IRID试剂盒对糖尿病肾病早期诊断的价值

探讨IRID试制盒对糖尿病肾病早期诊断的价值。应用改良单向免疫扩散法（improvedsinglerarialimmunodiffusionIRID）试剂盒测定糖尿病人12小时夜间尿微量白蛋白。结果83例患者显示26例异常。凡尿蛋白定性测定和24小时尿蛋白定量异常者．尿微量白蛋白均异常．面前二者均正常的77例中有20例尿微量白蛋白异常。提示IRID试剂盒有诊断糖尿病早期肾病的价值。

Pressure-induced anomalous insulating behavior in frustrated iridate La_(3)Ir_(3)O_(11)

The geometrically frustrated iridate La_(3)Ir_(3)O_(11) with strong spin–orbit coupling and fractional valence was recently predicted to be a quantum spin liquid candidate at ambient conditions. Here, we systematically investigate the evolution of structural and electronic properties of La_(3)Ir_(3)O_(11) under high pressure. Electrical transport measurements reveal an abnormal insulating behavior rather than metallization above a critical pressure P_(c) ~ 38.7 GPa. Synchrotron x-ray diffraction(XRD)experiments indicate the stability of the pristine cubic KSbO_(3)-type structure up to 73.1 GPa. Nevertheless, when the pressure gradually increases across P_(c), the bulk modulus gets enhanced and the pressure dependence of bond length d_(Ir-Ir) undergoes a slope change. Consistent with the XRD data, detailed analyses of Raman spectra reveal an abnormal redshift of Raman mode and a change of Raman intensity around P_(c). Our results demonstrate that the pressure-induced insulating behavior in La_(3)Ir_(3)O_(11) can be assigned to the structural modification, such as the distortion of IrO_6 octahedra. These findings will shed light on the emergent abnormal insulating behavior in other 5 d iridates reported recently.

Effect of CO_2 laser sclerectomy with iridectomy on ocular hypertension in rabbits

AIM:To evaluate the efficiency and safety of an optimized CO2 Laser glaucoma surgery system for laser sclerectomy with iridectomy.METHODS:Rabbit trials were performed to evaluate the efficiency and safety.RESULTS:IOP was significantly decreased in laser group compared with trabeculectomy group(P<0.05) from 7th postoperative day to 60th day.Compared with trabeculectomy group,histopathology studies confirmed fewer complications and better effects were found in laser group.CONCLUSION:CO2 laser sclerectomy with iridectomy is effective and safe in terms of IOP lowering.

Evolution of Magnetic and Transport Properties in Pyrochlore Iridates A2Ir2O7(A=Y,Eu,Bi)

We study the structure, magnetization, electrical transport properties and heat capacity of the pyrochlore iridates A2Ir2O7（A=Y, Eu, Bi）. It is found that magnetic frustration and long-range magnetic order coexist in Y2Ir2O7 and Eu2Ir2O7, while Bi2Ir2O7 shows magnetic frustration or short-range magnetic order without long-range magnetic order. The former two compounds show insulating behavior. However, the latter one shows metallic behavior. The variations of the radius of A-site ion affect the conduction bandwidth, correlation and Ir-Ir exchange energy, which in turn determine transport properties and magnetic properties. We also find that the antiferromagnetic ordering of pyrochlore iridates is weakly frustrated. The all-in/all-out type of anisotropy based on spin-orbit coupling plays a key role in releasing the frustration.

Emergent quantum phenomena in atomically engineered iridate heterostructures

Over the last few years,researches in iridates have developed into an exciting field with the discovery of numerous emergent phenomena,interesting physics,and intriguing functionalities.Among the studies,iridate-based artificial structures play a crucial role owing to their extreme flexibility and tunability in lattice symmetry,chemical composition,and crystal dimensionality.In this article,we present an overview of the recent progress regarding iridate-based artificial structures.We first explicitly introduce several essential concepts in iridates.Then,we illustrate important findings on representative SrIrO_(3)/SrTiO_(3) superlattices,heterostructures comprised of SrIrO3 and magnetic oxides,and their response to external electric-field stimuli.Finally,we comment on existing problems and promising future directions in this exciting field.

Enhanced conductivity and weakened magnetism in Pb-doped Sr_(2)IrO_(4)

Group IV element Pb has been selected as the dopant to dope at the Sr site of Sr_(2)IrO_(4). It is exciting to find that the single-phase crystal structure could be maintained with a high Pb doping level of up to x=0.3 in Sr_(2-x)Pb_(x)IrO_(4). The mapping data obtained from energy-dispersive x-ray spectroscopy analyses give solid evidence that the Pb ions are uniformly distributed in the Sr_(2)IrO_(4) matrix. The incorporation of Pb leads to a moderate depression of the canted antiferromagnetic ordering state. The electrical conductivity could be greatly enhanced when the Pb doping content is higher than x=0.2.The present results give a fresh material base to explore new physics in doped Sr_(2)IrO_(4) systems.

改良单向免疫扩散法在糖尿病肾病中的应用

为建立检测糖尿病早期肾损害的新方法．用自行研制的改良单向免疫扩散法，测定了100例糖尿病人尿白蛋白（AIb）和转铁蛋白（Tf）的排出率，并与年龄相匹配的健康人比较．确定了正常参考值（95％可信限）．两项指标呈高度相关．使用两种指标比用一项指标更具有诊断价值．

纳米TiN粉体氧化制备铱钛氧化物为中间层的钛基氧化铱电极

以纳米TiN粉体和氯铱酸的混合液为涂液,采用浸渍-热分解法制备了含IrOx-TiO2中间层的钛基氧化铱电极.利用扫描电镜、X射线能谱和X射线衍射技术并结合电化学方法考察了中间层的组成和焙烧温度对电极的电催化性能和使用寿命的影响.结果表明,IrOx-TiO2中间层的加入没有改变传统的钛基氧化铱电极的形貌特征和组成,并使电极具有相同的电催化响应特性,同时大大提高了钛基氧化铱电极的使用寿命.制备钛基氧化铱电极的最优条件为焙烧温度450℃,中间层中Ir/Ti摩尔比为1.5。

Role of bevacizumab intraocular injection in the management of neovascular glaucoma

AIM:To assess the long-term effects of intraocular bevacizumab(Avastin)injections as an adjunctive drug to manage patients with neovascular glaucoma(NVG).METHODS:A retrospective study was conducted consisting of 34 eyes with secondary NVG caused by proliferative diabetic retinopathy(n=25),ischemic central retinal vein occlusion(n=8),and retinal ischemia resulting from persistent detachment(n=1)were managed by intraocular injections of bevacizumab(1.25 mg/0.05 m L),in addition to other treatments.The main outcome measure was the change in the degree of iris neovascularization.Secondary outcomes included intraocular pressure and the number of additional interventions or antiglaucoma medications administered after injection.RESULTS:All patients were followed-up for at least 12 mo.At the last follow-up,complete regression of rubeosis irides was detectable in 13(38.2%)eyes and incomplete regression in 21 eyes(61.8%).The mean intraocular pressure was 45.32±7.185 mm Hg at baseline and significantly decreased to 26.15±5.679 mm Hg at the last follow-up visit(P=0.000005).Patients received an average of 4.97 injections.As additional treatments,12 eyes(35%)received laser photocoagulation and 6 eyes(18%)underwent retinocryopexy.No further treatment was needed in 16 eyes(47.1%).CONCLUSION:Intravitreal bevacizumab injection can have a favorable effect in controlling intraocular pressure and pain control in patients with NVG because it decreases the angiogenesis and helps to augment the results of conventional procedures.The primary cause of retinal ischemia should be always targeted.

虹膜膈人工晶状体用于治疗外伤性白内障伴虹膜缺损的临床观察

目的:分析虹膜膈人工晶状体植入术对外伤白内障合并无虹膜或虹膜大部分缺损患者的临床效果。方法:采用植入带虹膜膈人工晶状体治疗9例9眼无虹膜或大部分无虹膜的外伤性白内障患者,观察视力及各种手术并发症。结果:全部病例带虹膜膈人工晶状体植入成功,术后视力均有不同程度提高(指数/眼前～0.6),8例畏光症状全部消除,1例明显减轻。1例人工晶状体襻折断,3例发生睫状体少量出血,3例角膜水肿,5例葡萄膜炎,4例继发性青光眼,1例大泡性角膜炎。结论:带虹膜膈人工晶状体对无虹膜或大部分虹膜缺损的外伤性白内障患者提供了一个行之有效的治疗方法。

虹膜膈人工晶状体治疗外伤性白内障合并虹膜缺损的临床应用

目的探讨虹膜膈人工晶体植入术对外伤白内障合并无虹膜或虹膜大部分缺损患者的临床效果。方法采用植入带虹膜膈人工晶体治疗22例(22眼)无虹膜或大部分无虹膜的外伤性白内障患者,观察视力及各种手术并发症。结果全部病例带虹膜膈人工晶体植入成功,术后视力均有不同程度提高(眼前指数～0.6),18例畏光症状全部消除,4例明显减轻。1例人工晶状体襻折断,2例发生睫状体少量出血,10例角膜水肿,6例葡萄膜炎,6例继发性青光眼,13眼术后散光,经处理全部得到控制,1例大泡性角膜炎。结论带虹膜膈人工晶体对无虹膜或大部分虹膜缺损的外伤性白内障患者提供了一个行之有效的方法。

Growth of high quality Sr2IrO4 epitaxial thin films on conductive substrates

Ruddlesden–Popper iridium oxides have attracted considerable interest because of the many proposed novel quantum states that arise from the large spin–orbit coupling of the heavy iridium atoms in them.A prominent example is the single layer Sr2IrO4, in which superconductivity has been proposed under electron doping.However, the synthesis of Sr2IrO4 high quality thin films has been a huge challenge due to the easy formation of impurities associated with different numbers of SrO layers.Thus techniques to optimize the growth of pure phase Sr2IrO4 are urgently required.Here we report the deposition of high quality Sr2IrO4 thin films on both insulating SrTiO3 and conducting SrTiO3:Nb substrates using pulsed laser deposition assisted with reflective high-energy electron diffraction.The optimal deposition temperature of Sr2IrO4 epitaxial films on SrTiO3:Nb substrates is about 90℃ lower than that on SrTiO3 substrates.The electrical transports of high quality Sr2IrO4 films are measured, which follow the three-dimensional Mott variable-range hopping model.The film magnetizations are measured, which show weak ferromagnetism below ~240 K with a saturation magnetization of~ 0.2 μB/Ir at 5 K.This study provides applicable methods to prepare high quality 5 d Sr2IrO4 epitaxial films, which could be extended to other Ruddlesden–Popper phases and potentially help the future study of exotic quantum phenomena in them.

上皮植入性虹膜囊肿的激光治疗

目的：观察Ｎｄ：ＹＡＧ激光治疗上皮植入性虹膜囊肿的疗效。方法：治疗前详细了解囊肿与周围组织的关系，首先激穿囊肿前壁，使腔内液体引流，然后降低能量，照射囊肿后壁及周围组织，以尽可能破坏上皮细胞，减少复发。激光治疗单脉冲能量为０．４ＭＪ，每次治疗总量为２０～３５ＭＪ。结果：所有治疗眼的视力均有不同程度提高。经术后６个月～１年的随访观察，未见明显复发。结论：激光治疗上皮植入性虹膜囊肿，既可破坏囊壁的上皮细胞，又可避免和减少囊肿邻近组织的损伤及反应，以尽可能多地保留和恢复有效视功能，以避免患者因再次手术所带来的痛苦。

Growth of high-quality perovskite (110)-SrIrO_3 thin films using reactive molecular beam epitaxy

Recently, 5d transition metal iridates have been reported as promising materials for the manttfacture of exotic quan- tum states. Apart from the semimetallic ground states that have been observed, perovskite SrlrO3 is also predicted to have a lattice-symmetrically protected topological state in the （110） plane due to its strong： spin-orbil coupling and electron correlation. Compared with non-polar （001）-SflrO3, the especial polarity of （110）-SrIrC）3 undoubtedly adds the： difficulty of fabrication and largely impedes the research on its surface states. Here, we have successfully synthesized high-quality （110）-SflrO3 thin films on （110）-SrTiO3 substrates by reactive molecular beam epitaxy fi^r the first time. Both reflec- tion high-energy electron diffraction pattems and x-ray diffraction measurements suggest the expected orientation and outstanding crystallinity. A （1 × 2） surface reconstruction driven from the surface instabiJity, the. same as that reported in （110）-SrTiO3, is observed. The electric transport measurements uncover that （110）-SrIrO3 exhibits a more prominent semimetallic property in comparison to （001）-SrIrO3.

Epitaxial growth and transport properties of compressively-strained Ba_(2)IrO_(4) films

Ba_(2)IrO_(4) is a sister compound of the widely investigated Sr_(2)IrO_(4) and has no IrO_(6) octahedral rotation nor net canted antiferromagnetic moment,thus it acts as a system more similar to the high-T_(c) cuprate.In this work,we synthesize the Ba_(2)IrO_(4) epitaxial films by reactive molecular beam epitaxy and study their crystalline structure and transport properties under biaxial compressive strain.High resolution scanning transmission electron microscopy and x-ray diffraction confirm the high quality of films with partial strain relaxation.Under compressive epitaxial strain,the Ba_(2)IrO_(4) exhibits the strain-driven enhancement of the conductivity,consistent with the band gap narrowing and the stronger hybridization of Ir-t_(2g) and O-2p orbitals predicted in the first-principles calculations.

Single crystal growth and electronic structure of Rh-doped Sr_(3)Ir_(2)O_(7)

Ruddlesden-Popper iridate Sr_(3)Ir_(2)O_(7)is a spin-orbit coupled Mott insulator.Hole doped Sr_(3)Ir_(2)O_(7)provides an ideal platform to study the exotic quantum phenomena that occur near the metal-insulator transition(MIT)region.Rh substitution of Ir is an effective method to induce hole doping into Sr_(3)Ir_(2)O_(7).However,the highest doping level reported in Sr_(3)(Ir_(1-x)Rh_(x))_(2)O_(7)single crystals was only around 3%,which is far from the MIT region.In this paper,we report the successful growth of single crystals of Sr3(Ir_(1-x)Rh_(x))_(2)O_(7)with a doping level of~9%.The samples have been fully characterized,demonstrating the high quality of the single crystals.Transport measurements have been carried out,confirming the tendency of MIT in these samples.The electronic structure has also been examined by angle-resolved photoemission spectroscopy(ARPES)measurements.Our results establish a platform to investigate the heavily hole doped Sr_(3)Ir_(2)O_(7) compound,which also provide new insights into the MIT with hole doping in this material system.

ISAR Imaging and Cross-Range Scaling Based on Image Rotation Correlation

With the rapid advancement of technology,not only do we need to acquire a clear in-verse synthetic aperture radar(ISAR)image,but also the real size of the target on the imaging plane,so it’s particularly important for the ISAR to rescale the images.That is,the ISAR image which is in the range-Doppler domain is converted into the range-azimuth domain.Actually,the key point to solving the problem is to estimate the rotation parameters.In this paper,a new scheme to rescale the images is proposed.For the sake of solving the problem of two-dimensional image blur and target high-speed,the instantaneous range instantaneous Doppler(IRID)method is used to obtain ISAR images,and the rotation parameters are estimated by comparing the rotation correlation of the two images.Using this method,the error of the estimated rotation parameters is greatly reduced,so that the target can be rescaled accurately.The simulation results verify the ef-fectiveness of the proposed algorithm.

Novel Synthesis Method of Nonst0ichiometric Na2-xlrO3 Crystal Structure, Transport and Magnetic Properties

Transition metal oxides with 4d or 5d metals are of great interest due to the competing interactions, of the Coulomb repulsion and the itineracy of the d-electrons, opening a possibility of building new quantum ground states. Particularly the 5d metal oxides containing Iridium have received significant attention within the last years, due to their unexpected physical properties, caused by a strong spin orbit coupling observed in It（IV）. A prominent example is the Mott-insulator Sr2IrO4. Another member of this family, the honeycomb lattice compound Na2IrO3, also being a Mott-insulator having, most probably, a Kitaev spin liquid ground state. By deintercalating sodium from Na2IrO3, the authors were able to synthesize a new honeycomb lattice compound with more than 50% reduced sodium content. The reduction of the sodium content in this layered compound leads to a change of the oxidation state of iridium from ＋ IV to ＋ V/＋ VI and a symmetry change from C2/c to P-3. This goes along with significant changes of the physical properties. Besides the vanishing magnetic ordering at 15 K, also the transport properties changes and instead insulating semiconducting properties are observed.

我国产业结构变动趋势的合理化分析

随着我国社会主义市场经济体制的建立和完善,各种经济成份的比例、产业结构以及国有资产结构状况等方面发生了巨大的变化。据研究,人均国民生产总值在300-1000美元之间的国家、产业结构处于剧烈的变动和调整之中,目前我国人均国民生产总值为400多美元,因此,我国的产业结构正处于这一时期。由于我国的产业结构尚处于工业化初级阶段,各地区间发展又不平衡。

自旋-轨道耦合型莫特绝缘体Sr2IrO4的高压拉曼光谱

5d过渡金属化合物内部的电子相互作用(U)、自旋-轨道耦合(SOC)、晶体场效应呈现既耦合又竞争的复杂关系。这些耦合竞争关系可以在温度、磁场或压力调控下诱发许多新奇的电磁性质,成为当前凝聚态物理的研究热点之一。通过对目前研究最多的化合物Sr2IrO4单晶进行常温高压下的拉曼光谱分析发现,加压至19.6~22.2 GPa时,拉曼光谱在波数为199 cm–1处出现新峰,清楚表明结构发生了相变,而该相变在此前一直无法确认。进一步的研究表明:这种结构相变的发生独立于低温下的磁性相变,可以通过自旋-轨道耦合对高压下Sr2IrO4的磁有序消失起到决定性作用。实验结果揭示了利用莫特绝缘体晶格变化来调控其电磁特性的新途径,也为未来设计新型功能材料提供了新思路。