In basic homological algebra, the flat and injective dimensions of modules play an important and fundamental role. In this paper, the closely related IFP-flat and IFP-injective dimensions are introduced and studied. W...In basic homological algebra, the flat and injective dimensions of modules play an important and fundamental role. In this paper, the closely related IFP-flat and IFP-injective dimensions are introduced and studied. We show that IFP-fd(M) = IFP-id(M+) and IFP-fd(M+)=IFP-id(M) for any R-module M over any ring R. Let :Z-In (resp., "Zgv,~) he the class of all left (resp., right) R-modules of IFP-injective (resp., IFP-flat) dimension at most n. We prove that every right R-module has an IFn- preenvelope, (IFn,IF⊥n) is a perfect cotorsion theory over any ring R, and for any ring R with IFP-id(RR) 〈 n, (IIn,II⊥n) is a perfect cotorsion theory. This generalizes and improves the earlier work (J. Algebra 242 (2001), 447-459). Finally, some applications are given.展开更多
为促进水果生产健康发展,有效提高果品质量和经济效益,增加农民收入,推动水果生产向园区化、特色化和设施化发展,昆明市西山区农业局最近举办欧盟IFP(Integrated Fruit Production,果树综合管理)技术培训。昆明市农业科学院经作...为促进水果生产健康发展,有效提高果品质量和经济效益,增加农民收入,推动水果生产向园区化、特色化和设施化发展,昆明市西山区农业局最近举办欧盟IFP(Integrated Fruit Production,果树综合管理)技术培训。昆明市农业科学院经作所、西山区科信局、宜良雪峰生态园等从事果园生产管理的企业负责人、基层果树生产技术推广人员共26人参加了这次培训。展开更多
人源N-Myc结合蛋白(N-Myc interactor,Nmi)能在干扰素(interferon,IFN)诱导后高表达,并参与下游的JAK-STAT通路,且有抑制癌细胞增殖的功能.Nmi能够结合人干扰素结合蛋白35(interferon-induced protein 35,IFP35)并保护IFP35不被降解.本...人源N-Myc结合蛋白(N-Myc interactor,Nmi)能在干扰素(interferon,IFN)诱导后高表达,并参与下游的JAK-STAT通路,且有抑制癌细胞增殖的功能.Nmi能够结合人干扰素结合蛋白35(interferon-induced protein 35,IFP35)并保护IFP35不被降解.本研究构建了Nmi和IFP35的全长及N端截短体克隆,通过两种蛋白的共表达和GST pull down实验确定二者能够相互作用的区域,并进一步大量共表达和纯化了重组蛋白复合物.结合实验表明,与先前报道的两者通过C端串联的NID结构域相结合不同,两者的N端结构域都足以介导复合物形成.免疫荧光观察未经干扰素刺激的RAW264.7细胞,发现Nmi与IFP35共定位于细胞核内.免疫荧光观察Nmi在293A细胞中的分布特点,发现正常细胞中Nmi分布于细胞核内.如先前研究报道,干扰素诱导24h后,Nmi在胞质内形成颗粒状聚集,此时加入低浓度过氧化氢(H2O2)会使Nmi的亚细胞定位回到细胞核内,表明Nmi的亚细胞定位受到细胞氧化环境的影响.展开更多
基金supported by National Natural Science Foundation of China(10961021,11001222)
文摘In basic homological algebra, the flat and injective dimensions of modules play an important and fundamental role. In this paper, the closely related IFP-flat and IFP-injective dimensions are introduced and studied. We show that IFP-fd(M) = IFP-id(M+) and IFP-fd(M+)=IFP-id(M) for any R-module M over any ring R. Let :Z-In (resp., "Zgv,~) he the class of all left (resp., right) R-modules of IFP-injective (resp., IFP-flat) dimension at most n. We prove that every right R-module has an IFn- preenvelope, (IFn,IF⊥n) is a perfect cotorsion theory over any ring R, and for any ring R with IFP-id(RR) 〈 n, (IIn,II⊥n) is a perfect cotorsion theory. This generalizes and improves the earlier work (J. Algebra 242 (2001), 447-459). Finally, some applications are given.
文摘为促进水果生产健康发展,有效提高果品质量和经济效益,增加农民收入,推动水果生产向园区化、特色化和设施化发展,昆明市西山区农业局最近举办欧盟IFP(Integrated Fruit Production,果树综合管理)技术培训。昆明市农业科学院经作所、西山区科信局、宜良雪峰生态园等从事果园生产管理的企业负责人、基层果树生产技术推广人员共26人参加了这次培训。