Underground pipeline networks constitute a major component of urban infrastructure,and thus,it is imperative to have an efficient mechanism to manage them.This study introduces a secondary development system to effici...Underground pipeline networks constitute a major component of urban infrastructure,and thus,it is imperative to have an efficient mechanism to manage them.This study introduces a secondary development system to efficiently model underground pipeline networks,using the building information modeling(BIM)-based software Revit.The system comprises separate pipe point and tubulation models.Using a Revit application programming interface(API),the spatial position and attribute data of the pipe points are extracted from a pipeline database,and the corresponding tubulation data are extracted from a tubulation database.Using the Family class in Revit API,the cluster in the self-built library of pipe point is inserted into the spatial location and the attribute data is added;in the same way,all pipeline instances in the pipeline system are created.The extension and localization of the model accelerated the modeling speed.The system was then used in a real construction project.The expansion of the model database and rapid modeling made the application of BIM technology in three-dimensional visualization of underground pipeline networks more convenient.Furthermore,it has applications in pipeline engineering construction and management.展开更多
The lithofacies classification is essential for oil and gas reservoir exploration and development.The traditional method of lithofacies classification is based on"core calibration logging"and the experience ...The lithofacies classification is essential for oil and gas reservoir exploration and development.The traditional method of lithofacies classification is based on"core calibration logging"and the experience of geologists.This approach has strong subjectivity,low efficiency,and high uncertainty.This uncertainty may be one of the key factors affecting the results of 3 D modeling of tight sandstone reservoirs.In recent years,deep learning,which is a cutting-edge artificial intelligence technology,has attracted attention from various fields.However,the study of deep-learning techniques in the field of lithofacies classification has not been sufficient.Therefore,this paper proposes a novel hybrid deep-learning model based on the efficient data feature-extraction ability of convolutional neural networks(CNN)and the excellent ability to describe time-dependent features of long short-term memory networks(LSTM)to conduct lithological facies-classification experiments.The results of a series of experiments show that the hybrid CNN-LSTM model had an average accuracy of 87.3%and the best classification effect compared to the CNN,LSTM or the three commonly used machine learning models(Support vector machine,random forest,and gradient boosting decision tree).In addition,the borderline synthetic minority oversampling technique(BSMOTE)is introduced to address the class-imbalance issue of raw data.The results show that processed data balance can significantly improve the accuracy of lithofacies classification.Beside that,based on the fine lithofacies constraints,the sequential indicator simulation method is used to establish a three-dimensional lithofacies model,which completes the fine description of the spatial distribution of tight sandstone reservoirs in the study area.According to this comprehensive analysis,the proposed CNN-LSTM model,which eliminates class imbalance,can be effectively applied to lithofacies classification,and is expected to improve the reality of the geological model for the tight sandstone reservoirs.展开更多
This work presents an efficient method for volume rendering of glioma tumors from segmented 2D MRI Datasets with user interactive control, by replacing manual segmentation required in the state of art methods. The mos...This work presents an efficient method for volume rendering of glioma tumors from segmented 2D MRI Datasets with user interactive control, by replacing manual segmentation required in the state of art methods. The most common primary brain tumors are gliomas, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Tumor portions were automatically segmented from 2D MR images using morphological filtering techniques. These segmented tumor slices were propagated and modeled with the software package. The 3D modeled tumor consists of gray level values of the original image with exact tumor boundary. Axial slices of FLAIR and T2 weighted images were used for extracting tumors. Volumetric assessment of tumor volume with manual segmentation of its outlines is a time-consuming process and is prone to error. These defects are overcome in this method. Authors verified the performance of our method on several sets of MRI scans. The 3D modeling was also done using segmented 2D slices with the help of medical software package called 3D DOCTOR for verification purposes. The results were validated with the ground truth models by the Radiologist.展开更多
This paper presents an experimentally validated weld joint shape and dimensions predictive 3D modeling for low carbon galvanized steel in butt-joint configurations. The proposed modelling approach is based on metallur...This paper presents an experimentally validated weld joint shape and dimensions predictive 3D modeling for low carbon galvanized steel in butt-joint configurations. The proposed modelling approach is based on metallurgical transformations using temperature dependent material properties and the enthalpy method. Conduction and keyhole modes welding are investigated using surface and volumetric heat sources, respectively. Transition between the heat sources is carried out according to the power density and interaction time. Simulations are carried out using 3D finite element model on commercial software. The simulation results of the weld shape and dimensions are validated using a structured experimental investigation based on Taguchi method. Experimental validation conducted on a 3 kW Nd: YAG laser source reveals that the modelling approach can provide not only a consistent and accurate prediction of the weld characteristics under variable welding parameters and conditions but also a comprehensive and quantitative analysis of process parameters effects. The results show great concordance between predicted and measured values for the weld joint shape and dimensions.展开更多
Mobile laser scanning(MLS)systems mainly comprise laser scanners and mobile mapping platforms.Typical MLS systems can acquire three-dimensional point clouds with 1-10cm point spacings at a normal driving or walking sp...Mobile laser scanning(MLS)systems mainly comprise laser scanners and mobile mapping platforms.Typical MLS systems can acquire three-dimensional point clouds with 1-10cm point spacings at a normal driving or walking speed in streets or indoor environments.The efficiency and stability of these systems make them extremely useful for application in three-dimensional urban modeling.This paper reviews the latest advances of the LiDAR-based mobile mapping system(MMS)point cloud in the field of 3D modeling,including LiDAR simultaneous localization and mapping,point cloud registration,feature extraction,object extraction,semantic segmentation,and processing using deep learning.Furthermore,typical urban modeling applications based on MMS are also discussed.展开更多
Three-dimensional(3D)modeling is an important topic in computer graphics and computer vision.In recent years,the introduction of consumer-grade depth cameras has resulted in profound advances in 3D modeling.Starting w...Three-dimensional(3D)modeling is an important topic in computer graphics and computer vision.In recent years,the introduction of consumer-grade depth cameras has resulted in profound advances in 3D modeling.Starting with the basic data structure,this survey reviews the latest developments of 3D modeling based on depth cameras,including research works on camera tracking,3D object and scene reconstruction,and high-quality texture reconstruction.We also discuss the future work and possible solutions for 3D modeling based on the depth camera.展开更多
Because of good quality of compressive resistance, the hyperbolic arch dam is being increasingly applied to engineering projects. In order to satisfy the needs of compressive resistance under the conditions of high wa...Because of good quality of compressive resistance, the hyperbolic arch dam is being increasingly applied to engineering projects. In order to satisfy the needs of compressive resistance under the conditions of high water pressure, a stress analysis is required for the dam. During the stress analysis process however, due to the complexity of the three-dimensional modeling, it is very hard to form a model. Therefore, the stress analysis process is a barrier for the arch dam. In this article, based on the research of the new line-type arch dam, a mathematical model in different degree of convexity conditions of the dam is established; using the C + + language program, a computer three-dimensional model simulation is realized on AutoCAD. The accurate three-dimensional model is providing a finite element optimization design of the involute hyperbolic arch dam for the next step.展开更多
In the last issue,two case reports separately present examples of the extremely rare and complex congenital heart diseases that show concordant atrioventricular connections to the L-looped ventricles in the presence o...In the last issue,two case reports separately present examples of the extremely rare and complex congenital heart diseases that show concordant atrioventricular connections to the L-looped ventricles in the presence of situs solitus.Both cases highlight that the relationship between the two ventricles within the ventricular mass is not always harmonious with the given atrioventricular connection.Such disharmony between the connections and relationships requires careful assessment of the three basic facets of cardiac building blocks,namely their morphology,the relationship of their component parts,and their connections with the adjacent segments.3D imaging and printing can now facilitate an otherwise difficult diagnosis in such complex situations.Rotation of either the 3D images or the models permit accurate assessment of the ventricular topologic pattern by creating the right ventricular en-face septal view,thus facilitating placement of the observer’s hands.As we now emphasize,an alternative approach,which might prove more attractive to imagers,is to rotate the ventricular mass to provide the ventricular apical view,thus permitting determination of the ventricular relationship without using the hands.展开更多
Interleukin-10 (IL-10) is an important cytokine that plays a pivotal role in natural and adaptive immune systems. However, in lower vertebrates, especially in teleost the receptor of this cytokine is still largely unk...Interleukin-10 (IL-10) is an important cytokine that plays a pivotal role in natural and adaptive immune systems. However, in lower vertebrates, especially in teleost the receptor of this cytokine is still largely unknown. This paper described the cloning and characterization of grass carp interleukin-10 receptor 1 (gcIL10R1) and the 3D structure of its extracellular domain was predicted. The gcIL10R1 cDNA included 180 bp5’ untranslated region (UTR), 870 bp3’ UTR and an open reading frame (ORF) of 1632 bp. The ORF was found to encode a 543 amino acid protein with a putative JAK1 binding site, one STAT3 binding site. The phylogenetic analysis clusters gcIL10R1 with other teleost IL10R1s but independently of the amphibian, avian and mammalian IL10R1s. The 3D structure of its extracellular domain was the first homology model of a fish IL10R1 that revealed a high similarity with its mammalian and avian counterparts.展开更多
Fusarium head blight (FHB) is a destructive disease of wheat and other cereals. FHB occurs in Europe, North America and around the world causing significant losses in production and endangers human and animal health. ...Fusarium head blight (FHB) is a destructive disease of wheat and other cereals. FHB occurs in Europe, North America and around the world causing significant losses in production and endangers human and animal health. In this article, we provide the strategic steps for the specific target selection for the phytopathogen system wheat-Fusarium graminearum. The economic impact of FHB leads to the need for innovation. Currently used fungicides have been shown to be effective over the years, but recently cereal infecting Fusaria have developed resistance. Our work presents a new perspective on target selection to allow the development of new fungicides. We developed an innovative approach combining both genomic analysis and molecular modeling to increase the discovery for new chemical compounds with both safety and low environmental impact. Our protein targets selection revealed 13 candidates with high specificity, essentiality and potentially assayable with a favorable accessibility to drug activity. Among them, three proteins: trichodiene synthase, endoglucanase-5 and ERG6 were selected for deeper structural analyses to identify new putative fungicides. Overall, the bioinformatics filtering for novel protein targets applied for agricultural purposes is a response to the demand for chemical crop protection. The availability of the genome, secretome and PHI-base allowed the enrichment of the search that combined experimental data in planta. The homology modeling and molecular dynamics simulations allowed the acquisition of three robust and stable conformers. From this step, approximately ten thousand compounds have been virtually screened against three candidates. Forty-five top-ranked compounds were selected from docking results as presenting better interactions and energy at the binding pockets and no toxicity. These compounds may act as inhibitors and lead to the development of new fungicides.展开更多
Internet of Vehicles (IoV) is a new system that enables individual vehicles to connect with nearby vehicles,people, transportation infrastructure, and networks, thereby realizing amore intelligent and efficient transp...Internet of Vehicles (IoV) is a new system that enables individual vehicles to connect with nearby vehicles,people, transportation infrastructure, and networks, thereby realizing amore intelligent and efficient transportationsystem. The movement of vehicles and the three-dimensional (3D) nature of the road network cause the topologicalstructure of IoV to have the high space and time complexity.Network modeling and structure recognition for 3Droads can benefit the description of topological changes for IoV. This paper proposes a 3Dgeneral roadmodel basedon discrete points of roads obtained from GIS. First, the constraints imposed by 3D roads on moving vehicles areanalyzed. Then the effects of road curvature radius (Ra), longitudinal slope (Slo), and length (Len) on speed andacceleration are studied. Finally, a general 3D road network model based on road section features is established.This paper also presents intersection and road section recognition methods based on the structural features ofthe 3D road network model and the road features. Real GIS data from a specific region of Beijing is adopted tocreate the simulation scenario, and the simulation results validate the general 3D road network model and therecognitionmethod. Therefore, thiswork makes contributions to the field of intelligent transportation by providinga comprehensive approach tomodeling the 3Droad network and its topological changes in achieving efficient trafficflowand improved road safety.展开更多
Adult-onset brain cancers,such as glioblastomas,are particularly lethal.People with glioblastoma multiforme(GBM)do not anticipate living for more than 15 months if there is no cure.The results of conventional treatmen...Adult-onset brain cancers,such as glioblastomas,are particularly lethal.People with glioblastoma multiforme(GBM)do not anticipate living for more than 15 months if there is no cure.The results of conventional treatments over the past 20 years have been underwhelming.Tumor aggressiveness,location,and lack of systemic therapies that can penetrate the blood–brain barrier are all contributing factors.For GBM treatments that appear promising in preclinical studies,there is a considerable rate of failure in phaseⅠandⅡclinical trials.Unfortunately,access becomes impossible due to the intricate architecture of tumors.In vitro,bioengineered cancer models are currently being used by researchers to study disease development,test novel therapies,and advance specialized medications.Many different techniques for creating in vitro systems have arisen over the past few decades due to developments in cellular and tissue engineering.Later-stage research may yield better results if in vitro models that resemble brain tissue and the blood–brain barrier are used.With the use of 3D preclinical models made available by biomaterials,researchers have discovered that it is possible to overcome these limitations.Innovative in vitro models for the treatment of GBM are possible using biomaterials and novel drug carriers.This review discusses the benefits and drawbacks of 3D in vitro glioblastoma modeling systems.展开更多
To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D mode...To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D modeling to DTs modeling is analyzed,as well as the current application of DTs modeling in various industries.The application of 3D DTs modeling in theelds of smartmanufacturing,smart ecology,smart transportation,and smart buildings in smart cities is analyzed in detail,and the current limitations are summarized.It is found that the 3D modeling technology in DTs has broad prospects for development and has a huge impact on all walks of life and even human lifestyles.At the same time,the development of DTs modeling relies on the development and support capabilities of mature technologies such as Big Data,Internet of Things,Cloud Computing,Articial Intelligence,and game technology.Therefore,although some results have been achieved,there are still limitations.This work aims to provide a good theoretical support for the further development of 3D DTs modeling.展开更多
This study used the stable and convergent Dufort-Frankel method to differentially discretize the diffusion equation of the ground-well transient electromagnetic secondary field.The absorption boundary condition of com...This study used the stable and convergent Dufort-Frankel method to differentially discretize the diffusion equation of the ground-well transient electromagnetic secondary field.The absorption boundary condition of complex frequency-shifted perfectly matched layer(CFS-PML)was used for truncation so that the low-frequency electromagnetic wave can be better absorbed at the model boundary.A typical three-dimensional(3D)homogeneous half-space model was established and a low-resistivity cube model was analyzed under the half-space condition.The response patterns and drivers of the low-resistivity cube model were discussed under the influence of a low-resistivity overburden.The absorption boundary conditions of CFS-PML significantly affected the low-frequency electromagnetic waves.For a low-resistivity cube around the borehole,its response curve exhibited a single-peak,and the extreme point of the curve corresponded to the center of the low-resistivity body.When the low-resistivity cube was directly below the borehole,the response curve showed three extreme values(two high and one low),with the low corresponding to the center of the low-resistivity body.The total field response of the low-resistivity overburden was stronger than that of the uniform half-space model due to the low-resistivity shielding effect of electromagnetic waves.When the receiving-transmitting distance gradually increased,the effect of the low-resistivity overburden was gradually weakened,and the response of the low-resistivity cube was strengthened.It was affected by the ratio of the overburden resistivity to the resistivity of the low-resistivity body.展开更多
LIDAR point cloud-based 3D object detection aims to sense the surrounding environment by anchoring objects with the Bounding Box(BBox).However,under the three-dimensional space of autonomous driving scenes,the previou...LIDAR point cloud-based 3D object detection aims to sense the surrounding environment by anchoring objects with the Bounding Box(BBox).However,under the three-dimensional space of autonomous driving scenes,the previous object detection methods,due to the pre-processing of the original LIDAR point cloud into voxels or pillars,lose the coordinate information of the original point cloud,slow detection speed,and gain inaccurate bounding box positioning.To address the issues above,this study proposes a new two-stage network structure to extract point cloud features directly by PointNet++,which effectively preserves the original point cloud coordinate information.To improve the detection accuracy,a shell-based modeling method is proposed.It roughly determines which spherical shell the coordinates belong to.Then,the results are refined to ground truth,thereby narrowing the localization range and improving the detection accuracy.To improve the recall of 3D object detection with bounding boxes,this paper designs a self-attention module for 3D object detection with a skip connection structure.Some of these features are highlighted by weighting them on the feature dimensions.After training,it makes the feature weights that are favorable for object detection get larger.Thus,the extracted features are more adapted to the object detection task.Extensive comparison experiments and ablation experiments conducted on the KITTI dataset verify the effectiveness of our proposed method in improving recall and precision.展开更多
A survey and evaluation was carried out on a potential granitoid quarry site in the locality of Linguésso (North West of Ivory Coast) with the aim of identifying and estimating the quantity of exploitable granite...A survey and evaluation was carried out on a potential granitoid quarry site in the locality of Linguésso (North West of Ivory Coast) with the aim of identifying and estimating the quantity of exploitable granite based on the electrical resistivity methods. The combination of electrical trailing, sounding and tomography techniques allowed the determination of the characteristics of the rock deposit, namely the electrical signature (between 19,259 Ωm and 86,316 Ωm), the extension (N90°), the rooting (between 0 and 45 m) and the fracturing (between N14° and N160°) of the granitic formation sought. The modeling resulted in an estimated mineable rock volume of 2,936,250 m<sup>3</sup> providing a production quantity of 7,927,875 tonnes.展开更多
Landslide is the second largest natural disaster after earthquake. It is of significance to study the evolution laws and failure mechanism of landslides based on its surface 3D deformation information. Based on the ra...Landslide is the second largest natural disaster after earthquake. It is of significance to study the evolution laws and failure mechanism of landslides based on its surface 3D deformation information. Based on the rainfall-triggered waste dump instability model test, we studied the failure mechanisms of the waste dump by integrating surface deformation and internal slope stress and proposed novel parameters for identifying landslide stability. We developed a noncontact measurement device, which can obtain millimeter-level 3D deformation data for surface scene in physical model test;Then we developed the similar materials and established a test model for a waste dump. Based on the failure characteristics of slope surface, internal stress of slope body and displacement contours during the whole process, we divided the slope instability process in model test into four stages: rainfall infiltration and surface erosion, shallow sliding, deep sliding, and overall instability. Based on the obtained surface deformation data, we calculated the volume change during slope instability process and compared it with the point displacement on slope surface. The results showed that the volume change can not only reflect the slow-ultra acceleration process of slope failure, but also fully reflect the above four stages and reduce the fluctuations caused by random factors. Finally, this paper proposed two stability identification parameters: the volume change rate above the slip surface and the relative velocity of volume change rate. According to the calculation of these two parameters in model test, they can be used for study the deformation and failure mechanism of slope stability.展开更多
In order to enhance modeling efficiency and accuracy,we utilized 3D laser point cloud data for indoor space modeling.Point cloud data was obtained with a 3D laser scanner and optimized with Autodesk Recap and Revit so...In order to enhance modeling efficiency and accuracy,we utilized 3D laser point cloud data for indoor space modeling.Point cloud data was obtained with a 3D laser scanner and optimized with Autodesk Recap and Revit software to extract geometric information about the indoor environment.Furthermore,we proposed a method for constructing indoor elements based on parametric components.The research outcomes of this paper will offer new methods and tools for indoor space modeling and design.The approach of indoor space modeling based on 3D laser point cloud data and parametric component construction can enhance modeling efficiency and accuracy,providing architects,interior designers,and decorators with a better working platform and design reference.展开更多
The microbiota-gut-brain axis(MGBA)has emerged as a key prospect in the bidirectional communication between two major organ systems:the brain and the gut.Homeostasis between the two organ systems allows the body to fu...The microbiota-gut-brain axis(MGBA)has emerged as a key prospect in the bidirectional communication between two major organ systems:the brain and the gut.Homeostasis between the two organ systems allows the body to function without disease,whereas dysbiosis has long-standing evidence of etiopathological conditions.The most common communication paths are the microbial release of metabolites,soluble neurotransmitters,and immune cells.However,each pathway is intertwined with a complex one.With the emergence of in vitro models and the popularity of three-dimensional(3D)cultures and Transwells,engineering has become easier for the scientific understanding of neurodegenerative diseases.This paper briefly retraces the possible communication pathways between the gut microbiome and the brain.It further elaborates on three major diseases:autism spectrum disorder,Parkinson’s disease,and Alzheimer’s disease,which are prevalent in children and the elderly.These diseases also decrease patients’quality of life.Hence,understanding them more deeply with respect to current advances in in vitro modeling is crucial for understanding the diseases.Remodeling of MGBA in the laboratory uses many molecular technologies and biomaterial advances.Spheroids and organoids provide a more realistic picture of the cell and tissue structure than monolayers.Combining them with the Transwell system offers the advantage of compartmentalizing the two systems(apical and basal)while allowing physical and chemical cues between them.Cutting-edge technologies,such as bioprinting and microfluidic chips,might be the future of in vitro modeling,as they provide dynamicity.展开更多
基金supported by a grant(No.14DZ2292800,http://www.greengeo.net/)from“Technology Service Platform of Civil Engineering”of Science and Technology Commission of Shanghai Municipality.
文摘Underground pipeline networks constitute a major component of urban infrastructure,and thus,it is imperative to have an efficient mechanism to manage them.This study introduces a secondary development system to efficiently model underground pipeline networks,using the building information modeling(BIM)-based software Revit.The system comprises separate pipe point and tubulation models.Using a Revit application programming interface(API),the spatial position and attribute data of the pipe points are extracted from a pipeline database,and the corresponding tubulation data are extracted from a tubulation database.Using the Family class in Revit API,the cluster in the self-built library of pipe point is inserted into the spatial location and the attribute data is added;in the same way,all pipeline instances in the pipeline system are created.The extension and localization of the model accelerated the modeling speed.The system was then used in a real construction project.The expansion of the model database and rapid modeling made the application of BIM technology in three-dimensional visualization of underground pipeline networks more convenient.Furthermore,it has applications in pipeline engineering construction and management.
基金supported by the Fundamental Research Funds for the Central Universities(Grant No.300102278402)。
文摘The lithofacies classification is essential for oil and gas reservoir exploration and development.The traditional method of lithofacies classification is based on"core calibration logging"and the experience of geologists.This approach has strong subjectivity,low efficiency,and high uncertainty.This uncertainty may be one of the key factors affecting the results of 3 D modeling of tight sandstone reservoirs.In recent years,deep learning,which is a cutting-edge artificial intelligence technology,has attracted attention from various fields.However,the study of deep-learning techniques in the field of lithofacies classification has not been sufficient.Therefore,this paper proposes a novel hybrid deep-learning model based on the efficient data feature-extraction ability of convolutional neural networks(CNN)and the excellent ability to describe time-dependent features of long short-term memory networks(LSTM)to conduct lithological facies-classification experiments.The results of a series of experiments show that the hybrid CNN-LSTM model had an average accuracy of 87.3%and the best classification effect compared to the CNN,LSTM or the three commonly used machine learning models(Support vector machine,random forest,and gradient boosting decision tree).In addition,the borderline synthetic minority oversampling technique(BSMOTE)is introduced to address the class-imbalance issue of raw data.The results show that processed data balance can significantly improve the accuracy of lithofacies classification.Beside that,based on the fine lithofacies constraints,the sequential indicator simulation method is used to establish a three-dimensional lithofacies model,which completes the fine description of the spatial distribution of tight sandstone reservoirs in the study area.According to this comprehensive analysis,the proposed CNN-LSTM model,which eliminates class imbalance,can be effectively applied to lithofacies classification,and is expected to improve the reality of the geological model for the tight sandstone reservoirs.
文摘This work presents an efficient method for volume rendering of glioma tumors from segmented 2D MRI Datasets with user interactive control, by replacing manual segmentation required in the state of art methods. The most common primary brain tumors are gliomas, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Tumor portions were automatically segmented from 2D MR images using morphological filtering techniques. These segmented tumor slices were propagated and modeled with the software package. The 3D modeled tumor consists of gray level values of the original image with exact tumor boundary. Axial slices of FLAIR and T2 weighted images were used for extracting tumors. Volumetric assessment of tumor volume with manual segmentation of its outlines is a time-consuming process and is prone to error. These defects are overcome in this method. Authors verified the performance of our method on several sets of MRI scans. The 3D modeling was also done using segmented 2D slices with the help of medical software package called 3D DOCTOR for verification purposes. The results were validated with the ground truth models by the Radiologist.
文摘This paper presents an experimentally validated weld joint shape and dimensions predictive 3D modeling for low carbon galvanized steel in butt-joint configurations. The proposed modelling approach is based on metallurgical transformations using temperature dependent material properties and the enthalpy method. Conduction and keyhole modes welding are investigated using surface and volumetric heat sources, respectively. Transition between the heat sources is carried out according to the power density and interaction time. Simulations are carried out using 3D finite element model on commercial software. The simulation results of the weld shape and dimensions are validated using a structured experimental investigation based on Taguchi method. Experimental validation conducted on a 3 kW Nd: YAG laser source reveals that the modelling approach can provide not only a consistent and accurate prediction of the weld characteristics under variable welding parameters and conditions but also a comprehensive and quantitative analysis of process parameters effects. The results show great concordance between predicted and measured values for the weld joint shape and dimensions.
文摘Mobile laser scanning(MLS)systems mainly comprise laser scanners and mobile mapping platforms.Typical MLS systems can acquire three-dimensional point clouds with 1-10cm point spacings at a normal driving or walking speed in streets or indoor environments.The efficiency and stability of these systems make them extremely useful for application in three-dimensional urban modeling.This paper reviews the latest advances of the LiDAR-based mobile mapping system(MMS)point cloud in the field of 3D modeling,including LiDAR simultaneous localization and mapping,point cloud registration,feature extraction,object extraction,semantic segmentation,and processing using deep learning.Furthermore,typical urban modeling applications based on MMS are also discussed.
基金National Natural Science Foundation of China(61732016).
文摘Three-dimensional(3D)modeling is an important topic in computer graphics and computer vision.In recent years,the introduction of consumer-grade depth cameras has resulted in profound advances in 3D modeling.Starting with the basic data structure,this survey reviews the latest developments of 3D modeling based on depth cameras,including research works on camera tracking,3D object and scene reconstruction,and high-quality texture reconstruction.We also discuss the future work and possible solutions for 3D modeling based on the depth camera.
基金Supported by Postgraduate Education Innovation Fund of Chongqing Jiaotong University
文摘Because of good quality of compressive resistance, the hyperbolic arch dam is being increasingly applied to engineering projects. In order to satisfy the needs of compressive resistance under the conditions of high water pressure, a stress analysis is required for the dam. During the stress analysis process however, due to the complexity of the three-dimensional modeling, it is very hard to form a model. Therefore, the stress analysis process is a barrier for the arch dam. In this article, based on the research of the new line-type arch dam, a mathematical model in different degree of convexity conditions of the dam is established; using the C + + language program, a computer three-dimensional model simulation is realized on AutoCAD. The accurate three-dimensional model is providing a finite element optimization design of the involute hyperbolic arch dam for the next step.
文摘In the last issue,two case reports separately present examples of the extremely rare and complex congenital heart diseases that show concordant atrioventricular connections to the L-looped ventricles in the presence of situs solitus.Both cases highlight that the relationship between the two ventricles within the ventricular mass is not always harmonious with the given atrioventricular connection.Such disharmony between the connections and relationships requires careful assessment of the three basic facets of cardiac building blocks,namely their morphology,the relationship of their component parts,and their connections with the adjacent segments.3D imaging and printing can now facilitate an otherwise difficult diagnosis in such complex situations.Rotation of either the 3D images or the models permit accurate assessment of the ventricular topologic pattern by creating the right ventricular en-face septal view,thus facilitating placement of the observer’s hands.As we now emphasize,an alternative approach,which might prove more attractive to imagers,is to rotate the ventricular mass to provide the ventricular apical view,thus permitting determination of the ventricular relationship without using the hands.
文摘Interleukin-10 (IL-10) is an important cytokine that plays a pivotal role in natural and adaptive immune systems. However, in lower vertebrates, especially in teleost the receptor of this cytokine is still largely unknown. This paper described the cloning and characterization of grass carp interleukin-10 receptor 1 (gcIL10R1) and the 3D structure of its extracellular domain was predicted. The gcIL10R1 cDNA included 180 bp5’ untranslated region (UTR), 870 bp3’ UTR and an open reading frame (ORF) of 1632 bp. The ORF was found to encode a 543 amino acid protein with a putative JAK1 binding site, one STAT3 binding site. The phylogenetic analysis clusters gcIL10R1 with other teleost IL10R1s but independently of the amphibian, avian and mammalian IL10R1s. The 3D structure of its extracellular domain was the first homology model of a fish IL10R1 that revealed a high similarity with its mammalian and avian counterparts.
文摘Fusarium head blight (FHB) is a destructive disease of wheat and other cereals. FHB occurs in Europe, North America and around the world causing significant losses in production and endangers human and animal health. In this article, we provide the strategic steps for the specific target selection for the phytopathogen system wheat-Fusarium graminearum. The economic impact of FHB leads to the need for innovation. Currently used fungicides have been shown to be effective over the years, but recently cereal infecting Fusaria have developed resistance. Our work presents a new perspective on target selection to allow the development of new fungicides. We developed an innovative approach combining both genomic analysis and molecular modeling to increase the discovery for new chemical compounds with both safety and low environmental impact. Our protein targets selection revealed 13 candidates with high specificity, essentiality and potentially assayable with a favorable accessibility to drug activity. Among them, three proteins: trichodiene synthase, endoglucanase-5 and ERG6 were selected for deeper structural analyses to identify new putative fungicides. Overall, the bioinformatics filtering for novel protein targets applied for agricultural purposes is a response to the demand for chemical crop protection. The availability of the genome, secretome and PHI-base allowed the enrichment of the search that combined experimental data in planta. The homology modeling and molecular dynamics simulations allowed the acquisition of three robust and stable conformers. From this step, approximately ten thousand compounds have been virtually screened against three candidates. Forty-five top-ranked compounds were selected from docking results as presenting better interactions and energy at the binding pockets and no toxicity. These compounds may act as inhibitors and lead to the development of new fungicides.
基金the National Natural Science Foundation of China(Nos.62272063,62072056 and 61902041)the Natural Science Foundation of Hunan Province(Nos.2022JJ30617 and 2020JJ2029)+4 种基金Open Research Fund of Key Lab of Broadband Wireless Communication and Sensor Network Technology,Nanjing University of Posts and Telecommunications(No.JZNY202102)the Traffic Science and Technology Project of Hunan Province,China(No.202042)Hunan Provincial Key Research and Development Program(No.2022GK2019)this work was funded by the Researchers Supporting Project Number(RSPD2023R681)King Saud University,Riyadh,Saudi Arabia.
文摘Internet of Vehicles (IoV) is a new system that enables individual vehicles to connect with nearby vehicles,people, transportation infrastructure, and networks, thereby realizing amore intelligent and efficient transportationsystem. The movement of vehicles and the three-dimensional (3D) nature of the road network cause the topologicalstructure of IoV to have the high space and time complexity.Network modeling and structure recognition for 3Droads can benefit the description of topological changes for IoV. This paper proposes a 3Dgeneral roadmodel basedon discrete points of roads obtained from GIS. First, the constraints imposed by 3D roads on moving vehicles areanalyzed. Then the effects of road curvature radius (Ra), longitudinal slope (Slo), and length (Len) on speed andacceleration are studied. Finally, a general 3D road network model based on road section features is established.This paper also presents intersection and road section recognition methods based on the structural features ofthe 3D road network model and the road features. Real GIS data from a specific region of Beijing is adopted tocreate the simulation scenario, and the simulation results validate the general 3D road network model and therecognitionmethod. Therefore, thiswork makes contributions to the field of intelligent transportation by providinga comprehensive approach tomodeling the 3Droad network and its topological changes in achieving efficient trafficflowand improved road safety.
文摘Adult-onset brain cancers,such as glioblastomas,are particularly lethal.People with glioblastoma multiforme(GBM)do not anticipate living for more than 15 months if there is no cure.The results of conventional treatments over the past 20 years have been underwhelming.Tumor aggressiveness,location,and lack of systemic therapies that can penetrate the blood–brain barrier are all contributing factors.For GBM treatments that appear promising in preclinical studies,there is a considerable rate of failure in phaseⅠandⅡclinical trials.Unfortunately,access becomes impossible due to the intricate architecture of tumors.In vitro,bioengineered cancer models are currently being used by researchers to study disease development,test novel therapies,and advance specialized medications.Many different techniques for creating in vitro systems have arisen over the past few decades due to developments in cellular and tissue engineering.Later-stage research may yield better results if in vitro models that resemble brain tissue and the blood–brain barrier are used.With the use of 3D preclinical models made available by biomaterials,researchers have discovered that it is possible to overcome these limitations.Innovative in vitro models for the treatment of GBM are possible using biomaterials and novel drug carriers.This review discusses the benefits and drawbacks of 3D in vitro glioblastoma modeling systems.
文摘To understand the current application and development of 3D modeling in Digital Twins(DTs),abundant literatures on DTs and 3D modeling are investigated by means of literature review.The transition process from 3D modeling to DTs modeling is analyzed,as well as the current application of DTs modeling in various industries.The application of 3D DTs modeling in theelds of smartmanufacturing,smart ecology,smart transportation,and smart buildings in smart cities is analyzed in detail,and the current limitations are summarized.It is found that the 3D modeling technology in DTs has broad prospects for development and has a huge impact on all walks of life and even human lifestyles.At the same time,the development of DTs modeling relies on the development and support capabilities of mature technologies such as Big Data,Internet of Things,Cloud Computing,Articial Intelligence,and game technology.Therefore,although some results have been achieved,there are still limitations.This work aims to provide a good theoretical support for the further development of 3D DTs modeling.
基金This work was supported by China Postdoctoral Science Foundation(No.2022M723391)the Science and Technology Innovation Project of Higher Education in Shanxi Province(No.2019L0754)+1 种基金the Central Guiding Local Science and Technology Development Fund Project(No.YDZJSX2021B021)Shanxi Province Basic Research Plan General Project(No.202203021221294).
文摘This study used the stable and convergent Dufort-Frankel method to differentially discretize the diffusion equation of the ground-well transient electromagnetic secondary field.The absorption boundary condition of complex frequency-shifted perfectly matched layer(CFS-PML)was used for truncation so that the low-frequency electromagnetic wave can be better absorbed at the model boundary.A typical three-dimensional(3D)homogeneous half-space model was established and a low-resistivity cube model was analyzed under the half-space condition.The response patterns and drivers of the low-resistivity cube model were discussed under the influence of a low-resistivity overburden.The absorption boundary conditions of CFS-PML significantly affected the low-frequency electromagnetic waves.For a low-resistivity cube around the borehole,its response curve exhibited a single-peak,and the extreme point of the curve corresponded to the center of the low-resistivity body.When the low-resistivity cube was directly below the borehole,the response curve showed three extreme values(two high and one low),with the low corresponding to the center of the low-resistivity body.The total field response of the low-resistivity overburden was stronger than that of the uniform half-space model due to the low-resistivity shielding effect of electromagnetic waves.When the receiving-transmitting distance gradually increased,the effect of the low-resistivity overburden was gradually weakened,and the response of the low-resistivity cube was strengthened.It was affected by the ratio of the overburden resistivity to the resistivity of the low-resistivity body.
基金This work was supported,in part,by the National Nature Science Foundation of China under grant numbers 62272236in part,by the Natural Science Foundation of Jiangsu Province under grant numbers BK20201136,BK20191401in part,by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)fund.
文摘LIDAR point cloud-based 3D object detection aims to sense the surrounding environment by anchoring objects with the Bounding Box(BBox).However,under the three-dimensional space of autonomous driving scenes,the previous object detection methods,due to the pre-processing of the original LIDAR point cloud into voxels or pillars,lose the coordinate information of the original point cloud,slow detection speed,and gain inaccurate bounding box positioning.To address the issues above,this study proposes a new two-stage network structure to extract point cloud features directly by PointNet++,which effectively preserves the original point cloud coordinate information.To improve the detection accuracy,a shell-based modeling method is proposed.It roughly determines which spherical shell the coordinates belong to.Then,the results are refined to ground truth,thereby narrowing the localization range and improving the detection accuracy.To improve the recall of 3D object detection with bounding boxes,this paper designs a self-attention module for 3D object detection with a skip connection structure.Some of these features are highlighted by weighting them on the feature dimensions.After training,it makes the feature weights that are favorable for object detection get larger.Thus,the extracted features are more adapted to the object detection task.Extensive comparison experiments and ablation experiments conducted on the KITTI dataset verify the effectiveness of our proposed method in improving recall and precision.
文摘A survey and evaluation was carried out on a potential granitoid quarry site in the locality of Linguésso (North West of Ivory Coast) with the aim of identifying and estimating the quantity of exploitable granite based on the electrical resistivity methods. The combination of electrical trailing, sounding and tomography techniques allowed the determination of the characteristics of the rock deposit, namely the electrical signature (between 19,259 Ωm and 86,316 Ωm), the extension (N90°), the rooting (between 0 and 45 m) and the fracturing (between N14° and N160°) of the granitic formation sought. The modeling resulted in an estimated mineable rock volume of 2,936,250 m<sup>3</sup> providing a production quantity of 7,927,875 tonnes.
基金funded by the National Key R&D Program of China (Grant No. 2021YFB3901402)the Fundamental Research Funds for the Central Universities (Project No. 2022CDJKYJH037)。
文摘Landslide is the second largest natural disaster after earthquake. It is of significance to study the evolution laws and failure mechanism of landslides based on its surface 3D deformation information. Based on the rainfall-triggered waste dump instability model test, we studied the failure mechanisms of the waste dump by integrating surface deformation and internal slope stress and proposed novel parameters for identifying landslide stability. We developed a noncontact measurement device, which can obtain millimeter-level 3D deformation data for surface scene in physical model test;Then we developed the similar materials and established a test model for a waste dump. Based on the failure characteristics of slope surface, internal stress of slope body and displacement contours during the whole process, we divided the slope instability process in model test into four stages: rainfall infiltration and surface erosion, shallow sliding, deep sliding, and overall instability. Based on the obtained surface deformation data, we calculated the volume change during slope instability process and compared it with the point displacement on slope surface. The results showed that the volume change can not only reflect the slow-ultra acceleration process of slope failure, but also fully reflect the above four stages and reduce the fluctuations caused by random factors. Finally, this paper proposed two stability identification parameters: the volume change rate above the slip surface and the relative velocity of volume change rate. According to the calculation of these two parameters in model test, they can be used for study the deformation and failure mechanism of slope stability.
基金supported by the Innovation and Entrepreneurship Training Program Topic for College Students of North China University of Technology in 2023.
文摘In order to enhance modeling efficiency and accuracy,we utilized 3D laser point cloud data for indoor space modeling.Point cloud data was obtained with a 3D laser scanner and optimized with Autodesk Recap and Revit software to extract geometric information about the indoor environment.Furthermore,we proposed a method for constructing indoor elements based on parametric components.The research outcomes of this paper will offer new methods and tools for indoor space modeling and design.The approach of indoor space modeling based on 3D laser point cloud data and parametric component construction can enhance modeling efficiency and accuracy,providing architects,interior designers,and decorators with a better working platform and design reference.
文摘The microbiota-gut-brain axis(MGBA)has emerged as a key prospect in the bidirectional communication between two major organ systems:the brain and the gut.Homeostasis between the two organ systems allows the body to function without disease,whereas dysbiosis has long-standing evidence of etiopathological conditions.The most common communication paths are the microbial release of metabolites,soluble neurotransmitters,and immune cells.However,each pathway is intertwined with a complex one.With the emergence of in vitro models and the popularity of three-dimensional(3D)cultures and Transwells,engineering has become easier for the scientific understanding of neurodegenerative diseases.This paper briefly retraces the possible communication pathways between the gut microbiome and the brain.It further elaborates on three major diseases:autism spectrum disorder,Parkinson’s disease,and Alzheimer’s disease,which are prevalent in children and the elderly.These diseases also decrease patients’quality of life.Hence,understanding them more deeply with respect to current advances in in vitro modeling is crucial for understanding the diseases.Remodeling of MGBA in the laboratory uses many molecular technologies and biomaterial advances.Spheroids and organoids provide a more realistic picture of the cell and tissue structure than monolayers.Combining them with the Transwell system offers the advantage of compartmentalizing the two systems(apical and basal)while allowing physical and chemical cues between them.Cutting-edge technologies,such as bioprinting and microfluidic chips,might be the future of in vitro modeling,as they provide dynamicity.