Many engineering design problems are characterized by presence of several conflicting objectives. This requires efficient search of the feasible design region for optimal solutions which simultaneously satisfy multipl...Many engineering design problems are characterized by presence of several conflicting objectives. This requires efficient search of the feasible design region for optimal solutions which simultaneously satisfy multiple design objectives. Genetic algorithm optimization (GAO) is a powerful search technique with faster convergence rates than traditional evolutionary algorithms. This paper applies two GAO-based approaches to multi-objective engineering design and finds design variables through the feasible space. To demonstrate the utility of the proposed methods, the multi-objective design of an I-beam will be presented.展开更多
This paper deals with the optimality conditions and dual theory of multi-objective programming problems involving generalized convexity. New classes of generalized type-I functions are introduced for arcwise connected...This paper deals with the optimality conditions and dual theory of multi-objective programming problems involving generalized convexity. New classes of generalized type-I functions are introduced for arcwise connected functions, and examples are given to show the existence of these functions. By utilizing the new concepts, several sufficient optimality conditions and Mond-Weir type duality results are proposed for non-differentiable multi-objective programming problem.展开更多
矛盾性失眠(paradoxical insomnia,Para-I)又被称为假性失眠(pseudoinsomnia)或失眠状态错觉(sleep state misperception,SSM)。这类患者通常主诉患有严重失眠,但缺乏睡眠紊乱的客观证据,日间功能受损情况与患者所述的睡眠缺失程度不成...矛盾性失眠(paradoxical insomnia,Para-I)又被称为假性失眠(pseudoinsomnia)或失眠状态错觉(sleep state misperception,SSM)。这类患者通常主诉患有严重失眠,但缺乏睡眠紊乱的客观证据,日间功能受损情况与患者所述的睡眠缺失程度不成比例。高估睡眠潜伏时间(sleeplatency,SL)、低估总睡眠时间(totalsleeptime,TST)是Para-I的主要特征。这种睡眠质量的错误评价妨碍了对睡眠障碍的诊断、严重程度及临床疗效的评估。Para-I的发病机制仍不清楚,可能与抑郁水平、焦虑水平、人格特征、社会关系质量、大脑结构和功能的特殊改变有关。基于多导睡眠监测(polysomnography,PSG)的失眠相关研究发现,非快速眼动睡眠(non-rapideyemovementsleep,NREM睡眠)和快速眼动睡眠(rapideyemovementsleep,REM睡眠)的改变可能与失眠患者的主客观睡眠不一致程度有关。PSG是诊断睡眠障碍的重要手段。它可以通过同步监测脑电图(electroencephalogram,EEG)、肌电图(electromyogram,EMG)、眼动电图(electrooculogram,EOG)、口鼻气流、胸腹呼吸运动、血氧饱和度、心电图(electrocardiogram,ECG)、鼾声等多项参数对睡眠结构及相关的生理行为变化进行分析。近年来,越来越多的研究开始借助PSG对Para-I的睡眠EEG及治疗进行探索并取得了一定的进展。该文就Para-I的脑电特征和治疗的最新进展做一综述,以期为Para-I的精准治疗提供新的思路。展开更多
文摘Many engineering design problems are characterized by presence of several conflicting objectives. This requires efficient search of the feasible design region for optimal solutions which simultaneously satisfy multiple design objectives. Genetic algorithm optimization (GAO) is a powerful search technique with faster convergence rates than traditional evolutionary algorithms. This paper applies two GAO-based approaches to multi-objective engineering design and finds design variables through the feasible space. To demonstrate the utility of the proposed methods, the multi-objective design of an I-beam will be presented.
文摘This paper deals with the optimality conditions and dual theory of multi-objective programming problems involving generalized convexity. New classes of generalized type-I functions are introduced for arcwise connected functions, and examples are given to show the existence of these functions. By utilizing the new concepts, several sufficient optimality conditions and Mond-Weir type duality results are proposed for non-differentiable multi-objective programming problem.
文摘矛盾性失眠(paradoxical insomnia,Para-I)又被称为假性失眠(pseudoinsomnia)或失眠状态错觉(sleep state misperception,SSM)。这类患者通常主诉患有严重失眠,但缺乏睡眠紊乱的客观证据,日间功能受损情况与患者所述的睡眠缺失程度不成比例。高估睡眠潜伏时间(sleeplatency,SL)、低估总睡眠时间(totalsleeptime,TST)是Para-I的主要特征。这种睡眠质量的错误评价妨碍了对睡眠障碍的诊断、严重程度及临床疗效的评估。Para-I的发病机制仍不清楚,可能与抑郁水平、焦虑水平、人格特征、社会关系质量、大脑结构和功能的特殊改变有关。基于多导睡眠监测(polysomnography,PSG)的失眠相关研究发现,非快速眼动睡眠(non-rapideyemovementsleep,NREM睡眠)和快速眼动睡眠(rapideyemovementsleep,REM睡眠)的改变可能与失眠患者的主客观睡眠不一致程度有关。PSG是诊断睡眠障碍的重要手段。它可以通过同步监测脑电图(electroencephalogram,EEG)、肌电图(electromyogram,EMG)、眼动电图(electrooculogram,EOG)、口鼻气流、胸腹呼吸运动、血氧饱和度、心电图(electrocardiogram,ECG)、鼾声等多项参数对睡眠结构及相关的生理行为变化进行分析。近年来,越来越多的研究开始借助PSG对Para-I的睡眠EEG及治疗进行探索并取得了一定的进展。该文就Para-I的脑电特征和治疗的最新进展做一综述,以期为Para-I的精准治疗提供新的思路。