigenes had significant hits in seven databases.The functional annotation analysis of the transcriptome showed that the immune system and biological processes associated with digestion,absorption,and metabolism played an important role in the osmoregulation of turbot in response to hypo-salinity.Analysis of biological processes associated with inorganic channels and transporters indicated that mineral absorption and bile secretion contributed to iono-osmoregulation resulting in cell volume regulation and cell phenotypic plasticity.Moreover,we analyzed and predicted the mechanisms of canonical signaling transduction.Biological processes involved in renin secretion,ECM-receptor interaction,adherens junction,and focal adhesion played an important role in the plasticity phenotype in hypo-stress,while the signal transduction network composed of the MAPK signaling pathway and PI3K-Akt signaling pathway with GABAergic synapse,worked in hypoosmoregulation signal transduction in the turbot.In addition,analysis of the tissue specificity of targeted gene expression using qPCR during salinity stress was carried out.The results showed that the kidney,gill,and spleen were vital regulating organs of osmotic pressure,and the osmoregulation pattern of euryhaline fish dif fered among species.

%Micro/%Hypo比值在珠蛋白生成障碍性贫血和缺铁性贫血辅助诊断中的应用价值

目的探讨小红细胞百分比(%Micro)与低色素红细胞百分比(%Hypo)的比值对常见3种珠蛋白生成障碍性贫血(地贫)和缺铁性贫血(IDA)的诊断价值。方法选择49例IDA患者、24例轻型α地贫患者、24例轻型β地贫患者、24例静止型α地贫患者、120例健康体检者作为研究对象,将其分为6组:健康组、IDA组、轻型α地贫组、轻型β地贫组、静止型α地贫组、轻型地贫组(为轻型α地贫组和轻型β地贫组的合并组)。分别检测各组%Micro和%Hypo并计算出两者比值,对结果进行分析比较。结果轻型地贫组与IDA组之间,轻型地贫组、IDA组分别与健康组之间,%Micro/%Hypo比较差异均有统计学意义(P<0.01)。静止型α地贫组与健康组之间,轻型α地贫组与轻型β地贫组之间,%Micro/%Hypo比较差异均无统计学意义(P>0.05)。以0.9作为%Micro/%Hypo鉴别诊断轻型地贫和IDA的判别值,则其诊断轻型地贫的敏感度、特异度、准确度分别为91.67%、91.89%、91.72%,诊断IDA的敏感度、特异度、准确度分别为91.94%、91.25%、91.18%。结论 %Micro/%Hypo对轻型α地贫、轻型β地贫、IDA有较好的鉴别诊断和辅助筛查价值,对静止型α地贫的临床价值不大。

Construction and analysis of dynamic solidification curves for non-equilibrium solidification process in lost-foam casting hypoeutectic gray cast iron

Most lost-foam casting processes involve non-equilibrium solidification dominated by kinetic factors, while construction of a common dynamic solidification curve is based on pure thermodynamics, not applicable for analyses and research of non-equilibrium macro-solidification processes, and the construction mode can not be applied to nonequilibrium solidification process. In this study, the construction of the dynamic solidification curve(DSC) for the nonequilibrium macro-solidification process included: a modified method to determine the start temperature of primary austenite precipitation(T_(AL)) and the start temperature of eutectic solidification(T_(ES)); double curves method to determine the temperature of the dendrite coherency point of primary austenite(T-(AC)) and the temperature of eutectic cells collision point(T_(EC)); the "technical solidus" method to determine the end temperature of eutectic reaction(T_(EN)). For this purpose, a comparative testing of the non-equilibrium solidification temperature fields in lost-foam casting and green sand mold casting hypoeutectic gray iron was carried out. The thermal analysis results were used to construct the DSCs of both these casting methods under non-equilibrium solidification conditions. The results show that the transformation rate of non-equilibrium solidification in hypoeutectic gray cast iron is greater than that of equilibrium solidification. The eutectic solidification region presents a typical mushy solidification mode. The results also indicate that the primary austenite precipitation zone of lost-foam casting is slightly larger than that of green sand casting. At the same time, the solid fraction(f_s) of the dendrite coherency points in lost-foam casting is greater than that in the green sand casting. Therefore, from these two points, lost-foam casting is more preferable for reduction of shrinkage and mechanical burntin sand tendency of the hypoeutectic gray cast iron. Due to the fact that the solidification process(from the surface to center) at primary austenite growth area in the lost-foam cylinder sample lags behind that in the green sand casting, the mushy solidification tendency of lost-foam casting is greater and the solidification time is longer.

Influence of lateral initial pressure on axisymmetric wave propagation in hollow cylinder based on first power hypo-elastic model

Influence of identical applied initial pressures on the radial surfaces of a hollow cylinder which is compose of materials with first power hypo-elastic constitutive model was investigated.The basic equations of the problem were built up based on the framework of piecewise homogeneous body model with the use of three-dimensional linearized theory of elastic waves in initially stressed bodies(TLTEWISB).With the method proposed previously,this problem was then solved numerically.Moreover,the dispersion group velocity of the lowest order mode with different initial pressures was also studied.It can be concluded that the initial pressure and the geometry parameters will induce considerable changes of different degrees in dispersive relation between phase velocity and wave number in opposite trend(positive in initial pressure and negative in thickness).

Lipopolysaccharide induced hyper- and hypo-responsiveness in macrophage cell lines

Objective: To build a cell model of LPS-induced hyper- and hypo-responsiveness in macrophage cells .Methods: Macrophage cell line RAW264.7 was pre-cultured with or without 10 ng/ml LPS for 18 h, then challenged with lipopolysaccharide(LPS), or MDP, Zymosan, PAF, FMLP, PMA for 24 h.The levels of TNF-α , IL-1, IL-6, IL-10 , NO and O-2 were measured.Results: LPS pretreatment markedly inhibited TNF-α NO and IL-6 production, but increased IL-1, IL-10 and O-2 release to LPS challenge.LPS pretreatment also altered macrophage responsiveness to the other stimuli.Conclusion: LPS can induce hyper- and hypo-responsiveness simultaneously in the macrophage cell lines.Changes in macrophage responsiveness depend on stimuli and effectors which are measured.

Development Strategies of Hypo-cities in Transportation Integration in Economic Regions

This paper attempts to analyze the functions of hypo-cities in the context of regional economic integration and further studies how hypo-cities with different characteristics exploit their advantages to the full,putting forward the development strategy of hypo-cities in the transportation integration.

上三角模算子矩阵的EP和hypo-EP性

研究了Hilbert C^(*)-模上hypo-EP和EP模算子矩阵,利用空间分解法,得到了上三角模算子矩阵的Moore-Penrose逆.进一步得到了上三角模算子矩阵是hypo-EP和EP的充分必要条件.作为应用,给出了上三角Hamilton模算子是hypo-EP和EP的充分必要条件.

Inter-Fraction Analysis of One Week Hypo-Fractionation of Deep Inspiration Breath Hold (DIBH) Technique for Left Sided Breast Cancer Radiation Treatment

The aim of this study was to investigate the inter-fraction variations, patient comfort and knowledge at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH). The differences in set-up that occurred between treatment sessions for the left sided breast patients were observed and recorded. Measurements of routine set-up variation for 24 patients were performed by matching the cone beam computed tomography (CBCT) and the planning computed tomography (CT). Scans of all five fractions per patient were used to quantify the setup variations with standard deviation (SD) in all the three directions (anterior posterior, left right, and superior inferior). The patients DIBH comfort and knowledge was also evaluated. The average translational errors for the anterior posterior (AP, z), left-right (LR, x), and Superior-inferior (SI, y) directions were 0.40 cm, 0.40 cm, and 0.40 cm, respectively. The translation variation of the three directions showed statistical significance (P < 0.05). On comfort and knowledge investigation, among all participants, 80% moderately agreed that the therapist’s instructions for operating the deep inspiration breath hold (DIBH) technique were easy to understand, and 63.33% indicated that their comfort with the DIBH technique was neutral or average. The inter-fraction variations in patients with left-sided breast cancer were qualitatively analyzed. Significant shifts between CBCT and planning CT images were observed. The daily treatment verification could assist accurate dose delivery.

大体积脑转移瘤大分割后程缩野放疗的剂量学及临床疗效分析

目的探讨大分割后程缩野放疗对大体积脑转移瘤患者的剂量学及其临床疗效分析。方法收集20例病灶体积6~20 cm^(3)、病灶数目1~4个且行大分割后程缩野放疗的脑转移瘤患者资料。脑部病灶处方剂量为52.5 Gy/3.5 Gy/15 f。治疗10次后复查颅脑增强MRI评估疗效、若肿瘤退缩明显重新勾画靶区完成后程放疗。评估不缩野放疗计划(Plan1)和后程缩野放疗计划下(Plan2)脑组织及其他危及器官剂量学参数变化、后程计划缩瘤率、近期疗效(疗后2~3个月评估近期疗效)。结果后程缩野放疗中脑组织及危及器官的辐射剂量都有下降。且后程缩野时平均缩瘤率为41.76%,3个月ORR为90.5%,6个月LCR为100%。结论大分割后程缩野放疗缩瘤率高,能有效减少正常组织剂量学参数值,对大体积病灶局部控制率好,近期疗效佳。

Relationship between Job Stress and Hypo-high-density Lipoproteinemia of Chinese Workers in Shanghai： The Rosai Karoshi Study

Background：Karoshi,or death due to overwork,has now become a serious social problem in China.Worsening of cardiovascular risks by stress might initiate karoshi.Many studies have examined the relationship between job stress and obesity,hypertension,and type 2 diabetes mellitus,but less evidence exists for dyslipidemia like hypo-high-density lipoproteinemia （hypo-HDL）.The aim of this study was to investigate the relationship between job stress and hypo-HDL of Chinese workers in Shanghai.Methods：We studied 2219 Chinese workers in Shanghai,who participated in the Japan-China cooperative study for the prevention of karoshi.A questionnaire was administered to examine the lifestyle characteristics,job category,weekly working hours,and job stress.Job demand and job control were quantified using the National Institute for Occupational Safety and Health questionnaire.Modified job strain measure was defined by the combination of low job control and high demand.Hypo-HDL was defined as plasma high-density lipoprotein cholesterol concentration of〈1.04 mmol/L （40 mg/dl）.Multivariate logistic regression analysis was performed for hypo-HDL as a dependent variable.Results：Modified job strain was not related to hypo-HDL either in men or women.In men,multivariate adjusted odds ratio （OR） for having hypo-HDL was significantly higher in the lowest job control tertile compared with the highest job control tertile （OR =1.39,95% confidence interval [CI] 1.03-1.87,P =0.034）.In the same model,a similar trend was observed for women,but it did not reach a statistically significant level （OR =1.51,95% CI,0.88-2.56,P =0.132）.Conclusion：A low level of job control but not modified job strain was significantly related to higher prevalence ofhypo-HDL of Chinese workers in Shanghai.

非酮症高血糖相关癫痫和视觉异常伴皮质下T_(2)低信号1例报告及文献复习

非酮症高血糖(Non-ketotic hyperglycemia,NKH)是一种临床综合征,包括高血糖症、血清高渗性和细胞内脱水,很少或没有酮症酸中毒。NKH的神经系统表现多种多样,涉及癫痫样发作和视觉异常。既往已报道NKH相关癫痫发作后皮质下T_(2)低信号作为其特征性影像征[1],其对癫痫发作病因具有提示意义。本文报道1例癫痫样发作频发,以视力受损为首发临床表现,既往2型糖尿病,血糖控制不佳,影像表现为枕叶皮质弥散受限,皮质下T_(2)低信号,抗癫痫及降糖治疗后发作停止,复查影像皮质下T_(2)低信号消退,支持NKH相关癫痫和视觉异常。为提高对NKH相关癫痫和视觉异常的临床和影像学认识,对其进行文献回顾。

2008年攀枝花6.1级地震序列精定位

利用四川和云南区域数字地震台网震相到时资料,并结合Hypo2000＋Hypo DD对2008年8月30日攀枝花MS6.1地震序列进行了定位。定位结果表明,地震序列的震中在空间上呈近SN向展布,余震密集区长度约为30km,主震震源深度约为14km。序列深度的分布范围主要为0~4、5~20km,而4~5km范围显示为明显的少震层。沿序列长轴的深度剖面显示,余震区中段存在1个不规则的少震的＂空区＂,为1955年634级地震的破裂区,该地震发生在空区的南端。分析认为,2008年8月30日攀枝花MS6.1地震是因汶川8.0级地震后的应力调整造成未破裂的小凹凸体发生破裂所致。余震密集分布区沿垂直于破裂长轴的两个剖面则显示了在其北端地震震源分布更深,且断层面向NW倾斜,与已知的红格断裂的倾向一致。

川滇菱形块体东边界地震精定位

选用四川及云南地震台站资料,采用多阶段地震定位法(Hypo2000+Velest+HypoDD),对四川境内川滇菱形块体东边界的道孚南至巧家段2010年1月1日~2014年12月31日7787次地震进行了精定位。精定位后,震源位置精度明显提高,震中分布与地震断裂带线性展布较一致。定位结果显示,鲜水河断裂带东南段地震分布相对密集,鲜水河南段与安宁河断裂带、小金河断裂带及以东的大凉山断裂带交叉区域相对密集。深度剖面图沿活动断裂带地震活动分段活动特征明显,横跨鲜水河、安宁河和大凉山等断裂的剖面呈现出石棉附近多断裂交汇处的断层间复杂的相互作用,地震明显分为深、浅两丛。15~20km深度范围地震非常稀少,这与朱艾斓提出的14~19km塑性流变的层厚和位置较一致。