An automatic IQ phase calibration method implemented in a 2.4GHz direct conversion receiver is proposed. It uses a delay locked loop （DLL） with a proposed quadrature phase detector to greatly reduce the phase error....An automatic IQ phase calibration method implemented in a 2.4GHz direct conversion receiver is proposed. It uses a delay locked loop （DLL） with a proposed quadrature phase detector to greatly reduce the phase error. The receiver is fabricated in a 0.18μm CMOS process. Measurements show that the IQ phase error can be calibrated within 1°,which satisfies the system requirement.展开更多
Objective: To demonstrate that high IQ children and adolescents diagnosed with ADHD tend to suffer from executive function (EF) impairments that: a) can be identified with a combination of standardized measures and no...Objective: To demonstrate that high IQ children and adolescents diagnosed with ADHD tend to suffer from executive function (EF) impairments that: a) can be identified with a combination of standardized measures and normed self-report data;and b) occur more frequently in this group than in the general population. Method: From charts of 117 children and adolescents aged 6 to 17 years with high IQ ( ≥ 120) who fully met DSM-IV diagnostic criteria for ADHD, data on 8 normed measures of executive function (EF) were extracted: IQ index scores for working memory and processing speed, a standardized measure of auditory verbal memory, and 5 clusters of the Brown ADD Scale, a normed, age-graded rating scale for ADHD-related executive function impairments in daily life. Significant impairment was computed for each individual relative to age-appropriate norms for each measure and comparisons were made to base-line rates in the general population. Results: Sixty-two percent of participants were significantly impaired on at least 5 of these 8 markers of EF. Chi-square comparisons of scores from these high IQ participants were significantly different (p < 0.001) from standardization norms for each of the eight EF measures. Conclusions: High IQ children and adolescents with ADHD, despite their cognitive strengths, tend to suffer from significant impairments of executive functions that can be assessed with these measures;incidence of these impairments is significantly greater than in the general population. These results are fully consistent with data on high IQ adults diagnosed with ADHD.展开更多
为实现高速光通信系统高效低成本测试的目标,基于施密特正交化过程(GSOP,Gram-Schmidt orthogonalizationprocedure),提出了一种适用于偏振复用—多进制正交幅度调制(PDM-MQAM)相干光通信系统的正交不平衡损伤估计(IQ-ImEstimation, IQ ...为实现高速光通信系统高效低成本测试的目标,基于施密特正交化过程(GSOP,Gram-Schmidt orthogonalizationprocedure),提出了一种适用于偏振复用—多进制正交幅度调制(PDM-MQAM)相干光通信系统的正交不平衡损伤估计(IQ-ImEstimation, IQ imbalance estimation)算法。根据同相信号和正交信号两路信号功率关系及相关性,设计幅度失配估计和相位失配估计2种方案。通过对34GBaudPDM-MQAM相干光通信系统进行仿真与实验,验证了IQ-ImEstimation算法的正确性和有效性。展开更多
More than 40%of newly discovered drugs have little or no water solubility which presents a serious challenge to the successful development and commercialization of new drugs in the pharmaceutical industry.Additionally...More than 40%of newly discovered drugs have little or no water solubility which presents a serious challenge to the successful development and commercialization of new drugs in the pharmaceutical industry.Additionally,more than 90%of drugs approved since 1995 have poor solubility,poor permeability,or both.Therefore,it may be necessary to increase the dose of a poorly soluble drug to obtain the required efficacy which can lead to more side effects and higher cost to the patient.Performance of drugs can be improved by decreasing the particle size and,at the same time,increasing specific surface area,dissolution rate and the bioavailability of the drug in the human body.The routes of administration are different and listed as 60%for oral,5%for pulmonary,5%for ocular,5%for topical and 25%for injectable,approximately.The injectable drugs are the most interesting ones for nanoization,because smaller particles will increase performance,and will be useful when using micro needles.In a typical manufacturing process of APIs(active pharmaceutical ingredients)top down processes like high pressure homogenization and wet bead milling are used as standard methods to decrease the particle sizes down to a fineness range of 10 to 500 nanometers.展开更多
文摘An automatic IQ phase calibration method implemented in a 2.4GHz direct conversion receiver is proposed. It uses a delay locked loop （DLL） with a proposed quadrature phase detector to greatly reduce the phase error. The receiver is fabricated in a 0.18μm CMOS process. Measurements show that the IQ phase error can be calibrated within 1°,which satisfies the system requirement.
文摘Objective: To demonstrate that high IQ children and adolescents diagnosed with ADHD tend to suffer from executive function (EF) impairments that: a) can be identified with a combination of standardized measures and normed self-report data;and b) occur more frequently in this group than in the general population. Method: From charts of 117 children and adolescents aged 6 to 17 years with high IQ ( ≥ 120) who fully met DSM-IV diagnostic criteria for ADHD, data on 8 normed measures of executive function (EF) were extracted: IQ index scores for working memory and processing speed, a standardized measure of auditory verbal memory, and 5 clusters of the Brown ADD Scale, a normed, age-graded rating scale for ADHD-related executive function impairments in daily life. Significant impairment was computed for each individual relative to age-appropriate norms for each measure and comparisons were made to base-line rates in the general population. Results: Sixty-two percent of participants were significantly impaired on at least 5 of these 8 markers of EF. Chi-square comparisons of scores from these high IQ participants were significantly different (p < 0.001) from standardization norms for each of the eight EF measures. Conclusions: High IQ children and adolescents with ADHD, despite their cognitive strengths, tend to suffer from significant impairments of executive functions that can be assessed with these measures;incidence of these impairments is significantly greater than in the general population. These results are fully consistent with data on high IQ adults diagnosed with ADHD.
文摘为实现高速光通信系统高效低成本测试的目标,基于施密特正交化过程(GSOP,Gram-Schmidt orthogonalizationprocedure),提出了一种适用于偏振复用—多进制正交幅度调制(PDM-MQAM)相干光通信系统的正交不平衡损伤估计(IQ-ImEstimation, IQ imbalance estimation)算法。根据同相信号和正交信号两路信号功率关系及相关性,设计幅度失配估计和相位失配估计2种方案。通过对34GBaudPDM-MQAM相干光通信系统进行仿真与实验,验证了IQ-ImEstimation算法的正确性和有效性。
文摘More than 40%of newly discovered drugs have little or no water solubility which presents a serious challenge to the successful development and commercialization of new drugs in the pharmaceutical industry.Additionally,more than 90%of drugs approved since 1995 have poor solubility,poor permeability,or both.Therefore,it may be necessary to increase the dose of a poorly soluble drug to obtain the required efficacy which can lead to more side effects and higher cost to the patient.Performance of drugs can be improved by decreasing the particle size and,at the same time,increasing specific surface area,dissolution rate and the bioavailability of the drug in the human body.The routes of administration are different and listed as 60%for oral,5%for pulmonary,5%for ocular,5%for topical and 25%for injectable,approximately.The injectable drugs are the most interesting ones for nanoization,because smaller particles will increase performance,and will be useful when using micro needles.In a typical manufacturing process of APIs(active pharmaceutical ingredients)top down processes like high pressure homogenization and wet bead milling are used as standard methods to decrease the particle sizes down to a fineness range of 10 to 500 nanometers.
