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Progress of CACNA1S Gene and Hypokalemic Periodic Paralysis
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作者 王雪 任守文 刘红林 《Animal Husbandry and Feed Science》 CAS 2009年第2期18-21,共4页
CACNA1 S gene is the gene encoding L-type calcium channel αa-subunit. CACNA1 S gene mutations can cause hypokalemic periodic pa- ralysis (HOKPP). The related research speculated that CACNA1 S gene was the candidate... CACNA1 S gene is the gene encoding L-type calcium channel αa-subunit. CACNA1 S gene mutations can cause hypokalemic periodic pa- ralysis (HOKPP). The related research speculated that CACNA1 S gene was the candidate genes which affect meat quality traits. In the present ar- ticle, the biological characteristics of CACNA1 S gene, structure, genetic diseases and the research development were respectively reviewed so as to provide a reference for further research. 展开更多
关键词 CACNA1 S gene L-type calcium channel α1-subunit Human hypokalemic periodic paralysis
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Rhabdomyolysis following severe hypokalemia caused by familial hypokalemic periodic paralysis 被引量:6
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作者 Young-Lee Jung Jae-Young Kang 《World Journal of Clinical Cases》 SCIE 2017年第2期56-60,共5页
Rhabdomyolysis continues to appear with increasing frequency and represents a medical emergency requiring rapid appropriate treatment. One of the unusual causes of nontraumatic rhabdomyolysis is hypokalemic periodic p... Rhabdomyolysis continues to appear with increasing frequency and represents a medical emergency requiring rapid appropriate treatment. One of the unusual causes of nontraumatic rhabdomyolysis is hypokalemic periodic paralysis without secondary causes. Primary hypokalemic periodic paralysis is a rare genetic disease characterized by episodic attacks of muscle weakness due to decreases in serum potassium. A 30-year-old woman who had 3 episodic attacks of hypokalemic periodic paralysis was admitted in emergency room with sudden onset symmetrical muscle weakness. After several hours, she started to complain myalgia and severe ache in both calves without any changes. Laboratory test showed markedly elevated creatine phosphokinase, lactic dehydrogenase levels with hypokalemia, rhabdomyolysis resulting from hypokalemia was diagnosed. Here, we report an unusual case of rhabdomyolysis caused by severe hypokalemia, which was suggested a result of familial hypokalemic periodic paralysis. 展开更多
关键词 RHABDOMYOLYSIS HYPOKALEMIA FAMILIAL hypokalemic PERIODIC PARALYSIS
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Application of Clustering-based Decision Tree in the Screening of Maize Germplasm 被引量:2
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作者 王斌 《Agricultural Science & Technology》 CAS 2011年第10期1449-1452,共4页
[Objective] This paper aims to construct an improved fuzzy decision tree which is based on clustering,and researches into its application in the screening of maize germplasm.[Method] A new decision tree algorithm base... [Objective] This paper aims to construct an improved fuzzy decision tree which is based on clustering,and researches into its application in the screening of maize germplasm.[Method] A new decision tree algorithm based upon clustering is adopted in this paper,which is improved against the defect that traditional decision tree algorithm fails to handle samples of no classes.Meanwhile,the improved algorithm is also applied to the screening of maize varieties.Through the indices as leaf area,plant height,dry weight,potassium(K) utilization and others,maize seeds with strong tolerance of hypokalemic are filtered out.[Result] The algorithm in the screening of maize germplasm has great applicability and good performance.[Conclusion] In the future more efforts should be made to compare improved the performance of fuzzy decision tree based upon clustering with the performance of traditional fuzzy one,and it should be applied into more realistic problems. 展开更多
关键词 FCM Decision tree based upon clustering Screening indices Tolerance of hypokalemic
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