目的:探讨老年髋部骨折手术患者实施超前镇痛联合多模式镇痛的效果及对IL-6、CRP水平的影响。方法:择取2019年1月-2020年1月笔者所在医院80例老年髋部骨折手术患者为研究对象,按照随机数字表法将其分为对照组和观察组,各40例。对照组实...目的:探讨老年髋部骨折手术患者实施超前镇痛联合多模式镇痛的效果及对IL-6、CRP水平的影响。方法:择取2019年1月-2020年1月笔者所在医院80例老年髋部骨折手术患者为研究对象,按照随机数字表法将其分为对照组和观察组,各40例。对照组实施常规硬膜外自控镇痛,观察组实施超前镇痛联合多模式镇痛。比较两组不同时间VAS评分及IL-6、CRP水平。结果:观察组术后1、24、72 h、1周VAS评分均低于对照组,差异有统计学意义(P<0.05)。观察组术前1 h、术后1、24、48 h IL-6、CRP水平均低于对照组,差异有统计学意义(P<0.05)。结论:老年髋部骨折手术患者实施超前镇痛联合多模式镇痛,可大幅减轻患者术后疼痛,减轻炎性反应,从而加快术后康复,值得临床参考借鉴。展开更多
Objective: To understand the application of echocardiography combined with blood SAA, IL-6, PCT, and CRP detection in the diagnosis and treatment of Kawasaki disease in children. Methods: 56 children with Kawasaki dis...Objective: To understand the application of echocardiography combined with blood SAA, IL-6, PCT, and CRP detection in the diagnosis and treatment of Kawasaki disease in children. Methods: 56 children with Kawasaki disease were selected as the study subjects as the treatment group, and 54 children with other diseases during the same period were selected as the control group. Echocardiography, blood SAA, IL-6, PCT and CRP were detected before and after treatment to observe the results of the two groups. A database was established to compare the changes of various indicators between the two groups, as well as the application value of each indicator in the clinical diagnosis and treatment of Kawasaki disease, and the pros and cons of the application of each indicator in the diagnosis and treatment of children with Kawasaki disease were analyzed, so as to provide a clearer early warning mechanism for the clinical diagnosis and treatment of children with Kawasaki disease. Results: There was no significant difference in the results of related imaging indexes in the control group before and after treatment (P > 0.05). There was no significant difference in the results of relevant imaging indicators in the treatment group before and after treatment (P > 0.05), except for LMCA (P < 0.05). The comparison of imaging related indicators before and after treatment between the two groups showed that except for no statistically significant difference in LMCA and RMCA before treatment (P > 0.05), all other indicators had statistical significance (P < 0.05). The results of relevant laboratory indexes in control group before and after treatment were statistically significant (P < 0.05). The results of relevant laboratory indexes before and after treatment in the treatment group were statistically significant (P < 0.05). The results of relevant laboratory indicators were compared between the two groups, except for the results of SAA, IL-6 and PCT before treatment, which were not statistically significant (P > 0.05), the differences in all other indicators were statistically significant (P Conclusion: The combination of echocardiography with blood SAA, IL-6, PCT, and CRP detection can establish the optimal evaluation plan for accurate and effective diagnosis, treatment, and prognosis of Kawasaki disease in children, providing more accurate and reliable diagnostic and treatment methods and laboratory data for clinical practice, and thus providing strong protection for children’s health.展开更多
文摘目的:探讨老年髋部骨折手术患者实施超前镇痛联合多模式镇痛的效果及对IL-6、CRP水平的影响。方法:择取2019年1月-2020年1月笔者所在医院80例老年髋部骨折手术患者为研究对象,按照随机数字表法将其分为对照组和观察组,各40例。对照组实施常规硬膜外自控镇痛,观察组实施超前镇痛联合多模式镇痛。比较两组不同时间VAS评分及IL-6、CRP水平。结果:观察组术后1、24、72 h、1周VAS评分均低于对照组,差异有统计学意义(P<0.05)。观察组术前1 h、术后1、24、48 h IL-6、CRP水平均低于对照组,差异有统计学意义(P<0.05)。结论:老年髋部骨折手术患者实施超前镇痛联合多模式镇痛,可大幅减轻患者术后疼痛,减轻炎性反应,从而加快术后康复,值得临床参考借鉴。
文摘Objective: To understand the application of echocardiography combined with blood SAA, IL-6, PCT, and CRP detection in the diagnosis and treatment of Kawasaki disease in children. Methods: 56 children with Kawasaki disease were selected as the study subjects as the treatment group, and 54 children with other diseases during the same period were selected as the control group. Echocardiography, blood SAA, IL-6, PCT and CRP were detected before and after treatment to observe the results of the two groups. A database was established to compare the changes of various indicators between the two groups, as well as the application value of each indicator in the clinical diagnosis and treatment of Kawasaki disease, and the pros and cons of the application of each indicator in the diagnosis and treatment of children with Kawasaki disease were analyzed, so as to provide a clearer early warning mechanism for the clinical diagnosis and treatment of children with Kawasaki disease. Results: There was no significant difference in the results of related imaging indexes in the control group before and after treatment (P > 0.05). There was no significant difference in the results of relevant imaging indicators in the treatment group before and after treatment (P > 0.05), except for LMCA (P < 0.05). The comparison of imaging related indicators before and after treatment between the two groups showed that except for no statistically significant difference in LMCA and RMCA before treatment (P > 0.05), all other indicators had statistical significance (P < 0.05). The results of relevant laboratory indexes in control group before and after treatment were statistically significant (P < 0.05). The results of relevant laboratory indexes before and after treatment in the treatment group were statistically significant (P < 0.05). The results of relevant laboratory indicators were compared between the two groups, except for the results of SAA, IL-6 and PCT before treatment, which were not statistically significant (P > 0.05), the differences in all other indicators were statistically significant (P Conclusion: The combination of echocardiography with blood SAA, IL-6, PCT, and CRP detection can establish the optimal evaluation plan for accurate and effective diagnosis, treatment, and prognosis of Kawasaki disease in children, providing more accurate and reliable diagnostic and treatment methods and laboratory data for clinical practice, and thus providing strong protection for children’s health.