Diabetic peripheral neuropathy(DPN)is one of the most common and intractable complications of diabetes mellitus.Its irritating symptoms,such as paresthesia,hyperalgesia and allodynia,can be causes of insomnia and de...Diabetic peripheral neuropathy(DPN)is one of the most common and intractable complications of diabetes mellitus.Its irritating symptoms,such as paresthesia,hyperalgesia and allodynia,can be causes of insomnia and depression;whereas its progression to more advanced stages can result in serious consequences,such as lower limb amputations and lethal arrhythmias.展开更多
基金supported by a Grant-in-aid for Scientific Research from the Ministry of Education,Science,Sports and Culture of Japan(grant number:25430056)
文摘Diabetic peripheral neuropathy(DPN)is one of the most common and intractable complications of diabetes mellitus.Its irritating symptoms,such as paresthesia,hyperalgesia and allodynia,can be causes of insomnia and depression;whereas its progression to more advanced stages can result in serious consequences,such as lower limb amputations and lethal arrhythmias.