Noise removal routines (destriping) were performed on Landsat ETM+ data as adjustments for atmospheric and distortion factors, prior to further image enhancement and interpretation. The image enhancement techniques w...Noise removal routines (destriping) were performed on Landsat ETM+ data as adjustments for atmospheric and distortion factors, prior to further image enhancement and interpretation. The image enhancement techniques were contrast stretching, density slicing, spatial filtering, Fourier analysis, brightness inversion, band combinations, and band ratioing. It has been revealed that, owing to the presence of gossans at Paishanlou, the mixture of iron oxide and clay minerals affects the spectral reflectance in satellite data. The mineral and hydrothermal composite images with band ratios 5/7+5/4+3/1 RGB and 5/7+3/1+4/3 RGB, respectively, yielded the best results for their sensitivity to lithologic variables, and lack of statistical redundancy. Ratio 3/1 clearly highlighted ferric (Fe 3+ ) iron; 5/4 depicted ferrous (Fe 2+ ) iron, and 5/7 depicted clays, carbonates, and hydroxyl bearing minerals. Vegetation was also successfully discriminated by ratio 5/7. Finally, coupled with field surveys, petrographical and geochemical data, the observed anomalies led to the discovery of three new sites, which are gold mineralized. The prime objective of this study was to map supergene and/or hypogene signatures in the gold mineralized areas using Landsat ETM+ data at Paishanlou.展开更多
Seven years after the discovery of the chemoautotrophic sulfidic groundwater site of the Ayyalon cave, its macrofauna can be fully reviewed. It consists of six endemic stygobiont and troglo-biont crustaceans and other...Seven years after the discovery of the chemoautotrophic sulfidic groundwater site of the Ayyalon cave, its macrofauna can be fully reviewed. It consists of six endemic stygobiont and troglo-biont crustaceans and other arthropods and two species still with unclear status. The taxonomic list is followed by brief discussions on the systematics of the species as well as by a few comments concerning the eventual broader zoogeographical and speleological implications of the Ayyalon faunistic findings, as they appeared in literature.展开更多
The Nahran area is located in the Northeast of Zanjan in the Northwest of Iran. This area with 20,000 km2 is part of the Tarom volcanic-plutonic zone which lies between the longitudes 49°7'7.8"E and 36&#...The Nahran area is located in the Northeast of Zanjan in the Northwest of Iran. This area with 20,000 km2 is part of the Tarom volcanic-plutonic zone which lies between the longitudes 49°7'7.8"E and 36°41'25.74"E near to the Nahran village. The Nahran altered zone is part of large-scale syncline, which is oriented from Sirdan to Altinkosh with an axial length of 9 km. A systematic study of petrographical and geochemical data of Nahran samples reveals they are andesite, trachyandesite to dacite composition and have metaluminous to peraluminous and calc-alkaline affinity. Four alteration zones of propylitic, medium and advanced argillic and silicific zones could be identified in the area. According to our finding, combination of both supergene and hypogene process has an effective role in the development of alteration in the Nahran alteration zone.展开更多
甲状旁腺素能增加人体骨密度和骨强度,是治疗骨质疏松症最有效的多肽类药物之一,但至今缺乏具有相应功能的小分子药物。根据计算机辅助药物设计原理,采用Discovery Studio 2.5软件包,以14个甲状旁腺素(PTH)受体激动剂及其突变类似物为...甲状旁腺素能增加人体骨密度和骨强度,是治疗骨质疏松症最有效的多肽类药物之一,但至今缺乏具有相应功能的小分子药物。根据计算机辅助药物设计原理,采用Discovery Studio 2.5软件包,以14个甲状旁腺素(PTH)受体激动剂及其突变类似物为训练集,利用活性构象限制的方法,采用HypoGen算法构建出具有活性预测功能的3D药效团模型。其中最好的药效团模型含有1个阳离子基团(PI),3个疏水中心(H)和1个氢键供体(HBD)。同时应用该模型成功预测出16个测试集分子的活性,经交叉验证表明该模型达到95%的置信水平,具有良好的活性预测能力。该药效团可以用于后续抗骨质疏松症小分子药物的筛选,指导相应的药物优化,同时所采用的限制构象的药效团生产方法为基于多肽的药物设计提供了一个新的思路。展开更多
文摘Noise removal routines (destriping) were performed on Landsat ETM+ data as adjustments for atmospheric and distortion factors, prior to further image enhancement and interpretation. The image enhancement techniques were contrast stretching, density slicing, spatial filtering, Fourier analysis, brightness inversion, band combinations, and band ratioing. It has been revealed that, owing to the presence of gossans at Paishanlou, the mixture of iron oxide and clay minerals affects the spectral reflectance in satellite data. The mineral and hydrothermal composite images with band ratios 5/7+5/4+3/1 RGB and 5/7+3/1+4/3 RGB, respectively, yielded the best results for their sensitivity to lithologic variables, and lack of statistical redundancy. Ratio 3/1 clearly highlighted ferric (Fe 3+ ) iron; 5/4 depicted ferrous (Fe 2+ ) iron, and 5/7 depicted clays, carbonates, and hydroxyl bearing minerals. Vegetation was also successfully discriminated by ratio 5/7. Finally, coupled with field surveys, petrographical and geochemical data, the observed anomalies led to the discovery of three new sites, which are gold mineralized. The prime objective of this study was to map supergene and/or hypogene signatures in the gold mineralized areas using Landsat ETM+ data at Paishanlou.
文摘Seven years after the discovery of the chemoautotrophic sulfidic groundwater site of the Ayyalon cave, its macrofauna can be fully reviewed. It consists of six endemic stygobiont and troglo-biont crustaceans and other arthropods and two species still with unclear status. The taxonomic list is followed by brief discussions on the systematics of the species as well as by a few comments concerning the eventual broader zoogeographical and speleological implications of the Ayyalon faunistic findings, as they appeared in literature.
文摘The Nahran area is located in the Northeast of Zanjan in the Northwest of Iran. This area with 20,000 km2 is part of the Tarom volcanic-plutonic zone which lies between the longitudes 49°7'7.8"E and 36°41'25.74"E near to the Nahran village. The Nahran altered zone is part of large-scale syncline, which is oriented from Sirdan to Altinkosh with an axial length of 9 km. A systematic study of petrographical and geochemical data of Nahran samples reveals they are andesite, trachyandesite to dacite composition and have metaluminous to peraluminous and calc-alkaline affinity. Four alteration zones of propylitic, medium and advanced argillic and silicific zones could be identified in the area. According to our finding, combination of both supergene and hypogene process has an effective role in the development of alteration in the Nahran alteration zone.
文摘甲状旁腺素能增加人体骨密度和骨强度,是治疗骨质疏松症最有效的多肽类药物之一,但至今缺乏具有相应功能的小分子药物。根据计算机辅助药物设计原理,采用Discovery Studio 2.5软件包,以14个甲状旁腺素(PTH)受体激动剂及其突变类似物为训练集,利用活性构象限制的方法,采用HypoGen算法构建出具有活性预测功能的3D药效团模型。其中最好的药效团模型含有1个阳离子基团(PI),3个疏水中心(H)和1个氢键供体(HBD)。同时应用该模型成功预测出16个测试集分子的活性,经交叉验证表明该模型达到95%的置信水平,具有良好的活性预测能力。该药效团可以用于后续抗骨质疏松症小分子药物的筛选,指导相应的药物优化,同时所采用的限制构象的药效团生产方法为基于多肽的药物设计提供了一个新的思路。
